Mechanisms of cooperation in cancer nanomedicine: Towards systems nanotechnology

Trends in Biotechnology

Volumn 32, Issue 9, 2014, Pages 448-455

  Hauert, Sabine ^a,b,c   Bhatia, Sangeeta N ^a,b,d,e  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d Massachusetts Institute of Technology Cambridge   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cancer; Cooperation; Nanoparticles; Swarming; Systems nanotechnology

Indexed keywords

BEHAVIORAL RESEARCH; BIOMIMETICS; NANOPARTICLES; TUMORS;

BIOMIMETIC STRATEGY; CANCER; CO-OPERATIVE BEHAVIORS; COMPUTATIONAL TOOLS; COOPERATION; SELF ORGANIZED SYSTEMS; SWARMING; SYSTEMS APPROACH;

NANOSYSTEMS;

BIOMIMETIC MATERIAL; NANOPARTICLE;

CHEMICAL STRUCTURE; COOPERATION; MATERIAL COATING; NANOMEDICINE; NANOTECHNOLOGY; PREDICTIVE VALUE; PRIORITY JOURNAL; REVIEW; SURFACE PROPERTY; TUMOR MICROENVIRONMENT; HUMAN; MEDICAL RESEARCH; NEOPLASMS; PROCEDURES; TRENDS;

BIOMEDICAL RESEARCH; HUMANS; NANOMEDICINE; NANOTECHNOLOGY; NEOPLASMS;

EID: 84906306628     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2014.06.010     Document Type: Review

References (108)

1. Bao G., et al. Multifunctional nanoparticles for drug delivery and molecular imaging. Annu. Rev. Biomed. Eng. 2013, 15:253-282.
2. Davis M.E., et al. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 2008, 7:771-782.
3. Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat. Rev. Clin. Oncol. 2010, 7:653-664.
4. Ferrari M. Frontiers in cancer nanomedicine: directing mass transport through biological barriers. Trends Biotechnol. 2010, 28:181-188.
5. Brannon-Peppas L., Blanchette J.O. Nanoparticle and targeted systems for cancer therapy. Adv. Drug Deliv. Rev. 2012, 64:206-212.
6. Ruoslahti E., et al. Targeting of drugs and nanoparticles to tumors. J. Cell Biol. 2010, 188:759-768.
7. Kanapathipillai M., et al. Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. Adv. Drug Deliv. Rev. 2014, 10.1016/j.addr.2014.05.005.
8. Cho K., et al. Therapeutic nanoparticles for drug delivery in cancer. Clin. Cancer Res. 2008, 14:1310-1316.
9. Wang A.Z., et al. Nanoparticle delivery of cancer drugs. Annu. Rev. Med. 2012, 63:185-198.
10. Ryu J.H., et al. Tumor-targeting multi-functional nanoparticles for theragnosis: new paradigm for cancer therapy. Adv. Drug Deliv. Rev. 2012, 64:1447-1458.
11. Melancon M., et al. Cancer theranostics with near-infrared light-activatable multimodal nanoparticles. Acc. Chem. Res. 2011, 44:947-956.
12. Pissuwan D., et al. Therapeutic possibilities of plasmonically heated gold nanoparticles. Trends Biotechnol. 2006, 24:62-67.
13. Kanasty R., et al. Delivery materials for siRNA therapeutics. Nat. Mater. 2013, 12:967-977.
14. Moon J.J., et al. Engineering nano- and microparticles to tune immunity. Adv. Mater. 2012, 24:3724-3746.
15. Taurin S., et al. Anticancer nanomedicine and tumor vascular permeability; where is the missing link?. J. Control. Release 2012, 164:265-275.
16. Hauert S., et al. A computational framework for identifying design guidelines to increase the penetration of targeted nanoparticles into tumors. Nano Today 2013, 8:566-576.
17. Thurber G.M., Weissleder R. A systems approach for tumor pharmacokinetics. PLoS ONE 2011, 6:e24696.
18. Wittrup K.D., et al. Practical theoretic guidance for the design of tumor-targeting agents. Methods Enzymol. 2012, 503:255-268.
19. Bonabeau E., et al. Swarm Intelligence: From Natural to Artificial Systems 1999, Oxford University Press.
20. Camazine S., et al. Self-Organization in Biological Systems 2003, Princeton University Press.
21. Couzin I.D. Collective cognition in animal groups. Trends Cogn. Sci. 2009, 13:36-43.
22. Krause J., et al. Swarm intelligence in animals and humans. Trends Ecol. Evol. 2010, 25:28-34.
23. Şahin E. Swarm robotics: from sources of inspiration to domains of application. Swarm Robotics 2005, 10-20. Springer. E. Şahin, W.M. Spears (Eds.).
24. Winfield A.F.T., et al. Towards dependable swarms and a new discipline of swarm engineering. Swarm Robotics 2005, 126-142. Springer. E. Şahin, W.M. Spears (Eds.).
25. Hauert S., et al. Reynolds flocking in reality with fixed-wing robots: communication range vs. maximum turning rate. IEEE/RSJ International Conference on Intelligent Robots and Systems 2011, 5015-5020.
26. Kernbach S. Handbook of Collective Robotics: Fundamentals and Challenges 2013, Pan Stanford Publishing.
27. Werfel J., et al. Designing collective behavior in a termite-inspired robot construction team. Science 2014, 343:754-758.
28. Nam J., et al. pH-induced aggregation of gold nanoparticles for photothermal cancer therapy. J. Am. Chem. Soc. 2009, 131:13639-13645.
29. Perrault S.D., Chan W.C.W. In vivo assembly of nanoparticle components to improve targeted cancer imaging. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:11194-11199.
30. Godin B., et al. Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics. Acc. Chem. Res. 2011, 44:979-989.
31. Wong C., et al. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:2426-2431.
32. Kwong G.A., et al. Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease. Nat. Biotechnol. 2013, 31:63-70.
33. Park J-H., et al. Cooperative nanomaterial system to sensitize, target, and treat tumors. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:981-986.
34. von Maltzahn G., et al. Nanoparticles that communicate in vivo to amplify tumour targeting. Nat. Mater. 2011, 10:545-552.
35. Phan J.H., et al. Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends Biotechnol. 2009, 27:350-358.
36. Florence A.T. "Targeting" nanoparticles: the constraints of physical laws and physical barriers. J. Control. Release 2012, 164:115-124.
37. Abeylath S.C., et al. Combinatorial-designed multifunctional polymeric nanosystems for tumor-targeted therapeutic delivery. Acc. Chem. Res. 2011, 44:1009-1017.
38. Xu J., et al. Future of the particle replication in nonwetting templates (PRINT) technology. Angew. Chem. Int. Ed. Engl. 2013, 52:6580-6589.
39. Vickerman V., et al. Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging. Lab Chip 2008, 8:1468-1477.
40. Weissleder R., Pittet M.J. Imaging in the era of molecular oncology. Nature 2008, 452:580-589.
41. Deisboeck T.S., Couzin I.D. Collective behavior in cancer cell populations. Bioessays 2009, 31:190-197.
42. Forbes N.S. Engineering the perfect (bacterial) cancer therapy. Nat. Rev. Cancer 2010, 10:785-794.
43. Petros R.A., DeSimone J.M. Strategies in the design of nanoparticles for therapeutic applications. Nat. Rev. Drug Discov. 2010, 9:615-627.
44. Wang J., et al. More effective nanomedicines through particle design. Small 2011, 7:1919-1931.
45. Dreaden E.C., et al. Size matters: gold nanoparticles in targeted cancer drug delivery. Ther. Deliv. 2012, 3:457-478.
46. Kievit F.M., Zhang M. Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers. Adv. Mater. 2011, 23:217-247.
47. Choi H.S., et al. Renal clearance of quantum dots. Nat. Biotechnol. 2007, 25:1165-1170.
48. Longmire M., et al. Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats. Nanomedicine (Lond.) 2008, 3:703-717.
49. Maeda H., et al. The EPR effect for macromolecular drug delivery to solid tumors: improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo. Adv. Drug Deliv. Rev. 2012, 65:71-79.
50. Perrault S.D., et al. Mediating tumor targeting efficiency of nanoparticles through design. Nano Lett. 2009, 9:1909-1915.
51. Venkataraman S., et al. The effects of polymeric nanostructure shape on drug delivery. Adv. Drug Deliv. Rev. 2011, 63:1228-1246.
52. Owens D.E., Peppas N.A. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int. J. Pharm. 2006, 307:93-102.
53. Rodriguez P.L., et al. Minimal "self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles. Science 2013, 339:971-975.
54. Harris T.J., et al. Protease-triggered unveiling of bioactive nanoparticles. Small 2008, 4:1307-1312.
55. Poon Z., et al. Layer-by-layer nanoparticles with a pH-sheddable layer for in vivo targeting of tumor hypoxia. ACS Nano 2011, 5:4284-4292.
56. Romberg B., et al. Sheddable coatings for long-circulating nanoparticles. Pharm. Res. 2008, 25:55-71.
57. Kamaly N., et al. Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chem. Soc. Rev. 2012, 41:2971-3010.
58. Pearce T.R., et al. Peptide targeted lipid nanoparticles for anticancer drug delivery. Adv. Mater. 2012, 24:3803-3822. 3710.
59. Julien D.C., et al. Utilization of monoclonal antibody-targeted nanomaterials in the treatment of cancer. MAbs 2011, 3:467-478.
60. Yang L., et al. Aptamer-conjugated nanomaterials and their applications. Adv. Drug Deliv. Rev. 2011, 63:1361-1370.
61. Valencia P.M., et al. Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles. Biomaterials 2011, 32:6226-6233.
62. Timko B.P., et al. Advances in drug delivery. Annu. Rev. Mater. Res. 2011, 41:1-20.
63. Ruoslahti E. Peptides as targeting elements and tissue penetration devices for nanoparticles. Adv. Mater. 2012, 24:3747-3756.
64. Sengupta S., et al. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature 2005, 436:568-572.
65. Ji T., et al. Using functional nanomaterials to target and regulate the tumor microenvironment: diagnostic and therapeutic applications. Adv. Mater. 2013, 25:3508-3525.
66. Waite C., Roth C. Nanoscale drug delivery systems for enhanced drug penetration into solid tumors: current progress and opportunities. Crit. Rev. Biomed. Eng. 2012, 40:21-41.
67. Silva J.M., et al. Immune system targeting by biodegradable nanoparticles for cancer vaccines. J. Control. Release 2013, 168:179-199.
68. Hou K.K., et al. Mechanisms of nanoparticle-mediated siRNA transfection by melittin-derived peptides. ACS Nano 2013, 7:8605-8615.
69. Bocci G., et al. The pharmacological bases of the antiangiogenic activity of paclitaxel. Angiogenesis 2013, 16:481-492.
70. Goodman T.T., et al. Increased nanoparticle penetration in collagenase-treated multicellular spheroids. Int. J. Nanomed. 2007, 2:265-274.
71. Zhu L., Torchilin V.P. Stimulus-responsive nanopreparations for tumor targeting. Integr. Biol. (Camb) 2013, 5:96-107.
72. Kost J., Langer R. Responsive polymeric delivery systems. Adv. Drug Deliv. Rev. 2012, 64:327-341.
73. Kumari A., et al. Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf. B Biointerfaces 2010, 75:1-18.
74. Sailor M.J., Park J-H. Hybrid nanoparticles for detection and treatment of cancer. Adv. Mater. 2012, 24:3779-3802.
75. Danhier F., et al. To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J. Control. Release 2010, 148:135-146.
76. Lin K., et al. Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis. ACS Nano 2013, 7:9001-9009.
77. Olson E.S., et al. Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:4311-4316.
78. Cole A.J., et al. Cancer theranostics: the rise of targeted magnetic nanoparticles. Trends Biotechnol. 2011, 29:323-332.
79. Derfus A.M., et al. Remotely triggered release from magnetic nanoparticles. Adv. Mater. 2007, 19:3932-3936.
80. McCarthy J.R., Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv. Drug Deliv. Rev. 2008, 60:1241-1251.
81. Mo S., et al. Ultrasound-enhanced drug delivery for cancer. Exp. Opin. Drug Deliv. 2012, 9:1525-1538.
82. Bagley A.F., et al. Plasmonic photothermal heating of intraperitoneal tumors through the use of an implanted near-infrared source. ACS Nano 2013, 7:8089-8097.
83. von Maltzahn G., et al. Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas. Cancer Res. 2009, 69:3892-3900.
84. Cheng Z., et al. Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities. Science 2012, 338:903-910.
85. Eldar-Boock A., et al. Nano-sized polymers and liposomes designed to deliver combination therapy for cancer. Curr. Opin. Biotechnol. 2013, 24:682-689.
86. Greco F., Vicent M.J. Combination therapy: opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines. Adv. Drug Deliv. Rev. 2009, 61:1203-1213.
87. Nam J., et al. pH-responsive assembly of gold nanoparticles and spatiotemporally concerted drug release for synergistic cancer therapy. ACS Nano 2013, 7:3388-3402.
88. von Maltzahn G., et al. Nanoparticle self-assembly gated by logical proteolytic triggers. J. Am. Chem. Soc. 2007, 129:6064-6065.
89. Anglin E.J., et al. Porous silicon in drug delivery devices and materials. Adv. Drug Deliv. Rev. 2008, 60:1266-1277.
90. Serda R.E., et al. Multi-stage delivery nano-particle systems for therapeutic applications. Biochim. Biophys. Acta 2011, 1810:317-329.
91. Park J-H., et al. Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery. Adv. Mater. 2010, 22:880-885.
92. Godin B., et al. An integrated approach for the rational design of nanovectors for biomedical imaging and therapy. Adv. Genet. 2010, 69:31-64.
93. Ren Y., et al. Identification and characterization of receptor-specific peptides for siRNA delivery. ACS Nano 2012, 6:8620-8631.
94. Cooper S., et al. Predicting protein structures with a multiplayer online game. Nature 2010, 466:756-760.
95. Martinez-Veracoechea F.J., Frenkel D. Designing super selectivity in multivalent nano-particle binding. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:10963-10968.
96. Florence A.T. Reductionism and complexity in nanoparticle-vectored drug targeting. J. Control. Release 2012, 161:399-402.
97. Anderson D.G., et al. A combinatorial library of photocrosslinkable and degradable materials. Adv. Mater. 2006, 18:2614-2618.
98. Green J., et al. A combinatorial polymer library approach yields insight into nonviral gene delivery. Acc. Chem. Res. 2008, 41:749-759.
99. Valencia P.M., et al. Microfluidic platform for combinatorial synthesis and optimization of targeted nanoparticles for cancer therapy. ACS Nano 2013, 7:10671-10680.
100. Douglas S.M., et al. Self-assembly of DNA into nanoscale three-dimensional shapes. Nature 2009, 459:414-418.
101. Douglas S.M., et al. A logic-gated nanorobot for targeted transport of molecular payloads. Science 2012, 335:831-834.
102. Iinuma R., et al. Polyhedra self-assembled from DNA tripods and characterized with 3D DNA-PAINT. Science 2014, 344:65-69.
103. Maune H.T., et al. Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templates. Nat. Nanotechnol. 2010, 5:61-66.
104. Amornphimoltham P., et al. Intravital microscopy as a tool to study drug delivery in preclinical studies. Adv. Drug Deliv. Rev. 2011, 63:119-128.
105. Hak S., et al. Intravital microscopy in window chambers: a unique tool to study tumor angiogenesis and delivery of nanoparticles. Angiogenesis 2010, 13:113-130.
106. Albanese A., et al. Tumour-on-a-chip provides an optical window into nanoparticle tissue transport. Nat. Commun. 2013, 4:2718.
107. Lanza R., et al. Principles of Tissue Engineering 2011, Academic Press.
108. Miller J.S., et al. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat. Mater. 2012, 11:768-774.