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Volumn 161, Issue 2, 2012, Pages 399-402

Reductionism and complexity in nanoparticle-vectored drug targeting

Author keywords

Complexity; Drug targeting; Nanoparticles; Reductionism

Indexed keywords

COMPLEX BIOLOGICAL SYSTEMS; COMPLEXITY; DRUG-TARGETING; NANO PARTICULATES; REDUCTIONISM; THEORETICAL INVESTIGATIONS;

EID: 84862638401     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.11.005     Document Type: Review
Times cited : (13)

References (26)
  • 1
    • 84862642436 scopus 로고    scopus 로고
    • Wikipedia at http://en.wikipedia.org/wiki/Reductionism.
  • 3
    • 10044298236 scopus 로고    scopus 로고
    • Reductionism and complexity in molecular biology
    • M.H.V. Van Regensmortel, Reductionism and complexity in molecular biology, EMBO Rep. 5 (2004) 1016-1020.
    • (2004) EMBO Rep. , vol.5 , pp. 1016-1020
    • Van Regensmortel, M.H.V.1
  • 4
    • 34047133228 scopus 로고    scopus 로고
    • Simplicity in biology
    • U. Alon, Simplicity in biology, Nature 444 (2007) 497.
    • (2007) Nature , vol.444 , pp. 497
    • Alon, U.1
  • 5
    • 75549087162 scopus 로고    scopus 로고
    • Nanosystem drug targeting: Facing up to complex realities
    • P. Ruenraroengsak, J.M. Cook, A.T. Florence, Nanosystem drug targeting: facing up to complex realities, J. Control. Release 141 (2010) 265-276.
    • (2010) J. Control. Release , vol.141 , pp. 265-276
    • Ruenraroengsak, P.1    Cook, J.M.2    Florence, A.T.3
  • 6
    • 24944562785 scopus 로고    scopus 로고
    • Unsatsfactory gene transfer into bone-resorbing osteoclasts with liposomal transfection systems
    • T. Laitala-Leinonen, Unsatsfactory gene transfer into bone-resorbing osteoclasts with liposomal transfection systems, J. Negat. Results Biomed. 4 (2005) 1-8.
    • (2005) J. Negat. Results Biomed. , vol.4 , pp. 1-8
    • Laitala-Leinonen, T.1
  • 7
    • 79960925147 scopus 로고    scopus 로고
    • Targeted drug delivery to tumours: Myths, reality and possibility
    • Y.H. Bae, K. Park, Targeted drug delivery to tumours: myths, reality and possibility, J. Control. Release 153 (2011) 198-205.
    • (2011) J. Control. Release , vol.153 , pp. 198-205
    • Bae, Y.H.1    Park, K.2
  • 9
    • 78650005650 scopus 로고    scopus 로고
    • Physical determinants of vascular network remodeling during tumor growth
    • M. Welter, H. Rieger, Physical determinants of vascular network remodeling during tumor growth, Eur. Phys. J. E Soft Matter 33 (2010) 149-163.
    • (2010) Eur. Phys. J. E Soft Matter , vol.33 , pp. 149-163
    • Welter, M.1    Rieger, H.2
  • 10
    • 34848918210 scopus 로고    scopus 로고
    • Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging
    • D.W. Bartlett, H. Su, I.J. Hildebrandt, W.A. Weber, M.E. Davis, Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging, Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 15549.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 15549
    • Bartlett, D.W.1    Su, H.2    Hildebrandt, I.J.3    Weber, W.A.4    Davis, M.E.5
  • 11
    • 0029932136 scopus 로고    scopus 로고
    • How do polymers prolong circulation time of liposomes?
    • V. Torchilin, How do polymers prolong circulation time of liposomes? J. Liposome Res. 6 (1996) 99-116.
    • (1996) J. Liposome Res. , vol.6 , pp. 99-116
    • Torchilin, V.1
  • 12
    • 2942679255 scopus 로고    scopus 로고
    • Causative factors behind poloxamer 188 (Pluronic F68, Flocor™)-induced complement activation in human sera. A protective role against poloxamer-mediated complement activation by elevated serum lipoprotein levels
    • S.M. Moghimi, A.C. Hunter, C.M. Dadswell, S. Savay, C.R. Alving, J. Szebeni, Causative factors behind poloxamer 188 (Pluronic F68, Flocor™)-induced complement activation in human sera. A protective role against poloxamer-mediated complement activation by elevated serum lipoprotein levels, Biochim. Biophys. Acta 1689 (2011) 103-113.
    • (2011) Biochim. Biophys. Acta , vol.1689 , pp. 103-113
    • Moghimi, S.M.1    Hunter, A.C.2    Dadswell, C.M.3    Savay, S.4    Alving, C.R.5    Szebeni, J.6
  • 13
    • 79960132035 scopus 로고    scopus 로고
    • The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles
    • E.C. Cho, Q. Zhang, Y. Xia, The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles, Nat. Nanotechnol. 6 (2011) 385-391.
    • (2011) Nat. Nanotechnol. , vol.6 , pp. 385-391
    • Cho, E.C.1    Zhang, Q.2    Xia, Y.3
  • 14
    • 0037453167 scopus 로고    scopus 로고
    • Formulation and stability of surface tethered DNA-gold-dendron nanoparticles
    • N. Hussain, B. Singh, T. Sakthivel, A.T. Florence, Formulation and stability of surface tethered DNA-gold-dendron nanoparticles, Int. J. Pharm. 25 (2003) 27-31.
    • (2003) Int. J. Pharm. , vol.25 , pp. 27-31
    • Hussain, N.1    Singh, B.2    Sakthivel, T.3    Florence, A.T.4
  • 16
    • 21344443474 scopus 로고    scopus 로고
    • Hydrophobic dendrimer-derived nanoparticles
    • B. Singh, A.T. Florence, Hydrophobic dendrimer-derived nanoparticles, Int. J. Pharm. 298 (2005) 348-353.
    • (2005) Int. J. Pharm. , vol.298 , pp. 348-353
    • Singh, B.1    Florence, A.T.2
  • 17
    • 0030758981 scopus 로고    scopus 로고
    • Long term stability of PBCA nanoparticle suspensions suggest clinical usefulness
    • P. Sommerfeld, U. Schroeder, B.A. Sabel, Long term stability of PBCA nanoparticle suspensions suggest clinical usefulness, Int. J. Pharm. 155 (1997) 201-207.
    • (1997) Int. J. Pharm. , vol.155 , pp. 201-207
    • Sommerfeld, P.1    Schroeder, U.2    Sabel, B.A.3
  • 18
    • 0029059163 scopus 로고
    • Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse
    • I.F. Uchegbu, J.A. Double, J.A. Turton, A.T. Florence, Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse, Pharm. Res. 12 (1995) 1019-1024.
    • (1995) Pharm. Res. , vol.12 , pp. 1019-1024
    • Uchegbu, I.F.1    Double, J.A.2    Turton, J.A.3    Florence, A.T.4
  • 19
    • 79960154421 scopus 로고    scopus 로고
    • The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems - A review
    • S. Fredenberg, M. Wahlgren, M. Reslow, A. Axelsson, The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems - a review, Int. J. Pharm. 415 (2011) 34-52.
    • (2011) Int. J. Pharm. , vol.415 , pp. 34-52
    • Fredenberg, S.1    Wahlgren, M.2    Reslow, M.3    Axelsson, A.4
  • 20
    • 58149340544 scopus 로고    scopus 로고
    • Early tumor drug pharmacokinetics is influenced by tumor perfusion but not plasma drug exposure
    • A. Saleem, P.M. Price, Early tumor drug pharmacokinetics is influenced by tumor perfusion but not plasma drug exposure, Clin. Cancer Res. 14 (2008) 8184-8190.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 8184-8190
    • Saleem, A.1    Price, P.M.2
  • 21
    • 73149095170 scopus 로고    scopus 로고
    • The relationship among tumor architecture, pharmacokinetics, pharmacodynamics and efficacy of bortezomib in mouse xenograft models
    • M.J. Williamson, M.D. Silva, J. Terkelsen, et al., The relationship among tumor architecture, pharmacokinetics, pharmacodynamics and efficacy of bortezomib in mouse xenograft models, Mol. Cancer Ther. 8 (2009) 3234.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 3234
    • Williamson, M.J.1    Silva, M.D.2    Terkelsen, J.3
  • 22
    • 79952373263 scopus 로고    scopus 로고
    • Statistical analysis of nanoparticle dosing in a dynamic cellular system
    • H.D. Summers, P. Ress, M.D. Holton, M.R. Brown, et al., Statistical analysis of nanoparticle dosing in a dynamic cellular system, Nat. Nanotechnol. 6 (2011) 170-174.
    • (2011) Nat. Nanotechnol. , vol.6 , pp. 170-174
    • Summers, H.D.1    Ress, P.2    Holton, M.D.3    Brown, M.R.4
  • 23
    • 34147128541 scopus 로고    scopus 로고
    • Realistic boundary conditions for stochastic simulations of reaction-diffusion processes
    • R. Erban, S.J. Chapman, Realistic boundary conditions for stochastic simulations of reaction-diffusion processes, Phys. Biol. 4 (2006) 16-28.
    • (2006) Phys. Biol. , vol.4 , pp. 16-28
    • Erban, R.1    Chapman, S.J.2
  • 24
    • 33751568004 scopus 로고    scopus 로고
    • Incorporating diffusion in complex geometries into stochastic chemical kinetics simulations
    • S.A. Isaacson, C.S. Peskin, Incorporating diffusion in complex geometries into stochastic chemical kinetics simulations, SIAM J. Sci. Comput. 28 (2006) 47-74.
    • (2006) SIAM J. Sci. Comput. , vol.28 , pp. 47-74
    • Isaacson, S.A.1    Peskin, C.S.2
  • 25
    • 36049049737 scopus 로고    scopus 로고
    • Design maps for nanoparticles targeting the diseased microvasculature
    • P. Decuzzi, M. Ferrari, Design maps for nanoparticles targeting the diseased microvasculature, Biomaterials 29 (2008) 377-384.
    • (2008) Biomaterials , vol.29 , pp. 377-384
    • Decuzzi, P.1    Ferrari, M.2
  • 26
    • 70449646515 scopus 로고    scopus 로고
    • Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS
    • T. Hara, S. Iriyama, K. Makino, H. Terada, M. Oha, Mathematical description of drug movement into tumor with EPR effect and estimation of its configuration for DDS, Colloids Surf. B Biointerfaces 75 (2010) 42-46.
    • (2010) Colloids Surf. B Biointerfaces , vol.75 , pp. 42-46
    • Hara, T.1    Iriyama, S.2    Makino, K.3    Terada, H.4    Oha, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.