Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

ACS Chemical Biology

Volumn 9, Issue 8, 2014, Pages 1736-1746

  Becher, Isabelle ^a   Dittmann, Antje ^a   Savitski, Mikhail M ^a   Hopf, Carsten ^a   Drewes, Gerard ^a   Bantscheff, Marcus ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZAMIDE DERIVATIVE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID DERIVATIVE; ISOPROTEIN; REPRESSOR PROTEIN; TACEDINALINE; TRANSCRIPTION FACTOR SIN3A;

ACETYLATION; ARTICLE; BINDING KINETICS; CHEMOPROTEOMICS; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG SELECTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; K562 CELL LINE; PRIORITY JOURNAL; PROTEOMICS; TIME; ANTAGONISTS AND INHIBITORS; BINDING SITE; KINETICS; MASS SPECTROMETRY; METABOLISM;

ACETYLATION; BENZAMIDES; BINDING SITES; HISTONE DEACETYLASE INHIBITORS; KINETICS; MASS SPECTROMETRY; PROTEOMICS; REPRESSOR PROTEINS;

EID: 84906260520     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500235n     Document Type: Article

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