-
1
-
-
34848878406
-
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids
-
DOI 10.1074/jbc.M702810200
-
Almeida M, Han L, Martin-Millan M, Plotkin LI, Stewart SA, Roberson PK, Kousteni S, O'Brien CA, Bellido T, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC (2007) Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem 282(37):27285-27297. doi:10.1074/jbc.M702810200 (Pubitemid 47501960)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.37
, pp. 27285-27297
-
-
Almeida, M.1
Han, L.2
Martin-Millan, M.3
Plotkin, L.I.4
Stewart, S.A.5
Roberson, P.K.6
Kousteni, S.7
O'Brien, C.A.8
Bellido, T.9
Parfitt, A.M.10
Weinstein, R.S.11
Jilka, R.L.12
Manolagas, S.C.13
-
2
-
-
38949119423
-
Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3
-
Azad MB, Chen Y, Henson ES, Cizeau J, McMillan-Ward E, Israels SJ, Gibson SB (2008) Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. Autophagy 4(2):195-204 (Pubitemid 351231183)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 195-204
-
-
Azad, M.B.1
Chen, Y.2
Henson, E.S.3
Cizeau, J.4
McMillan-Ward, E.5
Israels, S.J.6
Gibson, S.B.7
-
3
-
-
79960822419
-
Autophagy in aging and Alzheimer's disease: Pathologic or protective?
-
doi:10.3233/jad-2011-101989
-
Barnett A, Brewer GJ (2011) Autophagy in aging and Alzheimer's disease: pathologic or protective? JAD 25(3):385-394. doi:10.3233/jad-2011-101989
-
(2011)
JAD
, vol.25
, Issue.3
, pp. 385-394
-
-
Barnett, A.1
Brewer, G.J.2
-
4
-
-
79251493453
-
The amazing osteocyte
-
doi:10.1002/jbmr.320
-
Bonewald LF (2011) The amazing osteocyte. J Bone Miner Res 26(2):229-238. doi:10.1002/jbmr.320
-
(2011)
J Bone Miner Res
, vol.26
, Issue.2
, pp. 229-238
-
-
Bonewald, L.F.1
-
5
-
-
77649128750
-
Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis
-
doi:10.1002/art.27305
-
Carames B, Taniguchi N, Otsuki S, Blanco FJ, Lotz M (2010) Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis. Arthritis Rheum 62(3):791-801. doi:10.1002/art.27305
-
(2010)
Arthritis Rheum
, vol.62
, Issue.3
, pp. 791-801
-
-
Carames, B.1
Taniguchi, N.2
Otsuki, S.3
Blanco, F.J.4
Lotz, M.5
-
6
-
-
34548482499
-
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy
-
DOI 10.1074/jbc.M703663200
-
Chan EY, Kir S, Tooze SA (2007) siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy. J Biol Chem 282(35):25464-25474. doi:10.1074/jbc.M703663200 (Pubitemid 47372826)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.35
, pp. 25464-25474
-
-
Chan, E.Y.W.1
Kir, S.2
Tooze, S.A.3
-
7
-
-
79960308079
-
Autophagy deregulation in neurodegenerative diseases: Recent advances and future perspectives
-
doi:10.1111/j.1471-4159.2011.07314.x
-
Cheung ZH, Ip NY (2011) Autophagy deregulation in neurodegenerative diseases: recent advances and future perspectives. J Neurochem 118(3):317-325. doi:10.1111/j.1471-4159.2011.07314.x
-
(2011)
J Neurochem
, vol.118
, Issue.3
, pp. 317-325
-
-
Cheung, Z.H.1
Ip, N.Y.2
-
8
-
-
80052989037
-
Enhanced autophagy from chronic toxicity of iron and mutant A53T alpha-synuclein: Implications for neuronal cell death in Parkinson disease
-
doi:10.1074/jbc.M111.268409
-
Chew KC, Ang ET, Tai YK, Tsang F, Lo SQ, Ong E, Ong WY, Shen HM, Lim KL, Dawson VL, Dawson TM, Soong TW (2011) Enhanced autophagy from chronic toxicity of iron and mutant A53T alpha-synuclein: implications for neuronal cell death in Parkinson disease. J Biol Chem 286(38):33380-33389. doi:10.1074/jbc.M111.268409
-
(2011)
J Biol Chem
, vol.286
, Issue.38
, pp. 33380-33389
-
-
Chew, K.C.1
Ang, E.T.2
Tai, Y.K.3
Tsang, F.4
Lo, S.Q.5
Ong, E.6
Ong, W.Y.7
Shen, H.M.8
Lim, K.L.9
Dawson, V.L.10
Dawson, T.M.11
Soong, T.W.12
-
9
-
-
0014148066
-
Participation of lysosomes in cellular autophagy induced in rat liver by glucagon
-
Deter RL, Baudhuin P, De Duve C (1967) Participation of lysosomes in cellular autophagy induced in rat liver by glucagon. J Cell Biol 35(2):C11-C16
-
(1967)
J Cell Biol
, vol.35
, Issue.2
-
-
Deter, R.L.1
Baudhuin, P.2
De Duve, C.3
-
10
-
-
77950252174
-
Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
-
doi:10.1038/onc.2009.519
-
Djavaheri-Mergny M, Maiuri MC, Kroemer G (2010) Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene 29(12):1717-1719. doi:10.1038/onc.2009.519
-
(2010)
Oncogene
, vol.29
, Issue.12
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
-
11
-
-
39049194057
-
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
-
Furuya N, Yu J, Byfield M, Pattingre S, Levine B (2005) The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1(1):46-52
-
(2005)
Autophagy
, vol.1
, Issue.1
, pp. 46-52
-
-
Furuya, N.1
Yu, J.2
Byfield, M.3
Pattingre, S.4
Levine, B.5
-
12
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
doi:10.1038/nature04724
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441(7095):885-889. doi:10.1038/nature04724
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
Mizushima, N.11
-
13
-
-
84866142024
-
Emerging role of autophagy in kidney function, diseases and aging
-
doi:10.4161/auto.19821
-
Huber TB, Edelstein CL, Hartleben B, Inoki K, Dong Z, Koya D, Kume S, Lieberthal W, Pallet N, Quiroga A, Ravichandran K, Susztak K, Yoshida S (2012) Emerging role of autophagy in kidney function, diseases and aging. Autophagy 8(7):1009-1031. doi:10.4161/auto.19821
-
(2012)
Autophagy
, vol.8
, Issue.7
, pp. 1009-1031
-
-
Huber, T.B.1
Edelstein, C.L.2
Hartleben, B.3
Inoki, K.4
Dong, Z.5
Koya, D.6
Kume, S.7
Lieberthal, W.8
Pallet, N.9
Quiroga, A.10
Ravichandran, K.11
Susztak, K.12
Yoshida, S.13
-
14
-
-
80052382924
-
The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells
-
Isaka Y, Kimura T, Takabatake Y (2011) The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells. Autophagy 7(9):1085-1087
-
(2011)
Autophagy
, vol.7
, Issue.9
, pp. 1085-1087
-
-
Isaka, Y.1
Kimura, T.2
Takabatake, Y.3
-
15
-
-
80053931553
-
Glucocorticoid dose determines osteocyte cell fate
-
doi:10.1096/fj.11-182519
-
Jia J, Yao W, Guan M, Dai W, Shahnazari M, Kar R, Bonewald L, Jiang JX, Lane NE (2011) Glucocorticoid dose determines osteocyte cell fate. FASEB J 25(10):3366-3376. doi:10.1096/fj.11-182519
-
(2011)
FASEB J
, vol.25
, Issue.10
, pp. 3366-3376
-
-
Jia, J.1
Yao, W.2
Guan, M.3
Dai, W.4
Shahnazari, M.5
Kar, R.6
Bonewald, L.7
Jiang, J.X.8
Lane, N.E.9
-
16
-
-
33748642989
-
Spinal cord injury causes more damage to bone mass, bone structure, biomechanical properties and bone metabolism than sciatic neurectomy in young rats
-
doi:10.1007/s00198-006-0165-3
-
Jiang SD, Jiang LS, Dai LY (2006) Spinal cord injury causes more damage to bone mass, bone structure, biomechanical properties and bone metabolism than sciatic neurectomy in young rats. Osteoporos Int 17(10):1552-1561. doi:10.1007/s00198-006-0165-3
-
(2006)
Osteoporos Int
, vol.17
, Issue.10
, pp. 1552-1561
-
-
Jiang, S.D.1
Jiang, L.S.2
Dai, L.Y.3
-
17
-
-
52749094770
-
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
-
doi:10.1016/j.cmet.2008.08.013
-
Jung HS, Chung KW, Won Kim J, Kim J, Komatsu M, Tanaka K, Nguyen YH, Kang TM, Yoon KH, Kim JW, Jeong YT, Han MS, Lee MK, Kim KW, Shin J, Lee MS (2008) Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab 8(4):318-324. doi:10.1016/j.cmet.2008.08.013
-
(2008)
Cell Metab
, vol.8
, Issue.4
, pp. 318-324
-
-
Jung, H.S.1
Chung, K.W.2
Won Kim, J.3
Kim, J.4
Komatsu, M.5
Tanaka, K.6
Nguyen, Y.H.7
Kang, T.M.8
Yoon, K.H.9
Kim, J.W.10
Jeong, Y.T.11
Han, M.S.12
Lee, M.K.13
Kim, K.W.14
Shin, J.15
Lee, M.S.16
-
18
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clave C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Droge W, Dron M, Dunn WA Jr, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fesus L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, Gonzalez-Estevez C, Gorski S, Gottlieb RA, Haussinger D, He YW, Heidenreich K, Hill JA, Hoyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jaattela M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovacs AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, Lopez-Otin C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Melendez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Munz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nurnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Talloczy Z, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcategui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4(2):151-175
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
Bamber, B.A.11
Bassham, D.C.12
Bergamini, E.13
Bi, X.14
Biard-Piechaczyk, M.15
Blum, J.S.16
De Bredesen17
Brodsky, J.L.18
Brumell, J.H.19
Brunk, U.T.20
Bursch, W.21
Camougrand, N.22
Cebollero, E.23
Cecconi, F.24
Chen, Y.25
Chin, L.S.26
Choi, A.27
Chu, C.T.28
Chung, J.29
Clarke, P.G.30
Clark, R.S.31
Clarke, S.G.32
Clave, C.33
Cleveland, J.L.34
Codogno, P.35
Colombo, M.I.36
Coto-Montes, A.37
Cregg, J.M.38
Cuervo, A.M.39
Debnath, J.40
Demarchi, F.41
Dennis, P.B.42
Dennis, P.A.43
Deretic, V.44
Devenish, R.J.45
Di Sano, F.46
Dice, J.F.47
Difiglia, M.48
Dinesh-Kumar, S.49
Distelhorst, C.W.50
Djavaheri-Mergny, M.51
Dorsey, F.C.52
Droge, W.53
Dron, M.54
Dunn Jr., W.A.55
Duszenko, M.56
Eissa, N.T.57
Elazar, Z.58
Esclatine, A.59
Eskelinen, E.L.60
Fesus, L.61
Finley, K.D.62
Fuentes, J.M.63
Fueyo, J.64
Fujisaki, K.65
Galliot, B.66
Gao, F.B.67
Gewirtz, D.A.68
Gibson, S.B.69
Gohla, A.70
Goldberg, A.L.71
Gonzalez, R.72
Gonzalez-Estevez, C.73
Gorski, S.74
Gottlieb, R.A.75
Haussinger, D.76
He, Y.W.77
Heidenreich, K.78
Hill, J.A.79
Hoyer-Hansen, M.80
Hu, X.81
Huang, W.P.82
Iwasaki, A.83
Jaattela, M.84
Jackson, W.T.85
Jiang, X.86
Jin, S.87
Johansen, T.88
Jung, J.U.89
Kadowaki, M.90
Kang, C.91
Kelekar, A.92
Kessel, D.H.93
Kiel, J.A.94
Kim, H.P.95
Kimchi, A.96
Kinsella, T.J.97
Kiselyov, K.98
Kitamoto, K.99
more..
-
19
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
DOI 10.1083/jcb.200412022
-
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T (2005) Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 169(3):425-434. doi:10.1083/jcb.200412022 (Pubitemid 40686693)
-
(2005)
Journal of Cell Biology
, vol.169
, Issue.3
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
20
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
doi:10.1016/j.cell.2007.12.018
-
Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132(1):27-42. doi:10.1016/j.cell.2007.12.018
-
(2008)
Cell
, vol.132
, Issue.1
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
21
-
-
25144506835
-
Autophagy in cell death: An innocent convict?
-
DOI 10.1172/JCI26390
-
Levine B, Yuan J (2005) Autophagy in cell death: an innocent convict? J Clin Investig 115(10):2679-2688. doi:10.1172/jci26390 (Pubitemid 41434392)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
22
-
-
84886819890
-
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation
-
doi:10.1002/jbmr.1971
-
Liu F, Fang F, Yuan H, Yang D, Chen Y, Williams L, Goldstein SA, Krebsbach PH, Guan JL (2013) Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res. doi:10.1002/jbmr.1971
-
(2013)
J Bone Miner Res
-
-
Liu, F.1
Fang, F.2
Yuan, H.3
Yang, D.4
Chen, Y.5
Williams, L.6
Goldstein, S.A.7
Krebsbach, P.H.8
Guan, J.L.9
-
23
-
-
77956420489
-
Can autophagy promote longevity?
-
doi:10.1038/ncb0910-842
-
Madeo F, Tavernarakis N, Kroemer G (2010) Can autophagy promote longevity? Nat Cell Biol 12(9):842-846. doi:10.1038/ncb0910-842
-
(2010)
Nat Cell Biol
, vol.12
, Issue.9
, pp. 842-846
-
-
Madeo, F.1
Tavernarakis, N.2
Kroemer, G.3
-
24
-
-
77953363121
-
What old means to bone
-
doi:10.1016/j.tem.2010.01.010
-
Manolagas SC, Parfitt AM (2010) What old means to bone. Trends Endocrinol Metab 21(6):369-374. doi:10.1016/j.tem.2010.01.010
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.6
, pp. 369-374
-
-
Manolagas, S.C.1
Parfitt, A.M.2
-
25
-
-
77954891467
-
Regulation of placental leptin expression by cyclic adenosine 5'-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways
-
doi:10.1210/en.2010-0064
-
Maymo JL, Perez Perez A, Duenas JL, Calvo JC, Sanchez-Margalet V, Varone CL (2010) Regulation of placental leptin expression by cyclic adenosine 5'-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways. Endocrinology 151(8):3738-3751. doi:10.1210/en.2010-0064
-
(2010)
Endocrinology
, vol.151
, Issue.8
, pp. 3738-3751
-
-
Maymo, J.L.1
Perez Perez, A.2
Duenas, J.L.3
Calvo, J.C.4
Sanchez-Margalet, V.5
Varone, C.L.6
-
26
-
-
38749092637
-
Structural determinants of vertebral fracture risk
-
doi:10.1359/jbmr.070728
-
Melton LJ 3rd, Riggs BL, Keaveny TM, Achenbach SJ, Hoffmann PF, Camp JJ, Rouleau PA, Bouxsein ML, Amin S, Atkinson EJ, Robb RA, Khosla S (2007) Structural determinants of vertebral fracture risk. Journal of Bone and Mineral Research: the official journal of the American Society for Bone and Mineral Research 22(12):1885-1892. doi:10.1359/jbmr.070728
-
(2007)
Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research
, vol.22
, Issue.12
, pp. 1885-1892
-
-
Melton III, L.J.1
Riggs, B.L.2
Keaveny, T.M.3
Achenbach, S.J.4
Hoffmann, P.F.5
Camp, J.J.6
Rouleau, P.A.7
Bouxsein, M.L.8
Amin, S.9
Atkinson, E.J.10
Robb, R.A.11
Khosla, S.12
-
27
-
-
76249127368
-
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo
-
doi:10.1073/pnas.0913170107
-
Mortensen M, Ferguson DJ, Edelmann M, Kessler B, Morten KJ, Komatsu M, Simon AK (2010) Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. Proc Natl Acad Sci USA 107(2):832-837. doi:10.1073/pnas.0913170107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.2
, pp. 832-837
-
-
Mortensen, M.1
Ferguson, D.J.2
Edelmann, M.3
Kessler, B.4
Morten, K.J.5
Komatsu, M.6
Simon, A.K.7
-
28
-
-
34447316414
-
Trends in oxidative aging theories
-
DOI 10.1016/j.freeradbiomed.2007.03.034, PII S0891584907002481
-
Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H (2007) Trends in oxidative aging theories. Free Radical Biol Med 43(4):477-503. doi:10.1016/j.freeradbiomed.2007.03.034 (Pubitemid 47058228)
-
(2007)
Free Radical Biology and Medicine
, vol.43
, Issue.4
, pp. 477-503
-
-
Muller, F.L.1
Lustgarten, M.S.2
Jang, Y.3
Richardson, A.4
Van Remmen, H.5
-
29
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
DOI 10.1038/nm1574, PII NM1574
-
Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, Taniike M, Omiya S, Mizote I, Matsumura Y, Asahi M, Nishida K, Hori M, Mizushima N, Otsu K (2007) The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med 13(5):619-624. doi:10.1038/nm1574 (Pubitemid 46828485)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
Omiya, S.7
Mizote, I.8
Matsumura, Y.9
Asahi, M.10
Nishida, K.11
Hori, M.12
Mizushima, N.13
Otsu, K.14
-
30
-
-
80053938104
-
Evidence for osteocyte regulation of bone homeostasis through RANKL expression
-
doi:10.1038/nm.2452
-
Nakashima T, Hayashi M, Fukunaga T, Kurata K, Oh-Hora M, Feng JQ, Bonewald LF, Kodama T, Wutz A, Wagner EF, Penninger JM, Takayanagi H (2011) Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med 17(10):1231-1234. doi:10.1038/nm.2452
-
(2011)
Nat Med
, vol.17
, Issue.10
, pp. 1231-1234
-
-
Nakashima, T.1
Hayashi, M.2
Fukunaga, T.3
Kurata, K.4
Oh-Hora, M.5
Feng, J.Q.6
Bonewald, L.F.7
Kodama, T.8
Wutz, A.9
Wagner, E.F.10
Penninger, J.M.11
Takayanagi, H.12
-
31
-
-
84879065741
-
Suppression of autophagy in osteocytes mimics skeletal aging
-
doi:10.1074/jbc.M112.444190
-
Onal M, Piemontese M, Xiong J, Wang Y, Han L, Ye S, Komatsu M, Selig M, Weinstein RS, Zhao H, Jilka RL, Almeida M, Manolagas SC, O'Brien CA (2013) Suppression of autophagy in osteocytes mimics skeletal aging. J Biol Chem 288(24):17432-17440. doi:10.1074/jbc.M112.444190
-
(2013)
J Biol Chem
, vol.288
, Issue.24
, pp. 17432-17440
-
-
Onal, M.1
Piemontese, M.2
Xiong, J.3
Wang, Y.4
Han, L.5
Ye, S.6
Komatsu, M.7
Selig, M.8
Weinstein, R.S.9
Zhao, H.10
Jilka, R.L.11
Almeida, M.12
Manolagas, S.C.13
O'Brien, C.A.14
-
32
-
-
35448955695
-
Bone structure and metabolism in a rodent model of male senile osteoporosis
-
DOI 10.1016/j.exger.2007.08.008, PII S053155650700191X
-
Pietschmann P, Skalicky M, Kneissel M, Rauner M, Hofbauer G, Stupphann D, Viidik A (2007) Bone structure and metabolism in a rodent model of male senile osteoporosis. Exp Gerontol 42(11):1099-1108. doi:10.1016/j.exger.2007.08.008 (Pubitemid 47633460)
-
(2007)
Experimental Gerontology
, vol.42
, Issue.11
, pp. 1099-1108
-
-
Pietschmann, P.1
Skalicky, M.2
Kneissel, M.3
Rauner, M.4
Hofbauer, G.5
Stupphann, D.6
Viidik, A.7
-
33
-
-
64249123646
-
Autophagy is essential for mitochondrial clearance in mature T lymphocytes
-
doi:10.4049/jimmunol.0801143
-
Pua HH, Guo J, Komatsu M, He YW (2009) Autophagy is essential for mitochondrial clearance in mature T lymphocytes. Journal of immunology (Baltimore, Md: 1950) 182 (7):4046-4055. doi:10.4049/jimmunol.0801143
-
(2009)
Journal of Immunology (Baltimore, Md: 1950)
, vol.182
, Issue.7
, pp. 4046-4055
-
-
Pua, H.H.1
Guo, J.2
Komatsu, M.3
He, Y.W.4
-
34
-
-
66049133683
-
Aging: Central role for autophagy and the lysosomal degradative system
-
doi:10.1016/j.arr.2009.05.001
-
Rajawat YS, Hilioti Z, Bossis I (2009) Aging: central role for autophagy and the lysosomal degradative system. Ageing Res Rev 8(3):199-213. doi:10.1016/j.arr.2009.05.001
-
(2009)
Ageing Res Rev
, vol.8
, Issue.3
, pp. 199-213
-
-
Rajawat, Y.S.1
Hilioti, Z.2
Bossis, I.3
-
35
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
doi:10.1152/physrev.00030.2009
-
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Moreau K, Narayanan U, Renna M, Siddiqi FH, Underwood BR, Winslow AR, Rubinsztein DC (2010) Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 90(4):1383-1435. doi:10.1152/physrev.00030.2009
-
(2010)
Physiol Rev
, vol.90
, Issue.4
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
Massey, D.C.11
Menzies, F.M.12
Moreau, K.13
Narayanan, U.14
Renna, M.15
Siddiqi, F.H.16
Underwood, B.R.17
Winslow, A.R.18
Rubinsztein, D.C.19
-
36
-
-
38449106930
-
Femoral neck BMD is a strong predictor of hip fracture susceptibility in elderly men and women because it detects cortical bone instability: The Rotterdam Study
-
DOI 10.1359/jbmr.070712
-
Rivadeneira F, Zillikens MC, De Laet CE, Hofman A, Uitterlinden AG, Beck TJ, Pols HA (2007) Femoral neck BMD is a strong predictor of hip fracture susceptibility in elderly men and women because it detects cortical bone instability: the Rotterdam study. J Bone Miner Res 22(11):1781-1790. doi:10.1359/jbmr.070712 (Pubitemid 351235145)
-
(2007)
Journal of Bone and Mineral Research
, vol.22
, Issue.11
, pp. 1781-1790
-
-
Rivadeneira, F.1
Zillikens, M.C.2
De Laet, C.E.D.H.3
Hofman, A.4
Uitterlinden, A.G.5
Beck, T.J.6
Pols, H.A.P.7
-
37
-
-
80052303130
-
Autophagy and aging
-
doi:10.1016/j.cell.2011.07.030
-
Rubinsztein DC, Marino G, Kroemer G (2011) Autophagy and aging. Cell 146(5):682-695. doi:10.1016/j.cell.2011.07.030
-
(2011)
Cell
, vol.146
, Issue.5
, pp. 682-695
-
-
Rubinsztein, D.C.1
Marino, G.2
Kroemer, G.3
-
38
-
-
53549132810
-
Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification
-
doi:10.1101/gad.1711308
-
Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G (2008) Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev 22(19):2645-2650. doi:10.1101/gad.1711308
-
(2008)
Genes Dev
, vol.22
, Issue.19
, pp. 2645-2650
-
-
Settembre, C.1
Arteaga-Solis, E.2
McKee, M.D.3
De Pablo, R.4
Al Awqati, Q.5
Ballabio, A.6
Karsenty, G.7
-
39
-
-
84863259803
-
Excessive autophagy contributes to neuron death in cerebral ischemia
-
doi:10.1111/j.1755-5949.2012.00295.x
-
Shi R, Weng J, Zhao L, Li XM, Gao TM, Kong J (2012) Excessive autophagy contributes to neuron death in cerebral ischemia. CNS Neurosci Ther 18(3):250-260. doi:10.1111/j.1755-5949.2012.00295.x
-
(2012)
CNS Neurosci Ther
, vol.18
, Issue.3
, pp. 250-260
-
-
Shi, R.1
Weng, J.2
Zhao, L.3
Li, X.M.4
Gao, T.M.5
Kong, J.6
-
40
-
-
33744916798
-
Regulation of intracellular accumulation of mutant huntingtin by beclin 1
-
DOI 10.1074/jbc.M600364200
-
Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J (2006) Regulation of intra-cellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem 281(20):14474-14485. doi:10.1074/jbc.M600364200 (Pubitemid 43848378)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.20
, pp. 14474-14485
-
-
Shibata, M.1
Lu, T.2
Furuya, T.3
Degterev, A.4
Mizushima, N.5
Yoshimori, T.6
MacDonald, M.7
Yankner, B.8
Yuan, J.9
-
41
-
-
84859874179
-
Hypoxia induces apoptosis and autophagic cell death in human periodontal ligament cells through HIF-1alpha pathway
-
doi:10.1111/j.1365-2184.2012.00810.x
-
Song ZC, Zhou W, Shu R, Ni J (2012) Hypoxia induces apoptosis and autophagic cell death in human periodontal ligament cells through HIF-1alpha pathway. Cell Prolif 45(3):239-248. doi:10.1111/j.1365-2184.2012.00810.x
-
(2012)
Cell Prolif
, vol.45
, Issue.3
, pp. 239-248
-
-
Song, Z.C.1
Zhou, W.2
Shu, R.3
Ni, J.4
-
42
-
-
73849152107
-
Severity of vertebral fractures is associated with alterations of cortical architecture in postmenopausal women
-
doi:10.1359/jbmr.081223
-
Sornay-Rendu E, Cabrera-Bravo JL, Boutroy S, Munoz F, Delmas PD (2009) Severity of vertebral fractures is associated with alterations of cortical architecture in postmenopausal women. J Bone Miner Res 24(4):737-743. doi:10.1359/jbmr.081223
-
(2009)
J Bone Miner Res
, vol.24
, Issue.4
, pp. 737-743
-
-
Sornay-Rendu, E.1
Cabrera-Bravo, J.L.2
Boutroy, S.3
Munoz, F.4
Delmas, P.D.5
-
43
-
-
78349285075
-
Integrative physiology of the aging bone: Insights from animal and cellular models
-
doi:10.1111/j.1749-6632.2010.05813.x
-
Syed FA, Hoey KA (2010) Integrative physiology of the aging bone: insights from animal and cellular models. Ann N Y Acad Sci 1211:95-106. doi:10.1111/j.1749-6632.2010.05813.x
-
(2010)
Ann N Y Acad Sci
, vol.1211
, pp. 95-106
-
-
Syed, F.A.1
Hoey, K.A.2
-
44
-
-
77955342581
-
Inhibition of autophagy in the heart induces age-related cardiomyopathy
-
doi:10.4161/auto.6.5.11947
-
Taneike M, Yamaguchi O, Nakai A, Hikoso S, Takeda T, Mizote I, Oka T, Tamai T, Oyabu J, Murakawa T, Nishida K, Shimizu T, Hori M, Komuro I, Takuji Shirasawa TS, Mizushima N, Otsu K (2010) Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 6(5):600-606. doi:10.4161/auto.6. 5.11947
-
(2010)
Autophagy
, vol.6
, Issue.5
, pp. 600-606
-
-
Taneike, M.1
Yamaguchi, O.2
Nakai, A.3
Hikoso, S.4
Takeda, T.5
Mizote, I.6
Oka, T.7
Tamai, T.8
Oyabu, J.9
Murakawa, T.10
Nishida, K.11
Shimizu, T.12
Hori, M.13
Komuro, I.14
Takuji Shirasawa, T.S.15
Mizushima, N.16
Otsu, K.17
-
45
-
-
38049115875
-
Apoptosis and autophagy: Regulatory connections between two supposedly different processes
-
doi:10.1007/s10495-007-0154-9
-
Thorburn A (2008) Apoptosis and autophagy: regulatory connections between two supposedly different processes. Apoptosis 13(1):1-9. doi:10.1007/s10495- 007-0154-9
-
(2008)
Apoptosis
, vol.13
, Issue.1
, pp. 1-9
-
-
Thorburn, A.1
-
46
-
-
14844310233
-
Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells
-
DOI 10.1091/mbc.E04-10-0906
-
Thorburn J, Moore F, Rao A, Barclay WW, Thomas LR, Grant KW, Cramer SD, Thorburn A (2005) Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells. Mol Biol Cell 16(3):1189-1199. doi:10.1091/mbc.E04-10-0906 (Pubitemid 40349556)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.3
, pp. 1189-1199
-
-
Thorburn, J.1
Moore, F.2
Rao, A.3
Barclay, W.W.4
Thomas, L.R.5
Grant, K.W.6
Cramer, S.D.7
Thorburn, A.8
-
47
-
-
27644514227
-
Another way to die: Autophagic programmed cell death
-
DOI 10.1038/sj.cdd.4401777, PII 4401777
-
Tsujimoto Y, Shimizu S (2005) Another way to die: autophagic programmed cell death. Cell Death Differ 12(Suppl 2):1528-1534. doi:10.1038/sj.cdd.4401777 (Pubitemid 41553989)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.SUPPL. 2
, pp. 1528-1534
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
48
-
-
57649234905
-
Autophagy genes and ageing
-
doi:10.1038/cdd.2008.126
-
Vellai T (2009) Autophagy genes and ageing. Cell Death Differ 16(1):94-102. doi:10.1038/cdd.2008.126
-
(2009)
Cell Death Differ
, vol.16
, Issue.1
, pp. 94-102
-
-
Vellai, T.1
-
49
-
-
0034901696
-
Male rodent model of age-related bone loss in men
-
DOI 10.1016/S8756-3282(01)00483-5, PII S8756328201004835
-
Wang L, Banu J, McMahan CA, Kalu DN (2001) Male rodent model of age-related bone loss in men. Bone 29(2):141-148 (Pubitemid 32737189)
-
(2001)
Bone
, vol.29
, Issue.2
, pp. 141-148
-
-
Wang, L.1
Banu, J.2
Mcmahan, C.A.3
Kalu, D.N.4
-
50
-
-
75049085555
-
Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise
-
doi:10.1016/j.exger.2009.11.002
-
Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C (2010) Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol 45(2):138-148. doi:10.1016/j.exger.2009.11.002
-
(2010)
Exp Gerontol
, vol.45
, Issue.2
, pp. 138-148
-
-
Wohlgemuth, S.E.1
Seo, A.Y.2
Marzetti, E.3
Lees, H.A.4
Leeuwenburgh, C.5
-
51
-
-
78349253795
-
Glucocorticoid-induced autophagy in osteocytes
-
doi:10.1002/jbmr.160
-
Xia X, Kar R, Gluhak-Heinrich J, Yao W, Lane NE, Bonewald LF, Biswas SK, Lo WK, Jiang JX (2010) Glucocorticoid-induced autophagy in osteocytes. J Bone Miner Res 25(11):2479-2488. doi:10.1002/jbmr.160
-
(2010)
J Bone Miner Res
, vol.25
, Issue.11
, pp. 2479-2488
-
-
Xia, X.1
Kar, R.2
Gluhak-Heinrich, J.3
Yao, W.4
Lane, N.E.5
Bonewald, L.F.6
Biswas, S.K.7
Lo, W.K.8
Jiang, J.X.9
-
52
-
-
80053978532
-
Matrix-embedded cells control osteoclast formation
-
doi:10.1038/nm.2448
-
Xiong J, Onal M, Jilka RL, Weinstein RS, Manolagas SC, O'Brien CA (2011) Matrix-embedded cells control osteoclast formation. Nat Med 17(10):1235-1241. doi:10.1038/nm.2448
-
(2011)
Nat Med
, vol.17
, Issue.10
, pp. 1235-1241
-
-
Xiong, J.1
Onal, M.2
Jilka, R.L.3
Weinstein, R.S.4
Manolagas, S.C.5
O'Brien, C.A.6
-
53
-
-
80755188000
-
Age-related increases of macroautophagy and chaperone-mediated autophagy in rat nucleus pulposus
-
doi:10.3109/03008207.2011.564336
-
Ye W, Xu K, Huang D, Liang A, Peng Y, Zhu W, Li C (2011) Age-related increases of macroautophagy and chaperone-mediated autophagy in rat nucleus pulposus. Connect Tissue Res 52(6):472-478. doi:10.3109/03008207.2011.564336
-
(2011)
Connect Tissue Res
, vol.52
, Issue.6
, pp. 472-478
-
-
Ye, W.1
Xu, K.2
Huang, D.3
Liang, A.4
Peng, Y.5
Zhu, W.6
Li, C.7
-
54
-
-
84872133973
-
Increased macroautophagy in the pathological process of intervertebral disc degeneration in rats
-
doi:10.3109/03008207.2012.715702
-
Ye W, Zhu W, Xu K, Liang A, Peng Y, Huang D, Li C (2013) Increased macroautophagy in the pathological process of intervertebral disc degeneration in rats. Connect Tissue Res 54(1):22-28. doi:10.3109/03008207.2012.715702
-
(2013)
Connect Tissue Res
, vol.54
, Issue.1
, pp. 22-28
-
-
Ye, W.1
Zhu, W.2
Xu, K.3
Liang, A.4
Peng, Y.5
Huang, D.6
Li, C.7
-
55
-
-
80051786264
-
Bone cell autophagy is regulated by environmental factors
-
doi:10.1159/000324647
-
Zahm AM, Bohensky J, Adams CS, Shapiro IM, Srinivas V (2011) Bone cell autophagy is regulated by environmental factors. Cells Tissues Organs 194(2-4):274-278. doi:10.1159/000324647
-
(2011)
Cells Tissues Organs
, vol.194
, Issue.2-4
, pp. 274-278
-
-
Zahm, A.M.1
Bohensky, J.2
Adams, C.S.3
Shapiro, I.M.4
Srinivas, V.5
-
56
-
-
79958198033
-
Involvement of oxidative stress in age-related bone loss
-
doi:10.1016/j.jss.2011.02.033
-
Zhang YB, Zhong ZM, Hou G, Jiang H, Chen JT (2011) Involvement of oxidative stress in age-related bone loss. J Surg Res 169(1):e37-e42. doi:10.1016/j.jss.2011.02.033
-
(2011)
J Surg Res
, vol.169
, Issue.1
-
-
Zhang, Y.B.1
Zhong, Z.M.2
Hou, G.3
Jiang, H.4
Chen, J.T.5
|