Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues

ACS Chemical Biology

Volumn 9, Issue 8, 2014, Pages 1726-1735

  Wang, Yen Chih ^a   Dozier, Jonathan K ^a   Beese, Lorena S ^b   Distefano, Mark D ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE DERIVATIVE; AZIDE; BIOTIN DERIVATIVE; ISOPRENOID PHOSPHATE; PROTEIN FARNESYLTRANSFERASE; STREPTAVIDIN; TETRAPEPTIDE; P21(RAS) FARNESYL-PROTEIN TRANSFERASE; PEPTIDE LIBRARY; TRANSFERASE;

ARTICLE; CANDIDA ALBICANS; CARBOXY TERMINAL SEQUENCE; CLICK CHEMISTRY; ENZYME MECHANISM; ENZYME SPECIFICITY; NONHUMAN; PEPTIDE LIBRARY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN FARNESYLATION; PROTEIN PROCESSING; RATTUS NORVEGICUS; SACCHAROMYCES CEREVISIAE; SOLID PHASE SYNTHESIS; ANIMAL; CHEMISTRY; METABOLISM; RAT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; PEPTIDE LIBRARY; POLYISOPRENYL PHOSPHATES; RATS; SUBSTRATE SPECIFICITY;

EID: 84906249918     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb5002312     Document Type: Article

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