Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 27, 2013, Pages 11085-11090

  Charron, Guillaume ^a   Li, Melody M H ^a   MacDonald, Margaret R ^a   Hang, Howard C ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Antiviral effector; Bioorthogonal labeling; Click chemistry; Lipid chemical reporter; Protein prenylation

Indexed keywords

PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER ANTIVIRAL PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; HOST RESISTANCE; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PRENYLATION; PROTEOMICS; S FARNESYLATION; VIRUS INFECTION;

ANTIVIRAL EFFECTOR; BIOORTHOGONAL LABELING; CLICK CHEMISTRY; LIPID CHEMICAL REPORTER; PROTEIN PRENYLATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; HEK293 CELLS; HELA CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTRACELLULAR MEMBRANES; LIPOPROTEINS; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; PRENYLATION; PROTEIN ISOFORMS; PROTEIN PRENYLATION; RATS; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VIRUS DISEASES;

EUKARYOTA;

EID: 84879730573     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302564110     Document Type: Article

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