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Angewandte Chemie - International Edition

Volumn 53, Issue 11, 2014, Pages 2931-2934

Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4′-dimethylsulfinylbenzhydryl

(6) Dekan, Zoltan a Mobli, Mehdi a Pennington, Michael W b Fung, Eileen c Nemeth, Elizabeta c Alewood, Paul F a

a UNIVERSITY OF QUEENSLAND (Australia)

b Peptides International Inc (United States)

c UNIVERSITY OF CALIFORNIA (United States)

Author keywords

disulfide bonds; hepcidin; peptides; protecting groups; regioselective folding

Indexed keywords

CONFORMATIONAL HETEROGENEITY; DISULFIDE BONDS; HEPCIDIN; PROTECTING GROUP; REGIO-SELECTIVE; REGIOSELECTIVE SYNTHESIS; SYNTHETIC STRATEGIES; TOTAL SYNTHESIS;

AMINO ACIDS; COVALENT BONDS; PEPTIDES;

REGIOSELECTIVITY;

BENZHYDRYL DERIVATIVE; CYSTEINE; DISULFIDE; HEPCIDIN; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DISULFIDE BONDS; HUMAN; MOLECULAR GENETICS; PROTECTING GROUPS; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REGIOSELECTIVE FOLDING; STEREOISOMERISM; SYNTHESIS;

DISULFIDE BONDS; HEPCIDIN; PEPTIDES; PROTECTING GROUPS; REGIOSELECTIVE FOLDING;

AMINO ACID SEQUENCE; BENZHYDRYL COMPOUNDS; CYSTEINE; DISULFIDES; HEPCIDINS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STEREOISOMERISM;

EID: 84896793374 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201310103 Document Type: Article

Times cited : (42)

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