메뉴 건너뛰기




Volumn 94, Issue 2, 1998, Pages 175-184

Protein prenyl transferase activities of Plasmodium falciparum

Author keywords

Farnesyl transferase; Geranylgeranyl transferase; Plasmodium falciparum; Protein prenylation; Schizont; Trophozoite

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; DIMETHYLALLYLTRANSFERASE; L 745631; UNCLASSIFIED DRUG;

EID: 0032145868     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00065-6     Document Type: Article
Times cited : (114)

References (51)
  • 3
    • 0025375466 scopus 로고
    • Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini
    • Yamane HK, Farnsworth CC, Xie H et al. Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini. Proc Natl Acad Sci USA. 87:1990;5868-5872.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5868-5872
    • Yamane, H.K.1    Farnsworth, C.C.2    Xie, H.3
  • 5
    • 0026726050 scopus 로고
    • Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
    • Inglese J, Koch WJ, Caron MG, Lefkowitz RJ Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. Nature. 359:1992;147-150.
    • (1992) Nature , vol.359 , pp. 147-150
    • Inglese, J.1    Koch, W.J.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 6
    • 0023604660 scopus 로고
    • Isoprenylated proteins in cultured cells: Subcellular distribution and changes related to altered morphology and growth arrest induced by mevalonate deprivation
    • Maltese WA, Sheridan KM Isoprenylated proteins in cultured cells: Subcellular distribution and changes related to altered morphology and growth arrest induced by mevalonate deprivation. J Cell Physiol. 133:1987;471-481.
    • (1987) J Cell Physiol , vol.133 , pp. 471-481
    • Maltese, W.A.1    Sheridan, K.M.2
  • 7
    • 0021799463 scopus 로고
    • Defective macromolecule biosynthesis and cell-cycle progression in a mammalian cell starved for mevalonate
    • Sinensky M, Logel JH Defective macromolecule biosynthesis and cell-cycle progression in a mammalian cell starved for mevalonate. Proc Natl Acad Sci USA. 82:1985;3257-3261.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 3257-3261
    • Sinensky, M.1    Logel, J.H.2
  • 8
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS Regulation of the mevalonate pathway. Nature. 343:1990;425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 10
    • 0024316475 scopus 로고
    • Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans
    • Schafer WR, Kim R, Sterne R, Thorner J, Kim S-H, Rine J Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans. Science. 245:1989;379-385.
    • (1989) Science , vol.245 , pp. 379-385
    • Schafer, W.R.1    Kim, R.2    Sterne, R.3    Thorner, J.4    Kim S-H5    Rine, J.6
  • 11
    • 0025359577 scopus 로고
    • Common modifications of trimeric G proteins and ras protein: Involvement of polyisoprenylation
    • Finegold AA, Schafer WR, Rine J, Whiteway M, Tamanoi F Common modifications of trimeric G proteins and ras protein: Involvement of polyisoprenylation. Science. 249:1990;165-169.
    • (1990) Science , vol.249 , pp. 165-169
    • Finegold, A.A.1    Schafer, W.R.2    Rine, J.3    Whiteway, M.4    Tamanoi, F.5
  • 12
    • 0025032490 scopus 로고
    • Post-translational modification of low molecular mass GTP-binding proteins by isoprenoid
    • Maltese WA, Sheridan KM, Repko EM, Erdman RA Post-translational modification of low molecular mass GTP-binding proteins by isoprenoid. J Biol Chem. 265:1990;2148-2155.
    • (1990) J Biol Chem , vol.265 , pp. 2148-2155
    • Maltese, W.A.1    Sheridan, K.M.2    Repko, E.M.3    Erdman, R.A.4
  • 15
    • 0024406286 scopus 로고
    • All ras proteins are polyisoprenylated but only some are palmitoylated
    • Hancock JF, Magee AI, Childs JE, Marshall CJ All ras proteins are polyisoprenylated but only some are palmitoylated. Cell. 57:1989;1167-1177.
    • (1989) Cell , vol.57 , pp. 1167-1177
    • Hancock, J.F.1    Magee, A.I.2    Childs, J.E.3    Marshall, C.J.4
  • 16
    • 0029898894 scopus 로고    scopus 로고
    • Protein prenylation: Molecular mechanisms and functional consequence
    • Zhang FL, Casey PJ Protein prenylation: Molecular mechanisms and functional consequence. Annu Rev Biochem. 65:1996;241-269.
    • (1996) Annu Rev Biochem , vol.65 , pp. 241-269
    • Zhang, F.L.1    Casey, P.J.2
  • 17
    • 0026353346 scopus 로고
    • Sequence dependence of protein isoprenylation
    • Moores SL, Schaber MD, Mosser SD et al. Sequence dependence of protein isoprenylation. J Biol Chem. 266:1991;14603-14610.
    • (1991) J Biol Chem , vol.266 , pp. 14603-14610
    • Moores, S.L.1    Schaber, M.D.2    Mosser, S.D.3
  • 19
    • 0025179232 scopus 로고
    • Polyisoprenylation of ras in vitro by a farnesyl-protein transferase
    • Schaber MD, O'Hara MB, Garsky VM et al. Polyisoprenylation of ras in vitro by a farnesyl-protein transferase. J Biol Chem. 265:1990;14701-14704.
    • (1990) J Biol Chem , vol.265 , pp. 14701-14704
    • Schaber, M.D.1    O'Hara, M.B.2    Garsky, V.M.3
  • 20
    • 0025018023 scopus 로고
    • Identification and preliminary characterization of protein-cysteine farnesyl transferase
    • Manne V, Roberts D, Tobin A et al. Identification and preliminary characterization of protein-cysteine farnesyl transferase. Proc Natl Acad Sci USA. 87:1990;7541-7545.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7541-7545
    • Manne, V.1    Roberts, D.2    Tobin, A.3
  • 21
    • 0025829655 scopus 로고
    • Protein geranylgeranyl transferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product
    • Finegold AA, Johnson DI, Farnsworth CC et al. Protein geranylgeranyl transferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product. Proc Natl Acad Sci USA. 88:1991;4448-4452.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4448-4452
    • Finegold, A.A.1    Johnson, D.I.2    Farnsworth, C.C.3
  • 22
    • 0025819073 scopus 로고
    • Protein farnesyl transferase and geranylgeranyl transferase share a common α-subunit
    • Seabra MC, Reiss Y, Casey PJ, Brown MS, Goldstein JL Protein farnesyl transferase and geranylgeranyl transferase share a common α-subunit. Cell. 65:1991;429-434.
    • (1991) Cell , vol.65 , pp. 429-434
    • Seabra, M.C.1    Reiss, Y.2    Casey, P.J.3    Brown, M.S.4    Goldstein, J.L.5
  • 23
    • 0026001936 scopus 로고
    • A protein geranylgeranyl transferase from bovine brain: Implications for protein prenylation specificity
    • Yokoyama K, Goodwin GW, Ghomashchi F, Glomset JA, Gelb MH A protein geranylgeranyl transferase from bovine brain: Implications for protein prenylation specificity. Proc Natl Acad Sci USA. 88:1991;5302-5306.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5302-5306
    • Yokoyama, K.1    Goodwin, G.W.2    Ghomashchi, F.3    Glomset, J.A.4    Gelb, M.H.5
  • 24
    • 0026072339 scopus 로고
    • Enzymatic modification of proteins with a geranylgeranyl isoprenoid
    • Casey PJ, Thissen JA, Moomaw JF Enzymatic modification of proteins with a geranylgeranyl isoprenoid. Proc Natl Acad Sci USA. 88:1991;8631-8635.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8631-8635
    • Casey, P.J.1    Thissen, J.A.2    Moomaw, J.F.3
  • 25
    • 0026056618 scopus 로고
    • A novel prenyl transferase for a small GTP-binding protein having a C-terminal Cys-Ala-Cys structure
    • Horiuchi H, Kawata M, Katayama M et al. A novel prenyl transferase for a small GTP-binding protein having a C-terminal Cys-Ala-Cys structure. J Biol Chem. 266:1991;16981-16984.
    • (1991) J Biol Chem , vol.266 , pp. 16981-16984
    • Horiuchi, H.1    Kawata, M.2    Katayama, M.3
  • 27
    • 0027154011 scopus 로고
    • Characterization of mevalonate-labeled lipids isolated from parasite proteins in Schistosoma mansoni
    • Chen G-Z, Bennett JL Characterization of mevalonate-labeled lipids isolated from parasite proteins in Schistosoma mansoni. Mol Biochem Parasitol. 59:1993;287-292.
    • (1993) Mol Biochem Parasitol , vol.59 , pp. 287-292
    • Chen G-Z1    Bennett, J.L.2
  • 28
    • 0030581643 scopus 로고    scopus 로고
    • Characterisation of protein isoprenylation in procyclic form Trypanosoma brucei
    • Field H, Blench I, Croft S, Field MC Characterisation of protein isoprenylation in procyclic form Trypanosoma brucei. Mol Biochem Parasitol. 82:1996;67-80.
    • (1996) Mol Biochem Parasitol , vol.82 , pp. 67-80
    • Field, H.1    Blench, I.2    Croft, S.3    Field, M.C.4
  • 30
    • 0010438154 scopus 로고
    • Physiological role of HMGCoA reductase in regulating egg production by Schistosoma mansoni
    • Van de Was EA, Mills G, Chen GZ, Bennett JL Physiological role of HMGCoA reductase in regulating egg production by Schistosoma mansoni. Am J Physiol. 255:1989;618-625.
    • (1989) Am J Physiol , vol.255 , pp. 618-625
    • Van De Was, E.A.1    Mills, G.2    Chen, G.Z.3    Bennett, J.L.4
  • 31
    • 0026196266 scopus 로고
    • Purification and characterization of 3-hydroxymethylglutaryl-coenzyme A reductase of Schistosoma mansoni: Regulation of parasite enzyme activity differs from mammalian host Ny-Schmied
    • Chen GZ, Foster L, Bennett JL Purification and characterization of 3-hydroxymethylglutaryl-coenzyme A reductase of Schistosoma mansoni: Regulation of parasite enzyme activity differs from mammalian host Ny-Schmied. Arch Pharmacol. 73:1991;82-92.
    • (1991) Arch Pharmacol , vol.73 , pp. 82-92
    • Chen, G.Z.1    Foster, L.2    Bennett, J.L.3
  • 32
    • 0029112114 scopus 로고
    • Changes in protein prenylation and prenyl transferase activity in the rat seminiferous epithelium during early stages of spermatogenesis
    • Dugan JM, Allen CM Changes in protein prenylation and prenyl transferase activity in the rat seminiferous epithelium during early stages of spermatogenesis. Biol Reprod. 53:1995;958-973.
    • (1995) Biol Reprod , vol.53 , pp. 958-973
    • Dugan, J.M.1    Allen, C.M.2
  • 33
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • Trager WT, Jensen JB Human malaria parasites in continuous culture. Science. 193:1976;673-675.
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.T.1    Jensen, J.B.2
  • 34
    • 0018704491 scopus 로고
    • Synchronization of Plasmodium falciparum erythrocytic stages in culture
    • Lambros C, Vanderberg JP Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol. 65:1979;418-420.
    • (1979) J Parasitol , vol.65 , pp. 418-420
    • Lambros, C.1    Vanderberg, J.P.2
  • 35
    • 0000731846 scopus 로고
    • Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with α-difluoromethyl ornithine cure murine malaria
    • Bitonti AJ, Dumont JA, Bush TL et al. Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with α-difluoromethyl ornithine cure murine malaria. Proc Natl Acad Sci USA. 86:1989;651-655.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 651-655
    • Bitonti, A.J.1    Dumont, J.A.2    Bush, T.L.3
  • 36
    • 0029986149 scopus 로고    scopus 로고
    • 2-Substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyl transferase
    • Williams TM, Ciccarone TM, MacTough SC et al. 2-Substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyl transferase. J Med Chem. 39:1996;1345-1348.
    • (1996) J Med Chem , vol.39 , pp. 1345-1348
    • Williams, T.M.1    Ciccarone, T.M.2    MacTough, S.C.3
  • 37
    • 0028967646 scopus 로고
    • Ras farnesylation as a target for novel antitumor agents: Potent and selective farnesyl diphosphate analog inhibitors of farnesyl transferase
    • Manne V, Ricca CS, Brown JG et al. Ras farnesylation as a target for novel antitumor agents: Potent and selective farnesyl diphosphate analog inhibitors of farnesyl transferase. Drug Dev Res. 34:1995;121-137.
    • (1995) Drug Dev Res , vol.34 , pp. 121-137
    • Manne, V.1    Ricca, C.S.2    Brown, J.G.3
  • 40
    • 0027413551 scopus 로고
    • Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo
    • Gibbs JB, Pompliano DL, Mosser SD et al. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. J Biol Chem. 268:1993;7617-7620.
    • (1993) J Biol Chem , vol.268 , pp. 7617-7620
    • Gibbs, J.B.1    Pompliano, D.L.2    Mosser, S.D.3
  • 41
    • 0025550273 scopus 로고
    • Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria
    • Mbaya B, Rigomier D, Edorh GG, Karst F, Schrevel J Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria. Biochem Biophys Res Commun. 173:1990;849-854.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 849-854
    • Mbaya, B.1    Rigomier, D.2    Edorh, G.G.3    Karst, F.4    Schrevel, J.5
  • 42
    • 0021211920 scopus 로고
    • A reevaluation of the status of cholesterol in erythrocytes infected by Plasmodium knowlesi and P. falciparum
    • Vial HJ, Philippot JR, Wallach DFH A reevaluation of the status of cholesterol in erythrocytes infected by Plasmodium knowlesi and P. falciparum. Mol Biochem Parsitol. 13:1984;53-65.
    • (1984) Mol Biochem Parsitol , vol.13 , pp. 53-65
    • Vial, H.J.1    Philippot, J.R.2    Wallach, D.F.H.3
  • 43
    • 0028211246 scopus 로고
    • Pseudopeptide inhibitors of ras farnesyl-protein transferase
    • Graham SL, deSolms SJ, Giuliani EA et al. Pseudopeptide inhibitors of ras farnesyl-protein transferase. J Med Chem. 37:1994;725-732.
    • (1994) J Med Chem , vol.37 , pp. 725-732
    • Graham, S.L.1    Desolms, S.J.2    Giuliani, E.A.3
  • 44
    • 0029150669 scopus 로고
    • Inhibition of farnesyl transferase induces regression of mammary and salivary carcinomas in ras transgenic mice
    • Kohl NE, Omer CA, Conner MW et al. Inhibition of farnesyl transferase induces regression of mammary and salivary carcinomas in ras transgenic mice. Nature Med. 1:1995;792-797.
    • (1995) Nature Med , vol.1 , pp. 792-797
    • Kohl, N.E.1    Omer, C.A.2    Conner, M.W.3
  • 45
    • 0030249050 scopus 로고    scopus 로고
    • Identification of a family of rab G-proteins in Plasmodium falciparum and a detailed characterisation of pf rab6
    • deCastro FA, Ward GE, Jambou R et al. Identification of a family of rab G-proteins in Plasmodium falciparum and a detailed characterisation of pf rab6. Mol Biochem Parasitol. 80:1996;77-88.
    • (1996) Mol Biochem Parasitol , vol.80 , pp. 77-88
    • Decastro, F.A.1    Ward, G.E.2    Jambou, R.3
  • 46
    • 0030566712 scopus 로고    scopus 로고
    • Identification and localization of rab6 in malaria parasites: Separation from ERD2 and implications for an 'unstacked' Golgi
    • Van-Wye J, Ghori N, Webster P, Mitschler RR, Elmendorf HG, Haldar K Identification and localization of rab6 in malaria parasites: separation from ERD2 and implications for an 'unstacked' Golgi. Mol Biochem Parasitol. 83:1996;107-120.
    • (1996) Mol Biochem Parasitol , vol.83 , pp. 107-120
    • Van-Wye, J.1    Ghori, N.2    Webster, P.3    Mitschler, R.R.4    Elmendorf, H.G.5    Haldar, K.6
  • 47
    • 0030199154 scopus 로고    scopus 로고
    • Plasmodium falciparum: The small GTPase rab11
    • Langsley G, Chakrabarti D Plasmodium falciparum: The small GTPase rab11. Expr Parasitol. 83:1996;250-251.
    • (1996) Expr Parasitol , vol.83 , pp. 250-251
    • Langsley, G.1    Chakrabarti, D.2
  • 48
    • 0027416643 scopus 로고
    • Purification of a mammalian protein geranylgeranyl transferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex
    • Yokoyama KI, Gelb MH Purification of a mammalian protein geranylgeranyl transferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex. J Biol Chem. 268:1993;4055-4060.
    • (1993) J Biol Chem , vol.268 , pp. 4055-4060
    • Yokoyama, K.I.1    Gelb, M.H.2
  • 50
    • 0029126757 scopus 로고
    • Burkitt lymphoma Daudi cells contain two distinct farnesyl transferases with different divalent cation requirements
    • Vogt A, Sun J, Qian Y, Tan-Chiu E, Hamilton AD, Sebti SM Burkitt lymphoma Daudi cells contain two distinct farnesyl transferases with different divalent cation requirements. Biochemistry. 34:1995;12398-12403.
    • (1995) Biochemistry , vol.34 , pp. 12398-12403
    • Vogt, A.1    Sun, J.2    Qian, Y.3    Tan-Chiu, E.4    Hamilton, A.D.5    Sebti, S.M.6
  • 51
    • 0027323459 scopus 로고
    • Benzodiazepine peptidomimetics: Potent inhibitors of ras farnesylation in animal cells
    • James GL, Goldstein JL, Brown MS et al. Benzodiazepine peptidomimetics: Potent inhibitors of ras farnesylation in animal cells. Science. 260:1993;1937-1942.
    • (1993) Science , vol.260 , pp. 1937-1942
    • James, G.L.1    Goldstein, J.L.2    Brown, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.