Cell biology of sarcomeric protein engineering: Disease modeling and therapeutic potential

Anatomical Record

Volumn 297, Issue 9, 2014, Pages 1663-1669

  Thompson, Brian R ^a   Metzger, Joseph M ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Acute genetic engineering; Adult cardiac myocytes; Calcium sensitivity; Molecular dynamics; Myofilament, troponin; Sarcomere

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MUTANT PROTEIN; MYOSIN HEAVY CHAIN BETA; SHORT HAIRPIN RNA; TROPONIN I; MUSCLE PROTEIN;

ARTICLE; CYTOLOGY; DISEASE MODEL; GENE MUTATION; GENE TRANSFER; GENETIC ENGINEERING; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOFLUORESCENCE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RESTRICTIVE CARDIOMYOPATHY; STATIC ELECTRICITY; THIN FILAMENT; TURNOVER TIME; WESTERN BLOTTING; ANIMAL; GENE THERAPY; GENETIC PREDISPOSITION; GENETICS; HEART DISEASES; HEART MUSCLE; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN ENGINEERING; SARCOMERE;

ANIMALS; GENETIC PREDISPOSITION TO DISEASE; GENETIC THERAPY; HEART DISEASES; HUMANS; MUSCLE PROTEINS; MUTATION; MYOCARDIUM; PHENOTYPE; PROTEIN ENGINEERING; SARCOMERES;

EID: 84906100578     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.22966     Document Type: Article

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