Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations

Physiological Genomics

Volumn 42, Issue 2, 2010, Pages 287-299

  Palpant, Nathan J ^a   Houang, Evelyne M ^b   Delport, Wayne ^c   Hastings, Kenneth E M ^d   Onufriev, Alexey V ^e   Sham, Yuk Y ^b   Metzger, Joseph M ^a  

^a University of Minnesota   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Amphibian; Histidine; Mammal; Myofilament; Single nucleotide polymorphism

Indexed keywords

ALANINE; CALCIUM; HISTIDINE; PEPTIDE; TROPONIN; TROPONIN I;

ARTICLE; CHORDATA; DNA MODIFICATION; ELECTRICITY; EVOLUTIONARY ADAPTATION; GENE MUTATION; GENETIC POLYMORPHISM; HEART PERFORMANCE; MAMMAL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MYOFILAMENT; NONHUMAN; PHYLOGENETIC TREE; PHYLOGENY; PRIORITY JOURNAL; SIMULATION; THERMODYNAMICS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR EVOLUTION; MUTATION;

ANIMALS; CALCIUM; CHORDATA; EVOLUTION, MOLECULAR; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; PEPTIDES; PHYLOGENY; TROPONIN; TROPONIN I;

AMPHIBIA; CHORDATA; MAMMALIA;

EID: 77955438444     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00033.2010     Document Type: Article

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