Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy

Science

Volumn 342, Issue 6154, 2013, Pages 111-114

  Jiang, Jianming ^a,c,d   Wakimoto, Hiroko ^a,b,c   Seidman, J G ^a   Seidman, Christine E ^a,c,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN HEAVY CHAIN; PARVOVIRUS VECTOR;

ALLELE; GENE EXPRESSION; GENETIC ANALYSIS; INHIBITION; MUTATION; PATHOLOGY; PROTEIN; RODENT;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ECHOCARDIOGRAPHY; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HYPERTROPHIC CARDIOMYOPATHY; MOUSE; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; RNA INTERFERENCE; VIRAL GENE DELIVERY SYSTEM;

ADENO-ASSOCIATED VIRUS; MUS;

EID: 84885676191     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1236921     Document Type: Article

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