A revised method of troponin exchange in permeabilised cardiac trabeculae using vanadate: Functional consequences of a HCM-causing mutation in troponin I

Journal of Muscle Research and Cell Motility

Volumn 27, Issue 8, 2006, Pages 585-590

  Preston, Laura C ^a   Watkins, Hugh ^a   Redwood, Charles S ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Calcium sensitivity; Hypertrophic cardiomyopathy; Skinned fibres; Troponin I

Indexed keywords

PROTEIN SUBUNIT; TROPONIN C; TROPONIN I; VANADIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GUINEA PIG; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOBLOTTING; MUTATIONAL ANALYSIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

ANIMALS; CARDIOMYOPATHY, HYPERTROPHIC; GUINEA PIGS; HUMANS; MUTATION; MYOCARDIUM; TROPONIN I; VANADATES;

CAVIA PORCELLUS;

EID: 33750588346     PISSN: 01424319     EISSN: 15732657     Source Type: Journal    
DOI: 10.1007/s10974-006-9079-0     Document Type: Article

References (21)

1. Allhouse LD, Potter JD, Ashley CC (1999) A novel method of extraction of TnC from skeletal muscle myofibrils. Pflugers Arch 437:695-701
2. Arner A, Strauss JD, Svensson C, Ruegg JC (1995) Effects of troponin-I extraction with vanadate and of the calcium sensitizer EMD 53998 on the rate of force generation in skinned cardiac muscle. J Mol Cell Cardiol 27:615-623
3. Brenner B, Kraft T, Yu LC, Chalovich JM (1999) Thin filament activation probed by fluorescence of N-((2-(iodoacetoxy)ethyl)-N-methyl)amino-7-nitrobenz- 2-oxa-1,3-diazole-labeled troponin I incorporated into skinned fibers of rabbit psoas muscle. Biophys J 77:2677-2691
4. Burton D, Abdulrazzak H, Knott A, Elliott K, Redwood C, Watkins H, Marston S, Ashley C (2002) Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility. Biochem J 362:443-451
5. Deng Y, Schmidtmann A, Kruse S, Filatov V, Heilmeyer LM Jr, Jaquet K, Thieleczek R (2003) Phosphorylation of human cardiac troponin I G203S and K206Q linked to familial hypertrophic cardiomyopathy affects actomyosin interaction in different ways. J Mol Cell Cardiol 35:1365-1374
6. Hatakenaka M, Ohtsuki I (1991) Replacement of three troponin components with cardiac troponin components within single glycerinated skeletal muscle fibers. Biochem Biophys Res Commun 181:1022-1027
7. Hernandez OM, Housmans PR, Potter JD (2001) Invited review: pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation. J Appl Physiol 90:1125-1136
8. Kimura A, et al (1997) Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat Genet 16:379-382
9. Knollmann BC, Potter JD (2001) Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy. Trends Cardiovasc Med 11:206-212
10. Köhler J, Chen Y, Brenner B, Gordon AM, Kraft T, Martyn DA, Regnier M, Rivera AJ, Wang CK, Chase PB (2003) Familial hypertrophic cardiomyopathy mutations in troponin I (K183Δ, G203S, K206Q) enhance filament sliding. Physiol Genomics 14:117-128
11. Robinson P, Mirza M, Knott A, Abdulrazzak H, Willott R, Marston S, Watkins H, Redwood C (2002) Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy. J Biol Chem 277:40710-40716
12. Seidman JG, Seidman C (2001) The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms. Cell 104:557-567
13. She M, Trimble D, Yu LC, Chalovich JM (2000) Factors contributing to troponin exchange in myofibrils and in solution. J Muscle Res Cell Motil 21:737-745
14. Squire JM, Morris EP (1998) A new look at thin filament regulation in vertebrate skeletal muscle. FASEB J 12:761-771
15. Strauss JD, Zeugner C, Van Eyk JE, Bletz C, Troschka M, Ruegg JC (1992) Troponin replacement in permeabilized cardiac muscle. Reversible extraction of troponin I by incubation with vanadate. FEBS Lett 310:229-234
16. Strauss JD, Van Eyk JE, Barth Z, Kluwe L, Wiesner RJ, Maeda K, Ruegg JC (1996) Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle. Pflugers Arch 431:853-862
17. Szczesna D, Zhang R, Zhao J, Jones M, Guzman G, Potter JD (2000) Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy. J Biol Chem 275:624-630
18. Takahashi-Yanaga F, et al (2001) Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy. J Mol Cell Cardiol 33:2095-2107
19. Tobacman LS (1996) Thin filament-mediated regulation of cardiac contraction. Annu Rev Physiol 58:447-481
20. Van Eyk JE, Strauss JD, Hodges RS, Ruegg JC (1993) A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. FEBS Lett 323:223-228
21. Vibert P, Craig R, Lehman W (1997) Steric-model for activation of muscle thin filaments. J Mol Biol 266:8-14