Age-related loss of SirT1 expression results in dysregulated human vascular smooth muscle cell function

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 307, Issue 4, 2014, Pages

  Thompson, Anne Marie ^a   Wagner, Robert ^a   Rzucidlo, Eva M ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Aging; Human smooth muscle cells; Senescence; Sirtuin; Vasculature

Indexed keywords

SIRTUIN 1; SIRT1 PROTEIN, HUMAN;

AGED; AGING; APOPTOSIS; ARTICLE; CELL AGING; CELL FUNCTION; CELL ISOLATION; CELL LEVEL; CELL MIGRATION; CELL PROLIFERATION; CELL STRESS; CELLULAR STRESS RESPONSE; CHILD; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SCHOOL CHILD; SMOOTH MUSCLE FIBER; TISSUE SECTION; VASCULAR SMOOTH MUSCLE; VERY ELDERLY; WESTERN BLOTTING; ADOLESCENT; ADULT; AGE; CELL CULTURE; CELL MOTION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CELL AGING; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHILD; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; SIRTUIN 1;

EID: 84906074653     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00871.2013     Document Type: Article

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