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Volumn 10, Issue 9, 2014, Pages 1151-1164

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: Dendritic cells as potential targets

Author keywords

apoptosis; autoimmunity; clearance deficiency; dendritic cells; IFN signature; NETosis; secondary necrosis; systemic lupus erythematosus; tolerance; toll like receptor

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; AUTOANTIGEN; DEOXYRIBONUCLEASE I; HYDROXYCHLOROQUINE; TOLL LIKE RECEPTOR;

EID: 84906069844     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2014.944162     Document Type: Review
Times cited : (69)

References (98)
  • 1
    • 0028844576 scopus 로고
    • Phototherapy
    • Abel EA. Phototherapy. Dermatol Clin 1995;13(4):841-9
    • (1995) Dermatol Clin , vol.13 , Issue.4 , pp. 841-849
    • Abel, E.A.1
  • 2
    • 0031454570 scopus 로고    scopus 로고
    • Immunosuppressive effects of apoptotic cells
    • Voll RE, Herrmann M, Roth EA, et al. Immunosuppressive effects of apoptotic cells. Nature 1997;390(6658):350-1
    • (1997) Nature , vol.390 , Issue.6658 , pp. 350-351
    • Voll, R.E.1    Herrmann, M.2    Roth, E.A.3
  • 3
    • 77951971046 scopus 로고    scopus 로고
    • The role of defective clearance of apoptotic cells in systemic autoimmunity
    • Munoz LE, Lauber K, Schiller M, et al. The role of defective clearance of apoptotic cells in systemic autoimmunity. Nat Rev Rheumatol 2010;6(5):280-9
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.5 , pp. 280-289
    • Munoz, L.E.1    Lauber, K.2    Schiller, M.3
  • 4
    • 84874210171 scopus 로고    scopus 로고
    • Review: Apoptotic mechanisms in bacterial infections of the central nervous system
    • Parthasarathy G, Philipp MT. Review: apoptotic mechanisms in bacterial infections of the central nervous system. Front Immunol 2012;3:306
    • (2012) Front Immunol , vol.3 , pp. 306
    • Parthasarathy, G.1    Philipp, M.T.2
  • 5
    • 84906051479 scopus 로고    scopus 로고
    • Loading of nuclear autoantigens prototypically recognized by SLE sera into late apoptotic vesicles requires intact microtubules and MLCK activity
    • [Epub ahead of print]
    • Zirngibl M, Furnrohr BG, Janko C, et al. Loading of nuclear autoantigens prototypically recognized by SLE sera into late apoptotic vesicles requires intact microtubules and MLCK activity. Clin Exp Immunol 2014. [Epub ahead of print]
    • (2014) Clin Exp Immunol
    • Zirngibl, M.1    Furnrohr, B.G.2    Janko, C.3
  • 6
    • 77952484769 scopus 로고    scopus 로고
    • The role of incomplete clearance of apoptotic cells in the etiology and pathogenesis of SLE
    • 154-6
    • Munoz LE, Lauber K, Schiller M, et al. [The role of incomplete clearance of apoptotic cells in the etiology and pathogenesis of SLE]. Z Rheumatol 2010; 69(2):152 154-6
    • (2010) Z Rheumatol , vol.69 , Issue.2 , pp. 152
    • Munoz, L.E.1    Lauber, K.2    Schiller, M.3
  • 7
    • 77956913114 scopus 로고    scopus 로고
    • Dangerous attraction: Phagocyte recruitment and danger signals of apoptotic and necrotic cells
    • Peter C, Wesselborg S, Herrmann M, Lauber K. Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells. Apoptosis 2010;15(9): 1007-28
    • (2010) Apoptosis , vol.15 , Issue.9 , pp. 1007-1028
    • Peter, C.1    Wesselborg, S.2    Herrmann, M.3    Lauber, K.4
  • 8
    • 78649981811 scopus 로고    scopus 로고
    • Cell death in the neighbourhood: Direct microenvironmental effects of apoptosis in normal and neoplastic tissues
    • Gregory CD, Pound JD. Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues. J Pathol 2011;223(2):177-94
    • (2011) J Pathol , vol.223 , Issue.2 , pp. 177-194
    • Gregory, C.D.1    Pound, J.D.2
  • 9
    • 0034073163 scopus 로고    scopus 로고
    • Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6
    • Ishimoto Y, Ohashi K, Mizuno K, Nakano T. Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6. J Biochem 2000;127(3):411-17
    • (2000) J Biochem , vol.127 , Issue.3 , pp. 411-417
    • Ishimoto, Y.1    Ohashi, K.2    Mizuno, K.3    Nakano, T.4
  • 10
    • 84891452023 scopus 로고    scopus 로고
    • Cooperative binding of Annexin A5 to phosphatidylserine on apoptotic cell membranes
    • Janko C, Jeremic I, Biermann M, et al. Cooperative binding of Annexin A5 to phosphatidylserine on apoptotic cell membranes. Phys Biol 2013;10(6):065006
    • (2013) Phys Biol , vol.10 , Issue.6 , pp. 065006
    • Janko, C.1    Jeremic, I.2    Biermann, M.3
  • 11
    • 84891477246 scopus 로고    scopus 로고
    • Surface code - Biophysical signals for apoptotic cell clearance
    • Biermann M, Maueroder C, Brauner JM, et al. Surface code - biophysical signals for apoptotic cell clearance. Phys Biol 2013; 10(6):065007
    • (2013) Phys Biol , vol.10 , Issue.6 , pp. 065007
    • Biermann, M.1    Maueroder, C.2    Brauner, J.M.3
  • 12
    • 77956931638 scopus 로고    scopus 로고
    • Inefficient clearance of dying cells in patients with SLE: Anti-dsDNA autoantibodies MFG-E8 HMGB-1 and other players
    • Kruse K, Janko C, Urbonaviciute V, et al. Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players. Apoptosis 2010;15(9):1098-113
    • (2010) Apoptosis , vol.15 , Issue.9 , pp. 1098-1113
    • Kruse, K.1    Janko, C.2    Urbonaviciute, V.3
  • 13
    • 44449102749 scopus 로고    scopus 로고
    • Apoptotic cells protect mice against lipopolysaccharide-induced shock
    • Ren Y, Xie Y, Jiang G, et al. Apoptotic cells protect mice against lipopolysaccharide-induced shock. J Immunol 2008;180(7):4978-85
    • (2008) J Immunol , vol.180 , Issue.7 , pp. 4978-4985
    • Ren, Y.1    Xie, Y.2    Jiang, G.3
  • 14
    • 84861440668 scopus 로고    scopus 로고
    • 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance
    • Uderhardt S, Herrmann M, Oskolkova OV, et al. 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance. Immunity 2012; 36(5):834-46
    • (2012) Immunity , vol.36 , Issue.5 , pp. 834-846
    • Uderhardt, S.1    Herrmann, M.2    Oskolkova, O.V.3
  • 15
    • 84861368068 scopus 로고    scopus 로고
    • The evolution of the danger theory. Interview by Lauren Constable, Commissioning Editor
    • Matzinger P. The evolution of the danger theory. Interview by Lauren Constable, Commissioning Editor. Expert Rev Clin Immunol 2012;8(4):311-17
    • (2012) Expert Rev Clin Immunol , vol.8 , Issue.4 , pp. 311-317
    • Matzinger, P.1
  • 17
    • 77951251430 scopus 로고    scopus 로고
    • Necroptosis as an alternative form of programmed cell death
    • Christofferson DE, Yuan J. Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol 2010;22(2): 263-8
    • (2010) Curr Opin Cell Biol , vol.22 , Issue.2 , pp. 263-268
    • Christofferson, D.E.1    Yuan, J.2
  • 18
    • 67649526000 scopus 로고    scopus 로고
    • Poly (ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos
    • Wang Y, Dawson VL, Dawson TM. Poly (ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos. Exp Neurol 2009;218(2):193-202
    • (2009) Exp Neurol , vol.218 , Issue.2 , pp. 193-202
    • Wang, Y.1    Dawson, V.L.2    Dawson, T.M.3
  • 19
    • 84861541814 scopus 로고    scopus 로고
    • Ferroptosis: An iron-dependent form of nonapoptotic cell death
    • Dixon SJ, Lemberg KM, Lamprecht MR, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 2012; 149(5):1060-72
    • (2012) Cell , vol.149 , Issue.5 , pp. 1060-1072
    • Dixon, S.J.1    Lemberg, K.M.2    Lamprecht, M.R.3
  • 20
    • 84874280285 scopus 로고    scopus 로고
    • Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells
    • Schorn C, Janko C, Latzko M, et al. Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells. Front Immunol 2012;3:277
    • (2012) Front Immunol , vol.3 , pp. 277
    • Schorn, C.1    Janko, C.2    Latzko, M.3
  • 21
    • 0031838606 scopus 로고    scopus 로고
    • Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus
    • Herrmann M, Voll RE, Zoller OM, et al. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998;41(7): 1241-50
    • (1998) Arthritis Rheum , vol.41 , Issue.7 , pp. 1241-1250
    • Herrmann, M.1    Voll, R.E.2    Zoller, O.M.3
  • 22
    • 0036164008 scopus 로고    scopus 로고
    • Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus
    • Baumann I, Kolowos W, Voll RE, et al. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. Arthritis Rheum 2002;46(1): 191-201
    • (2002) Arthritis Rheum , vol.46 , Issue.1 , pp. 191-201
    • Baumann, I.1    Kolowos, W.2    Voll, R.E.3
  • 23
    • 66449089455 scopus 로고    scopus 로고
    • Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus
    • Munoz LE, Janko C, Grossmayer GE, et al. Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus. Arthritis Rheum 2009;60(6): 1733-42
    • (2009) Arthritis Rheum , vol.60 , Issue.6 , pp. 1733-1742
    • Munoz, L.E.1    Janko, C.2    Grossmayer, G.E.3
  • 24
    • 84880366296 scopus 로고    scopus 로고
    • Colourful death: Six-parameter classification of cell death by flow cytometry - Dead cells tell tales
    • Munoz LE, Maueroder C, Chaurio R, et al. Colourful death: six-parameter classification of cell death by flow cytometry - dead cells tell tales. Autoimmunity 2013;46(5):336-41
    • (2013) Autoimmunity , vol.46 , Issue.5 , pp. 336-341
    • Munoz, L.E.1    Maueroder, C.2    Chaurio, R.3
  • 25
    • 84926023700 scopus 로고    scopus 로고
    • Navigation to the graveyard-induction of various pathways of necrosis and their classification by flow cytometry
    • Janko C, Munoz L, Chaurio R, et al. Navigation to the graveyard-induction of various pathways of necrosis and their classification by flow cytometry. Methods Mol Biol 2013;1004:3-15
    • (2013) Methods Mol Biol , vol.1004 , pp. 3-15
    • Janko, C.1    Munoz, L.2    Chaurio, R.3
  • 26
    • 84900859409 scopus 로고    scopus 로고
    • Breaking immunological tolerance in systemic lupus erythematosus
    • Pieterse E, van der Vlag J. Breaking immunological tolerance in systemic lupus erythematosus. Front Immunol 2014;5:164
    • (2014) Front Immunol , vol.5 , pp. 164
    • Pieterse, E.1    Van Der Vlag, J.2
  • 27
    • 24144501267 scopus 로고    scopus 로고
    • SLE - A disease of clearance deficiency?
    • Munoz LE, Gaipl US, Franz S, et al. SLE - a disease of clearance deficiency? Rheumatology (Oxford) 2005;44(9):1101-7
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.9 , pp. 1101-1107
    • Munoz, L.E.1    Gaipl, U.S.2    Franz, S.3
  • 28
    • 0035837323 scopus 로고    scopus 로고
    • Phagocytosis and clearance of apoptotic cells is mediated by MER
    • Scott RS, McMahon EJ, Pop SM, et al. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 2001; 411(6834):207-11
    • (2001) Nature , vol.411 , Issue.6834 , pp. 207-211
    • Scott, R.S.1    McMahon, E.J.2    Pop, S.M.3
  • 29
    • 0036645294 scopus 로고    scopus 로고
    • Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
    • Cohen PL, Caricchio R, Abraham V, et al. Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J Exp Med 2002;196(1):135-40
    • (2002) J Exp Med , vol.196 , Issue.1 , pp. 135-140
    • Cohen, P.L.1    Caricchio, R.2    Abraham, V.3
  • 30
    • 1042290326 scopus 로고    scopus 로고
    • Cooperation between C1q and DNase i in the clearance of necrotic cell-derived chromatin
    • Gaipl US, Beyer TD, Heyder P, et al. Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin. Arthritis Rheum 2004;50(2): 640-9
    • (2004) Arthritis Rheum , vol.50 , Issue.2 , pp. 640-649
    • Gaipl, U.S.1    Beyer, T.D.2    Heyder, P.3
  • 31
    • 0035042308 scopus 로고    scopus 로고
    • Complement binding is an early feature of necrotic and a rather late event during apoptotic cell death
    • Gaipl US, Kuenkele S, Voll RE, et al. Complement binding is an early feature of necrotic and a rather late event during apoptotic cell death. Cell Death Differ 2001;8(4):327-34
    • (2001) Cell Death Differ , vol.8 , Issue.4 , pp. 327-334
    • Gaipl, U.S.1    Kuenkele, S.2    Voll, R.E.3
  • 32
    • 70349769369 scopus 로고    scopus 로고
    • C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: A novel link between C1q deficiency and systemic lupus erythematosus pathogenesis
    • Lood C, Gullstrand B, Truedsson L, et al. C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis. Arthritis Rheum 2009;60(10): 3081-90
    • (2009) Arthritis Rheum , vol.60 , Issue.10 , pp. 3081-3090
    • Lood, C.1    Gullstrand, B.2    Truedsson, L.3
  • 33
    • 47049116653 scopus 로고    scopus 로고
    • The classical and regulatory functions of C1q in immunity and autoimmunity
    • Lu JH, Teh BK, Wang L, et al. The classical and regulatory functions of C1q in immunity and autoimmunity. Cell Mol Immunol 2008;5(1):9-21
    • (2008) Cell Mol Immunol , vol.5 , Issue.1 , pp. 9-21
    • Lu, J.H.1    Teh, B.K.2    Wang, L.3
  • 34
    • 51149085208 scopus 로고    scopus 로고
    • Nature and functions of autoantibodies
    • Elkon K, Casali P. Nature and functions of autoantibodies. Nat Clin Pract Rheumatol 2008;4(9):491-8
    • (2008) Nat Clin Pract Rheumatol , vol.4 , Issue.9 , pp. 491-498
    • Elkon, K.1    Casali, P.2
  • 35
    • 12344327400 scopus 로고    scopus 로고
    • Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro
    • Quartier P, Potter PK, Ehrenstein MR, et al. Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro. Eur J Immunol 2005;35(1):252-60
    • (2005) Eur J Immunol , vol.35 , Issue.1 , pp. 252-260
    • Quartier, P.1    Potter, P.K.2    Ehrenstein, M.R.3
  • 36
    • 23844468114 scopus 로고    scopus 로고
    • Human serum IgM glycosylation: Identification of glycoforms that can bind to mannan-binding lectin
    • Arnold JN, Wormald MR, Suter DM, et al. Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin. J Biol Chem 2005; 280(32):29080-7
    • (2005) J Biol Chem , vol.280 , Issue.32 , pp. 29080-29087
    • Arnold, J.N.1    Wormald, M.R.2    Suter, D.M.3
  • 37
    • 0023506183 scopus 로고
    • Development of selective IgM deficiency in systemic lupus erythematosus patients with disease of long duration
    • Saiki O, Saeki Y, Tanaka T, et al. Development of selective IgM deficiency in systemic lupus erythematosus patients with disease of long duration. Arthritis Rheum 1987;30(11):1289-92
    • (1987) Arthritis Rheum , vol.30 , Issue.11 , pp. 1289-1292
    • Saiki, O.1    Saeki, Y.2    Tanaka, T.3
  • 38
    • 0034599499 scopus 로고    scopus 로고
    • Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies
    • Ehrenstein MR, Cook HT, Neuberger MS. Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies. J Exp Med 2000;191(7): 1253-8
    • (2000) J Exp Med , vol.191 , Issue.7 , pp. 1253-1258
    • Ehrenstein, M.R.1    Cook, H.T.2    Neuberger, M.S.3
  • 39
    • 34249826624 scopus 로고    scopus 로고
    • Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice
    • Jiang C, Foley J, Clayton N, et al. Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice. J Immunol 2007;178(11): 7422-31
    • (2007) J Immunol , vol.178 , Issue.11 , pp. 7422-7431
    • Jiang, C.1    Foley, J.2    Clayton, N.3
  • 40
    • 0033961425 scopus 로고    scopus 로고
    • Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM
    • Boes M, Schmidt T, Linkemann K, et al. Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM. Proc Natl Acad Sci USA 2000;97(3):1184-9
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.3 , pp. 1184-1189
    • Boes, M.1    Schmidt, T.2    Linkemann, K.3
  • 41
    • 49349092339 scopus 로고    scopus 로고
    • IgM antibodies against dsDNA in SLE
    • Witte T. IgM antibodies against dsDNA in SLE. Clin Rev Allergy Immunol 2008; 34(3):345-7
    • (2008) Clin Rev Allergy Immunol , vol.34 , Issue.3 , pp. 345-347
    • Witte, T.1
  • 42
    • 79953692402 scopus 로고    scopus 로고
    • Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis
    • Jiang C, Zhao ML, Scearce RM, Diaz M. Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis. Arthritis Rheum 2011;63(4):1086-96
    • (2011) Arthritis Rheum , vol.63 , Issue.4 , pp. 1086-1096
    • Jiang, C.1    Zhao, M.L.2    Scearce, R.M.3    Diaz, M.4
  • 43
    • 79955045667 scopus 로고    scopus 로고
    • Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells
    • Notley CA, Brown MA, Wright GP, Ehrenstein MR. Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells. J Immunol 2011;186(8): 4967-72
    • (2011) J Immunol , vol.186 , Issue.8 , pp. 4967-4972
    • Notley, C.A.1    Brown, M.A.2    Wright, G.P.3    Ehrenstein, M.R.4
  • 44
    • 84867947601 scopus 로고    scopus 로고
    • Immunity and autoimmunity to dsDNA and chromatin - The role of immunogenic DNA-binding proteins and nuclease deficiencies
    • Rekvig OP, Mortensen ES. Immunity and autoimmunity to dsDNA and chromatin - the role of immunogenic DNA-binding proteins and nuclease deficiencies. Autoimmunity 2012;45(8):588-92
    • (2012) Autoimmunity , vol.45 , Issue.8 , pp. 588-592
    • Rekvig, O.P.1    Mortensen, E.S.2
  • 45
    • 84887059952 scopus 로고    scopus 로고
    • Lupus nephritis: Enigmas, conflicting models and an emerging concept
    • Seredkina N, Van Der Vlag J, Berden J, et al. Lupus nephritis: enigmas, conflicting models and an emerging concept. Mol Med 2013;19:161-9
    • (2013) Mol Med , vol.19 , pp. 161-169
    • Seredkina, N.1    Van Der Vlag, J.2    Berden, J.3
  • 46
    • 84862156841 scopus 로고    scopus 로고
    • Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens
    • Jog NR, Frisoni L, Shi Q, et al. Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens. Arthritis Rheum 2012;64(4): 1247-56
    • (2012) Arthritis Rheum , vol.64 , Issue.4 , pp. 1247-1256
    • Jog, N.R.1    Frisoni, L.2    Shi, Q.3
  • 47
    • 84902968079 scopus 로고    scopus 로고
    • Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines
    • Schauer C, Janko C, Munoz LE, et al. Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines. Nat Med 2014;20(5): 511-17
    • (2014) Nat Med , vol.20 , Issue.5 , pp. 511-517
    • Schauer, C.1    Janko, C.2    Munoz, L.E.3
  • 48
    • 84905643664 scopus 로고    scopus 로고
    • Acetylated histones contribute to the immunostimulatory potential of Neutrophil Extracellular Traps in Systemic Lupus Erythematosus
    • [Epub ahead of print]
    • Pieterse E, Hofstra J, Berden J, et al. Acetylated histones contribute to the immunostimulatory potential of Neutrophil Extracellular Traps in Systemic Lupus Erythematosus. Clin Exp Immunol 2014. [Epub ahead of print]
    • (2014) Clin Exp Immunol
    • Pieterse, E.1    Hofstra, J.2    Berden, J.3
  • 49
    • 77953088427 scopus 로고    scopus 로고
    • Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
    • Hakkim A, Furnrohr BG, Amann K, et al. Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc Natl Acad Sci USA 2010; 107(21):9813-18
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.21 , pp. 9813-9818
    • Hakkim, A.1    Furnrohr, B.G.2    Amann, K.3
  • 50
    • 84874224361 scopus 로고    scopus 로고
    • Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals
    • Schorn C, Janko C, Krenn V, et al. Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals. Front Immunol 2012;3:376
    • (2012) Front Immunol , vol.3 , pp. 376
    • Schorn, C.1    Janko, C.2    Krenn, V.3
  • 51
    • 74449091545 scopus 로고    scopus 로고
    • Understanding the epidemiology and progression of systemic lupus erythematosus
    • Pons-Estel GJ, Alarcon GS, Scofield L, et al. Understanding the epidemiology and progression of systemic lupus erythematosus. Semin Arthritis Rheum 2010;39(4):257-68
    • (2010) Semin Arthritis Rheum , vol.39 , Issue.4 , pp. 257-268
    • Pons-Estel, G.J.1    Alarcon, G.S.2    Scofield, L.3
  • 52
    • 44849120407 scopus 로고    scopus 로고
    • Apoptosis in the pathogenesis of systemic lupus erythematosus
    • Munoz LE, van Bavel C, Franz S, et al. Apoptosis in the pathogenesis of systemic lupus erythematosus. Lupus 2008;17(5): 371-5
    • (2008) Lupus , vol.17 , Issue.5 , pp. 371-375
    • Munoz, L.E.1    Van Bavel, C.2    Franz, S.3
  • 53
    • 84870013809 scopus 로고    scopus 로고
    • Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus
    • Sarter K, Janko C, Andre S, et al. Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus. Glycobiology 2013;23(1): 12-22
    • (2013) Glycobiology , vol.23 , Issue.1 , pp. 12-22
    • Sarter, K.1    Janko, C.2    Andre, S.3
  • 54
    • 0037215912 scopus 로고    scopus 로고
    • Exposure of anionic phospholipids serves as anti-inflammatory and immunosuppressive signal - Implications for antiphospholipid syndrome and systemic lupus erythematosus
    • Gaipl US, Beyer TD, Baumann I, et al. Exposure of anionic phospholipids serves as anti-inflammatory and immunosuppressive signal - implications for antiphospholipid syndrome and systemic lupus erythematosus. Immunobiology 2003;207(1):73-81
    • (2003) Immunobiology , vol.207 , Issue.1 , pp. 73-81
    • Gaipl, U.S.1    Beyer, T.D.2    Baumann, I.3
  • 55
    • 78149360607 scopus 로고    scopus 로고
    • Autoimmunity and chronic inflammation - Two clearance-related steps in the etiopathogenesis of SLE
    • Munoz LE, Janko C, Schulze C, et al. Autoimmunity and chronic inflammation - two clearance-related steps in the etiopathogenesis of SLE. Autoimmun Rev 2010;10(1):38-42
    • (2010) Autoimmun Rev , vol.10 , Issue.1 , pp. 38-42
    • Munoz, L.E.1    Janko, C.2    Schulze, C.3
  • 56
    • 84873666705 scopus 로고    scopus 로고
    • The role of somatic hypermutation in the generation of pathogenic antibodies in SLE
    • Schroeder K, Herrmann M, Winkler TH. The role of somatic hypermutation in the generation of pathogenic antibodies in SLE. Autoimmunity 2013;46(2):121-7
    • (2013) Autoimmunity , vol.46 , Issue.2 , pp. 121-127
    • Schroeder, K.1    Herrmann, M.2    Winkler, T.H.3
  • 57
    • 77951450176 scopus 로고    scopus 로고
    • IgG opsonized nuclear remnants from dead cells cause systemic inflammation in SLE
    • Munoz LE, Janko C, Chaurio RA, et al. IgG opsonized nuclear remnants from dead cells cause systemic inflammation in SLE. Autoimmunity 2010;43(3):232-5
    • (2010) Autoimmunity , vol.43 , Issue.3 , pp. 232-235
    • Munoz, L.E.1    Janko, C.2    Chaurio, R.A.3
  • 58
    • 33644924588 scopus 로고    scopus 로고
    • Involvement of phosphatidylserine, alphavbeta3, CD14, CD36, and complement C1q in the phagocytosis of primary necrotic lymphocytes by macrophages
    • Bottcher A, Gaipl US, Furnrohr BG, et al. Involvement of phosphatidylserine, alphavbeta3, CD14, CD36, and complement C1q in the phagocytosis of primary necrotic lymphocytes by macrophages. Arthritis Rheum 2006;54(3): 927-38
    • (2006) Arthritis Rheum , vol.54 , Issue.3 , pp. 927-938
    • Bottcher, A.1    Gaipl, U.S.2    Furnrohr, B.G.3
  • 59
    • 77957012651 scopus 로고    scopus 로고
    • The role of dendritic cells in the pathogenesis of systemic lupus erythematosus
    • Fransen JH, van der Vlag J, Ruben J, et al. The role of dendritic cells in the pathogenesis of systemic lupus erythematosus. Arthritis Res Ther 2010; 12(2):207
    • (2010) Arthritis Res Ther , vol.12 , Issue.2 , pp. 207
    • Fransen, J.H.1    Van Der Vlag, J.2    Ruben, J.3
  • 60
    • 39049088951 scopus 로고    scopus 로고
    • Dendritic cells and cytokines in human inflammatory and autoimmune diseases
    • Blanco P, Palucka AK, Pascual V, Banchereau J. Dendritic cells and cytokines in human inflammatory and autoimmune diseases. Cytokine Growth Factor Rev 2008; 19(1):41-52
    • (2008) Cytokine Growth Factor Rev , vol.19 , Issue.1 , pp. 41-52
    • Blanco, P.1    Palucka, A.K.2    Pascual, V.3    Banchereau, J.4
  • 61
    • 63449108301 scopus 로고    scopus 로고
    • Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
    • Ohnmacht C, Pullner A, King SB, et al. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med 2009;206(3):549-59
    • (2009) J Exp Med , vol.206 , Issue.3 , pp. 549-559
    • Ohnmacht, C.1    Pullner, A.2    King, S.B.3
  • 62
    • 34248340997 scopus 로고    scopus 로고
    • Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity
    • Chen M, Huang L, Wang J. Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. Blood 2007;109(10):4360-7
    • (2007) Blood , vol.109 , Issue.10 , pp. 4360-4367
    • Chen, M.1    Huang, L.2    Wang, J.3
  • 63
    • 65749108032 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in the skin: To sense or not to sense nucleic acids
    • Conrad C, Meller S, Gilliet M. Plasmacytoid dendritic cells in the skin: to sense or not to sense nucleic acids. Semin Immunol 2009;21(3):101-9
    • (2009) Semin Immunol , vol.21 , Issue.3 , pp. 101-109
    • Conrad, C.1    Meller, S.2    Gilliet, M.3
  • 64
    • 77952510795 scopus 로고    scopus 로고
    • Dendritic cells in systemic lupus erythematosus
    • Seitz HM, Matsushima GK. Dendritic cells in systemic lupus erythematosus. Int Rev Immunol 2010;29(2):184-209
    • (2010) Int Rev Immunol , vol.29 , Issue.2 , pp. 184-209
    • Seitz, H.M.1    Matsushima, G.K.2
  • 66
    • 77955545859 scopus 로고    scopus 로고
    • The interferon-alpha signature of systemic lupus erythematosus
    • Obermoser G, Pascual V. The interferon-alpha signature of systemic lupus erythematosus. Lupus 2010;19(9):1012-19
    • (2010) Lupus , vol.19 , Issue.9 , pp. 1012-1019
    • Obermoser, G.1    Pascual, V.2
  • 67
    • 2642528779 scopus 로고    scopus 로고
    • Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
    • Lovgren T, Eloranta ML, Bave U, et al. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 2004;50(6):1861-72
    • (2004) Arthritis Rheum , vol.50 , Issue.6 , pp. 1861-1872
    • Lovgren, T.1    Eloranta, M.L.2    Bave, U.3
  • 68
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • Ganguly D, Chamilos G, Lande R, et al. Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J Exp Med 2009;206(9): 1983-94
    • (2009) J Exp Med , vol.206 , Issue.9 , pp. 1983-1994
    • Ganguly, D.1    Chamilos, G.2    Lande, R.3
  • 69
    • 84878257992 scopus 로고    scopus 로고
    • The good the bad and the ugly - TFH cells in human health and disease
    • Tangye SG, Ma CS, Brink R, Deenick EK. The good, the bad and the ugly - TFH cells in human health and disease. Nat Rev Immunol 2013;13(6):412-26
    • (2013) Nat Rev Immunol , vol.13 , Issue.6 , pp. 412-426
    • Tangye, S.G.1    Ma, C.S.2    Brink, R.3    Deenick, E.K.4
  • 70
    • 0032209520 scopus 로고    scopus 로고
    • Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function
    • Rovere P, Vallinoto C, Bondanza A, et al. Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function. J Immunol 1998;161(9):4467-71
    • (1998) J Immunol , vol.161 , Issue.9 , pp. 4467-4471
    • Rovere, P.1    Vallinoto, C.2    Bondanza, A.3
  • 71
    • 8644274867 scopus 로고    scopus 로고
    • Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo
    • Bondanza A, Zimmermann VS, Rovere-Querini P, et al. Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo. J Exp Med 2004;200(9): 1157-65
    • (2004) J Exp Med , vol.200 , Issue.9 , pp. 1157-1165
    • Bondanza, A.1    Zimmermann, V.S.2    Rovere-Querini, P.3
  • 72
    • 59649126956 scopus 로고    scopus 로고
    • Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: Implications for the pathogenesis of SLE
    • Urbonaviciute V, Furnrohr BG, Meister S, et al. Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE. J Exp Med 2008;205(13):3007-18
    • (2008) J Exp Med , vol.205 , Issue.13 , pp. 3007-3018
    • Urbonaviciute, V.1    Furnrohr, B.G.2    Meister, S.3
  • 73
    • 68049091014 scopus 로고    scopus 로고
    • Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17
    • Fransen JH, Hilbrands LB, Ruben J, et al. Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17. Arthritis Rheum 2009;60(8): 2304-13
    • (2009) Arthritis Rheum , vol.60 , Issue.8 , pp. 2304-2313
    • Fransen, J.H.1    Hilbrands, L.B.2    Ruben, J.3
  • 74
    • 34447523785 scopus 로고    scopus 로고
    • Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus
    • Dieker JW, Fransen JH, van Bavel CC, et al. Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus. Arthritis Rheum 2007;56(6):1921-33
    • (2007) Arthritis Rheum , vol.56 , Issue.6 , pp. 1921-1933
    • Dieker, J.W.1    Fransen, J.H.2    Van Bavel, C.C.3
  • 75
    • 0037222972 scopus 로고    scopus 로고
    • Cutting edge: Dissociation between autoimmune response and clinical disease after vaccination with dendritic cells
    • Bondanza A, Zimmermann VS, Dell'Antonio G, et al. Cutting edge: dissociation between autoimmune response and clinical disease after vaccination with dendritic cells. J Immunol 2003;170(1):24-7
    • (2003) J Immunol , vol.170 , Issue.1 , pp. 24-27
    • Bondanza, A.1    Zimmermann, V.S.2    Dell'Antonio, G.3
  • 76
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert ML, Sauter B, Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 1998;392(6671):86-9
    • (1998) Nature , vol.392 , Issue.6671 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 77
    • 84873714715 scopus 로고    scopus 로고
    • Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE
    • Fehr EM, Spoerl S, Heyder P, et al. Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE. J Autoimmun 2013;40:86-95
    • (2013) J Autoimmun , vol.40 , pp. 86-95
    • Fehr, E.M.1    Spoerl, S.2    Heyder, P.3
  • 78
    • 34247236200 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
    • Tian J, Avalos AM, Mao SY, et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol 2007;8(5):487-96
    • (2007) Nat Immunol , vol.8 , Issue.5 , pp. 487-496
    • Tian, J.1    Avalos, A.M.2    Mao, S.Y.3
  • 79
    • 3042548183 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent and - Independent dendritic cell activation by chromatin-immunoglobulin G complexes
    • Boule MW, Broughton C, Mackay F, et al. Toll-like receptor 9-dependent and - independent dendritic cell activation by chromatin-immunoglobulin G complexes. J Exp Med 2004;199(12):1631-40
    • (2004) J Exp Med , vol.199 , Issue.12 , pp. 1631-1640
    • Boule, M.W.1    Broughton, C.2    Mackay, F.3
  • 80
    • 33750953650 scopus 로고    scopus 로고
    • Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: Implications for the induction and maintenance of the autoimmune process
    • Papadimitraki ED, Choulaki C, Koutala E, et al. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum 2006;54(11):3601-11
    • (2006) Arthritis Rheum , vol.54 , Issue.11 , pp. 3601-3611
    • Papadimitraki, E.D.1    Choulaki, C.2    Koutala, E.3
  • 81
    • 65549124475 scopus 로고    scopus 로고
    • Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus
    • Jacob CO, Zhu J, Armstrong DL, et al. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci USA 2009;106(15):6256-61
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.15 , pp. 6256-6261
    • Jacob, C.O.1    Zhu, J.2    Armstrong, D.L.3
  • 82
    • 34248512211 scopus 로고    scopus 로고
    • Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice
    • Sadanaga A, Nakashima H, Akahoshi M, et al. Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice. Arthritis Rheum 2007;56(5):1618-28
    • (2007) Arthritis Rheum , vol.56 , Issue.5 , pp. 1618-1628
    • Sadanaga, A.1    Nakashima, H.2    Akahoshi, M.3
  • 83
    • 33745168605 scopus 로고    scopus 로고
    • Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
    • Pisitkun P, Deane JA, Difilippantonio MJ, et al. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 2006;312(5780): 1669-72
    • (2006) Science , vol.312 , Issue.5780 , pp. 1669-1672
    • Pisitkun, P.1    Deane, J.A.2    Difilippantonio, M.J.3
  • 84
    • 36048962438 scopus 로고    scopus 로고
    • Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • Deane JA, Pisitkun P, Barrett RS, et al. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 2007; 27(5):801-10
    • (2007) Immunity , vol.27 , Issue.5 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3
  • 85
    • 22944490869 scopus 로고    scopus 로고
    • Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
    • Christensen SR, Kashgarian M, Alexopoulou L, et al. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med 2005;202(2):321-31
    • (2005) J Exp Med , vol.202 , Issue.2 , pp. 321-331
    • Christensen, S.R.1    Kashgarian, M.2    Alexopoulou, L.3
  • 86
    • 67749135880 scopus 로고    scopus 로고
    • Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
    • Kono DH, Haraldsson MK, Lawson BR, et al. Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus. Proc Natl Acad Sci USA 2009;106(29):12061-6
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.29 , pp. 12061-12066
    • Kono, D.H.1    Haraldsson, M.K.2    Lawson, B.R.3
  • 87
    • 33748472865 scopus 로고    scopus 로고
    • Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
    • Christensen SR, Shupe J, Nickerson K, et al. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 2006; 25(3):417-28
    • (2006) Immunity , vol.25 , Issue.3 , pp. 417-428
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3
  • 88
    • 31044440025 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling protects against murine lupus
    • Wu X, Peng SL. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum 2006;54(1):336-42
    • (2006) Arthritis Rheum , vol.54 , Issue.1 , pp. 336-342
    • Wu, X.1    Peng, S.L.2
  • 89
    • 34249915031 scopus 로고    scopus 로고
    • Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus
    • Pawar RD, Ramanjaneyulu A, Kulkarni OP, et al. Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus. J Am Soc Nephrol 2007;18(6):1721-31
    • (2007) J Am Soc Nephrol , vol.18 , Issue.6 , pp. 1721-1731
    • Pawar, R.D.1    Ramanjaneyulu, A.2    Kulkarni, O.P.3
  • 90
    • 60549110710 scopus 로고    scopus 로고
    • Oligodeoxyribonucleotide-based antagonists for Toll-like receptors 7 and 9
    • Wang D, Bhagat L, Yu D, et al. Oligodeoxyribonucleotide-based antagonists for Toll-like receptors 7 and 9. J Med Chem 2009;52(2):551-8
    • (2009) J Med Chem , vol.52 , Issue.2 , pp. 551-558
    • Wang, D.1    Bhagat, L.2    Yu, D.3
  • 91
    • 84878597916 scopus 로고    scopus 로고
    • Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus
    • Urbonaviciute V, Starke C, Pirschel W, et al. Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus. Arthritis Rheum 2013;65(6):1612-23
    • (2013) Arthritis Rheum , vol.65 , Issue.6 , pp. 1612-1623
    • Urbonaviciute, V.1    Starke, C.2    Pirschel, W.3
  • 92
    • 34249707811 scopus 로고    scopus 로고
    • TLR-dependent and TLR-independent pathways of type i interferon induction in systemic autoimmunity
    • Baccala R, Hoebe K, Kono DH, et al. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat Med 2007; 13(5):543-51
    • (2007) Nat Med , vol.13 , Issue.5 , pp. 543-551
    • Baccala, R.1    Hoebe, K.2    Kono, D.H.3
  • 93
    • 80053562466 scopus 로고    scopus 로고
    • Safety profile and clinical activity of sifalimumab, a fully human anti-interferon alpha monoclonal antibody, in systemic lupus erythematosus: A phase I, multicentre, double-blind randomised study
    • Merrill JT, Wallace DJ, Petri M, et al. Safety profile and clinical activity of sifalimumab, a fully human anti-interferon alpha monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Ann Rheum Dis 2011;70(11):1905-13
    • (2011) Ann Rheum Dis , vol.70 , Issue.11 , pp. 1905-1913
    • Merrill, J.T.1    Wallace, D.J.2    Petri, M.3
  • 94
    • 84868144947 scopus 로고    scopus 로고
    • Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study
    • McBride JM, Jiang J, Abbas AR, et al. Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: results of a phase I, placebo-controlled, double-blind, dose-escalation study. Arthritis Rheum 2012;64(11):3666-76
    • (2012) Arthritis Rheum , vol.64 , Issue.11 , pp. 3666-3676
    • McBride, J.M.1    Jiang, J.2    Abbas, A.R.3
  • 95
    • 84873870755 scopus 로고    scopus 로고
    • Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon alpha-kinoid
    • Lauwerys BR, Hachulla E, Spertini F, et al. Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon alpha-kinoid. Arthritis Rheum 2013;65(2): 447-56
    • (2013) Arthritis Rheum , vol.65 , Issue.2 , pp. 447-456
    • Lauwerys, B.R.1    Hachulla, E.2    Spertini, F.3
  • 96
    • 84885464688 scopus 로고    scopus 로고
    • A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice
    • Zhu FG, Jiang W, Bhagat L, et al. A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice. Autoimmunity 2013;46(7):419-28
    • (2013) Autoimmunity , vol.46 , Issue.7 , pp. 419-428
    • Zhu, F.G.1    Jiang, W.2    Bhagat, L.3
  • 97
    • 73449120372 scopus 로고    scopus 로고
    • Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: A systematic review
    • Ruiz-Irastorza G, Ramos-Casals M, Brito-Zeron P, Khamashta MA. Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review. Ann Rheum Dis 2010;69(1):20-8
    • (2010) Ann Rheum Dis , vol.69 , Issue.1 , pp. 20-28
    • Ruiz-Irastorza, G.1    Ramos-Casals, M.2    Brito-Zeron, P.3    Khamashta, M.A.4
  • 98
    • 84882281876 scopus 로고    scopus 로고
    • Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids
    • Lauber K, Keppeler H, Munoz LE, et al. Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids. Cell Death Differ 2013; 20(9):1230-40
    • (2013) Cell Death Differ , vol.20 , Issue.9 , pp. 1230-1240
    • Lauber, K.1    Keppeler, H.2    Munoz, L.E.3


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