메뉴 건너뛰기




Volumn 30, Issue 1, 2014, Pages 99-111

Illuminating breast cancer invasion: Diverse roles for cell-cell interactions

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BREAST TUMOR; CELL COMMUNICATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; HUMAN; METABOLISM; METASTASIS; PATHOLOGY; TUMOR INVASION;

EID: 84906051957     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2014.07.003     Document Type: Review
Times cited : (84)

References (154)
  • 2
    • 77955928161 scopus 로고    scopus 로고
    • Tumors as organs: complex tissues that interface with the entire organism
    • Egeblad M., Nakasone E.S., Werb Z. Tumors as organs: complex tissues that interface with the entire organism. Develop Cell 2010, 18:884-901.
    • (2010) Develop Cell , vol.18 , pp. 884-901
    • Egeblad, M.1    Nakasone, E.S.2    Werb, Z.3
  • 3
    • 33644844519 scopus 로고    scopus 로고
    • Host genetics influence tumour metastasis
    • Hunter K. Host genetics influence tumour metastasis. Nat Rev Cancer 2006, 6:141-146.
    • (2006) Nat Rev Cancer , vol.6 , pp. 141-146
    • Hunter, K.1
  • 4
    • 34247269026 scopus 로고    scopus 로고
    • Genetic determinants of cancer metastasis
    • Nguyen D.X., Massague J. Genetic determinants of cancer metastasis. Nat Rev Genetics 2007, 8:341-352.
    • (2007) Nat Rev Genetics , vol.8 , pp. 341-352
    • Nguyen, D.X.1    Massague, J.2
  • 6
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: a dynamic niche in cancer progression
    • Lu P., Weaver V.M., Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 2012, 196:395-406.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 7
    • 48349094384 scopus 로고    scopus 로고
    • Unraveling the microenvironmental influences on the normal mammary gland and breast cancer
    • Weigelt B., Bissell M.J. Unraveling the microenvironmental influences on the normal mammary gland and breast cancer. Semin Cancer Biol 2008, 18:311-321.
    • (2008) Semin Cancer Biol , vol.18 , pp. 311-321
    • Weigelt, B.1    Bissell, M.J.2
  • 8
    • 0037052448 scopus 로고    scopus 로고
    • Stromal effects on mammary gland development and breast cancer
    • Wiseman B.S., Werb Z. Stromal effects on mammary gland development and breast cancer. Science (New York, NY) 2002, 296:1046-1049.
    • (2002) Science (New York, NY) , vol.296 , pp. 1046-1049
    • Wiseman, B.S.1    Werb, Z.2
  • 9
    • 77957244401 scopus 로고    scopus 로고
    • Cellular mechanisms regulating epithelial morphogenesis and cancer invasion
    • Gray R.S., Cheung K.J., Ewald A.J. Cellular mechanisms regulating epithelial morphogenesis and cancer invasion. Curr Opin Cell Biol 2010, 22:640-650.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 640-650
    • Gray, R.S.1    Cheung, K.J.2    Ewald, A.J.3
  • 10
    • 0016708393 scopus 로고
    • An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions
    • Wellings S.R., Jensen H.M., Marcum R.G. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst 1975, 55:231-273.
    • (1975) J Natl Cancer Inst , vol.55 , pp. 231-273
    • Wellings, S.R.1    Jensen, H.M.2    Marcum, R.G.3
  • 11
    • 3242750437 scopus 로고    scopus 로고
    • Current practical applications of diagnostic immunohistochemistry in breast pathology
    • Lerwill M.F. Current practical applications of diagnostic immunohistochemistry in breast pathology. Am J Surg Pathol 2004, 28:1076-1091.
    • (2004) Am J Surg Pathol , vol.28 , pp. 1076-1091
    • Lerwill, M.F.1
  • 12
    • 33747095513 scopus 로고    scopus 로고
    • Do myoepithelial cells hold the key for breast tumor progression?
    • Polyak K., Hu M. Do myoepithelial cells hold the key for breast tumor progression?. J Mamm Gland Biol Neoplasia 2005, 10:231-247.
    • (2005) J Mamm Gland Biol Neoplasia , vol.10 , pp. 231-247
    • Polyak, K.1    Hu, M.2
  • 14
    • 77957221459 scopus 로고    scopus 로고
    • Dynamic interplay between the collagen scaffold and tumor evolution
    • Egeblad M., Rasch M.G., Weaver V.M. Dynamic interplay between the collagen scaffold and tumor evolution. Curr Opin Cell Biol 2010, 22:697-706.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 697-706
    • Egeblad, M.1    Rasch, M.G.2    Weaver, V.M.3
  • 15
    • 0022891340 scopus 로고
    • Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak H.F. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986, 315:1650-1659.
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 16
    • 43649085395 scopus 로고    scopus 로고
    • Microenvironmental regulation of cancer development
    • Hu M., Polyak K. Microenvironmental regulation of cancer development. Curr Opin Genetics Dev 2008, 18:27-34.
    • (2008) Curr Opin Genetics Dev , vol.18 , pp. 27-34
    • Hu, M.1    Polyak, K.2
  • 18
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121:335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6
  • 19
    • 62549099627 scopus 로고    scopus 로고
    • Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast
    • Hu M., Peluffo G., Chen H., Gelman R., Schnitt S., Polyak K. Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Proc Natl Acad Sci U S A 2009, 106:3372-3377.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3372-3377
    • Hu, M.1    Peluffo, G.2    Chen, H.3    Gelman, R.4    Schnitt, S.5    Polyak, K.6
  • 20
    • 77953966511 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and cancer
    • Pyne N.J., Pyne S. Sphingosine 1-phosphate and cancer. Nat Rev Cancer 2010, 10:489-503.
    • (2010) Nat Rev Cancer , vol.10 , pp. 489-503
    • Pyne, N.J.1    Pyne, S.2
  • 21
    • 84871563123 scopus 로고    scopus 로고
    • Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
    • Luga V., Zhang L., Viloria-Petit A.M., Ogunjimi A.A., Inanlou M.R., Chiu E., et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell. 2012, 151:1542-1556.
    • (2012) Cell. , vol.151 , pp. 1542-1556
    • Luga, V.1    Zhang, L.2    Viloria-Petit, A.M.3    Ogunjimi, A.A.4    Inanlou, M.R.5    Chiu, E.6
  • 22
    • 22144431886 scopus 로고    scopus 로고
    • Autocrine, paracrine and juxtacrine signaling by EGFR ligands
    • Singh A.B., Harris R.C. Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Cell Signal 2005, 17:1183-1193.
    • (2005) Cell Signal , vol.17 , pp. 1183-1193
    • Singh, A.B.1    Harris, R.C.2
  • 24
    • 0024504360 scopus 로고
    • The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction
    • Wong S.T., Winchell L.F., McCune B.K., Earp H.S., Teixido J., Massague J., et al. The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction. Cell 1989, 56:495-506.
    • (1989) Cell , vol.56 , pp. 495-506
    • Wong, S.T.1    Winchell, L.F.2    McCune, B.K.3    Earp, H.S.4    Teixido, J.5    Massague, J.6
  • 25
    • 0025372020 scopus 로고
    • Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation
    • Anklesaria P., Teixido J., Laiho M., Pierce J.H., Greenberger J.S., Massague J. Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation. Proc Natl Acad Sci U S A 1990, 87:3289-3293.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 3289-3293
    • Anklesaria, P.1    Teixido, J.2    Laiho, M.3    Pierce, J.H.4    Greenberger, J.S.5    Massague, J.6
  • 26
    • 0034614938 scopus 로고    scopus 로고
    • The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation
    • Shi W., Fan H., Shum L., Derynck R. The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation. J Cell Biol 2000, 148:591-602.
    • (2000) J Cell Biol , vol.148 , pp. 591-602
    • Shi, W.1    Fan, H.2    Shum, L.3    Derynck, R.4
  • 27
    • 0037077212 scopus 로고    scopus 로고
    • Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix
    • Dallas S.L., Rosser J.L., Mundy G.R., Bonewald L.F. Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix. J Biol Chem 2002, 277:21352-21360.
    • (2002) J Biol Chem , vol.277 , pp. 21352-21360
    • Dallas, S.L.1    Rosser, J.L.2    Mundy, G.R.3    Bonewald, L.F.4
  • 28
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: regulators of the tumor microenvironment
    • Kessenbrock K., Plaks V., Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010, 141:52-67.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 29
    • 47349086991 scopus 로고    scopus 로고
    • MT1-MMP releases latent TGF-beta1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1
    • Tatti O., Vehvilainen P., Lehti K., Keski-Oja J. MT1-MMP releases latent TGF-beta1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1. Exp Cell Res 2008, 314:2501-2514.
    • (2008) Exp Cell Res , vol.314 , pp. 2501-2514
    • Tatti, O.1    Vehvilainen, P.2    Lehti, K.3    Keski-Oja, J.4
  • 30
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A., Homey B., Soto H., Ge N., Catron D., Buchanan M.E., et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001, 410:50-56.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3    Ge, N.4    Catron, D.5    Buchanan, M.E.6
  • 32
    • 4944229701 scopus 로고    scopus 로고
    • A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
    • Wyckoff J., Wang W., Lin E.Y., Wang Y., Pixley F., Stanley E.R., et al. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res 2004, 64:7022-7029.
    • (2004) Cancer Res , vol.64 , pp. 7022-7029
    • Wyckoff, J.1    Wang, W.2    Lin, E.Y.3    Wang, Y.4    Pixley, F.5    Stanley, E.R.6
  • 33
    • 70449526719 scopus 로고    scopus 로고
    • Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
    • Giampieri S., Manning C., Hooper S., Jones L., Hill C.S., Sahai E. Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol 2009, 11:1287-1296.
    • (2009) Nat Cell Biol , vol.11 , pp. 1287-1296
    • Giampieri, S.1    Manning, C.2    Hooper, S.3    Jones, L.4    Hill, C.S.5    Sahai, E.6
  • 34
    • 84884693022 scopus 로고    scopus 로고
    • System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity
    • Rajaram M., Li J., Egeblad M., Powers R.S. System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. PLoS Genetics 2013, 9:e1003789.
    • (2013) PLoS Genetics , vol.9
    • Rajaram, M.1    Li, J.2    Egeblad, M.3    Powers, R.S.4
  • 36
    • 84873804360 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis
    • Chaturvedi P., Gilkes D.M., Wong C.C., Luo W., Zhang H., Wei H., et al. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Investig 2013, 123:189-205.
    • (2013) J Clin Investig , vol.123 , pp. 189-205
    • Chaturvedi, P.1    Gilkes, D.M.2    Wong, C.C.3    Luo, W.4    Zhang, H.5    Wei, H.6
  • 37
    • 73649122504 scopus 로고    scopus 로고
    • Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor
    • Patsialou A., Wyckoff J., Wang Y., Goswami S., Stanley E.R., Condeelis J.S. Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor. Cancer Res 2009, 69:9498-9506.
    • (2009) Cancer Res , vol.69 , pp. 9498-9506
    • Patsialou, A.1    Wyckoff, J.2    Wang, Y.3    Goswami, S.4    Stanley, E.R.5    Condeelis, J.S.6
  • 38
    • 84857834773 scopus 로고    scopus 로고
    • Cadherin-23 mediates heterotypic cell-cell adhesion between breast cancer epithelial cells and fibroblasts
    • Apostolopoulou M., Ligon L. Cadherin-23 mediates heterotypic cell-cell adhesion between breast cancer epithelial cells and fibroblasts. PloS One 2012, 7:e33289.
    • (2012) PloS One , vol.7
    • Apostolopoulou, M.1    Ligon, L.2
  • 40
    • 51049112515 scopus 로고    scopus 로고
    • Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone
    • Tamura D., Hiraga T., Myoui A., Yoshikawa H., Yoneda T. Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone. Int J Oncol 2008, 33:17-24.
    • (2008) Int J Oncol , vol.33 , pp. 17-24
    • Tamura, D.1    Hiraga, T.2    Myoui, A.3    Yoshikawa, H.4    Yoneda, T.5
  • 42
    • 70449185514 scopus 로고
    • Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years
    • Bloom H.J., Richardson W.W. Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer 1957, 11:359-377.
    • (1957) Br J Cancer , vol.11 , pp. 359-377
    • Bloom, H.J.1    Richardson, W.W.2
  • 43
    • 0023415075 scopus 로고
    • The importance of histologic grade in long-term prognosis of breast cancer: a study of 1,010 patients, uniformly treated at the Institut Gustave-Roussy
    • Contesso G., Mouriesse H., Friedman S., Genin J., Sarrazin D., Rouesse J. The importance of histologic grade in long-term prognosis of breast cancer: a study of 1,010 patients, uniformly treated at the Institut Gustave-Roussy. J Clin Oncol 1987, 5:1378-1386.
    • (1987) J Clin Oncol , vol.5 , pp. 1378-1386
    • Contesso, G.1    Mouriesse, H.2    Friedman, S.3    Genin, J.4    Sarrazin, D.5    Rouesse, J.6
  • 44
    • 76549152675 scopus 로고
    • An electron microscope study of human breast cells in fibroadenosis and carcinoma
    • Barton A.A. An electron microscope study of human breast cells in fibroadenosis and carcinoma. Br J Cancer 1964, 18:682-685.
    • (1964) Br J Cancer , vol.18 , pp. 682-685
    • Barton, A.A.1
  • 45
    • 0016277365 scopus 로고
    • Human breast tumor cell lines: identity evaluation by ultrastructure
    • Buehring G.C., Hackett A.J. Human breast tumor cell lines: identity evaluation by ultrastructure. J Natl Cancer Inst 1974, 53:621-629.
    • (1974) J Natl Cancer Inst , vol.53 , pp. 621-629
    • Buehring, G.C.1    Hackett, A.J.2
  • 46
    • 0018236173 scopus 로고
    • Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization
    • Cailleau R., Olive M., Cruciger Q.V. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 1978, 14:911-915.
    • (1978) In Vitro , vol.14 , pp. 911-915
    • Cailleau, R.1    Olive, M.2    Cruciger, Q.V.3
  • 47
    • 0018079661 scopus 로고
    • Establishment and characterization of three new continuous cell lines derived from human breast carcinomas
    • Engel L.W., Young N.A., Tralka T.S., Lippman M.E., O'Brien S.J., Joyce M.J. Establishment and characterization of three new continuous cell lines derived from human breast carcinomas. Cancer Res 1978, 38:3352-3364.
    • (1978) Cancer Res , vol.38 , pp. 3352-3364
    • Engel, L.W.1    Young, N.A.2    Tralka, T.S.3    Lippman, M.E.4    O'Brien, S.J.5    Joyce, M.J.6
  • 48
    • 0019520246 scopus 로고
    • Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist
    • Gabbiani G., Kapanci Y., Barazzone P., Franke W.W. Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol 1981, 104:206-216.
    • (1981) Am J Pathol , vol.104 , pp. 206-216
    • Gabbiani, G.1    Kapanci, Y.2    Barazzone, P.3    Franke, W.W.4
  • 50
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: diversity and escape mechanisms
    • Friedl P., Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 2003, 3:362-374.
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 51
    • 84555179609 scopus 로고    scopus 로고
    • Extracellular matrix degradation and remodeling in development and disease
    • Lu P., Takai K., Weaver V.M., Werb Z. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harbor Persp Biol 2011, 3.
    • (2011) Cold Spring Harbor Persp Biol , pp. 3
    • Lu, P.1    Takai, K.2    Weaver, V.M.3    Werb, Z.4
  • 52
    • 84881519396 scopus 로고    scopus 로고
    • Extracellular matrix determinants and the regulation of cancer cell invasion stratagems
    • Willis A.L., Sabeh F., Li X.Y., Weiss S.J. Extracellular matrix determinants and the regulation of cancer cell invasion stratagems. J Microsc 2013, 251:250-260.
    • (2013) J Microsc , vol.251 , pp. 250-260
    • Willis, A.L.1    Sabeh, F.2    Li, X.Y.3    Weiss, S.J.4
  • 53
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver V.M., Petersen O.W., Wang F., Larabell C.A., Briand P., Damsky C., et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997, 137:231-245.
    • (1997) J Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6
  • 54
    • 84878615544 scopus 로고    scopus 로고
    • The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis
    • Zhang K., Corsa C.A., Ponik S.M., Prior J.L., Piwnica-Worms D., Eliceiri K.W., et al. The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis. Nat Cell Biol 2013, 15:677-687.
    • (2013) Nat Cell Biol , vol.15 , pp. 677-687
    • Zhang, K.1    Corsa, C.A.2    Ponik, S.M.3    Prior, J.L.4    Piwnica-Worms, D.5    Eliceiri, K.W.6
  • 55
    • 84880028245 scopus 로고    scopus 로고
    • Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force
    • Wolf K., Te Lindert M., Krause M., Alexander S., Te Riet J., Willis A.L., et al. Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol 2013, 201:1069-1084.
    • (2013) J Cell Biol , vol.201 , pp. 1069-1084
    • Wolf, K.1    Te Lindert, M.2    Krause, M.3    Alexander, S.4    Te Riet, J.5    Willis, A.L.6
  • 56
    • 84903385203 scopus 로고    scopus 로고
    • Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement
    • Haeger A., Krause M., Wolf K., Friedl P. Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement. Biochim Biophys Acta 2014, 1840:2386-2395.
    • (2014) Biochim Biophys Acta , vol.1840 , pp. 2386-2395
    • Haeger, A.1    Krause, M.2    Wolf, K.3    Friedl, P.4
  • 57
    • 84880331739 scopus 로고    scopus 로고
    • Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions
    • Tozluoglu M., Tournier A.L., Jenkins R.P., Hooper S., Bates P.A., Sahai E. Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions. Nat Cell Biol 2013, 15:751-762.
    • (2013) Nat Cell Biol , vol.15 , pp. 751-762
    • Tozluoglu, M.1    Tournier, A.L.2    Jenkins, R.P.3    Hooper, S.4    Bates, P.A.5    Sahai, E.6
  • 59
    • 70450222098 scopus 로고    scopus 로고
    • Matrix crosslinking forces tumor progression by enhancing integrin signaling
    • Levental K.R., Yu H., Kass L., Lakins J.N., Egeblad M., Erler J.T., et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 2009, 139:891-906.
    • (2009) Cell , vol.139 , pp. 891-906
    • Levental, K.R.1    Yu, H.2    Kass, L.3    Lakins, J.N.4    Egeblad, M.5    Erler, J.T.6
  • 60
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
    • Guy C.T., Cardiff R.D., Muller W.J. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 1992, 12:954-961.
    • (1992) Mol Cell Biol , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 61
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • Herschkowitz J.I., Simin K., Weigman V.J., Mikaelian I., Usary J., Hu Z., et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007, 8:R76.
    • (2007) Genome Biol , vol.8
    • Herschkowitz, J.I.1    Simin, K.2    Weigman, V.J.3    Mikaelian, I.4    Usary, J.5    Hu, Z.6
  • 62
    • 84887398348 scopus 로고    scopus 로고
    • Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
    • Pfefferle A.D., Herschkowitz J.I., Usary J., Harrell J.C., Spike B.T., Adams J.R., et al. Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol. 2013, 14:R125.
    • (2013) Genome Biol. , vol.14
    • Pfefferle, A.D.1    Herschkowitz, J.I.2    Usary, J.3    Harrell, J.C.4    Spike, B.T.5    Adams, J.R.6
  • 63
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin E.Y., Nguyen A.V., Russell R.G., Pollard J.W. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 2001, 193:727-740.
    • (2001) J Exp Med , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 64
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • Condeelis J., Segall J.E. Intravital imaging of cell movement in tumours. Nat Rev Cancer 2003, 3:921-930.
    • (2003) Nat Rev Cancer , vol.3 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2
  • 66
    • 64249152007 scopus 로고    scopus 로고
    • Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy
    • discussion 65
    • Egeblad M., Ewald A.J., Askautrud H.A., Truitt M.L., Welm B.E., Bainbridge E., et al. Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Disease Models Mech 2008, 1:155-167. discussion 65.
    • (2008) Disease Models Mech , vol.1 , pp. 155-167
    • Egeblad, M.1    Ewald, A.J.2    Askautrud, H.A.3    Truitt, M.L.4    Welm, B.E.5    Bainbridge, E.6
  • 67
    • 34648832906 scopus 로고    scopus 로고
    • Illuminating the metastatic process
    • Sahai E. Illuminating the metastatic process. Nat Rev Cancer 2007, 7:737-749.
    • (2007) Nat Rev Cancer , vol.7 , pp. 737-749
    • Sahai, E.1
  • 68
    • 84894581126 scopus 로고    scopus 로고
    • Collective invasion in breast cancer requires a conserved basal epithelial program
    • Cheung K.J., Gabrielson E., Werb Z., Ewald A.J. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell 2013, 155:1639-1651.
    • (2013) Cell , vol.155 , pp. 1639-1651
    • Cheung, K.J.1    Gabrielson, E.2    Werb, Z.3    Ewald, A.J.4
  • 69
    • 84866885625 scopus 로고    scopus 로고
    • ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium
    • Nguyen-Ngoc K.V., Cheung K.J., Brenot A., Shamir E.R., Gray R.S., Hines W.C., et al. ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A 2012, 109:E2595-E2604.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Nguyen-Ngoc, K.V.1    Cheung, K.J.2    Brenot, A.3    Shamir, E.R.4    Gray, R.S.5    Hines, W.C.6
  • 70
    • 84881557402 scopus 로고    scopus 로고
    • Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro
    • Dovas A., Patsialou A., Harney A.S., Condeelis J., Cox D. Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro. J Microsc 2013, 251:261-269.
    • (2013) J Microsc , vol.251 , pp. 261-269
    • Dovas, A.1    Patsialou, A.2    Harney, A.S.3    Condeelis, J.4    Cox, D.5
  • 71
    • 84873383258 scopus 로고    scopus 로고
    • Isolation of mouse mammary organoids for long-term time-lapse imaging
    • Ewald A.J. Isolation of mouse mammary organoids for long-term time-lapse imaging. Cold Spring Harbor Protoc 2013, 2013:130-133.
    • (2013) Cold Spring Harbor Protoc , vol.2013 , pp. 130-133
    • Ewald, A.J.1
  • 72
    • 84877810500 scopus 로고    scopus 로고
    • Caught in the act: revealing the metastatic process by live imaging
    • Fein M.R., Egeblad M. Caught in the act: revealing the metastatic process by live imaging. Disease Models Mech 2013, 6:580-593.
    • (2013) Disease Models Mech , vol.6 , pp. 580-593
    • Fein, M.R.1    Egeblad, M.2
  • 74
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009, 9:265-273.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 75
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 76
    • 84885915873 scopus 로고    scopus 로고
    • Epithelial-mesenchymal plasticity in carcinoma metastasis
    • Tsai J.H., Yang J. Epithelial-mesenchymal plasticity in carcinoma metastasis. Genes Dev 2013, 27:2192-2206.
    • (2013) Genes Dev , vol.27 , pp. 2192-2206
    • Tsai, J.H.1    Yang, J.2
  • 77
    • 0642336851 scopus 로고    scopus 로고
    • E-cadherin expression in primary carcinomas of the breast and its distant metastases
    • Kowalski P.J., Rubin M.A., Kleer C.G. E-cadherin expression in primary carcinomas of the breast and its distant metastases. Breast Cancer Res: BCR 2003, 5:R217-R222.
    • (2003) Breast Cancer Res: BCR , vol.5
    • Kowalski, P.J.1    Rubin, M.A.2    Kleer, C.G.3
  • 78
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery J.P. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002, 2:442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 79
    • 66249109653 scopus 로고    scopus 로고
    • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
    • Hennessy B.T., Gonzalez-Angulo A.M., Stemke-Hale K., Gilcrease M.Z., Krishnamurthy S., Lee J.S., et al. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res 2009, 69:4116-4124.
    • (2009) Cancer Res , vol.69 , pp. 4116-4124
    • Hennessy, B.T.1    Gonzalez-Angulo, A.M.2    Stemke-Hale, K.3    Gilcrease, M.Z.4    Krishnamurthy, S.5    Lee, J.S.6
  • 81
    • 77957262381 scopus 로고    scopus 로고
    • Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
    • Taube J.H., Herschkowitz J.I., Komurov K., Zhou A.Y., Gupta S., Yang J., et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A 2010, 107:15449-15454.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15449-15454
    • Taube, J.H.1    Herschkowitz, J.I.2    Komurov, K.3    Zhou, A.Y.4    Gupta, S.5    Yang, J.6
  • 82
    • 84890429780 scopus 로고    scopus 로고
    • Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes
    • Prat A., Karginova O., Parker J.S., Fan C., He X., Bixby L., et al. Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes. Breast Cancer Res Treat 2013, 142:237-255.
    • (2013) Breast Cancer Res Treat , vol.142 , pp. 237-255
    • Prat, A.1    Karginova, O.2    Parker, J.S.3    Fan, C.4    He, X.5    Bixby, L.6
  • 83
    • 78951482208 scopus 로고    scopus 로고
    • Deconstructing the molecular portraits of breast cancer
    • Prat A., Perou C.M. Deconstructing the molecular portraits of breast cancer. Mol Oncol 2011, 5:5-23.
    • (2011) Mol Oncol , vol.5 , pp. 5-23
    • Prat, A.1    Perou, C.M.2
  • 84
    • 38849093994 scopus 로고    scopus 로고
    • Direct evidence for epithelial-mesenchymal transitions in breast cancer
    • Trimboli A.J., Fukino K., de Bruin A., Wei G., Shen L., Tanner S.M., et al. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res 2008, 68:937-945.
    • (2008) Cancer Res , vol.68 , pp. 937-945
    • Trimboli, A.J.1    Fukino, K.2    de Bruin, A.3    Wei, G.4    Shen, L.5    Tanner, S.M.6
  • 85
    • 33645758275 scopus 로고    scopus 로고
    • Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton
    • Wicki A., Lehembre F., Wick N., Hantusch B., Kerjaschki D., Christofori G. Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 2006, 9:261-272.
    • (2006) Cancer Cell , vol.9 , pp. 261-272
    • Wicki, A.1    Lehembre, F.2    Wick, N.3    Hantusch, B.4    Kerjaschki, D.5    Christofori, G.6
  • 86
    • 84869000970 scopus 로고    scopus 로고
    • Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis
    • McCaffrey L.M., Montalbano J., Mihai C., Macara I.G. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell 2012, 22:601-614.
    • (2012) Cancer Cell , vol.22 , pp. 601-614
    • McCaffrey, L.M.1    Montalbano, J.2    Mihai, C.3    Macara, I.G.4
  • 87
    • 84873410310 scopus 로고    scopus 로고
    • Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion
    • Xue B., Krishnamurthy K., Allred D.C., Muthuswamy S.K. Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. Nat Cell Biol 2013, 15:189-200.
    • (2013) Nat Cell Biol , vol.15 , pp. 189-200
    • Xue, B.1    Krishnamurthy, K.2    Allred, D.C.3    Muthuswamy, S.K.4
  • 88
    • 84895772208 scopus 로고    scopus 로고
    • Twist1-induced dissemination preserves epithelial identity and requires E-cadherin
    • Shamir E.R., Pappalardo E., Jorgens D.M., Coutinho K., Tsai W.T., Aziz K., et al. Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol 2014, 204:839-856.
    • (2014) J Cell Biol , vol.204 , pp. 839-856
    • Shamir, E.R.1    Pappalardo, E.2    Jorgens, D.M.3    Coutinho, K.4    Tsai, W.T.5    Aziz, K.6
  • 89
    • 0028912755 scopus 로고
    • Adhesion systems in normal breast and in invasive breast carcinoma
    • Glukhova M., Koteliansky V., Sastre X., Thiery J.P. Adhesion systems in normal breast and in invasive breast carcinoma. Am J Pathol 1995, 146:706-716.
    • (1995) Am J Pathol , vol.146 , pp. 706-716
    • Glukhova, M.1    Koteliansky, V.2    Sastre, X.3    Thiery, J.P.4
  • 90
    • 0027770015 scopus 로고
    • Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas
    • Moll R., Mitze M., Frixen U.H., Birchmeier W. Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol 1993, 143:1731-1742.
    • (1993) Am J Pathol , vol.143 , pp. 1731-1742
    • Moll, R.1    Mitze, M.2    Frixen, U.H.3    Birchmeier, W.4
  • 91
    • 0027530351 scopus 로고
    • Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis
    • Oka H., Shiozaki H., Kobayashi K., Inoue M., Tahara H., Kobayashi T., et al. Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 1993, 53:1696-1701.
    • (1993) Cancer Res , vol.53 , pp. 1696-1701
    • Oka, H.1    Shiozaki, H.2    Kobayashi, K.3    Inoue, M.4    Tahara, H.5    Kobayashi, T.6
  • 92
    • 20644472457 scopus 로고    scopus 로고
    • E-cadherin expression in invasive non-lobular carcinoma of the breast and its prognostic significance
    • Rakha E.A., Abd El Rehim D., Pinder S.E., Lewis S.A., Ellis I.O. E-cadherin expression in invasive non-lobular carcinoma of the breast and its prognostic significance. Histopathology 2005, 46:685-693.
    • (2005) Histopathology , vol.46 , pp. 685-693
    • Rakha, E.A.1    Abd El Rehim, D.2    Pinder, S.E.3    Lewis, S.A.4    Ellis, I.O.5
  • 93
    • 33750367989 scopus 로고    scopus 로고
    • E-cadherin immunohistochemical expression as a prognostic factor in infiltrating ductal carcinoma of the breast: a systematic review and meta-analysis
    • Gould Rothberg B.E., Bracken M.B. E-cadherin immunohistochemical expression as a prognostic factor in infiltrating ductal carcinoma of the breast: a systematic review and meta-analysis. Breast Cancer Res Treat 2006, 100:139-148.
    • (2006) Breast Cancer Res Treat , vol.100 , pp. 139-148
    • Gould Rothberg, B.E.1    Bracken, M.B.2
  • 94
    • 27644467501 scopus 로고    scopus 로고
    • Clinical characteristics of different histologic types of breast cancer
    • Li C.I., Uribe D.J., Daling J.R. Clinical characteristics of different histologic types of breast cancer. Br J Cancer 2005, 93:1046-1052.
    • (2005) Br J Cancer , vol.93 , pp. 1046-1052
    • Li, C.I.1    Uribe, D.J.2    Daling, J.R.3
  • 95
    • 80053406107 scopus 로고    scopus 로고
    • Breast cancer-one term, many entities?
    • Bertos N.R., Park M. Breast cancer-one term, many entities?. J Clin Investig 2011, 121:3789-3796.
    • (2011) J Clin Investig , vol.121 , pp. 3789-3796
    • Bertos, N.R.1    Park, M.2
  • 96
    • 0034852853 scopus 로고    scopus 로고
    • The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression
    • Berx G., Van Roy F. The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. Breast Cancer Res: BCR 2001, 3:289-293.
    • (2001) Breast Cancer Res: BCR , vol.3 , pp. 289-293
    • Berx, G.1    Van Roy, F.2
  • 97
    • 33750614651 scopus 로고    scopus 로고
    • Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis
    • Derksen P.W., Liu X., Saridin F., van der Gulden H., Zevenhoven J., Evers B., et al. Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. Cancer Cell 2006, 10:437-449.
    • (2006) Cancer Cell , vol.10 , pp. 437-449
    • Derksen, P.W.1    Liu, X.2    Saridin, F.3    van der Gulden, H.4    Zevenhoven, J.5    Evers, B.6
  • 98
    • 0033957255 scopus 로고    scopus 로고
    • Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [see comments]
    • Bukholm I.K., Nesland J.M., Borresen-Dale A.L. Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [see comments]. J Pathol 2000, 190:15-19.
    • (2000) J Pathol , vol.190 , pp. 15-19
    • Bukholm, I.K.1    Nesland, J.M.2    Borresen-Dale, A.L.3
  • 99
    • 0032749503 scopus 로고    scopus 로고
    • A novel human xenograft model of inflammatory breast cancer
    • Alpaugh M.L., Tomlinson J.S., Shao Z.M., Barsky S.H. A novel human xenograft model of inflammatory breast cancer. Cancer Res 1999, 59:5079-5084.
    • (1999) Cancer Res , vol.59 , pp. 5079-5084
    • Alpaugh, M.L.1    Tomlinson, J.S.2    Shao, Z.M.3    Barsky, S.H.4
  • 100
    • 0037430060 scopus 로고    scopus 로고
    • Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression
    • Colpaert C.G., Vermeulen P.B., Benoy I., Soubry A., van Roy F., van Beest P., et al. Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression. Br J Cancer 2003, 88:718-725.
    • (2003) Br J Cancer , vol.88 , pp. 718-725
    • Colpaert, C.G.1    Vermeulen, P.B.2    Benoy, I.3    Soubry, A.4    van Roy, F.5    van Beest, P.6
  • 101
    • 0035031712 scopus 로고    scopus 로고
    • Persistent E-cadherin expression in inflammatory breast cancer
    • Kleer C.G., van Golen K.L., Braun T., Merajver S.D. Persistent E-cadherin expression in inflammatory breast cancer. Modern Pathol 2001, 14:458-464.
    • (2001) Modern Pathol , vol.14 , pp. 458-464
    • Kleer, C.G.1    van Golen, K.L.2    Braun, T.3    Merajver, S.D.4
  • 103
    • 67649528138 scopus 로고    scopus 로고
    • Collective cell migration in morphogenesis, regeneration and cancer
    • Friedl P., Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 2009, 10:445-457.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 445-457
    • Friedl, P.1    Gilmour, D.2
  • 104
    • 0028866016 scopus 로고
    • Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro
    • Friedl P., Noble P.B., Walton P.A., Laird D.W., Chauvin P.J., Tabah R.J., et al. Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro. Cancer Res 1995, 55:4557-4560.
    • (1995) Cancer Res , vol.55 , pp. 4557-4560
    • Friedl, P.1    Noble, P.B.2    Walton, P.A.3    Laird, D.W.4    Chauvin, P.J.5    Tabah, R.J.6
  • 105
    • 0036532136 scopus 로고    scopus 로고
    • Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies
    • Hegerfeldt Y., Tusch M., Brocker E.B., Friedl P. Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies. Cancer Res 2002, 62:2125-2130.
    • (2002) Cancer Res , vol.62 , pp. 2125-2130
    • Hegerfeldt, Y.1    Tusch, M.2    Brocker, E.B.3    Friedl, P.4
  • 106
    • 36749013537 scopus 로고    scopus 로고
    • Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
    • Gaggioli C., Hooper S., Hidalgo-Carcedo C., Grosse R., Marshall J.F., Harrington K., et al. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007, 9:1392-1400.
    • (2007) Nat Cell Biol , vol.9 , pp. 1392-1400
    • Gaggioli, C.1    Hooper, S.2    Hidalgo-Carcedo, C.3    Grosse, R.4    Marshall, J.F.5    Harrington, K.6
  • 107
    • 80155169013 scopus 로고    scopus 로고
    • Breast cancer subtype-specific interactions with the microenvironment dictate mechanisms of invasion
    • Dang T.T., Prechtl A.M., Pearson G.W. Breast cancer subtype-specific interactions with the microenvironment dictate mechanisms of invasion. Cancer Res 2011, 71:6857-6866.
    • (2011) Cancer Res , vol.71 , pp. 6857-6866
    • Dang, T.T.1    Prechtl, A.M.2    Pearson, G.W.3
  • 108
    • 84878615570 scopus 로고    scopus 로고
    • Mechanotransduction and YAP-dependent matrix remodeling is required for the generation and maintenance of cancer-associated fibroblasts
    • Calvo F., Ege N., Grande-Garcia A., Hooper S., Jenkins R.P., Chaudhry S.I., et al. Mechanotransduction and YAP-dependent matrix remodeling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol 2013, 15:637-646.
    • (2013) Nat Cell Biol , vol.15 , pp. 637-646
    • Calvo, F.1    Ege, N.2    Grande-Garcia, A.3    Hooper, S.4    Jenkins, R.P.5    Chaudhry, S.I.6
  • 109
    • 84863104141 scopus 로고    scopus 로고
    • Lack of transforming growth factor-beta signaling promotes collective cancer cell invasion through tumor-stromal crosstalk
    • Matise L.A., Palmer T.D., Ashby W.J., Nashabi A., Chytil A., Aakre M., et al. Lack of transforming growth factor-beta signaling promotes collective cancer cell invasion through tumor-stromal crosstalk. Breast Cancer Res: BCR 2012, 14:R98.
    • (2012) Breast Cancer Res: BCR , vol.14
    • Matise, L.A.1    Palmer, T.D.2    Ashby, W.J.3    Nashabi, A.4    Chytil, A.5    Aakre, M.6
  • 110
    • 75549083303 scopus 로고    scopus 로고
    • Tumor heterogeneity: causes and consequences
    • Marusyk A., Polyak K. Tumor heterogeneity: causes and consequences. Biochim Biophys Acta 2010, 1805:105-117.
    • (2010) Biochim Biophys Acta , vol.1805 , pp. 105-117
    • Marusyk, A.1    Polyak, K.2
  • 111
    • 84878554127 scopus 로고    scopus 로고
    • Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model
    • Carey S.P., Starchenko A., McGregor A.L., Reinhart-King C.A. Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model. Clin Exp Metastasis 2013, 30:615-630.
    • (2013) Clin Exp Metastasis , vol.30 , pp. 615-630
    • Carey, S.P.1    Starchenko, A.2    McGregor, A.L.3    Reinhart-King, C.A.4
  • 112
    • 34547569807 scopus 로고    scopus 로고
    • Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
    • Wolf K., Wu Y.I., Liu Y., Geiger J., Tam E., Overall C., et al. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol 2007, 9:893-904.
    • (2007) Nat Cell Biol , vol.9 , pp. 893-904
    • Wolf, K.1    Wu, Y.I.2    Liu, Y.3    Geiger, J.4    Tam, E.5    Overall, C.6
  • 113
    • 84895479294 scopus 로고    scopus 로고
    • Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells
    • Reffay M., Parrini M.C., Cochet-Escartin O., Ladoux B., Buguin A., Coscoy S., et al. Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells. Nat Cell Biol 2014, 16:217-223.
    • (2014) Nat Cell Biol , vol.16 , pp. 217-223
    • Reffay, M.1    Parrini, M.C.2    Cochet-Escartin, O.3    Ladoux, B.4    Buguin, A.5    Coscoy, S.6
  • 114
    • 84868711769 scopus 로고    scopus 로고
    • Fellow travellers: emergent properties of collective cell migration
    • Rorth P. Fellow travellers: emergent properties of collective cell migration. EMBO Rep 2012, 13:984-991.
    • (2012) EMBO Rep , vol.13 , pp. 984-991
    • Rorth, P.1
  • 115
    • 84878990582 scopus 로고    scopus 로고
    • Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis
    • Cheung W.K., Zhao M., Liu Z., Stevens L.E., Cao P.D., Fang J.E., et al. Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell 2013, 23:725-738.
    • (2013) Cancer Cell , vol.23 , pp. 725-738
    • Cheung, W.K.1    Zhao, M.2    Liu, Z.3    Stevens, L.E.4    Cao, P.D.5    Fang, J.E.6
  • 116
    • 84895435815 scopus 로고    scopus 로고
    • Keratin 19: a key role player in the invasion of human hepatocellular carcinomas
    • Govaere O., Komuta M., Berkers J., Spee B., Janssen C., de Luca F., et al. Keratin 19: a key role player in the invasion of human hepatocellular carcinomas. Gut 2014, 63:674-685.
    • (2014) Gut , vol.63 , pp. 674-685
    • Govaere, O.1    Komuta, M.2    Berkers, J.3    Spee, B.4    Janssen, C.5    de Luca, F.6
  • 117
    • 84883477750 scopus 로고    scopus 로고
    • Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-beta-deficient mouse mammary carcinomas
    • Pickup M.W., Laklai H., Acerbi I., Owens P., Gorska A.E., Chytil A., et al. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-beta-deficient mouse mammary carcinomas. Cancer Res 2013, 73:5336-5346.
    • (2013) Cancer Res , vol.73 , pp. 5336-5346
    • Pickup, M.W.1    Laklai, H.2    Acerbi, I.3    Owens, P.4    Gorska, A.E.5    Chytil, A.6
  • 118
    • 84897543202 scopus 로고    scopus 로고
    • A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies
    • Wang C.C., Bajikar S.S., Jamal L., Atkins K.A., Janes K.A. A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies. Nat Cell Biol 2014, 16:345-356.
    • (2014) Nat Cell Biol , vol.16 , pp. 345-356
    • Wang, C.C.1    Bajikar, S.S.2    Jamal, L.3    Atkins, K.A.4    Janes, K.A.5
  • 119
    • 31044433663 scopus 로고    scopus 로고
    • Macrophages: obligate partners for tumor cell migration, invasion, and metastasis
    • Condeelis J., Pollard J.W. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006, 124:263-266.
    • (2006) Cell , vol.124 , pp. 263-266
    • Condeelis, J.1    Pollard, J.W.2
  • 120
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
    • Leek R.D., Landers R.J., Harris A.L., Lewis C.E. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer 1999, 79:991-995.
    • (1999) Br J Cancer , vol.79 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 121
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • Qian B.Z., Pollard J.W. Macrophage diversity enhances tumor progression and metastasis. Cell 2010, 141:39-51.
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 122
    • 24744454660 scopus 로고    scopus 로고
    • Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density
    • Tsutsui S., Yasuda K., Suzuki K., Tahara K., Higashi H., Era S. Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density. Oncol Rep 2005, 14:425-431.
    • (2005) Oncol Rep , vol.14 , pp. 425-431
    • Tsutsui, S.1    Yasuda, K.2    Suzuki, K.3    Tahara, K.4    Higashi, H.5    Era, S.6
  • 123
    • 34047246527 scopus 로고    scopus 로고
    • Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors
    • Wyckoff J.B., Wang Y., Lin E.Y., Li J.F., Goswami S., Stanley E.R., et al. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res 2007, 67:2649-2656.
    • (2007) Cancer Res , vol.67 , pp. 2649-2656
    • Wyckoff, J.B.1    Wang, Y.2    Lin, E.Y.3    Li, J.F.4    Goswami, S.5    Stanley, E.R.6
  • 124
  • 125
    • 3342904989 scopus 로고    scopus 로고
    • Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases
    • Hagemann T., Robinson S.C., Schulz M., Trumper L., Balkwill F.R., Binder C. Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases. Carcinogenesis 2004, 25:1543-1549.
    • (2004) Carcinogenesis , vol.25 , pp. 1543-1549
    • Hagemann, T.1    Robinson, S.C.2    Schulz, M.3    Trumper, L.4    Balkwill, F.R.5    Binder, C.6
  • 126
    • 65249126907 scopus 로고    scopus 로고
    • Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination
    • Robinson B.D., Sica G.L., Liu Y.F., Rohan T.E., Gertler F.B., Condeelis J.S., et al. Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination. Clin Cancer Res 2009, 15:2433-2441.
    • (2009) Clin Cancer Res , vol.15 , pp. 2433-2441
    • Robinson, B.D.1    Sica, G.L.2    Liu, Y.F.3    Rohan, T.E.4    Gertler, F.B.5    Condeelis, J.S.6
  • 127
    • 67651160649 scopus 로고    scopus 로고
    • CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo D.G., Barreto J.B., Andreu P., Vasquez L., Tawfik D., Kolhatkar N., et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009, 16:91-102.
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • DeNardo, D.G.1    Barreto, J.B.2    Andreu, P.3    Vasquez, L.4    Tawfik, D.5    Kolhatkar, N.6
  • 128
    • 69249222379 scopus 로고    scopus 로고
    • Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN
    • Fridlender Z.G., Sun J., Kim S., Kapoor V., Cheng G., Ling L., et al. Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell 2009, 16:183-194.
    • (2009) Cancer Cell , vol.16 , pp. 183-194
    • Fridlender, Z.G.1    Sun, J.2    Kim, S.3    Kapoor, V.4    Cheng, G.5    Ling, L.6
  • 129
    • 76149146398 scopus 로고    scopus 로고
    • IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
    • Gocheva V., Wang H.W., Gadea B.B., Shree T., Hunter K.E., Garfall A.L., et al. IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev 2010, 24:241-255.
    • (2010) Genes Dev , vol.24 , pp. 241-255
    • Gocheva, V.1    Wang, H.W.2    Gadea, B.B.3    Shree, T.4    Hunter, K.E.5    Garfall, A.L.6
  • 130
    • 33747602354 scopus 로고    scopus 로고
    • Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis
    • Nozawa H., Chiu C., Hanahan D. Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis. Proc Natl Acad Sci U S A 2006, 103:12493-12498.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12493-12498
    • Nozawa, H.1    Chiu, C.2    Hanahan, D.3
  • 131
    • 33846407655 scopus 로고    scopus 로고
    • Mammographic density and the risk and detection of breast cancer
    • Boyd N.F., Guo H., Martin L.J., Sun L., Stone J., Fishell E., et al. Mammographic density and the risk and detection of breast cancer. N Engl J Med 2007, 356:227-236.
    • (2007) N Engl J Med , vol.356 , pp. 227-236
    • Boyd, N.F.1    Guo, H.2    Martin, L.J.3    Sun, L.4    Stone, J.5    Fishell, E.6
  • 132
    • 33745683831 scopus 로고    scopus 로고
    • Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis
    • McCormack V.A., dos Santos Silva I. Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis. Cancer Epidemiol Biomarkers Prevention 2006, 15:1159-1169.
    • (2006) Cancer Epidemiol Biomarkers Prevention , vol.15 , pp. 1159-1169
    • McCormack, V.A.1    dos Santos Silva, I.2
  • 133
    • 0017082939 scopus 로고
    • Risk for breast cancer development determined by mammographic parenchymal pattern
    • Wolfe J.N. Risk for breast cancer development determined by mammographic parenchymal pattern. Cancer 1976, 37:2486-2492.
    • (1976) Cancer , vol.37 , pp. 2486-2492
    • Wolfe, J.N.1
  • 134
    • 0022032394 scopus 로고
    • Quantitative determination of collagen types present in the ductal infiltrating carcinoma of human mammary gland
    • Pucci Minafra I., Luparello C., Sciarrino S., Tomasino R.M., Minafra S. Quantitative determination of collagen types present in the ductal infiltrating carcinoma of human mammary gland. Cell Biol Int Rep 1985, 9:291-296.
    • (1985) Cell Biol Int Rep , vol.9 , pp. 291-296
    • Pucci Minafra, I.1    Luparello, C.2    Sciarrino, S.3    Tomasino, R.M.4    Minafra, S.5
  • 135
    • 20944437572 scopus 로고    scopus 로고
    • The association of measured breast tissue characteristics with mammographic density and other risk factors for breast cancer
    • Li T., Sun L., Miller N., Nicklee T., Woo J., Hulse-Smith L., et al. The association of measured breast tissue characteristics with mammographic density and other risk factors for breast cancer. Cancer Epidemiol Biomarkers Prevention 2005, 14:343-349.
    • (2005) Cancer Epidemiol Biomarkers Prevention , vol.14 , pp. 343-349
    • Li, T.1    Sun, L.2    Miller, N.3    Nicklee, T.4    Woo, J.5    Hulse-Smith, L.6
  • 136
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S., Ross K.N., Lander E.S., Golub T.R. A molecular signature of metastasis in primary solid tumors. Nat Genetics 2003, 33:49-54.
    • (2003) Nat Genetics , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 139
    • 80052499480 scopus 로고    scopus 로고
    • Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2
    • Lyons T.R., O'Brien J., Borges V.F., Conklin M.W., Keely P.J., Eliceiri K.W., et al. Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nat Med 2011, 17:1109-1115.
    • (2011) Nat Med , vol.17 , pp. 1109-1115
    • Lyons, T.R.1    O'Brien, J.2    Borges, V.F.3    Conklin, M.W.4    Keely, P.J.5    Eliceiri, K.W.6
  • 140
    • 84885451271 scopus 로고    scopus 로고
    • Collagen architecture in pregnancy-induced protection from breast cancer
    • Maller O., Hansen K.C., Lyons T.R., Acerbi I., Weaver V.M., Prekeris R., et al. Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci 2013, 126:4108-4110.
    • (2013) J Cell Sci , vol.126 , pp. 4108-4110
    • Maller, O.1    Hansen, K.C.2    Lyons, T.R.3    Acerbi, I.4    Weaver, V.M.5    Prekeris, R.6
  • 142
    • 84878615570 scopus 로고    scopus 로고
    • Mechanotransduction and YAP-dependent matrix remodeling is required for the generation and maintenance of cancer-associated fibroblasts
    • Calvo F., Ege N., Grande-Garcia A., Hooper S., Jenkins R.P., Chaudhry S.I., et al. Mechanotransduction and YAP-dependent matrix remodeling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol 2013, 15:637-646.
    • (2013) Nat Cell Biol , vol.15 , pp. 637-646
    • Calvo, F.1    Ege, N.2    Grande-Garcia, A.3    Hooper, S.4    Jenkins, R.P.5    Chaudhry, S.I.6
  • 144
    • 0035835829 scopus 로고    scopus 로고
    • Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
    • Elenbaas B., Weinberg R.A. Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp Cell Res 2001, 264:169-184.
    • (2001) Exp Cell Res , vol.264 , pp. 169-184
    • Elenbaas, B.1    Weinberg, R.A.2
  • 145
    • 0031788894 scopus 로고    scopus 로고
    • Aberrant type I and type III collagen gene expression in human breast cancer in vivo
    • Kauppila S., Stenback F., Risteli J., Jukkola A., Risteli L. Aberrant type I and type III collagen gene expression in human breast cancer in vivo. J Pathol 1998, 186:262-268.
    • (1998) J Pathol , vol.186 , pp. 262-268
    • Kauppila, S.1    Stenback, F.2    Risteli, J.3    Jukkola, A.4    Risteli, L.5
  • 146
    • 69249156451 scopus 로고    scopus 로고
    • Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion
    • Sabeh F., Li X.Y., Saunders T.L., Rowe R.G., Weiss S.J. Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion. J Biol Chem 2009, 284:23001-23011.
    • (2009) J Biol Chem , vol.284 , pp. 23001-23011
    • Sabeh, F.1    Li, X.Y.2    Saunders, T.L.3    Rowe, R.G.4    Weiss, S.J.5
  • 147
    • 79551693066 scopus 로고    scopus 로고
    • Circulating tumor cells: approaches to isolation and characterization
    • Yu M., Stott S., Toner M., Maheswaran S., Haber D.A. Circulating tumor cells: approaches to isolation and characterization. J Cell Biol 2011, 192:373-382.
    • (2011) J Cell Biol , vol.192 , pp. 373-382
    • Yu, M.1    Stott, S.2    Toner, M.3    Maheswaran, S.4    Haber, D.A.5
  • 149
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 151
    • 0034696279 scopus 로고    scopus 로고
    • The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting
    • Cardiff R.D., Anver M.R., Gusterson B.A., Hennighausen L., Jensen R.A., Merino M.J., et al. The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene 2000, 19:968-988.
    • (2000) Oncogene , vol.19 , pp. 968-988
    • Cardiff, R.D.1    Anver, M.R.2    Gusterson, B.A.3    Hennighausen, L.4    Jensen, R.A.5    Merino, M.J.6
  • 153
    • 34548268026 scopus 로고    scopus 로고
    • Modelling breast cancer: one size does not fit all
    • Vargo-Gogola T., Rosen J.M. Modelling breast cancer: one size does not fit all. Nat Rev Cancer 2007, 7:659-672.
    • (2007) Nat Rev Cancer , vol.7 , pp. 659-672
    • Vargo-Gogola, T.1    Rosen, J.M.2
  • 154
    • 12344252751 scopus 로고    scopus 로고
    • Mechanisms of cancer cell invasion
    • Sahai E. Mechanisms of cancer cell invasion. Curr Opin Genetics Dev 2005, 15:87-96.
    • (2005) Curr Opin Genetics Dev , vol.15 , pp. 87-96
    • Sahai, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.