Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

Nature Cell Biology

Volumn 15, Issue 7, 2013, Pages 751-762

  Tozluoǧlu, Melda ^a   Tournier, Alexander L ^a   Jenkins, Robert P ^a   Hooper, Steven ^a   Bates, Paul A ^a   Sahai, Erik ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; DASATINIB; MYOSIN ADENOSINE TRIPHOSPHATASE;

ACTIN POLYMERIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL ADHESION; CELL MEMBRANE; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DRUG MEGADOSE; EXTRACELLULAR MATRIX; FEMALE; GEOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MATHEMATICAL MODEL; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL;

ACTINS; CELL ADHESION; CELL MEMBRANE; CELL MOVEMENT; CELL-MATRIX JUNCTIONS; COMPUTER SIMULATION; EXTRACELLULAR MATRIX; HUMANS; INTEGRINS; MODELS, THEORETICAL; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES;

EID: 84880331739     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2775     Document Type: Article

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