Inflammatory breast cancer (IBC): Clues for targeted therapies

Breast Cancer Research and Treatment

Volumn 140, Issue 1, 2013, Pages 23-33

  Fernandez, Sandra V ^a,b,f   Robertson, Fredika M ^d   Pei, Jianming ^a   Aburto Chumpitaz, Lucy ^a   Mu, Zhaomei ^a,b   Chu, Khoi ^d   Alpaugh, R K ^a   Huang, Yong ^e   Cao, Yu ^a   Ye, Zaiming ^d   Cai, Kathy Q ^a   Boley, Kimberly M ^d   Klein Szanto, Andres J ^a   Devarajan, Karthik ^a   Addya, Sankar ^c   Cristofanilli, Massimo ^a,b,f  

^a FOX CHASE CANCER CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

ALK; ATAD2; CD44; FAK1 PTK2; MYC; NOTCH3

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANAPLASTIC LYMPHOMA KINASE; BETA CATENIN; CD151 ANTIGEN; CELL MARKER; EPITHELIAL CELL ADHESION MOLECULE; FOCAL ADHESION KINASE 1; HERMES ANTIGEN; MYC PROTEIN; NOTCH3 RECEPTOR; PROTEIN ATAD2; UNCLASSIFIED DRUG; UVOMORULIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOIKIS; ARTICLE; BRAIN METASTASIS; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL SUSPENSION; CHROMOSOME 8Q; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATORY BREAST CANCER; LUNG METASTASIS; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLEURA EFFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SCID MOUSE; TRIPLE NEGATIVE BREAST CANCER; TUMOR EMBOLISM; TUMOR XENOGRAFT;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTIGENS, CD4; BRAIN NEOPLASMS; CADHERINS; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 8; DNA-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FOCAL ADHESION KINASE 1; FOCAL ADHESION KINASE 2; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; HUMANS; INFLAMMATORY BREAST NEOPLASMS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MICE; MICE, SCID; MOLECULAR TARGETED THERAPY; NEOPLASMS, EXPERIMENTAL; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, NOTCH; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84880271935     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2600-4     Document Type: Article

References (40)

1. Hance KW, Anderson WF, Devesa SS, Young HA, Levine PH (2005) Trends in inflammatory breast carcinoma incidence and survival: the surveillance, epidemiology, and end results program at the National Cancer Institute. J Natl Cancer Inst 97:966-975 (Pubitemid 41430562)
2. Chia S, Swain SM, Byrd DR, Mankoff DA (2008) Locally advanced and inflammatory breast cancer. J Clin Oncol 26:786-790 (Pubitemid 351264392)
3. Dawood S, et al. (2011) Differences in survival among women with stage III inflammatory and noninflammatory locally advanced breast cancer appear early: a large population-based study. Cancer 117:1819-1826
4. Robertson FM, et al. (2010) Inflammatory breast cancer: the disease, the biology, the treatment. CA Cancer J Clin 60:351-375
5. Cristofanilli M, et al. (2007) Inflammatory breast cancer (IBC) and patterns of recurrence: understanding the biology of a unique disease. Cancer 110:1436-1444 (Pubitemid 47463056)
6. Molckovsky A, Fitzgerald B, Freedman O, Heisey R, Clemons M (2009) Approach to inflammatory breast cancer. Can Fam Physician 55:25-31
7. Alpaugh ML, Tomlinson JS, Kasraeian S, Barsky SH (2002) Cooperative role of E-cadherin and sialyl-Lewis X/A-deficient MUC1 in the passive dissemination of tumor emboli in inflammatory breast carcinoma. Oncogene 21:3631-3643 (Pubitemid 34587695)
8. Bertucci F, Finetti P, Birnbaum D, Viens P (2010) Gene expression profiling of inflammatory breast cancer. Cancer 116:2783-2793
9. Van Laere SJ, et al. (2006) Identification of cell-of-origin breast tumor subtypes in inflammatory breast cancer by gene expression profiling. Breast Cancer Res Treat 95:243-255
10. Willmarth NE, Ethier SP (2006) Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells. J Biol Chem 281:37728-37737 (Pubitemid 46042076)
11. Neve RM, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10:515-527 (Pubitemid 44854747)
12. Forozan F, et al. (1999) Molecular cytogenetic analysis of 11 new breast cancer cell lines. Br J Cancer 81:1328-1334
13. Charafe-Jauffret E, et al. (2006) Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 25:2273-2284
14. Kurebayashi J, et al. (1999) Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6. Br J Cancer 79:707-717 (Pubitemid 29082094)
15. Alpaugh ML, Tomlinson JS, Shao ZM, Barsky SH (1999) A novel human xenograft model of inflammatory breast cancer. Cancer Res 59:5079-5084 (Pubitemid 29503962)
16. Shirakawa K, et al. (2001) Absence of endothelial cells, central necrosis, and fibrosis are associated with aggressive inflammatory breast cancer. Cancer Res 61:445-451 (Pubitemid 32128594)
17. Xiao Y, Ye Y, Yearsley K, Jones S, Barsky SH (2008) The lymphovascular embolus of inflammatory breast cancer expresses a stem cell-like phenotype. Am J Pathol 173:561-574
18. Tomlinson JS, Alpaugh ML, Barsky SH (2001) An intact overexpressed E-cadherin/alpha, beta-catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma. Cancer Res 61:5231-5241 (Pubitemid 32681558)
19. Dontu G, et al. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17:1253-1270 (Pubitemid 36583168)
20. Robertson F, et al. (2012) Genomic profiling of pre-clinical models of inflammatory breast cancer identifies a signature of epithelial plasticity and suppression of TGF B signalling. J Clin Exp Pathol 2:1-11
21. Li C, Hung Wong W (2001) Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biol 2: RESEARCH 0032
22. Gautier L, Cope L, Bolstad BM, Irizarry RA (2004) affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20:307-315 (Pubitemid 38262761)
23. Irizarry RA, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4:249-264
24. Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98:5116-5121 (Pubitemid 32397092)
25. Lo AC, et al. (2009) Analysis of RhoC expression and lymphovascular emboli in inflammatory vs non-inflammatory breast cancers in Egyptian patients. Breast 18:55-59
26. Friedl P, Gilmour D (2009) Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 10:445-457
27. Chui MH (2012) Insights into cancer metastasis from a clinicopathologic perspective: Epithelial mesenchymal transition is not a necessary step. Int J Cancer 132(7):1487-1495
28. Mani SA, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704-715 (Pubitemid 351636299)
29. Friedl P, Wolf K (2003) Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3:362-374 (Pubitemid 37328856)
30. Xiao Y, et al. (2011) The lymphovascular embolus of inflammatory breast cancer exhibits a Notch 3 addiction. Oncogene 30:287-300
31. Bekhouche I, et al. (2011) High-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes. PLoS ONE 6:e16950
32. Eilers M, Eisenman RN (2008) Myc's broad reach. Genes Dev 22:2755-2766
33. Ciro M, et al. (2009) ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors. Cancer Res 69:8491-8498
34. Filippakopoulos P, et al. (2010) Selective inhibition of BET bromodomains. Nature 468:1067-1073
35. Muller S, Filippakopoulos P, Knapp S (2011) Bromodomains as therapeutic targets. Expert Rev Mol Med 13:e29
36. Delmore JE, et al. (2011) BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146:904-917
37. Frisch SM, Screaton RA (2001) Anoikis mechanisms. Curr Opin Cell Biol 13:555-562 (Pubitemid 32817013)
38. Hu G, et al. (2009) MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell 15:9-20
39. Gabarra-Niecko V, Schaller MD, Dunty JM (2003) FAK regulates biological processes important for the pathogenesis of cancer. Cancer Metastasis Rev 22:359-374 (Pubitemid 36791892)
40. Cance WG, et al. (2000) Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res 6:2417-2423 (Pubitemid 30399210)