메뉴 건너뛰기




Volumn 52, Issue 9, 2014, Pages 1085-1093

Hydroxysafflor yellow A suppresses liver fibrosis induced by carbon tetrachloride with high-fat diet by regulating PPAR-γ/p38 MAPK signaling

Author keywords

Hepatic fibrosis; Herb; HFD; HSYA; Peroxisome proliferator activated receptor

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; GELATINASE A; HYDROXYPROLINE; HYDROXYSAFFLOR YELLOW A; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL PRODUCT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHALCONE; QUINONE DERIVATIVE;

EID: 84906050806     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.877491     Document Type: Article
Times cited : (39)

References (43)
  • 1
    • 0034624004 scopus 로고    scopus 로고
    • Growth regulation via p38 mitogen-activated protein kinase in developing liver
    • Awad MM, Enslen H, Boylan JM, et al. (2000). Growth regulation via p38 mitogen-activated protein kinase in developing liver. J Biol Chem 275:38716-21.
    • (2000) J Biol Chem , vol.275 , pp. 38716-38721
    • Awad, M.M.1    Enslen, H.2    Boylan, J.M.3
  • 2
    • 0142151769 scopus 로고    scopus 로고
    • Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
    • Canbay A, Feldstein AE, Higuchi H, et al. (2003). Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology 38:1188-98.
    • (2003) Hepatology , vol.38 , pp. 1188-1198
    • Canbay, A.1    Feldstein, A.E.2    Higuchi, H.3
  • 3
    • 67349155604 scopus 로고    scopus 로고
    • Therapeutic efficacy of traditional Chinese medicine 319 recipe on hepatic fibrosis induced by carbon tetrachloride in rats
    • Cheung KF, Ye DW, Yang ZF, et al. (2009). Therapeutic efficacy of traditional Chinese medicine 319 recipe on hepatic fibrosis induced by carbon tetrachloride in rats. J Ethnopharmacol 124:142-50.
    • (2009) J Ethnopharmacol , vol.124 , pp. 142-150
    • Cheung, K.F.1    Ye, D.W.2    Yang, Z.F.3
  • 5
    • 78650522908 scopus 로고    scopus 로고
    • Hepatoprotective activity of berberine is mediated by inhibition of TNF-alpha, COX-2, and iNOS expression in CCl(4)-intoxicated mice
    • Domitrovi R, Jakovac H, Blagojevi G. (2011). Hepatoprotective activity of berberine is mediated by inhibition of TNF-alpha, COX-2, and iNOS expression in CCl(4)-intoxicated mice. Toxicology 280:33-43.
    • (2011) Toxicology , vol.280 , pp. 33-43
    • Domitrovi, R.1    Jakovac, H.2    Blagojevi, G.3
  • 6
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis-from bench to bedside
    • Friedman SL. (2003). Liver fibrosis-from bench to bedside. J Hepatol 38:S38-53.
    • (2003) J Hepatol , vol.38
    • Friedman, S.L.1
  • 7
    • 77949808406 scopus 로고    scopus 로고
    • Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disorders
    • Goldstein DM, Kuglstatter A, Lou Y, Soth MJ. (2010). Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disorders. J Med Chem 53:2345-53.
    • (2010) J Med Chem , vol.53 , pp. 2345-2353
    • Goldstein, D.M.1    Kuglstatter, A.2    Lou, Y.3    Soth, M.J.4
  • 8
    • 0031829438 scopus 로고    scopus 로고
    • Serum markers as tools to monitor liver fibrosis
    • Hayasaka A, Saisho H. (1998). Serum markers as tools to monitor liver fibrosis. Digestion 59:381-4.
    • (1998) Digestion , vol.59 , pp. 381-384
    • Hayasaka, A.1    Saisho, H.2
  • 9
    • 38349169370 scopus 로고    scopus 로고
    • Protective effects of hydroxysafflor yellow A on acute and chronic congestive cardiac failure mediated by reducing ET-1, NOS and oxidative stress in rats
    • He H, Yang X, Shi M, et al. (2008). Protective effects of hydroxysafflor yellow A on acute and chronic congestive cardiac failure mediated by reducing ET-1, NOS and oxidative stress in rats. J Pharm Pharmacol 60:115-23.
    • (2008) J Pharm Pharmacol , vol.60 , pp. 115-123
    • He, H.1    Yang, X.2    Shi, M.3
  • 10
    • 39249083049 scopus 로고    scopus 로고
    • Matrix metalloproteinase gene delivery for liver fibrosis
    • Iimuro Y, Brenner DA. (2008). Matrix metalloproteinase gene delivery for liver fibrosis. Pharm Res 25:249-58.
    • (2008) Pharm Res , vol.25 , pp. 249-258
    • Iimuro, Y.1    Brenner, D.A.2
  • 11
    • 33846951514 scopus 로고    scopus 로고
    • Emerging insights into transforming growth factor beta Smad signal in hepatic fibrogenesis
    • Inagaki Y, Okazaki I. (2007). Emerging insights into transforming growth factor beta Smad signal in hepatic fibrogenesis. Gut 56: 284-92.
    • (2007) Gut , vol.56 , pp. 284-292
    • Inagaki, Y.1    Okazaki, I.2
  • 12
    • 84868091753 scopus 로고    scopus 로고
    • Group IVA phospholipase A2 participates in the progression of hepatic fibrosis
    • Ishihara K, Miyazaki A, Nabe T, et al. (2012). Group IVA phospholipase A2 participates in the progression of hepatic fibrosis. FASEB J 26: 4111-21.
    • (2012) FASEB J , vol.26 , pp. 4111-4121
    • Ishihara, K.1    Miyazaki, A.2    Nabe, T.3
  • 13
    • 77956634470 scopus 로고    scopus 로고
    • High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis
    • Kohli R, Kirby M, Xanthakos SA, et al. (2010). High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology 52:934-44.
    • (2010) Hepatology , vol.52 , pp. 934-944
    • Kohli, R.1    Kirby, M.2    Xanthakos, S.A.3
  • 14
    • 84879514564 scopus 로고    scopus 로고
    • A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice
    • Kohli R, Kirby M, Xanthakos SA, et al. (2013). A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. Clin Exp Pharmacol Physiol 40:422-30.
    • (2013) Clin Exp Pharmacol Physiol , vol.40 , pp. 422-430
    • Kohli, R.1    Kirby, M.2    Xanthakos, S.A.3
  • 15
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • Lee CH, Olson P, Evans RM. (2003). Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 144:2201-7.
    • (2003) Endocrinology , vol.144 , pp. 2201-2207
    • Lee, C.H.1    Olson, P.2    Evans, R.M.3
  • 16
    • 84860920725 scopus 로고    scopus 로고
    • Protective effects of kaerophyllin against liver fibrogenesis in rats
    • Lee TF, Lin YL, Huang YT. (2012). Protective effects of kaerophyllin against liver fibrogenesis in rats. Eur J Clin Invest 42:607-16.
    • (2012) Eur J Clin Invest , vol.42 , pp. 607-616
    • Lee, T.F.1    Lin, Y.L.2    Huang, Y.T.3
  • 17
    • 0036095120 scopus 로고    scopus 로고
    • The role of hepatic stellate cells and transforming growth factor-beta(1) in cystic fibrosis liver disease
    • Lewindon PJ, Pereira TN, Hoskins AC, et al. (2002). The role of hepatic stellate cells and transforming growth factor-beta(1) in cystic fibrosis liver disease. Am J Pathol 160:1705-15.
    • (2002) Am J Pathol , vol.160 , pp. 1705-1715
    • Lewindon, P.J.1    Pereira, T.N.2    Hoskins, A.C.3
  • 18
    • 84861183376 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A induces apoptosis in activated hepatic stellate cells through ERK1/2 pathway in vitro
    • Li CC, Yang CZ, Li XM, et al. (2012). Hydroxysafflor yellow A induces apoptosis in activated hepatic stellate cells through ERK1/2 pathway in vitro. Eur J Pharm Sci 46:397-404.
    • (2012) Eur J Pharm Sci , vol.46 , pp. 397-404
    • Li, C.C.1    Yang, C.Z.2    Li, X.M.3
  • 19
    • 84875407645 scopus 로고    scopus 로고
    • Astragaloside IV suppresses collagen production of activated hepatic stellate cells via oxidative stress-mediated p38 MAPK pathway
    • Li X, Wang X, Han C, et al. (2013). Astragaloside IV suppresses collagen production of activated hepatic stellate cells via oxidative stress-mediated p38 MAPK pathway. Free Radic Biol Med 60:168-76.
    • (2013) Free Radic Biol Med , vol.60 , pp. 168-176
    • Li, X.1    Wang, X.2    Han, C.3
  • 20
    • 84862900594 scopus 로고    scopus 로고
    • Protective effect of Fufang-Liu- Yue-Qing, a traditional Chinese herbal formula, on CCl4 induced liver fibrosis in rats
    • Lin X, Zhang S, Huang Q, et al. (2012). Protective effect of Fufang-Liu- Yue-Qing, a traditional Chinese herbal formula, on CCl4 induced liver fibrosis in rats. J Ethnopharmacol 142:548-56.
    • (2012) J Ethnopharmacol , vol.142 , pp. 548-556
    • Lin, X.1    Zhang, S.2    Huang, Q.3
  • 21
    • 0034680787 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptors and hepatic stellate cell activation
    • Miyahara T, Schrum L, Rippe R, et al. (2000). Peroxisome proliferatoractivated receptors and hepatic stellate cell activation. J Biol Chem 275:35715-22.
    • (2000) J Biol Chem , vol.275 , pp. 35715-35722
    • Miyahara, T.1    Schrum, L.2    Rippe, R.3
  • 22
    • 0030011961 scopus 로고    scopus 로고
    • Clinical significance of serum hyaluronan in patients with chronic viral liver disease
    • Murawaki Y, Ikuta Y, Koda M, et al. (1996). Clinical significance of serum hyaluronan in patients with chronic viral liver disease. J Gastroenterol Hepatol 11:459-65.
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 459-465
    • Murawaki, Y.1    Ikuta, Y.2    Koda, M.3
  • 23
    • 84875340329 scopus 로고    scopus 로고
    • The antihepatic fibrotic effects of fluorofenidone via MAPK signalling pathways
    • Peng Y, Yang H, Zhu T, et al. (2013). The antihepatic fibrotic effects of fluorofenidone via MAPK signalling pathways. Eur J Clin Invest 43: 358-68.
    • (2013) Eur J Clin Invest , vol.43 , pp. 358-368
    • Peng, Y.1    Yang, H.2    Zhu, T.3
  • 24
    • 77956924615 scopus 로고    scopus 로고
    • Liver fibrosis: A dynamic and potentially reversible process
    • Povero D, Busletta C, Novo E, et al. (2010). Liver fibrosis: A dynamic and potentially reversible process. Histol Histopathol 25:1075-91.
    • (2010) Histol Histopathol , vol.25 , pp. 1075-1091
    • Povero, D.1    Busletta, C.2    Novo, E.3
  • 25
    • 1342302807 scopus 로고    scopus 로고
    • Herbal medicine Sho-saiko-to(TJ-9) increases expression matrix metalloproteinases (MMPs) with reduced expression of tissue inhibitor of metalloproteinases (TIMPs) in rat stellate cell medicine Sho-saiko-to(TJ-9) increases expression matrix metalloproteinases (MMPs) with reduced expression of tissue inhibitor of metalloproteinases (TIMPs) in rat stellate cell
    • Sakaida I, Hironaka K, Kimura T, et al. (2004). Herbal medicine Sho-saiko-to(TJ-9) increases expression matrix metalloproteinases (MMPs) with reduced expression of tissue inhibitor of metalloproteinases (TIMPs) in rat stellate cell medicine Sho-saiko-to(TJ-9) increases expression matrix metalloproteinases (MMPs) with reduced expression of tissue inhibitor of metalloproteinases (TIMPs) in rat stellate cell. Life Sci 74:2251-63.
    • (2004) Life Sci , vol.74 , pp. 2251-2263
    • Sakaida, I.1    Hironaka, K.2    Kimura, T.3
  • 26
    • 84880668528 scopus 로고    scopus 로고
    • Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice
    • Seth RK, Kumar A, Das S, et al. (2013). Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice. Toxicol Sci 134:291-303.
    • (2013) Toxicol Sci , vol.134 , pp. 291-303
    • Seth, R.K.1    Kumar, A.2    Das, S.3
  • 27
    • 14244257340 scopus 로고    scopus 로고
    • Adipogenic transcriptional regulation of hepatic stellate cells
    • She H, Xiong S, Hazra S, Tsukamoto H. (2005). Adipogenic transcriptional regulation of hepatic stellate cells. J Biol Chem 280:4959-67.
    • (2005) J Biol Chem , vol.280 , pp. 4959-4967
    • She, H.1    Xiong, S.2    Hazra, S.3    Tsukamoto, H.4
  • 28
    • 79956055056 scopus 로고    scopus 로고
    • A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice
    • Sinha-Hikim I, Sinha-Hikim AP, Shen R, et al. (2011). A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. Exp Mol Pathol 91:419-28.
    • (2011) Exp Mol Pathol , vol.91 , pp. 419-428
    • Sinha-Hikim, I.1    Sinha-Hikim, A.P.2    Shen, R.3
  • 29
    • 84873354313 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A inhibits lipopolysaccharide-induced inflammatory signal transduction in human alveolar epithelial A549 cells
    • Song L, Zhu Y, Jin M, Zang B. (2013). Hydroxysafflor yellow A inhibits lipopolysaccharide-induced inflammatory signal transduction in human alveolar epithelial A549 cells. Fitoterapia 84:107-14.
    • (2013) Fitoterapia , vol.84 , pp. 107-114
    • Song, L.1    Zhu, Y.2    Jin, M.3    Zang, B.4
  • 30
    • 78649670589 scopus 로고    scopus 로고
    • The ability of hydroxysafflor yellow A to attenuate lipopolysaccharide- induced pulmonary inflammatory injury in mice
    • Sun CY, Pei CQ, Zang BX, et al. (2010). The ability of hydroxysafflor yellow A to attenuate lipopolysaccharide-induced pulmonary inflammatory injury in mice. Phytother Res 24:1788-95.
    • (2010) Phytother Res , vol.24 , pp. 1788-1795
    • Sun, C.Y.1    Pei, C.Q.2    Zang, B.X.3
  • 31
    • 84865461003 scopus 로고    scopus 로고
    • Neuroprotection of hydroxysafflor yellow A in the transient focal ischemia: Inhibition of protein oxidation/nitration, 12/15-lipoxygenase and blood-brain barrier disruption
    • Sun L, Yang L, Xu YW, et al. (2012). Neuroprotection of hydroxysafflor yellow A in the transient focal ischemia: Inhibition of protein oxidation/nitration, 12/15-lipoxygenase and blood-brain barrier disruption. Brain Res 1473:227-35.
    • (2012) Brain Res , vol.1473 , pp. 227-235
    • Sun, L.1    Yang, L.2    Xu, Y.W.3
  • 32
    • 77954954234 scopus 로고    scopus 로고
    • Carthamus tinctorius L. Prevents LPS-induced TNFalpha signaling activation and cell apoptosis through JNK1/2-NFkappaB pathway inhibition in H9c2 cardiomyoblast cells
    • Tien YC, Lin JY, Lai CH, et al. (2010). Carthamus tinctorius L. prevents LPS-induced TNFalpha signaling activation and cell apoptosis through JNK1/2-NFkappaB pathway inhibition in H9c2 cardiomyoblast cells. J Ethnopharmacol 130:505-13.
    • (2010) J Ethnopharmacol , vol.130 , pp. 505-513
    • Tien, Y.C.1    Lin, J.Y.2    Lai, C.H.3
  • 33
    • 77956268976 scopus 로고    scopus 로고
    • Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells
    • Trebicka J, Hennenberg M, Odenthal M, et al. (2010). Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells. J Hepatol 53:702-12.
    • (2010) J Hepatol , vol.53 , pp. 702-712
    • Trebicka, J.1    Hennenberg, M.2    Odenthal, M.3
  • 34
    • 84876420052 scopus 로고    scopus 로고
    • Activation of PPAR-g is required for hydroxysafflor yellow A of Carthamus tinctorius to attenuate hepatic fibrosis induced by oxidative stress
    • Wang CY, Liu Q, Huang QX, et al. (2013). Activation of PPAR-g is required for hydroxysafflor yellow A of Carthamus tinctorius to attenuate hepatic fibrosis induced by oxidative stress. Phytomedicine 20:592-9.
    • (2013) Phytomedicine , vol.20 , pp. 592-599
    • Wang, C.Y.1    Liu, Q.2    Huang, Q.X.3
  • 35
    • 73749084035 scopus 로고    scopus 로고
    • Antifibrotic effects of CGX, a traditional herbal formula, and its mechanisms in rats
    • Wang JH, Shin JW, Son JY, et al. (2010). Antifibrotic effects of CGX, a traditional herbal formula, and its mechanisms in rats. J Ethnopharmacol 127:534-42.
    • (2010) J Ethnopharmacol , vol.127 , pp. 534-542
    • Wang, J.H.1    Shin, J.W.2    Son, J.Y.3
  • 36
    • 84895076381 scopus 로고    scopus 로고
    • Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in nonalcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/ Akt/FoxO1, and NF-kappa B pathways
    • [Online], [last accessed 21 Mar 2013]
    • Xiao J, Ho CT, Liong EC, et al. (2013). Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in nonalcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/ Akt/FoxO1, and NF-kappa B pathways. Eur J Nutr [Online]. Available from: http://dx.doi.org/10.1007/s00394- 013-0516-8 [last accessed 21 Mar 2013].
    • (2013) Eur J Nutr
    • Xiao, J.1    Ho, C.T.2    Liong, E.C.3
  • 37
    • 84876460403 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor delta protects against obesity-related glomerulopathy through the P38MAPK pathway
    • Yan Z, Ni Y, Wang P, et al. (2013). Peroxisome proliferatoractivated receptor delta protects against obesity-related glomerulopathy through the P38MAPK pathway. Obesity (Sliver Spring) 21: 538-45.
    • (2013) Obesity (Sliver Spring) , vol.21 , pp. 538-545
    • Yan, Z.1    Ni, Y.2    Wang, P.3
  • 38
    • 33749322086 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis
    • Yang L, Chan CC, Kwon OS, et al. (2006). Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis. Am J Physiol Gastrointest Liver Physiol 291:G902-11.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Yang, L.1    Chan, C.C.2    Kwon, O.S.3
  • 39
    • 45449097043 scopus 로고    scopus 로고
    • Compound Astragalus and Salvia miltiorrhiza extract exerts anti-fibrosis by mediating TGF-beta/Smad signaling in myofibroblasts
    • Yang Y, Yang S, Chen M, et al. (2008). Compound Astragalus and Salvia miltiorrhiza extract exerts anti-fibrosis by mediating TGF-beta/Smad signaling in myofibroblasts. J Ethnopharmacol 118: 264-70.
    • (2008) J Ethnopharmacol , vol.118 , pp. 264-270
    • Yang, Y.1    Yang, S.2    Chen, M.3
  • 40
    • 84861990525 scopus 로고    scopus 로고
    • Polyprenols from Taxus chinensis var. Mairei prevent the development of CCl4-induced liver fibrosis in rats
    • Yu J, Wang Y, Qian H, et al. (2012). Polyprenols from Taxus chinensis var. mairei prevent the development of CCl4-induced liver fibrosis in rats. J Ethnopharmacol 142:151-60.
    • (2012) J Ethnopharmacol , vol.142 , pp. 151-160
    • Yu, J.1    Wang, Y.2    Qian, H.3
  • 41
    • 81155139258 scopus 로고    scopus 로고
    • Traditional Chinese medicine syndrome distribution in chronic hepatitis B populations: A systematic review
    • Zeng XX, Bian ZX, Wu TX, et al. (2011). Traditional Chinese medicine syndrome distribution in chronic hepatitis B populations: A systematic review. Am J Chin Med 39:1061-74.
    • (2011) Am J Chin Med , vol.39 , pp. 1061-1074
    • Zeng, X.X.1    Bian, Z.X.2    Wu, T.X.3
  • 42
    • 79956075733 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A protects against chronic carbon tetrachloride-induced liver fibrosis
    • Zhang Y, Guo J, Dong H, et al. (2011). Hydroxysafflor yellow A protects against chronic carbon tetrachloride-induced liver fibrosis. Eur J Pharmacol 660:438-44.
    • (2011) Eur J Pharmacol , vol.660 , pp. 438-444
    • Zhang, Y.1    Guo, J.2    Dong, H.3
  • 43
    • 77952955100 scopus 로고    scopus 로고
    • Leptin inhibits PPARgamma gene expression in hepatic stellate cells in the mouse model of liver damage
    • Zhou Y, Jia X, Qin J, et al. (2010). Leptin inhibits PPARgamma gene expression in hepatic stellate cells in the mouse model of liver damage. Mol Cell Endocrinol 323:193-200.
    • (2010) Mol Cell Endocrinol , vol.323 , pp. 193-200
    • Zhou, Y.1    Jia, X.2    Qin, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.