A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice

Experimental and Molecular Pathology

Volumn 91, Issue 1, 2011, Pages 419-428

  Sinha Hikim, Indrani ^a,b   Sinha Hikim, Amiya P ^a,b   Shen, Ruoqing ^a   Kim, H ^c   French, Samuel W ^d   Vaziri, Nosratola D ^c   Crum, Albert ^e   Rajavashisth, Tripathi B ^a,b   Norris, Keith C ^a,b  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HARBOR UCLA MEDICAL CENTER   (United States)

^e Proimmune   (United States)

Author keywords

Antioxidant; Apoptosis; Hepatic steatosis; High fat diet; Lipogenesis; Oxidative stress

Indexed keywords

ALBUMIN; ANTIOXIDANT; APOLIPOPROTEIN E; CASPASE 3; CASPASE 9; CYSTEINE; F 1; FT 061452; GLUTATHIONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; RE 39734; SELENOMETHIONINE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG MECHANISM; ELECTRON MICROSCOPY; ENZYME ACTIVATION; FAT CONTENT; FATTY LIVER; HEPATOMEGALY; LIPOGENESIS; LIVER HISTOLOGY; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WEIGHT GAIN;

ACETYLCYSTEINE; ANIMALS; APOLIPOPROTEINS E; BCL-2-ASSOCIATED X PROTEIN; DIETARY FATS; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FATTY LIVER; FREE RADICAL SCAVENGERS; HEPATOCYTES; LIPOGENESIS; MALE; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; OBESITY; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SELENOMETHIONINE;

MUS;

EID: 79956055056     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2011.04.009     Document Type: Article

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