Activation of PPARγ is required for hydroxysafflor yellow A of Carthamus tinctorius to attenuate hepatic fibrosis induced by oxidative stress

Phytomedicine

Volumn 20, Issue 7, 2013, Pages 592-599

  Wang, C Y ^a,b   Liu, Q ^a   Huang, Q X ^c   Liu, J T ^b   He, Y H ^a   Lu, J J ^a   Bai, X Y ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^c YANTAI YUHUANGDING HOSPITAL   (China)

Author keywords

SMA; Carthamus tinctorius; Hepatic fibrosis; Hydroxysafflor yellow A; MMP 2; PPAR ; TGF 1

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; GELATINASE A; HYDROGEN PEROXIDE; HYDROXYSAFFLOR YELLOW A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HISTOPATHOLOGY; IN VITRO STUDY; LIVER FIBROSIS; LIVER INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAFFLOWER; STELLATE CELL; UPREGULATION; WESTERN BLOTTING;

ACTINS; ANILIDES; ANIMALS; ANTIOXIDANTS; CARTHAMUS TINCTORIUS; CELL PROLIFERATION; CHALCONE; ENZYMES; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MALE; OXIDATIVE STRESS; PPAR GAMMA; QUINONES; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

CARTHAMUS TINCTORIUS;

EID: 84876420052     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.02.001     Document Type: Article

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