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Volumn 15, Issue 12, 2014, Pages 1761-1764

Improved stability and half-life of fluorinated phosphotriesterase using Rosetta

(7) Yang, Ching Yao a Renfrew, P Douglas b Olsen, Andrew J a Zhang, Michelle a Yuvienco, Carlo a Bonneau, Richard a,b Montclare, Jin Kim a,b,c

a POLYTECHNIC UNIVERSITY (United States)

b NEW YORK UNIVERSITY (United States)

c SUNY Downstate Medical Center (United States)

Author keywords

amino acids; biosynthesis; computational design; half life; noncanonical amino acids; stability

Indexed keywords

4 FLUOROPHENYLALANINE; AMINO ACID; PHOSPHOTRIESTERASE;

ARTICLE; ENZYME ACTIVITY; ENZYME STABILITY; GENE MUTATION; HALF LIFE TIME; MOLECULAR LIBRARY; NONHUMAN; PRIORITY JOURNAL; ROOM TEMPERATURE; ROSETTA; THERMOSTABILITY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HALOGENATION; METABOLISM; MUTATION; TEMPERATURE;

AMINO ACIDS; ENZYME STABILITY; HALF-LIFE; HALOGENATION; MODELS, MOLECULAR; MUTATION; P-FLUOROPHENYLALANINE; PHOSPHORIC TRIESTER HYDROLASES; TEMPERATURE;

EID: 84906048356 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201402062 Document Type: Article

Times cited : (21)

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