Computational design of a symmetric homodimer using β-strand assembly

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 51, 2011, Pages 20562-20567

  Stranges, P Benjamin ^a   Machius, Mischa ^a   Miley, Michael J ^a   Tripathy, Ashutosh ^a,b   Kuhlman, Brian ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Computational protein design; Protein design; Protein interface design; Rosetta

Indexed keywords

GAMMA ADAPTIN; HOMODIMER; MONOMER;

AMINO ACID SEQUENCE; ARTICLE; BETA SHEET; BETA STRAND; BINDING AFFINITY; COMPUTER AIDED DESIGN; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR WEIGHT; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN STRUCTURE; SIMULATION; WILD TYPE;

CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA; ESCHERICHIA COLI; LIGHT; MOLECULAR CONFORMATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SCATTERING, RADIATION; SOFTWARE; SOLVENTS; SURFACE PROPERTIES; THERMODYNAMICS; ULTRACENTRIFUGATION;

EID: 84855514179     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115124108     Document Type: Article

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