Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS

Journal of Biological Chemistry

Volumn 289, Issue 33, 2014, Pages 22888-22899

  Mueller, Andre Michael ^a   Yoon, Bo Hyung ^a   Sadiq, Saud Ahmed ^a  

^a Uro Center of New York   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CELLS; CYTOLOGY; GENE EXPRESSION; MAMMALS; T-CELLS; TISSUE;

ANTIGEN PRESENTATION; CENTRAL NERVOUS SYSTEMS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HYALURONAN SYNTHESIS; INFLAMMATORY GENE EXPRESSIONS; MULTIPLE SCLEROSIS LESIONS; TOLL-LIKE RECEPTORS 2; VASCULAR ENDOTHELIUM;

HYALURONIC ACID;

HYALURONIC ACID; HYMECROMONE; PROTEOLIPID PROTEIN; STROMAL CELL DERIVED FACTOR 1; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CXCL12 PROTEIN, MOUSE; CXCL12 PROTEIN, RAT; HETEROCYCLIC COMPOUND; PLERIXAFOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC INFILTRATION; MOLECULAR DYNAMICS; MULTIPLE SCLEROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY T LYMPHOCYTE; TH1 CELL; ADOPTIVE TRANSFER; ANIMAL; BIOSYNTHESIS; CENTRAL NERVOUS SYSTEM; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE; PATHOLOGY;

ADOPTIVE TRANSFER; ANIMALS; ANTI-HIV AGENTS; CENTRAL NERVOUS SYSTEM; CHEMOKINE CXCL12; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION REGULATION; HETEROCYCLIC COMPOUNDS; HYALURONIC ACID; INFLAMMATION; MICE; RATS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 84905970448     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.559583     Document Type: Article

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