Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts

Arthritis and Rheumatism

Volumn 65, Issue 5, 2013, Pages 1160-1170

  Yoshioka, Yutaka ^a   Kozawa, Eiji ^a   Urakawa, Hiroshi ^a   Arai, Eisuke ^a   Futamura, Naohisa ^a   Zhuo, Lisheng ^b   Kimata, Koji ^b   Ishiguro, Naoki ^a   Nishida, Yoshihiro ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; HYALURONIC ACID; HYALURONIC ACID BINDING PROTEIN; HYMECROMONE; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BINDING ASSAY; BIOTINYLATION; CARTILAGE CELL; CONTROLLED STUDY; DISEASE SEVERITY; FIBROBLAST; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SCORING SYSTEM; STAINING; SYNOVIOCYTE; SYNOVIUM;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; EDEMA; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; HINDLIMB; HUMANS; HYALURONIC ACID; HYMECROMONE; MICE; MICE, INBRED DBA; RNA, MESSENGER; RNA, SMALL INTERFERING; STIFLE; SYNOVIAL MEMBRANE;

EID: 84876542585     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37861     Document Type: Article

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