Identification and characterization of novel inhibitors of mammalian aspartyl aminopeptidase

Molecular Pharmacology

Volumn 86, Issue 2, 2014, Pages 231-242

  Chen, Yuanyuan ^a   Tang, Hong ^b   Seibel, William ^b   Papoian, Ruben ^b   Oh, Ki ^a   Li, Xiaoyu ^a   Zhang, Jianye ^a   Golczak, Marcin ^a   Palczewski, Krzysztof ^a   Kiser, Philip D ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTYL AMINOPEPTIDASE INHIBITOR; ENZYME INHIBITOR; GLUTAMYL AMINOPEPTIDASE; UNCLASSIFIED DRUG; ANGIOTENSIN II;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SPECIFICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDIAN EFFECTIVE CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; STRUCTURE ACTIVITY RELATION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; HYDROLYSIS; MAMMAL; METABOLISM; SF9 CELL LINE; SPODOPTERA;

ANGIOTENSIN II; ANIMALS; CATALYTIC DOMAIN; ENZYME INHIBITORS; GLUTAMYL AMINOPEPTIDASE; HUMANS; HYDROLYSIS; MAMMALS; SF9 CELLS; SPODOPTERA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84905964131     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.093070     Document Type: Article

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