Aminopeptidase A inhibitors as potential central antihypertensive agents

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 23, 1999, Pages 13415-13420

  Reaux, Annabelle ^a   Fournie Zaluski, Marie Claude ^a   David, Christelle ^a   Zini, Sylvie ^a   Roques, Bernard P ^a   Corvol, Pierre ^a   Llorens Cortes, Catherine ^a  

^a INSERM   (France)

Author keywords

Blood pressure; Brain; Mercapto inhibitors; Renin angiotensin system; Zinc metalloproteases

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 3 AMINO 4 MERCAPTOBUTYLSULFONIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN III; ANTIHYPERTENSIVE AGENT; ENZYME INHIBITOR; GLUTAMYL AMINOPEPTIDASE; LOSARTAN; MICROSOMAL AMINOPEPTIDASE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG TARGETING; ENZYME INHIBITION; HYPERTENSION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT;

AMINOPEPTIDASES; ANGIOTENSIN II; ANGIOTENSIN III; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BRAIN; ENZYME INHIBITORS; GLUTAMYL AMINOPEPTIDASE; INJECTIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; MALE; RATS; RATS, INBRED SHR;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0033539511     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.23.13415     Document Type: Article

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