X-ray crystal structure and specificity of the plasmodium falciparum malaria aminopeptidase PfM18AAP

Journal of Molecular Biology

Volumn 422, Issue 4, 2012, Pages 495-507

  Sivaraman, Komagal Kannan ^a   Oellig, Christine A ^a   Huynh, Kitmun ^a   Atkinson, Sarah C ^b,c   Poreba, Marcin ^d   Perugini, Matthew A ^b,c   Trenholme, Katharine R ^e,f   Gardiner, Donald L ^e   Salvesen, Guy ^g   Drag, Marcin ^d,g   Dalton, John P ^h,i   Whisstock, James C ^a   McGowan, Sheena ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

^d WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g BURNHAM INSTITUTE   (United States)

^h UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

ⁱ MCGILL UNIVERSITY   (Canada)

Author keywords

aminopeptidase; drug design; malaria; protease; structural biology

Indexed keywords

AMINOPEPTIDASE; PEPTIDE; PLASMODIUM FALCIPARUM MALARIA 18 AMINOPEPTIDASE; PROTEASOME; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

MAMMALIA; PLASMODIUM FALCIPARUM;

EID: 84865484501     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.06.006     Document Type: Article

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