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Volumn 29, Issue 5, 2013, Pages 2053-2057

Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose

Author keywords

2 deoxyglucose; Acute myelogenous leukemia; Carnitine; Glutathione; Glycolysis; Metabolome; Pentose phosphate pathway

Indexed keywords

ACETYLCARNITINE; CARNITINE; DEOXYGLUCOSE; GLUTATHIONE SYNTHASE; TRICARBOXYLIC ACID;

EID: 84876267967     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2299     Document Type: Article
Times cited : (33)

References (17)
  • 1
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O: On the origin of cancer cells. Science 123: 309-314, 1956.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 2
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • DOI 10.1038/nrc1478
    • Gatenby RA and Gillies RJ: Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899, 2004. (Pubitemid 39472955)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 3
    • 33746879141 scopus 로고    scopus 로고
    • Glycolysis inhibition for anticancer treatment
    • DOI 10.1038/sj.onc.1209597, PII 1209597
    • Pelicano H, Martin DS, Xu RH and Huang P: Glycolysis inhibition for anticancer treatment. Oncogene 25: 4633-4646, 2006. (Pubitemid 44187614)
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4633-4646
    • Pelicano, H.1    Martin, D.S.2    Xu, R.-H.3    Huang, P.4
  • 5
    • 0001477074 scopus 로고
    • Substrate specificity of brain hexokinase
    • Sols A and Crane RK: Substrate specificity of brain hexokinase. J Biol Chem 210: 581-595, 1954.
    • (1954) J Biol Chem , vol.210 , pp. 581-595
    • Sols, A.1    Crane, R.K.2
  • 6
    • 36749078674 scopus 로고    scopus 로고
    • Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation
    • DOI 10.1158/1535-7163.MCT-07-0310
    • Kurtoglu M, Gao N, Shang J, Maher JC, Lehrman MA, Wangpaichitr M, Savaraj N, Lane AN and Lampidis TJ: Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation. Mol Cancer Ther 6: 3049-3058, 2007. (Pubitemid 350206783)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.11 , pp. 3049-3058
    • Kurtoglu, M.1    Gao, N.2    Shang, J.3    Maher, J.C.4    Lehrman, M.A.5    Wangpaichitr, M.6    Savaraj, N.7    Lane, A.N.8    Lampidis, T.J.9
  • 7
    • 77949967131 scopus 로고    scopus 로고
    • Targeting metabolic transformation for cancer therapy
    • Tennant DA, Durán RV and Gottlieb E: Targeting metabolic transformation for cancer therapy. Nat Rev Cancer 10: 267-277, 2010.
    • (2010) Nat Rev Cancer , vol.10 , pp. 267-277
    • Tennant, D.A.1    Durán, R.V.2    Gottlieb, E.3
  • 9
    • 84863661689 scopus 로고    scopus 로고
    • Therapeutic targets in cancer cell metabolism and autophagy
    • Cheong H, Lu C, Lindsten T and Thompson CB: Therapeutic targets in cancer cell metabolism and autophagy. Nat Biotechnol 30: 671-678, 2012.
    • (2012) Nat Biotechnol , vol.30 , pp. 671-678
    • Cheong, H.1    Lu, C.2    Lindsten, T.3    Thompson, C.B.4
  • 10
    • 1642494855 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose Increases the Efficacy of Adriamycin and Paclitaxel in Human Osteosarcoma and Non-Small Cell Lung Cancers in Vivo
    • DOI 10.1158/0008-5472.CAN-03-3294
    • Maschek G, Savaraj N, Priebe W, Braunschweiger P, Hamilton K, Tidmarsh GF, De Young LR and Lampidis TJ: 2-Deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res 64: 31-34, 2004. (Pubitemid 38114078)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 31-34
    • Maschek, G.1    Savaraj, N.2    Priebe, W.3    Braunschweiger, P.4    Hamilton, K.5    Tidmarsh, G.F.6    De Young, L.R.7    Lampidis, T.J.8
  • 12
    • 79952679120 scopus 로고    scopus 로고
    • Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia
    • Ooga T, Sato H, Nagashima A, Sasaki K, Tomita M, Soga T and Ohashi Y: Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia. Mol Biosyst 7: 1217-1223, 2011.
    • (2011) Mol Biosyst , vol.7 , pp. 1217-1223
    • Ooga, T.1    Sato, H.2    Nagashima, A.3    Sasaki, K.4    Tomita, M.5    Soga, T.6    Ohashi, Y.7
  • 14
    • 0026459805 scopus 로고
    • 31P NMR and metabolic implications
    • 31P NMR and metabolic implications. Biochimie 74: 867-873, 1992.
    • (1992) Biochimie , vol.74 , pp. 867-873
    • Chen, W.1    Guéron, M.2
  • 15
  • 16
    • 0036864358 scopus 로고    scopus 로고
    • Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
    • DOI 10.1042/BST0301064
    • Hardie DG and Pan DA: Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase. Biochem Soc Trans 30: 1064-1070, 2002. (Pubitemid 36002407)
    • (2002) Biochemical Society Transactions , vol.30 , Issue.6 , pp. 1064-1070
    • Hardie, D.G.1    Pan, D.A.2
  • 17
    • 84863763440 scopus 로고    scopus 로고
    • AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
    • Jeon SM, Chandel NS and Hay N: AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature 485: 661-665, 2012.
    • (2012) Nature , vol.485 , pp. 661-665
    • Jeon, S.M.1    Chandel, N.S.2    Hay, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.