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Volumn 33, Issue 5, 2014, Pages 428-440

Ovarian cancer biology and immunotherapy

Author keywords

DC vaccines; Experimental models; Immunotherapy; Ovarian cancer; Tumor microenvironment

Indexed keywords

CARCINOGEN; DENDRITIC CELL VACCINE; INTERLEUKIN 10; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; CYTOKINE;

EID: 84905862971     PISSN: 08830185     EISSN: 15635244     Source Type: Journal    
DOI: 10.3109/08830185.2014.921161     Document Type: Review
Times cited : (28)

References (93)
  • 3
    • 33845212719 scopus 로고    scopus 로고
    • Carcinoma of the ovary. FIGO26th annual report on the results of treatment in gynecological cancer
    • Heintz AP,Odicino F,Maisonneuve P, et al. Carcinoma of the ovary. FIGO26th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 2006;95(Suppl 1):S161-S192
    • (2006) Int J Gynaecol Obstet , vol.95 , Issue.SUPPL. 1 , pp. S161-S192
    • Heintz, A.P.1    Odicino, F.2    Maisonneuve, P.3
  • 4
    • 78650223296 scopus 로고    scopus 로고
    • Microenvironment and pathogenesis of epithelial ovarian cancer
    • Saad AF, Hu W, Sood AK. Microenvironment and pathogenesis of epithelial ovarian cancer. Horm Cancer 2010;1(6):277-290
    • (2010) Horm Cancer , vol.1 , Issue.6 , pp. 277-290
    • Saad, A.F.1    Hu, W.2    Sood, A.K.3
  • 5
    • 0037448353 scopus 로고    scopus 로고
    • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
    • Zhang L, Conejo-Garcia JR, Katsaros D, et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl JMed 2003;348(3):203-213
    • (2003) N. Engl J. Med , vol.348 , Issue.3 , pp. 203-213
    • Zhang, L.1    Conejo-Garcia, J.R.2    Katsaros, D.3
  • 6
    • 79952612330 scopus 로고    scopus 로고
    • Dendritic cell vaccination against ovarian cancer-tipping the Treg/TH17 balance to therapeutic advantage?
    • Cannon MJ, Goyne H, Stone PJ, Chiriva-Internati M. Dendritic cell vaccination against ovarian cancer-tipping the Treg/TH17 balance to therapeutic advantage? Expert Opin Biol Ther 2011;11(4):441-445
    • (2011) Expert Opin Biol Ther , vol.11 , Issue.4 , pp. 441-445
    • Cannon, M.J.1    Goyne, H.2    Stone, P.J.3    Chiriva-Internati, M.4
  • 7
    • 0017684192 scopus 로고
    • Incidence of the histologic types of ovarian cancer: The U.S. Third national cancer survey 1969 1971
    • Weiss NS, Homonchuk T, Young JL, Jr. Incidence of the histologic types of ovarian cancer: The U.S. Third National Cancer Survey, 1969-1971. Gynecol Oncol 1977;5(2):161-167
    • (1977) Gynecol Oncol , vol.5 , Issue.2 , pp. 161-167
    • Weiss, N.S.1    Homonchuk, T.2    Young, J.L.3
  • 9
    • 0030472570 scopus 로고    scopus 로고
    • Microscopic benign and invasivemalignant neoplasms and a cancer-prone phenotype in prophylactic oophorectomies
    • Salazar H, Godwin AK, DalyMB, et al.Microscopic benign and invasivemalignant neoplasms and a cancer-prone phenotype in prophylactic oophorectomies. J Natl Cancer Inst 1996;88(24):1810-1820
    • (1996) J Natl Cancer Inst , vol.88 , Issue.24 , pp. 1810-1820
    • Salazar, H.1    Godwin, A.K.2    Daly, M.B.3
  • 10
    • 0015230305 scopus 로고
    • Incessant ovulation-A factor in ovarian neoplasia?
    • Fathalla MF. Incessant ovulation-a factor in ovarian neoplasia? Lancet 1971;2(7716):163
    • (1971) Lancet , vol.2 , Issue.7716 , pp. 163
    • Fathalla, M.F.1
  • 12
    • 0029816209 scopus 로고    scopus 로고
    • Epithelial ovarian cancer risk among women with polycystic ovary syndrome
    • Schildkraut JM, Schwingl PJ, Bastos E, et al. Epithelial ovarian cancer risk among women with polycystic ovary syndrome. Obstet Gynecol 1996;88(4 Pt 1):554-559
    • (1996) Obstet Gynecol , vol.88 , Issue.4 PART 1 , pp. 554-559
    • Schildkraut, J.M.1    Schwingl, P.J.2    Bastos, E.3
  • 13
    • 0032477328 scopus 로고    scopus 로고
    • Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone
    • Risch HA. Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone. J Natl Cancer Inst 1998;90(23):1774-1786
    • (1998) J Natl Cancer Inst , vol.90 , Issue.23 , pp. 1774-1786
    • Risch, H.A.1
  • 14
    • 0033199807 scopus 로고    scopus 로고
    • Possible role of ovarian epithelial inflammation in ovarian cancer
    • Ness RB, Cottreau C. Possible role of ovarian epithelial inflammation in ovarian cancer. JNatl Cancer Inst 1999;91(17):1459-1467
    • (1999) JNatl Cancer Inst , vol.91 , Issue.17 , pp. 1459-1467
    • Ness, R.B.1    Cottreau, C.2
  • 15
    • 3142717392 scopus 로고    scopus 로고
    • NF-kappaB, macrophage migration inhibitory factor and cyclooxygenaseinhibitions as likelymechanisms behind the acetaminophen- and NSAID-prevention of the ovarian cancer
    • Altinoz MA, Korkmaz R. NF-kappaB, macrophage migration inhibitory factor and cyclooxygenaseinhibitions as likelymechanisms behind the acetaminophen- and NSAID-prevention of the ovarian cancer. Neoplasma 2004;51(4):239-247
    • (2004) Neoplasma , vol.51 , Issue.4 , pp. 239-247
    • Altinoz, M.A.1    Korkmaz, R.2
  • 16
    • 34248574353 scopus 로고    scopus 로고
    • Ovarian cancer and hormone replacement therapy in the million women study
    • Beral V, Bull D, Green J, Reeves G. Ovarian cancer and hormone replacement therapy in theMillion Women Study. Lancet 2007;369(9574):1703-1710
    • (2007) Lancet , vol.369 , Issue.9574 , pp. 1703-1710
    • Beral, V.1    Bull, D.2    Green, J.3    Reeves, G.4
  • 17
    • 0035884589 scopus 로고    scopus 로고
    • Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal andmalignant human ovarian surface epithelial cells
    • Syed V, Ulinski G, Mok SC, et al. Expression of gonadotropin receptor and growth responses to key reproductive hormones in normal andmalignant human ovarian surface epithelial cells. Cancer Res 2001;61(18):6768-6776
    • (2001) Cancer Res , vol.61 , Issue.18 , pp. 6768-6776
    • Syed, V.1    Ulinski, G.2    Mok, S.C.3
  • 19
    • 20844462886 scopus 로고    scopus 로고
    • Polycystic ovary syndrome and gynecological cancers: Is there a link?
    • Gadducci A, Gargini A, Palla E, et al. Polycystic ovary syndrome and gynecological cancers: Is there a link? Gynecol Endocrinol 2005;20(4):200-208
    • (2005) Gynecol Endocrinol , vol.20 , Issue.4 , pp. 200-208
    • Gadducci, A.1    Gargini, A.2    Palla, E.3
  • 20
    • 60149089809 scopus 로고    scopus 로고
    • A case-control study of oral contraceptive use and incident breast cancer
    • Rosenberg L, Zhang Y, Coogan PF, et al. A case-control study of oral contraceptive use and incident breast cancer. Am J Epidemiol 2009;169(4):473-479
    • (2009) Am J Epidemiol , vol.169 , Issue.4 , pp. 473-479
    • Rosenberg, L.1    Zhang, Y.2    Coogan, P.F.3
  • 21
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12(4):252-264
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1
  • 22
    • 17444447873 scopus 로고    scopus 로고
    • Apoptosis and apoptosis-related proteins (fas, fas ligand, blc-2, p53) in lymphoid elements of human ovarian tumors
    • Ben-Hur H, Gurevich P, Huszar M, et al. Apoptosis and apoptosis-related proteins (Fas, Fas ligand, Blc-2, p53) in lymphoid elements of human ovarian tumors. Eur J Gynaecol Oncol 2000;21(1): 53-57
    • (2000) Eur J Gynaecol Oncol , vol.21 , Issue.1 , pp. 53-57
    • Ben-Hur, H.1    Gurevich, P.2    Huszar, M.3
  • 23
    • 13144265726 scopus 로고    scopus 로고
    • HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance
    • Paul P, Rouas-Freiss N, Khalil-Daher I, et al. HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci U S A 1998;95(8):4510-4515
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.8 , pp. 4510-4515
    • Paul, P.1    Rouas-Freiss, N.2    Khalil-Daher, I.3
  • 24
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392(6673): 245-252
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 25
    • 0141629819 scopus 로고    scopus 로고
    • Role of plasmacytoid dendritic cells in immunity and tolerance after allogeneic hematopoietic stem cell transplantation
    • Arpinati M, Chirumbolo G, Urbini B, et al. Role of plasmacytoid dendritic cells in immunity and tolerance after allogeneic hematopoietic stem cell transplantation. Transpl Immunol 2003;11(3-4):345-356
    • (2003) Transpl Immunol , vol.11 , Issue.3-4 , pp. 345-356
    • Arpinati, M.1    Chirumbolo, G.2    Urbini, B.3
  • 26
    • 75749138095 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Key players in the initiation and regulation of immune responses
    • Lande R, Gilliet M. Plasmacytoid dendritic cells: Key players in the initiation and regulation of immune responses. Ann N Y Acad Sci 2010;1183:89-103
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 89-103
    • Lande, R.1    Gilliet, M.2
  • 27
    • 2542467747 scopus 로고    scopus 로고
    • A cell-surface molecule selectively expressed on murine natural interferon-producing cells that blocks secretion of interferon-alpha
    • Blasius A, Vermi W, Krug A, et al. A cell-surface molecule selectively expressed on murine natural interferon-producing cells that blocks secretion of interferon-alpha. Blood 2004;103(11):4201-4206
    • (2004) Blood , vol.103 , Issue.11 , pp. 4201-4206
    • Blasius, A.1    Vermi, W.2    Krug, A.3
  • 28
    • 33644772437 scopus 로고    scopus 로고
    • Siglec-H is an IPC-specific receptor thatmodulates type i IFN secretion through DAP12
    • Blasius AL, Cella M,Maldonado J, et al. Siglec-H is an IPC-specific receptor thatmodulates type I IFN secretion through DAP12. Blood 2006;107(6):2474-2476
    • (2006) Blood , vol.107 , Issue.6 , pp. 2474-2476
    • Blasius, A.L.1    Cella, M.2    Maldonado, J.3
  • 29
    • 3242754954 scopus 로고    scopus 로고
    • Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules
    • Yoneyama H, Matsuno K, Zhang Y, et al. Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. Int Immunol 2004;16(7):915-928
    • (2004) Int Immunol , vol.16 , Issue.7 , pp. 915-928
    • Yoneyama, H.1    Matsuno, K.2    Zhang, Y.3
  • 30
    • 10844268751 scopus 로고    scopus 로고
    • Chemokine-like receptor 1 expression and chemerin-directed chemotaxis distinguish plasmacytoid from myeloid dendritic cells in human blood
    • Zabel BA, Silverio AM, Butcher EC. Chemokine-like receptor 1 expression and chemerin-directed chemotaxis distinguish plasmacytoid from myeloid dendritic cells in human blood. J Immunol 2005;174(1):244-251
    • (2005) J Immunol , vol.174 , Issue.1 , pp. 244-251
    • Zabel, B.A.1    Silverio, A.M.2    Butcher, E.C.3
  • 31
    • 0042385124 scopus 로고    scopus 로고
    • The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12
    • Vanbervliet B, Bendriss-Vermare N, Massacrier C, et al. The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12. J. Exp. Med 2003;198(5):823-830
    • (2003) J. Exp. Med , vol.198 , Issue.5 , pp. 823-830
    • Vanbervliet, B.1    Bendriss-Vermare, N.2    Massacrier, C.3
  • 32
    • 0033546053 scopus 로고    scopus 로고
    • The nature of the principal type 1 interferon-producing cells in human blood
    • Siegal FP, Kadowaki N, Shodell M, et al.The nature of the principal type 1 interferon-producing cells in human blood. Science 1999;284(5421):1835-1837
    • (1999) Science , vol.284 , Issue.5421 , pp. 1835-1837
    • Siegal, F.P.1    Kadowaki, N.2    Shodell, M.3
  • 33
    • 33846438598 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand
    • Ito T, YangM,Wang YH, et al. Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. J. Exp. Med 2007;204(1):105-115
    • (2007) J. Exp. Med , vol.204 , Issue.1 , pp. 105-115
    • Ito, T.1    Yang, M.2    Wang, Y.H.3
  • 34
    • 44649189089 scopus 로고    scopus 로고
    • Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery
    • Ito T, Hanabuchi S, Wang YH, et al. Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity 2008;28(6):870-880
    • (2008) Immunity , vol.28 , Issue.6 , pp. 870-880
    • Ito, T.1    Hanabuchi, S.2    Wang, Y.H.3
  • 35
    • 84886944946 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells and regulatory T cells in the tumormicroenvironment: A dangerous liaison
    • Conrad C, Gilliet M. Plasmacytoid dendritic cells and regulatory T cells in the tumormicroenvironment: A dangerous liaison. Oncoimmunology 2013;2(5):e23887
    • (2013) Oncoimmunology , vol.2 , Issue.5 , pp. e23887
    • Conrad, C.1    Gilliet, M.2
  • 36
    • 51349158548 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells mediate oral tolerance
    • Goubier A, Dubois B, Gheit H, et al. Plasmacytoid dendritic cells mediate oral tolerance. Immunity 2008;29(3):464-475
    • (2008) Immunity , vol.29 , Issue.3 , pp. 464-475
    • Goubier, A.1    Dubois, B.2    Gheit, H.3
  • 37
    • 33646676046 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus
    • Smit JJ, Rudd BD, Lukacs NW. Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus. J. Exp. Med 2006;203(5):1153-1159
    • (2006) J. Exp. Med , vol.203 , Issue.5 , pp. 1153-1159
    • Smit, J.J.1    Rudd, B.D.2    Lukacs, N.W.3
  • 38
    • 77950189167 scopus 로고    scopus 로고
    • Ovarian cancer creates a suppressive microenvironment to escape immune elimination
    • Yigit R, Massuger LF, Figdor CG, Torensma R. Ovarian cancer creates a suppressive microenvironment to escape immune elimination. Gynecol Oncol 2010;117(2):366-372
    • (2010) Gynecol Oncol , vol.117 , Issue.2 , pp. 366-372
    • Yigit, R.1    Massuger, L.F.2    Figdor, C.G.3    Torensma, R.4
  • 39
    • 34848915783 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells from mouse tumordraining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
    • Sharma MD, Baban B, Chandler P, et al. Plasmacytoid dendritic cells from mouse tumordraining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest 2007;117(9):2570-2582
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2570-2582
    • Sharma, M.D.1    Baban, B.2    Chandler, P.3
  • 40
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells:more of the same or a division of labor?
    • Curotto de Lafaille MA, Lafaille JJ. Natural and adaptive foxp3+ regulatory T cells:more of the same or a division of labor? Immunity 2009;30(5):626-635
    • (2009) Immunity , vol.30 , Issue.5 , pp. 626-635
    • De Lafaille Ma, C.1    Lafaille, J.J.2
  • 41
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997;389(6652):737-742
    • (1997) Nature , vol.389 , Issue.6652 , pp. 737-742
    • Groux, H.1    O'garra, A.2    Bigler, M.3
  • 42
    • 0346996879 scopus 로고    scopus 로고
    • The regulatoryTcell family: Distinct subsets andtheir interrelations
    • Jonuleit H, SchmittE.The regulatoryTcell family: Distinct subsets andtheir interrelations. J. Immunol 2003;171(12):6323-6327
    • (2003) J. Immunol , vol.171 , Issue.12 , pp. 6323-6327
    • Jonuleit, H.1    Schmitt, E.2
  • 43
    • 84878632550 scopus 로고    scopus 로고
    • What are the molecules involved in regulatory T cells induction by dendritic cells in cancer?
    • Ramos RN, de Moraes CJ, Zelante B, Barbuto JA. What are the molecules involved in regulatory Tcells induction by dendritic cells in cancer? Clin Dev Immunol 2013;2013:806025
    • (2013) Clin Dev Immunol , vol.2013 , pp. 806025
    • Ramos, R.N.1    De Moraes, C.J.2    Zelante, B.3    Barbuto, J.A.4
  • 44
    • 29444442811 scopus 로고    scopus 로고
    • Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
    • Sato E, Olson SH, Ahn J, et al. Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci U S A 2005;102(51):18538-18543
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.51 , pp. 18538-18543
    • Sato, E.1    Olson, S.H.2    Ahn, J.3
  • 45
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 2004;10(9):942-949
    • (2004) Nat. Med , vol.10 , Issue.9 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 46
    • 34548798737 scopus 로고    scopus 로고
    • Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma
    • Kryczek I, Wei S, Zhu G, et al. Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma. Cancer Res 2007;67(18):8900-8905
    • (2007) Cancer Res , vol.67 , Issue.18 , pp. 8900-8905
    • Kryczek, I.1    Wei, S.2    Zhu, G.3
  • 47
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299(5609):1057-1061
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 48
    • 0035658072 scopus 로고    scopus 로고
    • Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells
    • ZouW,Machelon V, Coulomb-L'Hermin A, et al. Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nat. Med 2001;7(12):1339-1346
    • (2001) Nat. Med , vol.7 , Issue.12 , pp. 1339-1346
    • Zou, W.1    MacHelon, V.2    Coulomb-L'hermin, A.3
  • 49
    • 0028929803 scopus 로고
    • Angiogenesis in cancer vascular,rheumatoid andotherdisease
    • Folkman J. Angiogenesis in cancer, vascular,rheumatoid andotherdisease.Nat. Med 1995;1(1):27-31
    • (1995) Nat. Med , vol.1 , Issue.1 , pp. 27-31
    • Folkman, J.1
  • 50
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman J. The role of angiogenesis in tumor growth. Semin Cancer Biol 1992;3(2):65-71
    • (1992) Semin Cancer Biol , vol.3 , Issue.2 , pp. 65-71
    • Folkman, J.1
  • 51
    • 33846933952 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) pathway as a therapeutic target in gynecologicmalignancies
    • Frumovitz M, Sood AK. Vascular endothelial growth factor (VEGF) pathway as a therapeutic target in gynecologicmalignancies. Gynecol Oncol 2007;104(3):768-778
    • (2007) Gynecol Oncol , vol.104 , Issue.3 , pp. 768-778
    • Frumovitz, M.1    Sood, A.K.2
  • 52
    • 33745890935 scopus 로고    scopus 로고
    • Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer
    • Lokshin AE, Winans M, Landsittel D, et al. Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer. Gynecol Oncol 2006;102(2):244-251
    • (2006) Gynecol Oncol , vol.102 , Issue.2 , pp. 244-251
    • Lokshin, A.E.1    Winans, M.2    Landsittel, D.3
  • 53
    • 0042922958 scopus 로고    scopus 로고
    • Alpha V-and beta1-integrin subunits are commonly expressed inmalignant effusions fromovarian carcinoma patients
    • Davidson B,Goldberg I, Reich R, et al. AlphaV- and beta1-integrin subunits are commonly expressed inmalignant effusions fromovarian carcinoma patients. Gynecol Oncol 2003;90(2):248-257
    • (2003) Gynecol Oncol , vol.90 , Issue.2 , pp. 248-257
    • Davidson, B.1    Goldberg, I.2    Reich, R.3
  • 54
    • 4143123295 scopus 로고    scopus 로고
    • EphA2 expression is associated with aggressive features in ovarian carcinoma
    • Thaker PH, Deavers M, Celestino J, et al. EphA2 expression is associated with aggressive features in ovarian carcinoma. Clin Cancer Res 2004;10(15):5145-5150
    • (2004) Clin Cancer Res , vol.10 , Issue.15 , pp. 5145-5150
    • Thaker, P.H.1    Deavers, M.2    Celestino, J.3
  • 55
    • 84881141826 scopus 로고    scopus 로고
    • Angiogenesis-related pathways in the pathogenesis of ovarian cancer
    • Gavalas NG, Liontos M, Trachana SP, et al. Angiogenesis-related pathways in the pathogenesis of ovarian cancer. Int JMol Sci 2013;14(8):15885-15909
    • (2013) Int JMol Sci , vol.14 , Issue.8 , pp. 15885-15909
    • Gavalas, N.G.1    Liontos, M.2    Trachana, S.P.3
  • 56
    • 33845343558 scopus 로고    scopus 로고
    • Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy
    • Li B, Lalani AS, Harding TC, et al. Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy. Clin Cancer Res 2006;12(22):6808-6816
    • (2006) Clin Cancer Res , vol.12 , Issue.22 , pp. 6808-6816
    • Li, B.1    Lalani, A.S.2    Harding, T.C.3
  • 57
    • 84879823068 scopus 로고    scopus 로고
    • The plasma concentration of VEGF, HE4 and CA125 as a new biomarkers panel in different stages and sub-types of epithelial ovarian tumors
    • Lawicki S, Bedkowska GE, Gacuta-Szumarska E, SzmitkowskiM.The plasma concentration of VEGF, HE4 and CA125 as a new biomarkers panel in different stages and sub-types of epithelial ovarian tumors. J Ovarian Res 2013;6(1):45
    • (2013) J Ovarian Res , vol.6 , Issue.1 , pp. 45
    • Lawicki, S.1    Bedkowska, G.E.2    Gacuta-Szumarska, E.3    Szmitkowski, M.4
  • 58
    • 0036855198 scopus 로고    scopus 로고
    • Early events in ovarian epithelial carcinogenesis: Progress and problems in experimental approaches
    • Auersperg N, Ota T, Mitchell GW. Early events in ovarian epithelial carcinogenesis: Progress and problems in experimental approaches. Int J Gynecol Cancer 2002;12(6):691-703
    • (2002) Int J Gynecol Cancer , vol.12 , Issue.6 , pp. 691-703
    • Auersperg, N.1    Ota, T.2    Mitchell, G.W.3
  • 59
    • 0021220668 scopus 로고
    • 7,12-Dimethylbenz[a]anthracene-DNA adducts in sprague-dawley and long-evans female rats: The relationship of DNA adducts to mammary cancer
    • Daniel FB, Joyce NJ. 7,12-Dimethylbenz[a]anthracene-DNA adducts in Sprague-Dawley and Long-Evans female rats: The relationship of DNA adducts to mammary cancer. Carcinogenesis 1984;5(8):1021-1026
    • (1984) Carcinogenesis , vol.5 , Issue.8 , pp. 1021-1026
    • Daniel, F.B.1    Joyce, N.J.2
  • 60
    • 0032169058 scopus 로고    scopus 로고
    • Histologic characterization of rat ovarian carcinoma induced by intraovarian insertion of a 712-dimethylbenz[a]anthracene-coated suture: Common epithelial tumors of the ovary in rats?
    • Nishida T, Sugiyama T,Kataoka A, et al.Histologic characterization of rat ovarian carcinoma induced by intraovarian insertion of a 7,12-dimethylbenz[a]anthracene-coated suture: Common epithelial tumors of the ovary in rats? Cancer 1998;83(5):965-970
    • (1998) Cancer , vol.83 , Issue.5 , pp. 965-970
    • Nishida, T.1    Sugiyama, T.2    Kataoka, A.3
  • 61
    • 0036739915 scopus 로고    scopus 로고
    • Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation
    • Buters JT, Mahadevan B, Quintanilla-Martinez L, et al. Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation. Chem Res Toxicol 2002;15(9):1127-1135
    • (2002) Chem Res Toxicol , vol.15 , Issue.9 , pp. 1127-1135
    • Buters, J.T.1    Mahadevan, B.2    Quintanilla-Martinez, L.3
  • 62
    • 33745240064 scopus 로고    scopus 로고
    • Effect of duration of dosing on onset of ovarian failure in a chemical-inducedmouse model of perimenopause
    • Lohff JC, Christian PJ, Marion SL, Hoyer PB. Effect of duration of dosing on onset of ovarian failure in a chemical-inducedmouse model of perimenopause.Menopause 2006;13(3):482-488
    • (2006) Menopause , vol.13 , Issue.3 , pp. 482-488
    • Lohff, J.C.1    Christian, P.J.2    Marion, S.L.3    Hoyer, P.B.4
  • 63
    • 60449106104 scopus 로고    scopus 로고
    • Ovarian neoplasm development by 7,12- dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian failure
    • Hoyer PB, Davis JR, Bedrnicek JB, et al. Ovarian neoplasm development by 7,12- dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian failure. Gynecol Oncol 2009;112(3):610-615
    • (2009) Gynecol Oncol , vol.112 , Issue.3 , pp. 610-615
    • Hoyer, P.B.1    Davis, J.R.2    Bedrnicek, J.B.3
  • 64
    • 77749239978 scopus 로고    scopus 로고
    • 712-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries ofmice treated with 4-vinylcyclohexene diepoxide
    • Craig ZR, Davis JR,Marion SL, et al. 7,12-dimethylbenz[a]anthracene induces sertoli-leydig-cell tumors in the follicle-depleted ovaries ofmice treated with 4-vinylcyclohexene diepoxide. CompMed 2010;60(1):10-17
    • (2010) Comp. Med , vol.60 , Issue.1 , pp. 10-17
    • Craig, Z.R.1    Davis, J.R.2    Marion, S.L.3
  • 65
    • 0036463949 scopus 로고    scopus 로고
    • Induction of ovarian cancer by definedmultiple genetic changes in amouse model system
    • Orsulic S, Li Y, Soslow RA, et al. Induction of ovarian cancer by definedmultiple genetic changes in amouse model system. Cancer Cell 2002;1(1):53-62
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 53-62
    • Orsulic, S.1    Li, Y.2    Soslow, R.A.3
  • 66
    • 0037444396 scopus 로고    scopus 로고
    • Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer
    • Connolly DC, Bao R, Nikitin AY, et al. Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer. Cancer Res 2003;63(6):1389-1397
    • (2003) Cancer Res , vol.63 , Issue.6 , pp. 1389-1397
    • Connolly, D.C.1    Bao, R.2    Nikitin, A.Y.3
  • 67
    • 13444269246 scopus 로고    scopus 로고
    • Role of K-ras and Pten in the development ofmouse models of endometriosis and endometrioid ovarian cancer
    • Dinulescu DM, Ince TA, Quade BJ, et al. Role of K-ras and Pten in the development ofmouse models of endometriosis and endometrioid ovarian cancer. Nat. Med 2005;11(1):63-70
    • (2005) Nat. Med , vol.11 , Issue.1 , pp. 63-70
    • Dinulescu, D.M.1    Ince, T.A.2    Quade, B.J.3
  • 68
    • 34047171574 scopus 로고    scopus 로고
    • Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the wnt/beta-catenin and PI3K/Pten signaling pathways
    • Wu R, Hendrix-Lucas N, Kuick R, et al. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell 2007;11(4):321-333
    • (2007) Cancer Cell , vol.11 , Issue.4 , pp. 321-333
    • Wu, R.1    Hendrix-Lucas, N.2    Kuick, R.3
  • 69
    • 77949493130 scopus 로고    scopus 로고
    • Induction of ovarian leiomyosarcomas in mice by conditional inactivation of brca1 and p53
    • Quinn BA, Brake T, Hua X, et al. Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53. PloS One 2009;4(12):e8404
    • (2009) PloS One , vol.4 , Issue.12 , pp. e8404
    • Quinn, B.A.1    Brake, T.2    Hua, X.3
  • 70
    • 84857612237 scopus 로고    scopus 로고
    • Ovarian cancer: Etiology, risk factors, and epidemiology
    • Hunn J, RodriguezGC. Ovarian cancer: Etiology, risk factors, and epidemiology. ClinObstetGynecol 2012;55(1):3-23
    • (2012) ClinObstetGynecol , vol.55 , Issue.1 , pp. 3-23
    • Hunn, J.1    Rodriguez, G.C.2
  • 71
    • 84856527983 scopus 로고    scopus 로고
    • An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice
    • Kinross KM, Montgomery KG, Kleinschmidt M, et al. An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice. J Clin Invest 2012;122(2):553-557
    • (2012) J Clin Invest , vol.122 , Issue.2 , pp. 553-557
    • Kinross, K.M.1    Montgomery, K.G.2    Kleinschmidt, M.3
  • 72
    • 0034054990 scopus 로고    scopus 로고
    • Development of a syngeneic mousemodel for events related to ovarian cancer
    • Roby KF, Taylor CC, Sweetwood JP, et al.Development of a syngeneic mousemodel for events related to ovarian cancer. Carcinogenesis 2000;21(4):585-591
    • (2000) Carcinogenesis , vol.21 , Issue.4 , pp. 585-591
    • Roby, K.F.1    Taylor, C.C.2    Sweetwood, J.P.3
  • 73
    • 0036899148 scopus 로고    scopus 로고
    • Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma
    • Zhang L, Yang N, Garcia JR, et al. Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma. Am J Pathol 2002;161(6):2295-2309
    • (2002) Am J Pathol , vol.161 , Issue.6 , pp. 2295-2309
    • Zhang, L.1    Yang, N.2    Garcia, J.R.3
  • 74
    • 33746705594 scopus 로고    scopus 로고
    • Comparison of ID8 MOSE and VEGFmodified ID8cell lines in an immunocompetent animal model for human ovarian cancer
    • Janat-Amsbury MM, Yockman JW, Anderson ML, et al. Comparison of ID8 MOSE and VEGFmodified ID8cell lines in an immunocompetent animal model for human ovarian cancer.Anticancer Res 2006;26(4B):2785-2789
    • (2006) Anticancer Res , vol.26 , Issue.4 , pp. 2785-2789
    • Janat-Amsbury, M.M.1    Yockman, J.W.2    Anderson, M.L.3
  • 75
    • 84876749671 scopus 로고    scopus 로고
    • Characterization and evaluation of pre-clinical suitability of a syngeneic orthotopicmouse ovarian cancermodel
    • Cho S, Sun Y, Soisson AP, et al. Characterization and evaluation of pre-clinical suitability of a syngeneic orthotopicmouse ovarian cancermodel. Anticancer Res 2013;33(4):1317-1324
    • (2013) Anticancer Res , vol.33 , Issue.4 , pp. 1317-1324
    • Cho, S.1    Sun, Y.2    Soisson, A.P.3
  • 76
    • 84876699831 scopus 로고    scopus 로고
    • Past present and future strategies of immunotherapy in gynecologicalmalignancies
    • Bellati F, Napoletano C, Ruscito I, et al. Past, present and future strategies of immunotherapy in gynecologicalmalignancies. CurrMolMed 2013;13(4):648-669
    • (2013) Curr. Mol. Med , vol.13 , Issue.4 , pp. 648-669
    • Bellati, F.1    Napoletano, C.2    Ruscito, I.3
  • 77
    • 0033017065 scopus 로고    scopus 로고
    • A Phase i study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen
    • Morse MA, Deng Y, Coleman D, et al. A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen. Clin Cancer Res 1999;5(6):1331-1338
    • (1999) Clin Cancer Res , vol.5 , Issue.6 , pp. 1331-1338
    • Morse, M.A.1    Deng, Y.2    Coleman, D.3
  • 79
    • 0036080196 scopus 로고    scopus 로고
    • Novel immunotherapeutic strategies in gynecologic oncology. Dendritic cell-based immunotherapy for ovarian cancer
    • Santin AD, Bellone S, Underwood LJ, et al. Novel immunotherapeutic strategies in gynecologic oncology. Dendritic cell-based immunotherapy for ovarian cancer. Minerva Ginecol 2002;54(2):133-144
    • (2002) Minerva Ginecol , vol.54 , Issue.2 , pp. 133-144
    • Santin, A.D.1    Bellone, S.2    Underwood, L.J.3
  • 80
    • 0034331218 scopus 로고    scopus 로고
    • Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
    • Brossart P, Wirths S, Stuhler G, et al. Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells. Blood 2000;96(9):3102-3108
    • (2000) Blood , vol.96 , Issue.9 , pp. 3102-3108
    • Brossart, P.1    Wirths, S.2    Stuhler, G.3
  • 81
    • 0036181959 scopus 로고    scopus 로고
    • Vaccinationwith autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: Clinical and immunological evaluation of a phase i trial
    • Hernando JJ, Park TW, Kubler K, et al. Vaccinationwith autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: Clinical and immunological evaluation of a phase I trial. Cancer Immunol Immunother 2002;51(1):45-52
    • (2002) Cancer Immunol Immunother , vol.51 , Issue.1 , pp. 45-52
    • Hernando, J.J.1    Park, T.W.2    Kubler, K.3
  • 82
    • 32944475905 scopus 로고    scopus 로고
    • Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase i trial in patients with adenocarcinoma
    • Loveland BE, Zhao A,White S, et al.Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase I trial in patients with adenocarcinoma. Clin Cancer Res 2006;12(3 Pt 1):869-877
    • (2006) Clin Cancer Res , vol.12 , Issue.3 PART 1 , pp. 869-877
    • Loveland, B.E.1    Zhao, A.2    White, S.3
  • 83
    • 34247218172 scopus 로고    scopus 로고
    • Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer
    • Hernando JJ, Park TW, Fischer HP, et al. Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer. Lancet Oncol 2007;8(5):451-454
    • (2007) Lancet Oncol , vol.8 , Issue.5 , pp. 451-454
    • Hernando, J.J.1    Park, T.W.2    Fischer, H.P.3
  • 84
    • 70349456786 scopus 로고    scopus 로고
    • A phase i trial of immunotherapy with lapuleucel-T (APC8024) in patients with refractory metastatic tumors that express HER-2/neu
    • Peethambaram PP, Melisko ME, Rinn KJ, et al. A phase I trial of immunotherapy with lapuleucel-T (APC8024) in patients with refractory metastatic tumors that express HER-2/neu. Clin Cancer Res 2009;15(18):5937-5944
    • (2009) Clin Cancer Res , vol.15 , Issue.18 , pp. 5937-5944
    • Peethambaram, P.P.1    Melisko, M.E.2    Rinn, K.J.3
  • 85
    • 84883466843 scopus 로고    scopus 로고
    • A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: From bench to bedside
    • Chiang CL, Kandalaft LE, Tanyi J, et al. A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: From bench to bedside. Clin Cancer Res 2013;19(17):4801-4815
    • (2013) Clin Cancer Res , vol.19 , Issue.17 , pp. 4801-4815
    • Chiang, C.L.1    Kandalaft, L.E.2    Tanyi, J.3
  • 86
    • 84874625308 scopus 로고    scopus 로고
    • Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer
    • Kandalaft LE, Powell DJ, Jr., Chiang CL, et al. Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer. Oncoimmunology 2013;2(1):e22664
    • (2013) Oncoimmunology , vol.2 , Issue.1 , pp. e22664
    • Kandalaft, L.E.1    Powell, D.J.2    Chiang, C.L.3
  • 90
    • 84884503883 scopus 로고    scopus 로고
    • Morbidity of surgery after neoadjuvant chemotherapy including bevacizumab for advanced ovarian cancer
    • Chereau E, Lambaudie E, Houvenaeghel G. Morbidity of surgery after neoadjuvant chemotherapy including bevacizumab for advanced ovarian cancer. Int J Gynecol Cancer 2013;23(7):1326-1330
    • (2013) Int J Gynecol Cancer , vol.23 , Issue.7 , pp. 1326-1330
    • Chereau, E.1    Lambaudie, E.2    Houvenaeghel, G.3
  • 91
    • 84874007884 scopus 로고    scopus 로고
    • Human embryonic stem cells-A potential vaccine for ovarian cancer. Asian pacific journal of cancer prevention
    • Zhang ZJ, Chen XH, Chang XH, et al. Human embryonic stem cells-a potential vaccine for ovarian cancer. Asian Pacific journal of cancer prevention. Asian Pac J Cancer Prev 2012;13(9):4295-4300
    • (2012) Asian Pac J Cancer Prev , vol.13 , Issue.9 , pp. 4295-4300
    • Zhang, Z.J.1    Chen, X.H.2    Chang, X.H.3
  • 92
    • 79952296527 scopus 로고    scopus 로고
    • Immunotherapy for ovarian cancer what's next? Journal of clinical oncology
    • Kandalaft LE, Powell DJ, Jr., Singh N, Coukos G. Immunotherapy for ovarian cancer: What's next? Journal of clinical oncology. J Clin Oncol 2011;29(7):925-933
    • (2011) J Clin Oncol , vol.29 , Issue.7 , pp. 925-933
    • Kandalaft, L.E.1    Powell, D.J.2    Singh, N.3    Coukos, G.4
  • 93
    • 84874625308 scopus 로고    scopus 로고
    • Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer
    • Kandalaft LE, Powell DJ, Jr., et al. Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer. Oncoimmunology 2013;2(1):e22664
    • (2013) Oncoimmunology , vol.2 , Issue.1 , pp. e22664
    • Kandalaft, L.E.1    Powell, D.J.2


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