Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway

Journal of Biological Chemistry

Volumn 289, Issue 32, 2014, Pages 22401-22412

  Perry, David M ^a   Newcomb, Benjamin ^d   Adada, Mohamad ^d   Wu, Bill X ^a   Roddy, Patrick ^a   Kitatani, Kazuyuki ^b   Siskind, Leah ^c   Obeid, Lina M ^e,f   Hannun, Yusuf A ^d  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c University of Louisville School of Medicine   (United States)

^d Stony Brook School of Dental Medicine   (United States)

^e STONY BROOK UNIVERSITY   (United States)

^f Northport Veterans Affairs Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

ACID SPHINGOMYELINASE; BIOLOGICAL PROCESS; CANCER CELLS; INTERLEUKIN-6; SPHINGOLIPIDS;

CELLS;

DESIPRAMINE; ENZYME INHIBITOR; IL6 PROTEIN, HUMAN; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; SMALL INTERFERING RNA; SPHINGOMYELIN PHOSPHODIESTERASE;

ANTAGONISTS AND INHIBITORS; CELL CULTURE; GENE SILENCING; GENETICS; HELA CELL LINE; HUMAN; MCF 7 CELL LINE; METABOLISM; NIEMANN PICK DISEASE; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION;

CELL LINE, TUMOR; CELLS, CULTURED; DESIPRAMINE; ENZYME INHIBITORS; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; INTERLEUKIN-6; MCF-7 CELLS; NEOPLASM INVASIVENESS; NIEMANN-PICK DISEASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHINGOMYELIN PHOSPHODIESTERASE; TETRADECANOYLPHORBOL ACETATE;

EID: 84905852274     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.589648     Document Type: Article

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