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Volumn 35, Issue 2, 2011, Pages 295-304

Sessile serrated adenoma with early neoplastic progression: A clinicopathologic and molecular study

Author keywords

adenocarcinoma; BRAF; KRAS; PIK3CA; serratedneoplasia pathway; sessile serrated adenoma

Indexed keywords

B RAF KINASE; BETA CATENIN; BRAF PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN;

EID: 79251566171     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e318205df36     Document Type: Article
Times cited : (89)

References (40)
  • 1
    • 44449124376 scopus 로고    scopus 로고
    • Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population
    • Abubaker J, Bavi P, Al-Harbi S, et al. Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population. Oncogene. 2008;27:3539-3545.
    • (2008) Oncogene , vol.27 , pp. 3539-3545
    • Abubaker, J.1    Bavi, P.2    Al-Harbi, S.3
  • 2
    • 33847105603 scopus 로고    scopus 로고
    • Microsatellite-unstable mucinous colorectal carcinoma occurring in the elderly: Comparison with medullary type poorly differentiated adenocarcinoma
    • Arai T, Kasahara I, Sawabe M, et al. Microsatellite-unstable mucinous colorectal carcinoma occurring in the elderly: comparison with medullary type poorly differentiated adenocarcinoma. Pathol Int. 2007;57:205-212.
    • (2007) Pathol Int , vol.57 , pp. 205-212
    • Arai, T.1    Kasahara, I.2    Sawabe, M.3
  • 3
    • 42149083899 scopus 로고    scopus 로고
    • Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers
    • Barault L, Veyrie N, Jooste V, et al. Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers. Int J Cancer. 2008;122:2255-2259.
    • (2008) Int J Cancer , vol.122 , pp. 2255-2259
    • Barault, L.1    Veyrie, N.2    Jooste, V.3
  • 4
    • 23244447893 scopus 로고    scopus 로고
    • Tumour biology: Senescence in premalignant tumours
    • Collado M, Gil J, Efeyan A, et al. Tumour biology: senescence in premalignant tumours. Nature. 2005;436:642.
    • (2005) Nature , vol.436 , pp. 642
    • Collado, M.1    Gil, J.2    Efeyan, A.3
  • 5
    • 10044243594 scopus 로고    scopus 로고
    • P53 alterations in colon tumors: A comparison of SSCP/sequencing and immunohistochem-istry
    • Curtin K, Slattery ML, Holubkov R, et al. p53 alterations in colon tumors: a comparison of SSCP/sequencing and immunohistochem-istry. Appl Immunohistochem Mol Morphol. 2004;12:380-386.
    • (2004) Appl Immunohistochem Mol Morphol , vol.12 , pp. 380-386
    • Curtin, K.1    Slattery, M.L.2    Holubkov, R.3
  • 6
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature. 2002;417:949-954.
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 7
    • 9144271690 scopus 로고    scopus 로고
    • Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation
    • Domingo E, Espin E, Armengol M, et al. Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation. Genes Chromosomes Cancer. 2004;39:138-142.
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 138-142
    • Domingo, E.1    Espin, E.2    Armengol, M.3
  • 8
    • 77958011924 scopus 로고    scopus 로고
    • Mucin core protein expression in serrated polyps of the large intestine
    • Fujita K, Hirahashi M, Yamamoto H, et al. Mucin core protein expression in serrated polyps of the large intestine. Virchows Arch. 2010;457:443-449.
    • (2010) Virchows Arch , vol.457 , pp. 443-449
    • Fujita, K.1    Hirahashi, M.2    Yamamoto, H.3
  • 9
    • 30644477199 scopus 로고    scopus 로고
    • Small colonic microsatellite unstable adenocarcino-mas and high-grade epithelial dysplasias in sessile serrated adenoma polypectomy specimens: A study of eight cases
    • Goldstein NS. Small colonic microsatellite unstable adenocarcino-mas and high-grade epithelial dysplasias in sessile serrated adenoma polypectomy specimens: a study of eight cases. Am J Clin Pathol. 2006;125:132-145.
    • (2006) Am J Clin Pathol , vol.125 , pp. 132-145
    • Goldstein, N.S.1
  • 10
    • 85047688083 scopus 로고    scopus 로고
    • Hyperplastic-like colon polyps that preceded microsatellite-unstable adenocarcinomas
    • Goldstein NS, Bhanot P, Odish E, et al. Hyperplastic-like colon polyps that preceded microsatellite-unstable adenocarcinomas. Am J Clin Pathol. 2003;119:778-796.
    • (2003) Am J Clin Pathol , vol.119 , pp. 778-796
    • Goldstein, N.S.1    Bhanot, P.2    Odish, E.3
  • 11
    • 33747192833 scopus 로고    scopus 로고
    • Cellular senescence in naevi and immortalisation in melanoma: A role for p16?
    • Gray-Schopfer VC, Cheong SC, Chong H, et al. Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer. 2006;95:496-505.
    • (2006) Br J Cancer , vol.95 , pp. 496-505
    • Gray-Schopfer, V.C.1    Cheong, S.C.2    Chong, H.3
  • 12
    • 22144467708 scopus 로고    scopus 로고
    • Demographic and pathological characteristics of serrated polyps of colorectum
    • Higuchi T, Sugihara K, Jass JR. Demographic and pathological characteristics of serrated polyps of colorectum. Histopathology. 2005;47:32-40.
    • (2005) Histopathology , vol.47 , pp. 32-40
    • Higuchi, T.1    Sugihara, K.2    Jass, J.R.3
  • 13
    • 0000441155 scopus 로고    scopus 로고
    • DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: A mild mutator pathway for colorectal cancer?
    • Iino H, Jass JR, Simms LA, et al. DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer? J Clin Pathol. 1999;52:5-9.
    • (1999) J Clin Pathol , vol.52 , pp. 5-9
    • Iino, H.1    Jass, J.R.2    Simms, L.A.3
  • 14
    • 33746092527 scopus 로고    scopus 로고
    • Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: Concept of a "fusion" pathway to colorectal cancer
    • Jass JR, Baker K, Zlobec I, et al. Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a "fusion" pathway to colorectal cancer. Histopathology. 2006;49:121-131.
    • (2006) Histopathology , vol.49 , pp. 121-131
    • Jass, J.R.1    Baker, K.2    Zlobec, I.3
  • 15
    • 67349271699 scopus 로고    scopus 로고
    • Paneth cell differentiation in colonic epithelial neoplasms: Evidence for the role of the Apc/beta-catenin/Tcf pathway
    • Joo M, Shahsafaei A, Odze RD. Paneth cell differentiation in colonic epithelial neoplasms: evidence for the role of the Apc/beta-catenin/Tcf pathway. Hum Pathol. 2009;40:872-880.
    • (2009) Hum Pathol , vol.40 , pp. 872-880
    • Joo, M.1    Shahsafaei, A.2    Odze, R.D.3
  • 16
    • 3242686837 scopus 로고    scopus 로고
    • BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
    • Kambara T, Simms LA, Whitehall VL, et al. BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum. Gut. 2004;53:1137-1144.
    • (2004) Gut , vol.53 , pp. 1137-1144
    • Kambara, T.1    Simms, L.A.2    Whitehall, V.L.3
  • 17
    • 77951840779 scopus 로고    scopus 로고
    • KRAS mutations in traditional serrated adenomas from Korea herald an aggressive phenotype
    • Kim KM, Lee EJ, Kim YH, et al. KRAS mutations in traditional serrated adenomas from Korea herald an aggressive phenotype. Am J Surg Pathol. 2010;34:667-675.
    • (2010) Am J Surg Pathol , vol.34 , pp. 667-675
    • Kim, K.M.1    Lee, E.J.2    Kim, Y.H.3
  • 18
    • 57349089198 scopus 로고    scopus 로고
    • Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps
    • Kim YH, Kakar S, Cun L, et al. Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps. Int J Cancer. 2008;123:2587-2593.
    • (2008) Int J Cancer , vol.123 , pp. 2587-2593
    • Kim, Y.H.1    Kakar, S.2    Cun, L.3
  • 19
    • 77954214991 scopus 로고    scopus 로고
    • Longitudinal outcome study of sessile serrated adenomas of the colorectum: An increased risk for subsequent right-sided colorectal carcinoma
    • Lu FI, van Niekerk de W, Owen D, et al. Longitudinal outcome study of sessile serrated adenomas of the colorectum: an increased risk for subsequent right-sided colorectal carcinoma. Am J Surg Pathol. 2010;34:927-934.
    • (2010) Am J Surg Pathol , vol.34 , pp. 927-934
    • Lu, F.I.1    Van Niekerk De, W.2    Owen, D.3
  • 20
    • 33845605907 scopus 로고    scopus 로고
    • Colorectal serrated adenocarcinoma
    • Makinen MJ. Colorectal serrated adenocarcinoma. Histopathology. 2007;50:131-150.
    • (2007) Histopathology , vol.50 , pp. 131-150
    • Makinen, M.J.1
  • 21
    • 33748063941 scopus 로고    scopus 로고
    • Roles of the RAF/ MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
    • McCubrey JA, Steelman LS, Abrams SL, et al. Roles of the RAF/ MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul. 2006;46:249-279.
    • (2006) Adv Enzyme Regul , vol.46 , pp. 249-279
    • McCubrey, J.A.1    Steelman, L.S.2    Abrams, S.L.3
  • 22
    • 23244447037 scopus 로고    scopus 로고
    • BRAFE600-associated senescence-like cell cycle arrest of human naevi
    • Michaloglou C, Vredeveld LC, Soengas MS, et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature. 2005;436:720-724.
    • (2005) Nature , vol.436 , pp. 720-724
    • Michaloglou, C.1    Vredeveld, L.C.2    Soengas, M.S.3
  • 23
    • 33749063204 scopus 로고    scopus 로고
    • Senescence and serration: A new twist to an old tale
    • Minoo P, Jass JR. Senescence and serration: a new twist to an old tale. J Pathol. 2006;210:137-140.
    • (2006) J Pathol , vol.210 , pp. 137-140
    • Minoo, P.1    Jass, J.R.2
  • 24
    • 34548280882 scopus 로고    scopus 로고
    • Mutations of the PIK3CA gene in hereditary colorectal cancers
    • Miyaki M, Iijima T, Yamaguchi T, et al. Mutations of the PIK3CA gene in hereditary colorectal cancers. Int J Cancer. 2007;121: 1627-1630.
    • (2007) Int J Cancer , vol.121 , pp. 1627-1630
    • Miyaki, M.1    Iijima, T.2    Yamaguchi, T.3
  • 25
    • 33751320353 scopus 로고    scopus 로고
    • Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points
    • O'Brien MJ, Yang S, Mack C, et al. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol. 2006;30:1491-1501.
    • (2006) Am J Surg Pathol , vol.30 , pp. 1491-1501
    • O'Brien, M.J.1    Yang, S.2    MacK, C.3
  • 26
    • 63049111794 scopus 로고    scopus 로고
    • PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer
    • Ogino S, Nosho K, Kirkner GJ, et al. PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer. J Clin Oncol. 2009;27:1477-1484.
    • (2009) J Clin Oncol , vol.27 , pp. 1477-1484
    • Ogino, S.1    Nosho, K.2    Kirkner, G.J.3
  • 27
    • 13444270782 scopus 로고    scopus 로고
    • Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon
    • Oh K, Redston M, Odze RD. Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon. Hum Pathol. 2005;36:101-111.
    • (2005) Hum Pathol , vol.36 , pp. 101-111
    • Oh, K.1    Redston, M.2    Odze, R.D.3
  • 28
    • 0346057796 scopus 로고    scopus 로고
    • BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency
    • Oliveira C, Pinto M, Duval A, et al. BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency. Oncogene. 2003;22:9192-9196.
    • (2003) Oncogene , vol.22 , pp. 9192-9196
    • Oliveira, C.1    Pinto, M.2    Duval, A.3
  • 29
    • 34147145962 scopus 로고    scopus 로고
    • Survivin and hedgehog protein expression in serrated colorectal polyps: An immunohistochemical study
    • Parfitt JR, Driman DK. Survivin and hedgehog protein expression in serrated colorectal polyps: an immunohistochemical study. Hum Pathol. 2007;38:710-717.
    • (2007) Hum Pathol , vol.38 , pp. 710-717
    • Parfitt, J.R.1    Driman, D.K.2
  • 30
    • 33745591883 scopus 로고    scopus 로고
    • Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location
    • Park SY, Lee HS, Choe G, et al. Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location. Virchows Arch. 2006;449:40-47.
    • (2006) Virchows Arch , vol.449 , pp. 40-47
    • Park, S.Y.1    Lee, H.S.2    Choe, G.3
  • 31
    • 11144358645 scopus 로고    scopus 로고
    • High frequency of mutations of the PIK3CA gene in human cancers
    • Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science. 2004;304:554.
    • (2004) Science , vol.304 , pp. 554
    • Samuels, Y.1    Wang, Z.2    Bardelli, A.3
  • 32
    • 0033944069 scopus 로고    scopus 로고
    • The Vienna classification of gastrointestinal epithelial neoplasia
    • Schlemper RJ, Riddell RH, Kato Y, et al. The Vienna classification of gastrointestinal epithelial neoplasia. Gut. 2000;47:251-255.
    • (2000) Gut , vol.47 , pp. 251-255
    • Schlemper, R.J.1    Riddell, R.H.2    Kato, Y.3
  • 33
    • 33749344617 scopus 로고    scopus 로고
    • Sessile serrated adenomas with low- and high-grade dysplasia and early carcinomas: An immunohistochemical study of serrated lesions "caught in the act"
    • Sheridan TB, Fenton H, Lewin MR, et al. Sessile serrated adenomas with low- and high-grade dysplasia and early carcinomas: an immunohistochemical study of serrated lesions "caught in the act". Am J Clin Pathol. 2006;126:564-571.
    • (2006) Am J Clin Pathol , vol.126 , pp. 564-571
    • Sheridan, T.B.1    Fenton, H.2    Lewin, M.R.3
  • 34
    • 24144491263 scopus 로고    scopus 로고
    • Serrated polyps of the large intestine: A morphologic and molecular review of an evolving concept
    • Snover DC, Jass JR, Fenoglio-Preiser C, et al. Serrated polyps of the large intestine: a morphologic and molecular review of an evolving concept. Am J Clin Pathol. 2005;124:380-391.
    • (2005) Am J Clin Pathol , vol.124 , pp. 380-391
    • Snover, D.C.1    Jass, J.R.2    Fenoglio-Preiser, C.3
  • 35
    • 33750682008 scopus 로고    scopus 로고
    • High prevalence of sessile serrated adenomas with BRAF mutations: A prospective study of patients undergoing colonoscopy
    • Spring KJ, Zhao ZZ, Karamatic R, et al. High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology. 2006;131: 1400-1407.
    • (2006) Gastroenterology , vol.131 , pp. 1400-1407
    • Spring, K.J.1    Zhao, Z.Z.2    Karamatic, R.3
  • 36
    • 0037216302 scopus 로고    scopus 로고
    • Morphologic reappraisal of serrated colorectal polyps
    • Torlakovic E, Skovlund E, Snover DC, et al. Morphologic reappraisal of serrated colorectal polyps. Am J Surg Pathol. 2003; 27:65-81.
    • (2003) Am J Surg Pathol , vol.27 , pp. 65-81
    • Torlakovic, E.1    Skovlund, E.2    Snover, D.C.3
  • 37
    • 68649084906 scopus 로고    scopus 로고
    • Pathologic features and biologic importance of colorectal serrated polyps
    • Vakiani E, Yantiss RK. Pathologic features and biologic importance of colorectal serrated polyps. Adv Anat Pathol. 2009;16:79-91.
    • (2009) Adv Anat Pathol , vol.16 , pp. 79-91
    • Vakiani, E.1    Yantiss, R.K.2
  • 38
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med. 1988;319:525-532.
    • (1988) N Engl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 39
    • 73349134675 scopus 로고    scopus 로고
    • Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation
    • Yachida S, Mudali S, Martin SA, et al. Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation. Am J Surg Pathol. 2009;33:1823-1832.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1823-1832
    • Yachida, S.1    Mudali, S.2    Martin, S.A.3
  • 40
    • 7044253667 scopus 로고    scopus 로고
    • BRAF and KRAS mutations in hyperplastic polyps and serrated adenomas of the colorectum: Relationship to histology and CpG island methylation status
    • Yang S, Farraye FA, Mack C, et al. BRAF and KRAS mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004;28:1452-1459.
    • (2004) Am J Surg Pathol , vol.28 , pp. 1452-1459
    • Yang, S.1    Farraye, F.A.2    MacK, C.3


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