Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation

American Journal of Surgical Pathology

Volumn 33, Issue 12, 2009, Pages 1823-1832

  Yachida, Shinichi ^a   Mudali, Shiyama ^a   Martin, Sherri A ^a,b   Montgomery, Elizabeth A ^a   Iacobuzio Donahue, Christine A ^a,c  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Beta catenin; Colon cancer; Hyperplastic polyp; Serrated adenoma; Wnt pathway

Indexed keywords

B RAF KINASE; BETA CATENIN; BRAF PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

ADENOMA; AGED; ARTICLE; CELL NUCLEUS; CELL TRANSFORMATION; CHEMISTRY; COLON POLYP; COLORECTAL TUMOR; FEMALE; GENETICS; HUMAN; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; TRANSCRIPTION INITIATION;

ADENOMA; AGED; BASE SEQUENCE; BETA CATENIN; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; COLONIC POLYPS; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; TRANSCRIPTIONAL ACTIVATION;

EID: 73349134675     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e3181b6da19     Document Type: Article

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