The KDM5 family of histone demethylases as targets in oncology drug discovery

Epigenomics

Volumn 6, Issue 3, 2014, Pages 277-286

  Rasmussen, Peter Birk ^a,b   Staller, Peter ^a  

^a EpiTherapeutics   (Denmark)

^b Accelerace Management   (Denmark)

Author keywords

cancer; enzymatic inhibitors; epigenetics; gene transcription; H3K4 methylation; histone demethylase; jumonji; oncogenes

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; HISTONE; HISTONE DEMETHYLASE; KDM5A PROTEIN, HUMAN; KDM5B PROTEIN, HUMAN; NUCLEAR PROTEIN; REPRESSOR PROTEIN; RETINOBLASTOMA BINDING PROTEIN 2;

ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG DESIGN; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; NEOPLASM; PATHOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DESIGN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; NEOPLASMS; NUCLEAR PROTEINS; REPRESSOR PROTEINS; RETINOBLASTOMA-BINDING PROTEIN 2;

EID: 84905815231     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.14.14     Document Type: Article

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