TLR4 activation induces IL-1β release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung

Respiratory Research

Volumn 15, Issue 1, 2014, Pages

  Eltom, Suffwan ^a   Belvisi, Maria G ^a   Yew Booth, Liang ^a   Dekkak, Bilel ^a   Maher, Sarah A ^a   Dubuis, Eric D ^a   Jones, Victoria ^a   Fitzgerald, Kate A ^b   Birrell, Mark A ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

ASC; IL 1 release; IPAF; TLR4

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CARD; CASPASE 11; CASPASE 8; ENZYME ACTIVATOR; ICE PROTEASE ACTIVATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; LUNG ENZYME; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; AEROSOL; APOPTOSIS REGULATORY PROTEIN; AUTACOID; CALCIUM BINDING PROTEIN; CASP11 PROTEIN, MOUSE; CASP8 PROTEIN, MOUSE; CASPASE; ENDOTOXIN; ENDOTOXIN, ESCHERICHIA COLI; IL1B PROTEIN, MOUSE; IPAF PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENZYME ACTIVITY; INNATE IMMUNITY; LUNG; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; IMMUNOLOGY; INHALATIONAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; MALE; METABOLISM; TIME FACTOR;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; APOPTOSIS REGULATORY PROTEINS; BRONCHOALVEOLAR LAVAGE FLUID; CALCIUM-BINDING PROTEINS; CASPASE 1; CASPASE 8; CASPASES; ENDOTOXINS; INFLAMMATION MEDIATORS; INTERLEUKIN-18; INTERLEUKIN-1BETA; LUNG; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 84905757030     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-014-0087-0     Document Type: Article

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