Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity

Molecular Metabolism

Volumn 2, Issue 2, 2013, Pages 74-85

  Schneeberger, Marc ^a,b,c   Altirriba, Jordi ^d   García, Ainhoa ^a,b   Esteban, Yaiza ^a,b   Castaño, Carlos ^a,b   García Lavandeira, Montserrat ^e   Alvarez, Clara V ^e   Gomis, Ramon ^a,b,c   Claret, Marc ^a,b  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Dicer; Hypothalamus; MicroRNA; Neurodegeneration; Obesity; POMC

Indexed keywords

DICER; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; PROOPIOMELANOCORTIN; PROTEASOME; RIBONUCLEASE; UBIQUITIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; DOWN REGULATION; FEMALE; HYPERLEPTINEMIA; HYPERPHAGIA; HYPOPHYSIS ADRENAL SYSTEM; HYPOPHYSIS DISEASE; HYPOTHALAMUS; MALE; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; NUTRIENT AVAILABILITY; OBESITY; PHENOTYPE; PRIORITY JOURNAL; RIBOSOME; RNA PROCESSING; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS;

EID: 84877659963     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2012.10.001     Document Type: Article

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