-
1
-
-
0034705319
-
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53
-
doi: 10.1016/S0092-8674(00)80887-9
-
Buschmann, T., Fuchs, S. Y., Lee, C. G., Pan, Z. Q., and Ronai, Z. (2000). SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53. Cell 101, 753-762. doi: 10.1016/S0092-8674(00)80887-9
-
(2000)
Cell
, vol.101
, pp. 753-762
-
-
Buschmann, T.1
Fuchs, S.Y.2
Lee, C.G.3
Pan, Z.Q.4
Ronai, Z.5
-
2
-
-
34248566788
-
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
-
doi: 10.1126/science.1141194
-
Busino, L., Bassermann, F., Maiolica, A., Lee, C., Nolan, P. M., Godinho, S. I., et al. (2007). SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science 316, 900-904. doi: 10.1126/science.1141194
-
(2007)
Science
, vol.316
, pp. 900-904
-
-
Busino, L.1
Bassermann, F.2
Maiolica, A.3
Lee, C.4
Nolan, P.M.5
Godinho, S.I.6
-
3
-
-
23944470712
-
Circadian clock control by SUMOylation of BMAL1
-
doi: 10.1126/science.1110689
-
Cardone, L., Hirayama, J., Giordano, F., Tamaru, T., Palvimo, J. J., and Sassone-Corsi, P. (2005). Circadian clock control by SUMOylation of BMAL1. Science 309, 1390-1394. doi: 10.1126/science.1110689
-
(2005)
Science
, vol.309
, pp. 1390-1394
-
-
Cardone, L.1
Hirayama, J.2
Giordano, F.3
Tamaru, T.4
Palvimo, J.J.5
Sassone-Corsi, P.6
-
4
-
-
4444318673
-
The SCF ubiquitin ligase: Insights into a molecular machine
-
doi: 10.1038/nrm1471
-
Cardozo, T., and Pagano, M. (2004). The SCF ubiquitin ligase: insights into a molecular machine. Nat. Rev. Mol. Cell Biol. 5, 739-751. doi: 10.1038/nrm1471
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 739-751
-
-
Cardozo, T.1
Pagano, M.2
-
5
-
-
79955540602
-
NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed
-
doi: 10.1016/j.cell.2011.04.002
-
Chiu, J. C., Ko, H. W., and Edery, I. (2011). NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speed. Cell 145, 357-370. doi: 10.1016/j.cell.2011.04.002
-
(2011)
Cell
, vol.145
, pp. 357-370
-
-
Chiu, J.C.1
Ko, H.W.2
Edery, I.3
-
6
-
-
46249098507
-
The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock
-
doi: 10.1101/gad.1682708
-
Chiu, J. C., Vanselow, J. T., Kramer, A., and Edery, I. (2008). The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock. Genes Dev. 22, 1758-1772. doi: 10.1101/gad.1682708
-
(2008)
Genes Dev.
, vol.22
, pp. 1758-1772
-
-
Chiu, J.C.1
Vanselow, J.T.2
Kramer, A.3
Edery, I.4
-
7
-
-
84878889999
-
Structures ofDrosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function
-
doi: 10.1016/j.cell.2013.05.011
-
Czarna, A., Berndt, A., Singh, H. R., Grudziecki, A., Ladurner, A. G., Timinszky, G., et al. (2013). Structures ofDrosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell 153, 1394-1405. doi: 10.1016/j.cell.2013.05.011
-
(2013)
Cell
, vol.153
, pp. 1394-1405
-
-
Czarna, A.1
Berndt, A.2
Singh, H.R.3
Grudziecki, A.4
Ladurner, A.G.5
Timinszky, G.6
-
8
-
-
33947193633
-
Cryptochromes impair phosphorylation of transcriptional activators in the clock: A general mechanism for circadian repression
-
doi: 10.1042/BJ20060827
-
Dardente, H., Fortier, E. E., Martineau, V., and Cermakian, N. (2007). Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression. Biochem. J. 402, 525-536. doi: 10.1042/BJ20060827
-
(2007)
Biochem. J.
, vol.402
, pp. 525-536
-
-
Dardente, H.1
Fortier, E.E.2
Martineau, V.3
Cermakian, N.4
-
9
-
-
55849113304
-
Implication of the F-Box Protein FBXL21 in circadian pacemaker function in mammals
-
doi: 10.1371/journal.pone.0003530
-
Dardente, H., Mendoza, J., Fustin, J. M., Challet, E., and Hazlerigg, D. G. (2008). Implication of the F-Box Protein FBXL21 in circadian pacemaker function in mammals. PLoS ONE 3:e3530. doi: 10.1371/journal.pone.0003530
-
(2008)
PLoS ONE
, vol.3
-
-
Dardente, H.1
Mendoza, J.2
Fustin, J.M.3
Challet, E.4
Hazlerigg, D.G.5
-
10
-
-
0032135131
-
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation
-
doi: 10.1016/S1097-2765(00)80133-1
-
Desterro, J. M., Rodriguez, M. S., and Hay, R. T. (1998). SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol. Cell 2, 233-239. doi: 10.1016/S1097-2765(00)80133-1
-
(1998)
Mol. Cell
, vol.2
, pp. 233-239
-
-
Desterro, J.M.1
Rodriguez, M.S.2
Hay, R.T.3
-
11
-
-
77951889295
-
The mammalian circadian timing system: Organization and coordination of central and peripheral clocks
-
doi: 10.1146/annurev-physiol-021909-135821
-
Dibner, C., Schibler, U., and Albrecht, U. (2010). The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu. Rev. Physiol. 72, 517-549. doi: 10.1146/annurev-physiol-021909-135821
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 517-549
-
-
Dibner, C.1
Schibler, U.2
Albrecht, U.3
-
12
-
-
73649092106
-
The crosstalk between physiology and circadian clock proteins
-
doi: 10.3109/07420520903497575
-
Duguay, D., and Cermakian, N. (2009). The crosstalk between physiology and circadian clock proteins. Chronobiol. Int. 26, 1479-1513. doi: 10.3109/07420520903497575
-
(2009)
Chronobiol. Int.
, vol.26
, pp. 1479-1513
-
-
Duguay, D.1
Cermakian, N.2
-
13
-
-
15044343742
-
Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation
-
doi: 10.1128/MCB.25.7.2795-2807.2005
-
Eide, E. J., Woolf, M. F., Kang, H., Woolf, P., Hurst, W., Camacho, F., et al. (2005). Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation. Mol. Cell. Biol. 25, 2795-2807. doi: 10.1128/MCB.25.7.2795-2807.2005
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2795-2807
-
-
Eide, E.J.1
Woolf, M.F.2
Kang, H.3
Woolf, P.4
Hurst, W.5
Camacho, F.6
-
14
-
-
84896723156
-
Health consequences of circadian disruption in humans and animal models
-
doi: 10.1016/B978-0-12-396971-2.00010-5
-
Evans, J. A., and Davidson, A. J. (2013). Health consequences of circadian disruption in humans and animal models. Prog. Mol. Biol. Transl. Sci. 119, 283-323. doi: 10.1016/B978-0-12-396971-2.00010-5
-
(2013)
Prog. Mol. Biol. Transl. Sci.
, vol.119
, pp. 283-323
-
-
Evans, J.A.1
Davidson, A.J.2
-
15
-
-
33847779219
-
Post-translational modifications regulate the ticking of the circadian clock
-
doi: 10.1038/nrm2106
-
Gallego, M., and Virshup, D. M. (2007). Post-translational modifications regulate the ticking of the circadian clock. Nat. Rev. Mol. Cell Biol. 8, 139-148. doi: 10.1038/nrm2106
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 139-148
-
-
Gallego, M.1
Virshup, D.M.2
-
16
-
-
34248525919
-
The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period
-
doi: 10.1126/science. 1141138
-
Godinho, S. I., Maywood, E. S., Shaw, L., Tucci, V., Barnard, A. R., Busino, L., et al. (2007). The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science 316, 897-900. doi: 10.1126/science. 1141138
-
(2007)
Science
, vol.316
, pp. 897-900
-
-
Godinho, S.I.1
Maywood, E.S.2
Shaw, L.3
Tucci, V.4
Barnard, A.R.5
Busino, L.6
-
17
-
-
84901335708
-
The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor
-
doi: 10.1093/nar/gku225
-
Gossan, N. C., Zhang, F., Guo, B., Jin, D., Yoshitane, H., Yao, A., et al. (2014). The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor. Nucleic Acids Res. 42, 5765-5775. doi: 10.1093/nar/gku225
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 5765-5775
-
-
Gossan, N.C.1
Zhang, F.2
Guo, B.3
Jin, D.4
Yoshitane, H.5
Yao, A.6
-
18
-
-
0037079034
-
The F-box protein slimb controls the levels of clock proteins period and timeless
-
doi: 10.1038/nature01122
-
Grima, B., Lamouroux, A., Chelot, E., Papin, C., Limbourg-Bouchon, B., and Rouyer, F. (2002). The F-box protein slimb controls the levels of clock proteins period and timeless. Nature 420, 178-182. doi: 10.1038/nature01122
-
(2002)
Nature
, vol.420
, pp. 178-182
-
-
Grima, B.1
Lamouroux, A.2
Chelot, E.3
Papin, C.4
Limbourg-Bouchon, B.5
Rouyer, F.6
-
19
-
-
84896520139
-
Ubiquitin code assembly and disassembly
-
doi: 10.1016/j.cub.2014.02.002
-
Heride, C., Urbe, S., and Clague, M. J. (2014). Ubiquitin code assembly and disassembly. Curr. Biol. 24, R215-R220. doi: 10.1016/j.cub.2014.02.002
-
(2014)
Curr. Biol.
, vol.24
-
-
Heride, C.1
Urbe, S.2
Clague, M.J.3
-
20
-
-
84874772651
-
FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes
-
doi: 10.1016/j.cell.2013.01.054
-
Hirano, A., Yumimoto, K., Tsunematsu, R., Matsumoto, M., Oyama, M., Kozuka-Hata, H., et al. (2013). FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes. Cell 152, 1106-1118. doi: 10.1016/j.cell.2013.01.054
-
(2013)
Cell
, vol.152
, pp. 1106-1118
-
-
Hirano, A.1
Yumimoto, K.2
Tsunematsu, R.3
Matsumoto, M.4
Oyama, M.5
Kozuka-Hata, H.6
-
21
-
-
37249053976
-
CLOCK-mediated acetylation of BMAL1 controls circadian function
-
doi: 10.1038/nature06394
-
Hirayama, J., Sahar, S., Grimaldi, B., Tamaru, T., Takamatsu, K., Nakahata, Y., et al. (2007). CLOCK-mediated acetylation of BMAL1 controls circadian function. Nature 450, 1086-1090. doi: 10.1038/nature06394
-
(2007)
Nature
, vol.450
, pp. 1086-1090
-
-
Hirayama, J.1
Sahar, S.2
Grimaldi, B.3
Tamaru, T.4
Takamatsu, K.5
Nakahata, Y.6
-
22
-
-
84865558040
-
Identification of small molecule activators of cryptochrome
-
doi: 10.1126/science.1223710
-
Hirota, T., Lee, J. W., St. John, P. C., Sawa, M., Iwaisako, K., Noguchi, T., et al. (2012). Identification of small molecule activators of cryptochrome. Science 337, 1094-1097. doi: 10.1126/science.1223710
-
(2012)
Science
, vol.337
, pp. 1094-1097
-
-
Hirota, T.1
Lee, J.W.2
St. John, P.C.3
Sawa, M.4
Iwaisako, K.5
Noguchi, T.6
-
23
-
-
0036152706
-
Implications of circadian gene expression in kidney, liver and the effects of fasting on pharmacogenomic studies
-
doi: 10.1097/00008571-200201000-00008
-
Kita, Y., Shiozawa, M., Jin, W., Majewski, R. R., Besharse, J. C., Greene, A. S., et al. (2002). Implications of circadian gene expression in kidney, liver and the effects of fasting on pharmacogenomic studies. Pharmacogenetics 12, 55-65. doi: 10.1097/00008571-200201000-00008
-
(2002)
Pharmacogenetics
, vol.12
, pp. 55-65
-
-
Kita, Y.1
Shiozawa, M.2
Jin, W.3
Majewski, R.R.4
Besharse, J.C.5
Greene, A.S.6
-
24
-
-
0037069671
-
Role for slimb in the degradation of Drosophila period protein phosphorylated by doubletime
-
doi: 10.1038/nature01272
-
Ko, H. W., Jiang, J., and Edery, I. (2002). Role for slimb in the degradation of Drosophila period protein phosphorylated by doubletime. Nature 420, 673-678. doi: 10.1038/nature01272
-
(2002)
Nature
, vol.420
, pp. 673-678
-
-
Ko, H.W.1
Jiang, J.2
Edery, I.3
-
25
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
doi: 10.1038/nrm2731
-
Komander, D., Clague, M. J., and Urbe, S. (2009). Breaking the chains: structure and function of the deubiquitinases. Nat. Rev. Mol. Cell Biol. 10, 550-563. doi: 10.1038/nrm2731
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
26
-
-
0042626226
-
BMAL1-dependent circadian oscillation of nuclear CLOCK: Posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
-
doi: 10.1101/gad.1099503
-
Kondratov, R. V., Chernov, M. V., Kondratova, A. A., Gorbacheva, V. Y., Gudkov, A. V., and Antoch, M. P. (2003). BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system. Genes Dev. 17, 1921-1932. doi: 10.1101/gad.1099503
-
(2003)
Genes Dev.
, vol.17
, pp. 1921-1932
-
-
Kondratov, R.V.1
Chernov, M.V.2
Kondratova, A.A.3
Gorbacheva, V.Y.4
Gudkov, A.V.5
Antoch, M.P.6
-
27
-
-
33746235094
-
Post-translational regulation of circadian transcriptional CLOCK(NPAS2)/BMAL1 complex by CRYPTOCHROMES
-
doi: 10.4161/cc.5.8.2684
-
Kondratov, R. V., Kondratova, A. A., Lee, C., Gorbacheva, V. Y., Chernov, M. V., and Antoch, M. P. (2006). Post-translational regulation of circadian transcriptional CLOCK(NPAS2)/BMAL1 complex by CRYPTOCHROMES. Cell Cycle 5, 890-895. doi: 10.4161/cc.5.8.2684
-
(2006)
Cell Cycle
, vol.5
, pp. 890-895
-
-
Kondratov, R.V.1
Kondratova, A.A.2
Lee, C.3
Gorbacheva, V.Y.4
Chernov, M.V.5
Antoch, M.P.6
-
28
-
-
77949363859
-
DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping
-
doi: 10.1128/MCB.01047-09
-
Kurabayashi, N., Hirota, T., Sakai, M., Sanada, K., and Fukada, Y. (2010). DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping. Mol. Cell. Biol. 30, 1757-1768. doi: 10.1128/MCB.01047-09
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1757-1768
-
-
Kurabayashi, N.1
Hirota, T.2
Sakai, M.3
Sanada, K.4
Fukada, Y.5
-
29
-
-
33749169177
-
BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer
-
doi: 10.1128/MCB.00337-06
-
Kwon, I., Lee, J., Chang, S. H., Jung, N. C., Lee, B. J., Son, G. H., et al. (2006). BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer. Mol. Cell. Biol. 26, 7318-7330. doi: 10.1128/MCB.00337-06
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7318-7330
-
-
Kwon, I.1
Lee, J.2
Chang, S.H.3
Jung, N.C.4
Lee, B.J.5
Son, G.H.6
-
30
-
-
70350128135
-
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
-
doi: 10.1126/science.1172156
-
Lamia, K. A., Sachdeva, U. M., Ditacchio, L., Williams, E. C., Alvarez, J. G., Egan, D. F., et al. (2009). AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science 326, 437-440. doi: 10.1126/science.1172156
-
(2009)
Science
, vol.326
, pp. 437-440
-
-
Lamia, K.A.1
Sachdeva, U.M.2
Ditacchio, L.3
Williams, E.C.4
Alvarez, J.G.5
Egan, D.F.6
-
31
-
-
52649158231
-
Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex
-
doi: 10.1128/MCB.00583-08
-
Lee, J., Lee, Y., Lee, M. J., Park, E., Kang, S. H., Chung, C. H., et al. (2008). Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol. Cell. Biol. 28, 6056-6065. doi: 10.1128/MCB.00583-08
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6056-6065
-
-
Lee, J.1
Lee, Y.2
Lee, M.J.3
Park, E.4
Kang, S.H.5
Chung, C.H.6
-
32
-
-
84873362932
-
O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination
-
doi: 10.1016/j.cmet.2012.12.015
-
Li, M. D., Ruan, H. B., Hughes, M. E., Lee, J. S., Singh, J. P., Jones, S. P., et al. (2013). O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. Cell Metab. 17, 303-310. doi: 10.1016/j.cmet.2012.12.015
-
(2013)
Cell Metab.
, vol.17
, pp. 303-310
-
-
Li, M.D.1
Ruan, H.B.2
Hughes, M.E.3
Lee, J.S.4
Singh, J.P.5
Jones, S.P.6
-
33
-
-
84869191713
-
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
-
doi: 10.1101/gad.200584.112
-
Luo, W., Li, Y., Tang, C. H., Abruzzi, K. C., Rodriguez, J., Pescatore, S., et al. (2012). CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila. Genes Dev. 26, 2536-2549. doi: 10.1101/gad.200584.112
-
(2012)
Genes Dev.
, vol.26
, pp. 2536-2549
-
-
Luo, W.1
Li, Y.2
Tang, C.H.3
Abruzzi, K.C.4
Rodriguez, J.5
Pescatore, S.6
-
34
-
-
84860568860
-
Ubiquitin-specific protease 2 regulates hepatic gluconeogenesis and diurnal glucose metabolism through 11beta-hydroxysteroid dehydrogenase 1
-
doi: 10.2337/db11-0970
-
Molusky, M. M., Li, S., Ma, D., Yu, L., and Lin, J. D. (2012a). Ubiquitin-specific protease 2 regulates hepatic gluconeogenesis and diurnal glucose metabolism through 11beta-hydroxysteroid dehydrogenase 1. Diabetes 61, 1025-1035. doi: 10.2337/db11-0970
-
(2012)
Diabetes
, vol.61
, pp. 1025-1035
-
-
Molusky, M.M.1
Li, S.2
Ma, D.3
Yu, L.4
Lin, J.D.5
-
35
-
-
84868316791
-
Peroxisomal localization and circadian regulation of ubiquitin-specific protease 2
-
doi: 10.1371/journal.pone.0047970
-
Molusky, M. M., Ma, D., Buelow, K., Yin, L., and Lin, J. D. (2012b). Peroxisomal localization and circadian regulation of ubiquitin-specific protease 2. PLoS ONE 7:e47970. doi: 10.1371/journal.pone.0047970
-
(2012)
PLoS ONE
, vol.7
-
-
Molusky, M.M.1
Ma, D.2
Buelow, K.3
Yin, L.4
Lin, J.D.5
-
36
-
-
0035286622
-
SUMO, ubiquitin's mysterious cousin
-
doi: 10.1038/35056591
-
Muller, S., Hoege, C., Pyrowolakis, G., and Jentsch, S. (2001). SUMO, ubiquitin's mysterious cousin. Nat. Rev. Mol. Cell Biol. 2, 202-210. doi: 10.1038/35056591
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 202-210
-
-
Muller, S.1
Hoege, C.2
Pyrowolakis, G.3
Jentsch, S.4
-
37
-
-
55349127867
-
The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2
-
doi: 10.1093/jb/mvn112
-
Ohsaki, K., Oishi, K., Kozono, Y., Nakayama, K., Nakayama, K. I., and Ishida, N. (2008). The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2. J. Biochem. 144, 609-618. doi: 10.1093/jb/mvn112
-
(2008)
J. Biochem.
, vol.144
, pp. 609-618
-
-
Ohsaki, K.1
Oishi, K.2
Kozono, Y.3
Nakayama, K.4
Nakayama, K.I.5
Ishida, N.6
-
38
-
-
16744364055
-
Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes
-
doi: 10.1074/jbc.M304564200
-
Oishi, K., Miyazaki, K., Kadota, K., Kikuno, R., Nagase, T., Atsumi, G., et al. (2003). Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes. J. Biol. Chem. 278, 41519-41527. doi: 10.1074/jbc.M304564200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 41519-41527
-
-
Oishi, K.1
Miyazaki, K.2
Kadota, K.3
Kikuno, R.4
Nagase, T.5
Atsumi, G.6
-
39
-
-
34848913124
-
Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics
-
doi: 10.1177/0748730407303926
-
Reischl, S., Vanselow, K., Westermark, P. O., Thierfelder, N., Maier, B., Herzel, H., et al. (2007). Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics. J. Biol. Rhythms 22, 375-386. doi: 10.1177/0748730407303926
-
(2007)
J. Biol. Rhythms
, vol.22
, pp. 375-386
-
-
Reischl, S.1
Vanselow, K.2
Westermark, P.O.3
Thierfelder, N.4
Maier, B.5
Herzel, H.6
-
40
-
-
33644617485
-
Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions
-
doi: 10.1038/ng1738
-
Ripperger, J. A., and Schibler, U. (2006). Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions. Nat. Genet. 38, 369-374. doi: 10.1038/ng1738
-
(2006)
Nat. Genet.
, vol.38
, pp. 369-374
-
-
Ripperger, J.A.1
Schibler, U.2
-
41
-
-
77649144065
-
Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation
-
doi: 10.1371/journal.pone.0008561
-
Sahar, S., Zocchi, L., Kinoshita, C., Borrelli, E., and Sassone-Corsi, P. (2010). Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. PLoS ONE 5:e8561. doi: 10.1371/journal.pone.0008561
-
(2010)
PLoS ONE
, vol.5
-
-
Sahar, S.1
Zocchi, L.2
Kinoshita, C.3
Borrelli, E.4
Sassone-Corsi, P.5
-
42
-
-
80053107902
-
The de-ubiquitinylating enzyme, USP2, is associated with the circadian clockwork and regulates its sensitivity to light
-
doi: 10.1371/journal.pone.0025382
-
Scoma, H. D., Humby, M., Yadav, G., Zhang, Q., Fogerty, J., and Besharse, J. C. (2011). The de-ubiquitinylating enzyme, USP2, is associated with the circadian clockwork and regulates its sensitivity to light. PLoS ONE 6:e25382. doi: 10.1371/journal.pone.0025382
-
(2011)
PLoS ONE
, vol.6
-
-
Scoma, H.D.1
Humby, M.2
Yadav, G.3
Zhang, Q.4
Fogerty, J.5
Besharse, J.C.6
-
43
-
-
84875279589
-
Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock
-
doi: 10.1073/pnas.1302560110
-
Shi, G., Xing, L., Liu, Z., Qu, Z., Wu, X., Dong, Z., et al. (2013). Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock. Proc. Natl. Acad. Sci. U.S.A.110, 4750-4755. doi: 10.1073/pnas.1302560110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 4750-4755
-
-
Shi, G.1
Xing, L.2
Liu, Z.3
Qu, Z.4
Wu, X.5
Dong, Z.6
-
44
-
-
22844432019
-
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein
-
doi: 10.1074/jbc.M502862200
-
Shirogane, T., Jin, J., Ang, X. L., and Harper, J. W. (2005). SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J. Biol. Chem. 280, 26863-26872. doi: 10.1074/jbc.M502862200
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26863-26872
-
-
Shirogane, T.1
Jin, J.2
Ang, X.L.3
Harper, J.W.4
-
45
-
-
34249097203
-
Circadian mutant overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression
-
doi: 10.1016/j.cell.2007.04.030
-
Siepka, S. M., Yoo, S. H., Park, J., Song, W., Kumar, V., Hu, Y., et al. (2007). Circadian mutant overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell 129, 1011-1023. doi: 10.1016/j.cell.2007.04.030
-
(2007)
Cell
, vol.129
, pp. 1011-1023
-
-
Siepka, S.M.1
Yoo, S.H.2
Park, J.3
Song, W.4
Kumar, V.5
Hu, Y.6
-
46
-
-
0037007625
-
Extensive and divergent circadian gene expression in liver and heart
-
doi: 10.1038/nature744
-
Storch, K. F., Lipan, O., Leykin, I., Viswanathan, N., Davis, F. C., Wong, W. H., et al. (2002). Extensive and divergent circadian gene expression in liver and heart. Nature 417, 78-83. doi: 10.1038/nature744
-
(2002)
Nature
, vol.417
, pp. 78-83
-
-
Storch, K.F.1
Lipan, O.2
Leykin, I.3
Viswanathan, N.4
Davis, F.C.5
Wong, W.H.6
-
47
-
-
84868097990
-
Circadian Dbp transcription relies on highly dynamic BMAL1-CLOCK interaction with E boxes and requires the proteasome
-
doi: 10.1016/j.molcel.2012.08.012
-
Stratmann, M., Suter, D. M., Molina, N., Naef, F., and Schibler, U. (2012). Circadian Dbp transcription relies on highly dynamic BMAL1-CLOCK interaction with E boxes and requires the proteasome. Mol. Cell 48, 277-287. doi: 10.1016/j.molcel.2012.08.012
-
(2012)
Mol. Cell
, vol.48
, pp. 277-287
-
-
Stratmann, M.1
Suter, D.M.2
Molina, N.3
Naef, F.4
Schibler, U.5
-
48
-
-
84864089093
-
USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signals
-
doi: 10.1074/jbc.M112.340786
-
Tong, X., Buelow, K., Guha, A., Rausch, R., and Yin, L. (2012). USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signals. J. Biol. Chem. 287, 25280-25291. doi: 10.1074/jbc.M112.340786
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 25280-25291
-
-
Tong, X.1
Buelow, K.2
Guha, A.3
Rausch, R.4
Yin, L.5
-
49
-
-
84875899177
-
SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket
-
doi: 10.1038/nature11964
-
Xing, W., Busino, L., Hinds, T. R., Marionni, S. T., Saifee, N. H., Bush, M. F., et al. (2013). SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature 496, 64-68. doi: 10.1038/nature11964
-
(2013)
Nature
, vol.496
, pp. 64-68
-
-
Xing, W.1
Busino, L.2
Hinds, T.R.3
Marionni, S.T.4
Saifee, N.H.5
Bush, M.F.6
-
50
-
-
0037086535
-
Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein
-
doi: 10.1093/emboj/21.6.1301
-
Yagita, K., Tamanini, F., Yasuda, M., Hoeijmakers, J. H., Van Der Horst, G. T., and Okamura, H. (2002). Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein. EMBO J. 21, 1301-1314. doi: 10.1093/emboj/21.6.1301
-
(2002)
EMBO J.
, vol.21
, pp. 1301-1314
-
-
Yagita, K.1
Tamanini, F.2
Yasuda, M.3
Hoeijmakers, J.H.4
Van Der Horst, G.T.5
Okamura, H.6
-
51
-
-
55449106027
-
Analysis of gene regulatory networks in the mammalian circadian rhythm
-
doi: 10.1371/journal.pcbi.1000193
-
Yan, J., Wang, H., Liu, Y., and Shao, C. (2008). Analysis of gene regulatory networks in the mammalian circadian rhythm. PLoS Comput. Biol. 4:e1000193. doi: 10.1371/journal.pcbi.1000193
-
(2008)
PLoS Comput. Biol.
, vol.4
-
-
Yan, J.1
Wang, H.2
Liu, Y.3
Shao, C.4
-
52
-
-
84964869228
-
Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2
-
doi: 10.1242/bio.20121990
-
Yang, Y., Duguay, D., Bédard, N., Rachalski, A., Baquiran, G., Na, C. H., et al. (2012). Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2. Biol. Open 1, 789-801. doi: 10.1242/bio.20121990
-
(2012)
Biol. Open
, vol.1
, pp. 789-801
-
-
Yang, Y.1
Duguay, D.2
Bédard, N.3
Rachalski, A.4
Baquiran, G.5
Na, C.H.6
-
53
-
-
84905698438
-
USP2 regulates the intracellular localization of PER1 and circadian gene expression
-
(in press)
-
Yang, Y., Duguay, D., Fahrenkrug, J., Cermakian, N., and Wing, S. S. (2014). USP2 regulates the intracellular localization of PER1 and circadian gene expression. J. Biol. Rhythms (in press).
-
(2014)
J. Biol. Rhythms
-
-
Yang, Y.1
Duguay, D.2
Fahrenkrug, J.3
Cermakian, N.4
Wing, S.S.5
-
54
-
-
77954911030
-
E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha
-
doi: 10.1073/pnas.1000438107
-
Yin, L., Joshi, S., Wu, N., Tong, X., and Lazar, M. A. (2010). E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha. Proc. Natl. Acad. Sci. U.S.A. 107, 11614-11619. doi: 10.1073/pnas.1000438107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 11614-11619
-
-
Yin, L.1
Joshi, S.2
Wu, N.3
Tong, X.4
Lazar, M.A.5
-
55
-
-
33144465537
-
Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock
-
doi: 10.1126/science.1121613
-
Yin, L., Wang, J., Klein, P. S., and Lazar, M. A. (2006). Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock. Science 311, 1002-1005. doi: 10.1126/science.1121613
-
(2006)
Science
, vol.311
, pp. 1002-1005
-
-
Yin, L.1
Wang, J.2
Klein, P.S.3
Lazar, M.A.4
-
56
-
-
84874768419
-
Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm
-
doi: 10.1016/j.cell.2013.01.055
-
Yoo, S. H., Mohawk, J. A., Siepka, S. M., Shan, Y., Huh, S. K., Hong, H. K., et al. (2013). Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm. Cell 152, 1091-1105. doi: 10.1016/j.cell.2013.01.055
-
(2013)
Cell
, vol.152
, pp. 1091-1105
-
-
Yoo, S.H.1
Mohawk, J.A.2
Siepka, S.M.3
Shan, Y.4
Huh, S.K.5
Hong, H.K.6
-
57
-
-
84887425535
-
Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3) protein complex
-
doi: 10.1074/jbc.M113.511303
-
Yumimoto, K., Muneoka, T., Tsuboi, T., and Nakayama, K. I. (2013). Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3) protein complex. J. Biol. Chem. 288, 32766-32776. doi: 10.1074/jbc.M113.511303
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 32766-32776
-
-
Yumimoto, K.1
Muneoka, T.2
Tsuboi, T.3
Nakayama, K.I.4
-
58
-
-
84874429128
-
PKCgamma participates in food entrainment by regulating BMAL1
-
doi: 10.1073/pnas.1218699110
-
Zhang, L., Abraham, D., Lin, S. T., Oster, H., Eichele, G., Fu, Y. H., et al. (2012). PKCgamma participates in food entrainment by regulating BMAL1. Proc. Natl. Acad. Sci. U.S.A. 109, 20679-20684. doi: 10.1073/pnas.1218699110
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 20679-20684
-
-
Zhang, L.1
Abraham, D.2
Lin, S.T.3
Oster, H.4
Eichele, G.5
Fu, Y.H.6
|