Pretreatment by evodiamine is neuroprotective in cerebral ischemia: Up-regulated pAkt, pGSK3β, down-regulated NF-κB expression, and ameliorated BBB permeability

Neurochemical Research

Volumn 39, Issue 8, 2014, Pages 1612-1620

  Zhao, Ting ^a   Zhang, Xiangjian ^a,b,c   Zhao, Yuan ^a   Zhang, Lan ^a   Bai, Xue ^a   Zhang, Jian ^a   Zhao, Xumeng ^a   Chen, Linyu ^a   Wang, Lina ^a   Cui, Lili ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Hebei Collaborative Innovation Center for Cardio cerebrovascular Disease   (China)

^c Hebei Key Laboratory for Neurology   (China)

Author keywords

Akt GSK; Claudin 5; Evodiamine; Ischemic stroke; Neuroprotection; NF B

Indexed keywords

EVODIAMINE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROPROTECTIVE AGENT; PLANT EXTRACT; PROTEIN KINASE B; QUINAZOLINE DERIVATIVE;

ANIMAL; BIOSYNTHESIS; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CAPILLARY PERMEABILITY; DOWN REGULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; MALE; METABOLISM; MOUSE; PHYSIOLOGY; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CAPILLARY PERMEABILITY; DOWN-REGULATION; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; MALE; MICE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; QUINAZOLINES; TREATMENT OUTCOME; UP-REGULATION;

EID: 84905709097     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1356-5     Document Type: Article

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