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Volumn 33, Issue 3, 2011, Pages 319-324

Neuroprotection and underlying mechanisms of oxymatrine in cerebral ischemia of rats

Author keywords

Cerebral ischemia; Lipoxygenase; Neuroprotection; Oxymatrine

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; CYTOSOLIC PHOSPHOLIPASE A2; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYMATRINE;

EID: 79955093970     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164110X12759951866876     Document Type: Article
Times cited : (31)

References (26)
  • 1
    • 35648950527 scopus 로고    scopus 로고
    • Cerebral ischemia induces transcription of inflammatory and extracellular-matrix-related genes in rat cerebral arteries
    • Vikman P, Ansar S, Henriksson M, Stenman E, Edvinsson L. Cerebral ischemia induces transcription of inflammatory and extracellular-matrix-related genes in rat cerebral arteries. Exp Brain Res 2007;183:499-510.
    • (2007) Exp Brain Res , vol.183 , pp. 499-510
    • Vikman, P.1    Ansar, S.2    Henriksson, M.3    Stenman, E.4    Edvinsson, L.5
  • 3
    • 31344432053 scopus 로고    scopus 로고
    • Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia
    • Muralikrishna Adibhatla R, Hatcher JF. Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia. Free Radic Biol Med 2006;40:376-87.
    • (2006) Free Radic Biol Med , vol.40 , pp. 376-387
    • Muralikrishna Adibhatla, R.1    Hatcher, J.F.2
  • 4
    • 53149120665 scopus 로고    scopus 로고
    • Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain
    • Farias SE, Basselin M, Chang L, Heidenreich KA, Rapoport SI, Murphy RC. Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain. J Lipid Res 2008;49:1990-2000.
    • (2008) J Lipid Res , vol.49 , pp. 1990-2000
    • Farias, S.E.1    Basselin, M.2    Chang, L.3    Heidenreich, K.A.4    Rapoport, S.I.5    Murphy, R.C.6
  • 5
    • 77949293053 scopus 로고    scopus 로고
    • Oxymatrine downregulates TLR4, TLR2, MyD88, and NFkappaB and protects rat brains against focal ischemia
    • Fan H, Li L, Zhang X, Liu Y, Yang C, Yang Y, et al. Oxymatrine downregulates TLR4, TLR2, MyD88, and NFkappaB and protects rat brains against focal ischemia. Mediators Inflamm 2009;2009:704706.
    • (2009) Mediators Inflamm , vol.2009 , pp. 704-706
    • Fan, H.1    Li, L.2    Zhang, X.3    Liu, Y.4    Yang, C.5    Yang, Y.6
  • 6
    • 67649670106 scopus 로고    scopus 로고
    • Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia
    • Yang C, Zhang X, Fan H, Liu Y. Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res 2009;1282:133-41.
    • (2009) Brain Res , vol.1282 , pp. 133-141
    • Yang, C.1    Zhang, X.2    Fan, H.3    Liu, Y.4
  • 7
    • 52549132911 scopus 로고    scopus 로고
    • Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion
    • Nito C, Kamada H, Endo H, Niizuma K, Myer DJ, Chan PH. Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion. J Cereb Blood Flow Metab 2008;28:1686-96.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1686-1696
    • Nito, C.1    Kamada, H.2    Endo, H.3    Niizuma, K.4    Myer, D.J.5    Chan, P.H.6
  • 8
    • 0042672758 scopus 로고    scopus 로고
    • Citicoline decreases phospholipase A2 stimulation and hydroxyl radical generation in transient cerebral ischemia
    • Adibhatla RM, Hatcher JF. Citicoline decreases phospholipase A2 stimulation and hydroxyl radical generation in transient cerebral ischemia. J Neurosci Res 2003;73:308-15.
    • (2003) J Neurosci Res , vol.73 , pp. 308-315
    • Adibhatla, R.M.1    Hatcher, J.F.2
  • 10
    • 0031471709 scopus 로고    scopus 로고
    • Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2
    • Bonventre JV, Huang Z, Taheri MR, O'Leary E, Li E, Moskowitz MA, et al. Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2. Nature 1997;390:622-5.
    • (1997) Nature , vol.390 , pp. 622-625
    • Bonventre, J.V.1    Huang, Z.2    Taheri, M.R.3    O'Leary, E.4    Li, E.5    Moskowitz, M.A.6
  • 11
    • 1442328269 scopus 로고    scopus 로고
    • Mice deficient in cytosolic phospholipase A2 are less susceptible to cerebral ischemia/reperfusion injury
    • Tabuchi S, Uozumi N, Ishii S, Shimizu Y, Watanabe T, Shimizu T. Mice deficient in cytosolic phospholipase A2 are less susceptible to cerebral ischemia/reperfusion injury. Acta Neurochir Suppl 2003;86:169-72.
    • (2003) Acta Neurochir Suppl , vol.86 , pp. 169-172
    • Tabuchi, S.1    Uozumi, N.2    Ishii, S.3    Shimizu, Y.4    Watanabe, T.5    Shimizu, T.6
  • 12
    • 0036106182 scopus 로고    scopus 로고
    • Effect of oxymatrine on murine fulminant hepatitis and hepatocyte apoptosis
    • Xiang X, Wang G, Cai X, Li Y. Effect of oxymatrine on murine fulminant hepatitis and hepatocyte apoptosis. Chin Med J (Engl) 2002;115:593-6.
    • (2002) Chin Med J (Engl) , vol.115 , pp. 593-596
    • Xiang, X.1    Wang, G.2    Cai, X.3    Li, Y.4
  • 13
  • 14
    • 14844309721 scopus 로고    scopus 로고
    • Attenuation of acute lung injury in mice by oxymatrine is associated with inhibition of phosphorylated p38 mitogenactivated protein kinase
    • Xu GL, Yao L, Rao SY, Gong ZN, Zhang SQ, Yu SQ. Attenuation of acute lung injury in mice by oxymatrine is associated with inhibition of phosphorylated p38 mitogenactivated protein kinase. J Ethnopharmacol 2005;98:177-83.
    • (2005) J Ethnopharmacol , vol.98 , pp. 177-183
    • Xu, G.L.1    Yao, L.2    Rao, S.Y.3    Gong, Z.N.4    Zhang, S.Q.5    Yu, S.Q.6
  • 15
    • 48749105482 scopus 로고    scopus 로고
    • Cardioprotective effects and underlying mechanisms of oxymatrine against Ischemic myocardial injuries of rats
    • Sun HL, Li L, Shang L, Zhao D, Dong DL, Qiao GF, et al. Cardioprotective effects and underlying mechanisms of oxymatrine against Ischemic myocardial injuries of rats. Phytother Res 2008;22:985-9.
    • (2008) Phytother Res , vol.22 , pp. 985-989
    • Sun, H.L.1    Li, L.2    Shang, L.3    Zhao, D.4    Dong, D.L.5    Qiao, G.F.6
  • 16
    • 28244481088 scopus 로고    scopus 로고
    • Anti-apoptosis effects of oxymatrine protect the liver from warm ischemia reperfusion injury in rats
    • Jiang H, Meng F, Li J, Sun X. Anti-apoptosis effects of oxymatrine protect the liver from warm ischemia reperfusion injury in rats. World J Surg 2005;29:1397-401.
    • (2005) World J Surg , vol.29 , pp. 1397-1401
    • Jiang, H.1    Meng, F.2    Li, J.3    Sun, X.4
  • 17
    • 64149117795 scopus 로고    scopus 로고
    • Oxymatrine protects rat brains against permanent focal ischemia and downregulates NF-kappaB expression
    • Liu Y, Zhang XJ, Yang CH, Fan HG. Oxymatrine protects rat brains against permanent focal ischemia and downregulates NF-kappaB expression. Brain Res 2009;1268:174-80.
    • (2009) Brain Res , vol.1268 , pp. 174-180
    • Liu, Y.1    Zhang, X.J.2    Yang, C.H.3    Fan, H.G.4
  • 18
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989;20:84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 19
    • 77949913306 scopus 로고    scopus 로고
    • Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: Down-regulated 12/15- LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability
    • Cui L, Zhang L, Yang L, Wang L, Liu L, Li M, et al. Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15- LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability. Brain Res 2010;1325:164-73.
    • (2010) Brain Res , vol.1325 , pp. 164-173
    • Cui, L.1    Zhang, L.2    Yang, L.3    Wang, L.4    Liu, L.5    Li, M.6
  • 21
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med 2009;7:97.
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 22
    • 0028220499 scopus 로고
    • Proinflammatory cytokines in serum of patients with acute cerebral ischemia: Kinetics of secretion and relation to the extent of brain damage and outcome of disease
    • Fassbender K, Rossol S, Kammer T, Daffertshofer M, Wirth S, Hennerici M. Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci 1994;122:135-9.
    • (1994) J Neurol Sci , vol.122 , pp. 135-139
    • Fassbender, K.1    Rossol, S.2    Kammer, T.3    Daffertshofer, M.4    Wirth, S.5    Hennerici, M.6
  • 23
    • 0020522819 scopus 로고
    • Cortical oxidative metabolism under conditions of ischemia, hypoxia, and asphyxia in the rabbit
    • Koga H, Austin G. Cortical oxidative metabolism under conditions of ischemia, hypoxia, and asphyxia in the rabbit. J Neurosurg 1983;59:57-62.
    • (1983) J Neurosurg , vol.59 , pp. 57-62
    • Koga, H.1    Austin, G.2
  • 25
    • 52949129442 scopus 로고    scopus 로고
    • Oxymatrine attenuates intestinal ischemia/reperfusion injury in rats
    • Zhao J, Yu S, Tong L, Zhang F, Jiang X, Pan S, et al. Oxymatrine attenuates intestinal ischemia/reperfusion injury in rats. Surg Today 2008;38:931-7.
    • (2008) Surg Today , vol.38 , pp. 931-937
    • Zhao, J.1    Yu, S.2    Tong, L.3    Zhang, F.4    Jiang, X.5    Pan, S.6
  • 26
    • 0036435794 scopus 로고    scopus 로고
    • Effects of oxymatrine on the serum levels of T helper cell 1 and 2 cytokines and the expression of the S gene in hepatitis B virus S gene transgenic mice: A study on the anti-hepatitis B virus mechanism of oxymatrine
    • Dong Y, Xi H, Yu Y, Wang Q, Jiang K, Li L. Effects of oxymatrine on the serum levels of T helper cell 1 and 2 cytokines and the expression of the S gene in hepatitis B virus S gene transgenic mice: a study on the anti-hepatitis B virus mechanism of oxymatrine. J Gastroenterol Hepatol 2002;17:1299-306.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 1299-1306
    • Dong, Y.1    Xi, H.2    Yu, Y.3    Wang, Q.4    Jiang, K.5    Li, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.