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Volumn 16, Issue 8, 2014, Pages 758-769

Par3-mInsc and Gα i3 cooperate to promote oriented epidermal cell divisions through LGN

Author keywords

[No Author keywords available]

Indexed keywords

G ALPHA I3 PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LGN PROTEIN; MLNSC PROTEIN; PAR3 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CELL ADHESION MOLECULE; CELL CYCLE PROTEIN; GNAI2 PROTEIN, MOUSE; GNAI3 PROTEIN, MOUSE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INSCUTEABLE PROTEIN, MOUSE; LGN PROTEIN, MOUSE; PARD3 PROTEIN, MOUSE;

EID: 84905511560     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3001     Document Type: Article
Times cited : (104)

References (64)
  • 1
    • 33947104197 scopus 로고    scopus 로고
    • A single type of progenitor cell maintains normal epidermis
    • Clayton, E. et al. A single type of progenitor cell maintains normal epidermis. Nature 446, 185-189 (2007).
    • (2007) Nature , vol.446 , pp. 185-189
    • Clayton, E.1
  • 2
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler, T. & Fuchs, E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 437, 275-280 (2005).
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 3
    • 0014759983 scopus 로고
    • Variation in the plane of cell cleavage during the process of stratification in the mouse epidermis
    • Smart, I. H. Variation in the plane of cell cleavage during the process of stratification in the mouse epidermis. Br. J. Dermatol. 82, 276-282 (1970).
    • (1970) Br. J. Dermatol. , vol.82 , pp. 276-282
    • Smart, I.H.1
  • 4
    • 84887625002 scopus 로고    scopus 로고
    • Oriented divisions, fate decisions
    • Williams, S. E. & Fuchs, E. Oriented divisions, fate decisions. Curr. Opin. Cell Biol. 25, 749-758 (2013).
    • (2013) Curr. Opin. Cell Biol. , vol.25 , pp. 749-758
    • Williams, S.E.1    Fuchs, E.2
  • 5
    • 39149130360 scopus 로고    scopus 로고
    • Mechanisms of asymmetric stem cell division
    • Knoblich, J. A. Mechanisms of asymmetric stem cell division. Cell 132, 583-597 (2008).
    • (2008) Cell , vol.132 , pp. 583-597
    • Knoblich, J.A.1
  • 6
    • 64049088018 scopus 로고    scopus 로고
    • Spindle orientation during asymmetric cell division
    • Siller, K. H. & Doe, C. Q. Spindle orientation during asymmetric cell division. Nat. Cell Biol. 11, 365-374 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , pp. 365-374
    • Siller, K.H.1    Doe, C.Q.2
  • 7
    • 8344221351 scopus 로고    scopus 로고
    • Asymmetric cell division in C. Elegans: Cortical polarity and spindle positioning
    • Cowan, C. R. & Hyman, A. A. Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. Annu. Rev. Cell Dev. Biol. 20, 427-453 (2004).
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 427-453
    • Cowan, C.R.1    Hyman, A.A.2
  • 8
    • 84655169623 scopus 로고    scopus 로고
    • Epithelial cell polarity, stem cells and cancer
    • Martin-Belmonte, F. & Perez-Moreno, M. Epithelial cell polarity, stem cells and cancer. Nat. Rev. Cancer 12, 23-38 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 23-38
    • Martin-Belmonte, F.1    Perez-Moreno, M.2
  • 9
    • 78649439321 scopus 로고    scopus 로고
    • Asymmetric cell division: Recent developments and their implications for tumour biology
    • Knoblich, J. A. Asymmetric cell division: recent developments and their implications for tumour biology. Nat. Rev. Mol. Cell Biol. 11, 849-860 (2010).
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 849-860
    • Knoblich, J.A.1
  • 10
    • 34249018619 scopus 로고    scopus 로고
    • Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells
    • Gonzalez, C. Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells. Nat. Rev. Genet. 8, 462-472 (2007).
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 462-472
    • Gonzalez, C.1
  • 11
    • 84868545441 scopus 로고    scopus 로고
    • Drosophila neuroblasts: A model for stem cell biology
    • Homem, C. C. & Knoblich, J. A. Drosophila neuroblasts: a model for stem cell biology. Development 139, 4297-4310 (2012).
    • (2012) Development , vol.139 , pp. 4297-4310
    • Homem, C.C.1    Knoblich, J.A.2
  • 12
    • 77955479116 scopus 로고    scopus 로고
    • Polarization of Drosophila neuroblasts during asymmetric division
    • Prehoda, K. E. Polarization of Drosophila neuroblasts during asymmetric division. Cold Spring Harb. Perspect. Biol. 1, a001388 (2009).
    • (2009) Cold Spring Harb. Perspect. Biol. , vol.1
    • Prehoda, K.E.1
  • 13
    • 84855487476 scopus 로고    scopus 로고
    • Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions
    • Culurgioni, S., Alfieri, A., Pendolino, V., Laddomada, F. & Mapelli, M. Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions. Proc. Natl Acad. Sci. USA 108, 20998-21003 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 20998-21003
    • Culurgioni, S.1    Alfieri, A.2    Pendolino, V.3    Laddomada, F.4    Mapelli, M.5
  • 14
    • 84855573224 scopus 로고    scopus 로고
    • Inscuteable regulates the Pins-Mud spindle orientation pathway
    • Mauser, J. F. & Prehoda, K. E. Inscuteable regulates the Pins-Mud spindle orientation pathway. PLoS ONE 7, e29611 (2012).
    • (2012) PLoS ONE , vol.7
    • Mauser, J.F.1    Prehoda, K.E.2
  • 15
    • 82755163576 scopus 로고    scopus 로고
    • Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)
    • Yuzawa, S., Kamakura, S., Iwakiri, Y., Hayase, J. & Sumimoto, H. Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN). Proc. Natl Acad. Sci. USA 108, 19210-19215 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 19210-19215
    • Yuzawa, S.1    Kamakura, S.2    Iwakiri, Y.3    Hayase, J.4    Sumimoto, H.5
  • 16
    • 79960913555 scopus 로고    scopus 로고
    • LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G-i/LGN/NuMA pathways
    • Zhu, J. et al. LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G-i/LGN/NuMA pathways. Mol. Cell 43, 418-431 (2011).
    • (2011) Mol. Cell , vol.43 , pp. 418-431
    • Zhu, J.1
  • 17
    • 79951784680 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote Notch-dependent epidermal differentiation
    • Williams, S. E., Beronja, S., Pasolli, H. A. & Fuchs, E. Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature 470, 353-358 (2011).
    • (2011) Nature , vol.470 , pp. 353-358
    • Williams, S.E.1    Beronja, S.2    Pasolli, H.A.3    Fuchs, E.4
  • 18
    • 78751512485 scopus 로고    scopus 로고
    • Cell polarity and spindle orientation in the distal epithelium of embryonic lung
    • El-Hashash, A. H. & Warburton, D. Cell polarity and spindle orientation in the distal epithelium of embryonic lung. Dev. Dyn. 240, 441-445 (2011).
    • (2011) Dev. Dyn. , vol.240 , pp. 441-445
    • El-Hashash, A.H.1    Warburton, D.2
  • 19
    • 37749022460 scopus 로고    scopus 로고
    • Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis
    • Konno, D. et al. Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat. Cell Biol. 10, 93-101 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , pp. 93-101
    • Konno, D.1
  • 20
    • 79955497378 scopus 로고    scopus 로고
    • A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells
    • Peyre, E. et al. A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells. J. Cell Biol. 193, 141-154 (2011).
    • (2011) J. Cell Biol. , vol.193 , pp. 141-154
    • Peyre, E.1
  • 21
    • 79952282364 scopus 로고    scopus 로고
    • Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation
    • Luxenburg, C., Amalia Pasolli, H., Williams, S. E. & Fuchs, E. Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation. Nat. Cell Biol. 13, 203-214 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 203-214
    • Luxenburg, C.1    Amalia Pasolli, H.2    Williams, S.E.3    Fuchs, E.4
  • 22
    • 78649671270 scopus 로고    scopus 로고
    • Robust control of mitotic spindle orientation in the developing epidermis
    • Poulson, N. D. & Lechler, T. Robust control of mitotic spindle orientation in the developing epidermis. J. Cell Biol. 191, 915-922 (2010).
    • (2010) J. Cell Biol. , vol.191 , pp. 915-922
    • Poulson, N.D.1    Lechler, T.2
  • 23
    • 78149476036 scopus 로고    scopus 로고
    • The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex
    • Gladden, A. B., Hebert, A. M., Schneeberger, E. E. & McClatchey, A. I. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev. Cell 19, 727-739 (2010).
    • (2010) Dev. Cell , vol.19 , pp. 727-739
    • Gladden, A.B.1    Hebert, A.M.2    Schneeberger, E.E.3    McClatchey, A.I.4
  • 24
    • 0020080826 scopus 로고
    • Stratification and terminal differentiation of cultured epidermal cells
    • Watt, F. M. & Green, H. Stratification and terminal differentiation of cultured epidermal cells. Nature 295, 434-436 (1982).
    • (1982) Nature , vol.295 , pp. 434-436
    • Watt, F.M.1    Green, H.2
  • 25
    • 0029666420 scopus 로고    scopus 로고
    • Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival
    • Dowling, J., Yu, Q. C. & Fuchs, E. Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J. Cell Biol. 134, 559-572 (1996).
    • (1996) J. Cell Biol. , vol.134 , pp. 559-572
    • Dowling, J.1    Yu, Q.C.2    Fuchs, E.3
  • 26
    • 84879293921 scopus 로고    scopus 로고
    • RNAi-mediated gene function analysis in skin
    • Beronja, S. & Fuchs, E. RNAi-mediated gene function analysis in skin. Methods Mol. Biol. 961, 351-361 (2013).
    • (2013) Methods Mol. Biol. , vol.961 , pp. 351-361
    • Beronja, S.1    Fuchs, E.2
  • 27
    • 77954534273 scopus 로고    scopus 로고
    • Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos
    • Beronja, S., Livshits, G., Williams, S. & Fuchs, E. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat. Med. 16, 821-827 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 821-827
    • Beronja, S.1    Livshits, G.2    Williams, S.3    Fuchs, E.4
  • 28
    • 77957223906 scopus 로고    scopus 로고
    • Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
    • Snippert, H. J. et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 143, 134-144 (2010).
    • (2010) Cell , vol.143 , pp. 134-144
    • Snippert, H.J.1
  • 29
    • 84878697527 scopus 로고    scopus 로고
    • Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis
    • Kawaguchi, D., Furutachi, S., Kawai, H., Hozumi, K. & Gotoh, Y. Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis. Nat. Commun. 4, 1880 (2013).
    • (2013) Nat. Commun. , vol.4 , pp. 1880
    • Kawaguchi, D.1    Furutachi, S.2    Kawai, H.3    Hozumi, K.4    Gotoh, Y.5
  • 30
    • 79955165310 scopus 로고    scopus 로고
    • Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium
    • El-Hashash, A. H. et al. Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development 138, 1395-1407 (2011).
    • (2011) Development , vol.138 , pp. 1395-1407
    • El-Hashash, A.H.1
  • 31
    • 67650898238 scopus 로고    scopus 로고
    • Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex
    • Bultje, R. S. et al. Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron 63, 189-202 (2009).
    • (2009) Neuron , vol.63 , pp. 189-202
    • Bultje, R.S.1
  • 32
    • 45149117788 scopus 로고    scopus 로고
    • Notch-deficient skin induces a lethal systemic Blymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity
    • Demehri, S. et al. Notch-deficient skin induces a lethal systemic Blymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity. PLoS Biol. 6, e123 (2008).
    • (2008) PLoS Biol. , vol.6
    • Demehri, S.1
  • 33
    • 0034611690 scopus 로고    scopus 로고
    • A protein complex containing Inscuteable and the G-binding protein Pins orients asymmetric cell divisions in Drosophila
    • Schaefer, M., Shevchenko, A. & Knoblich, J. A. A protein complex containing Inscuteable and the G-binding protein Pins orients asymmetric cell divisions in Drosophila. Curr. Biol. 10, 353-362 (2000).
    • (2000) Curr. Biol. , vol.10 , pp. 353-362
    • Schaefer, M.1    Shevchenko, A.2    Knoblich, J.A.3
  • 34
    • 0034681261 scopus 로고    scopus 로고
    • Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization
    • Yu, F., Morin, X., Cai, Y., Yang, X. & Chia, W. Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. Cell 100, 399-409 (2000).
    • (2000) Cell , vol.100 , pp. 399-409
    • Yu, F.1    Morin, X.2    Cai, Y.3    Yang, X.4    Chia, W.5
  • 35
    • 3943109350 scopus 로고    scopus 로고
    • Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila
    • Parmentier, M. L. et al. Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila. J. Neurosci. 20, RC84 (2000).
    • (2000) J. Neurosci. , vol.20
    • Parmentier, M.L.1
  • 36
    • 80054841867 scopus 로고    scopus 로고
    • Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex
    • Postiglione, M. P. et al. Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron 72, 269-284 (2011).
    • (2011) Neuron , vol.72 , pp. 269-284
    • Postiglione, M.P.1
  • 37
    • 0033518187 scopus 로고    scopus 로고
    • Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts
    • Schober, M., Schaefer, M. & Knoblich, J. A. Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature 402, 548-551 (1999).
    • (1999) Nature , vol.402 , pp. 548-551
    • Schober, M.1    Schaefer, M.2    Knoblich, J.A.3
  • 38
    • 0033518223 scopus 로고    scopus 로고
    • Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts
    • Wodarz, A., Ramrath, A., Kuchinke, U. & Knust, E. Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts. Nature 402, 544-547 (1999).
    • (1999) Nature , vol.402 , pp. 544-547
    • Wodarz, A.1    Ramrath, A.2    Kuchinke, U.3    Knust, E.4
  • 39
    • 78049255724 scopus 로고    scopus 로고
    • Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
    • Hao, Y. et al. Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr. Biol. 20, 1809-1818 (2010).
    • (2010) Curr. Biol. , vol.20 , pp. 1809-1818
    • Hao, Y.1
  • 40
    • 33646127606 scopus 로고    scopus 로고
    • PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains
    • Hirose, T. et al. PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development 133, 1389-1398 (2006).
    • (2006) Development , vol.133 , pp. 1389-1398
    • Hirose, T.1
  • 41
    • 0037055254 scopus 로고    scopus 로고
    • Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties
    • Gao, L., Macara, I. G. & Joberty, G. Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties. Gene 294, 99-107 (2002).
    • (2002) Gene , vol.294 , pp. 99-107
    • Gao, L.1    Macara, I.G.2    Joberty, G.3
  • 42
    • 0036882125 scopus 로고    scopus 로고
    • PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions
    • Kohjima, M. et al. PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions. Biochem. Biophys. Res. Commun. 299, 641-646 (2002).
    • (2002) Biochem. Biophys. Res. Commun. , vol.299 , pp. 641-646
    • Kohjima, M.1
  • 43
    • 8344271193 scopus 로고    scopus 로고
    • Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins
    • Du, Q. & Macara, I. G. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell 119, 503-516 (2004).
    • (2004) Cell , vol.119 , pp. 503-516
    • Du, Q.1    Macara, I.G.2
  • 44
    • 84878879179 scopus 로고    scopus 로고
    • An autoinhibited conformation of LGN reveals a distinct interaction mode between goloco motifs and TPR motifs
    • Pan, Z. et al. An autoinhibited conformation of LGN reveals a distinct interaction mode between goloco motifs and TPR motifs. Structure 21, 1007-1017 (2013).
    • (2013) Structure , vol.21 , pp. 1007-1017
    • Pan, Z.1
  • 45
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for G and G in regulating spindle position and orientation in Caenorhabditis elegans embryos
    • Gotta, M. & Ahringer, J. Distinct roles for G and G in regulating spindle position and orientation in Caenorhabditis elegans embryos. Nat. Cell Biol. 3, 297-300 (2001).
    • (2001) Nat. Cell Biol. , vol.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 46
    • 0038046388 scopus 로고    scopus 로고
    • Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos
    • Colombo, K. et al. Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science 300, 1957-1961 (2003).
    • (2003) Science , vol.300 , pp. 1957-1961
    • Colombo, K.1
  • 47
    • 0037948857 scopus 로고    scopus 로고
    • A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans
    • Srinivasan, D. G., Fisk, R. M., Xu, H. & van den Heuvel, S. A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans. Genes Dev. 17, 1225-1239 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 1225-1239
    • Srinivasan, D.G.1    Fisk, R.M.2    Xu, H.3    Van Den Heuvel, S.4
  • 48
    • 0037428199 scopus 로고    scopus 로고
    • Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions
    • Cai, Y., Yu, F., Lin, S., Chia, W. & Yang, X. Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell 112, 51-62 (2003).
    • (2003) Cell , vol.112 , pp. 51-62
    • Cai, Y.1    Yu, F.2    Lin, S.3    Chia, W.4    Yang, X.5
  • 49
    • 0041977037 scopus 로고    scopus 로고
    • Distinct roles of G-i and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions
    • Yu, F., Cai, Y., Kaushik, R., Yang, X. & Chia, W. Distinct roles of G-i and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. J. Cell Biol. 162, 623-633 (2003).
    • (2003) J. Cell Biol. , vol.162 , pp. 623-633
    • Yu, F.1    Cai, Y.2    Kaushik, R.3    Yang, X.4    Chia, W.5
  • 50
    • 22144436963 scopus 로고    scopus 로고
    • G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors
    • Sanada, K. & Tsai, L. H. G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors. Cell 122, 119-131 (2005).
    • (2005) Cell , vol.122 , pp. 119-131
    • Sanada, K.1    Tsai, L.H.2
  • 51
    • 0035913905 scopus 로고    scopus 로고
    • Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system
    • Schaefer, M., Petronczki, M., Dorner, D., Forte, M. & Knoblich, J. A. Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell 107, 183-194 (2001).
    • (2001) Cell , vol.107 , pp. 183-194
    • Schaefer, M.1    Petronczki, M.2    Dorner, D.3    Forte, M.4    Knoblich, J.A.5
  • 52
    • 67651036549 scopus 로고    scopus 로고
    • The glial nature of embryonic and adult neural stem cells
    • Kriegstein, A. & Alvarez-Buylla, A. The glial nature of embryonic and adult neural stem cells. Annu. Rev. Neurosci. 32, 149-184 (2009).
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 149-184
    • Kriegstein, A.1    Alvarez-Buylla, A.2
  • 53
    • 84860244323 scopus 로고    scopus 로고
    • Control of asymmetric cell division of mammalian neural progenitors
    • Shitamukai, A. & Matsuzaki, F. Control of asymmetric cell division of mammalian neural progenitors. Dev. Growth Differ. 54, 277-286 (2012).
    • (2012) Dev. Growth Differ. , vol.54 , pp. 277-286
    • Shitamukai, A.1    Matsuzaki, F.2
  • 54
    • 35548951453 scopus 로고    scopus 로고
    • Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium
    • Morin, X., Jaouen, F. & Durbec, P. Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium. Nat. Neurosci. 10, 1440-1448 (2007).
    • (2007) Nat. Neurosci. , vol.10 , pp. 1440-1448
    • Morin, X.1    Jaouen, F.2    Durbec, P.3
  • 55
    • 84868212666 scopus 로고    scopus 로고
    • Spindle orientation in mammalian cerebral cortical development
    • Lancaster, M. A. & Knoblich, J. A. Spindle orientation in mammalian cerebral cortical development. Curr. Opin. Neurobiol. 22, 737-746 (2012).
    • (2012) Curr. Opin. Neurobiol. , vol.22 , pp. 737-746
    • Lancaster, M.A.1    Knoblich, J.A.2
  • 56
    • 84867363816 scopus 로고    scopus 로고
    • The par complex and integrins direct asymmetric cell division in adult intestinal stem cells
    • Goulas, S., Conder, R. & Knoblich, J. A. The par complex and integrins direct asymmetric cell division in adult intestinal stem cells. Cell Stem Cell 11, 529-540 (2012).
    • (2012) Cell Stem Cell , vol.11 , pp. 529-540
    • Goulas, S.1    Conder, R.2    Knoblich, J.A.3
  • 57
    • 84884375041 scopus 로고    scopus 로고
    • APKClambda controls epidermal homeostasis and stem cell fate through regulation of division orientation
    • Niessen, M. T. et al. aPKClambda controls epidermal homeostasis and stem cell fate through regulation of division orientation. J. Cell Biol. 202, 887-900 (2013).
    • (2013) J. Cell Biol. , vol.202 , pp. 887-900
    • Niessen, M.T.1
  • 58
    • 79960207659 scopus 로고    scopus 로고
    • Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development
    • Morin, X. & Bellaiche, Y. Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development. Dev. Cell 21, 102-119 (2011).
    • (2011) Dev. Cell , vol.21 , pp. 102-119
    • Morin, X.1    Bellaiche, Y.2
  • 59
    • 67349204759 scopus 로고    scopus 로고
    • Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division
    • Coumailleau, F., Furthauer, M., Knoblich, J. A. & Gonzalez-Gaitan, M. Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature 458, 1051-1055 (2009).
    • (2009) Nature , vol.458 , pp. 1051-1055
    • Coumailleau, F.1    Furthauer, M.2    Knoblich, J.A.3    Gonzalez-Gaitan, M.4
  • 60
    • 65549085440 scopus 로고    scopus 로고
    • Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi
    • Mummery-Widmer, J. L. et al. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature 458, 987-992 (2009).
    • (2009) Nature , vol.458 , pp. 987-992
    • Mummery-Widmer, J.L.1
  • 61
    • 84864280567 scopus 로고    scopus 로고
    • Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration
    • Rompolas, P. et al. Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration. Nature 487, 496-499 (2012).
    • (2012) Nature , vol.487 , pp. 496-499
    • Rompolas, P.1
  • 62
    • 84866037962 scopus 로고    scopus 로고
    • Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis
    • Iden, S. et al. Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis. Cancer Cell 22, 389-403 (2012).
    • (2012) Cancer Cell , vol.22 , pp. 389-403
    • Iden, S.1
  • 63
    • 0036094254 scopus 로고    scopus 로고
    • Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells
    • Tanigaki, K. et al. Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nat. Immunol. 3, 443-450 (2002).
    • (2002) Nat. Immunol. , vol.3 , pp. 443-450
    • Tanigaki, K.1
  • 64
    • 59749096851 scopus 로고    scopus 로고
    • Isolation and culture of epithelial stem cells
    • Nowak, J. A. & Fuchs, E. Isolation and culture of epithelial stem cells. Methods Mol. Biol. 482, 215-232 (2009).
    • (2009) Methods Mol. Biol. , vol.482 , pp. 215-232
    • Nowak, J.A.1    Fuchs, E.2


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