Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies

Journal of Molecular Biology

Volumn 426, Issue 17, 2014, Pages 3057-3068

  Rudolph, Michael J ^a   Vance, David J ^b   Cheung, Jonah ^a   Franklin, Matthew C ^a   Burshteyn, Fiana ^a   Cassidy, Michael S ^a   Gary, Ebony N ^a   Herrera, Cristina ^b,c   Shoemaker, Charles B ^d   Mantis, Nicholas J ^b,c  

^a NEW YORK STRUCTURAL BIOLOGY CENTER   (United States)

^b WADSWORTH CENTER   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d TUFTS UNIVERSITY   (United States)

Author keywords

antibody; nanobody; neutralizing; toxin

Indexed keywords

EPITOPE; GLYCOSIDASE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RICIN; RICIN CATALYTIC A SUBUNIT; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SUBUNIT VACCINE; UNCLASSIFIED DRUG; RNA;

ALLOSTERISM; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; COMPLEMENTARITY DETERMINING REGION; CRYSTAL STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; ENZYME ACTIVITY; MOLECULAR INTERACTION; SURFACE PROPERTY; VERO CELL LINE;

BACTERIA (MICROORGANISMS);

ANTIBODY; NANOBODY; NEUTRALIZING; TOXIN;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEUTRALIZING; CAMELS; CASTOR BEAN; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RICIN; SINGLE-CHAIN ANTIBODIES;

EID: 84905510170     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.05.026     Document Type: Article

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