Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit

Toxicon

Volumn 60, Issue 5, 2012, Pages 874-877

  Vance, David J ^a   Mantis, Nicholas J ^a,b  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY AT ALBANY   (United States)

Author keywords

B cell epitope; Neutralizing antibodies; Phage display; Toxin

Indexed keywords

EPITOPE; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PB10 ANTIBODY; R70 ANTIBODY; RICIN; SOLVENT; THREONINE; TOXIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; NONHUMAN; PEPTIDE LIBRARY; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; CATALYTIC DOMAIN; EPITOPES, B-LYMPHOCYTE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN STRUCTURE, SECONDARY; RICIN;

EID: 84864055517     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.06.014     Document Type: Article

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