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Volumn 20, Issue 6, 2013, Pages 789-794

Comparative efficacy of two leading candidate ricin toxin A subunit vaccines in mice

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM HYDROXIDE; AMINO ACID; IMMUNOGLOBULIN G ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT VACCINE; RICIN; RICIN TOXIN A SUBUNIT VACCINE; RIVAX VACCINE; RVEC VACCINE; UNCLASSIFIED DRUG;

EID: 84878303015     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00098-13     Document Type: Article
Times cited : (29)

References (34)
  • 1
    • 0023219950 scopus 로고
    • RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes
    • Endo Y, Tsurugi K. 1987. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. J. Biol. Chem. 262:8128-8130. (Pubitemid 17104265)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.17 , pp. 8128-8130
    • Endo, Y.1    Tsurugi, K.2
  • 2
    • 0023091105 scopus 로고
    • Structure and evolution of ricin B chain
    • DOI 10.1038/326624a0
    • Rutenber E, Ready M, Robertus JD. 1987. Structure and evolution of ricin B chain. Nature 326:624-626. (Pubitemid 17051336)
    • (1987) Nature , vol.326 , Issue.6113 , pp. 624-626
    • Rutenber, E.1    Ready, M.2    Robertus, J.D.3
  • 3
    • 0002954612 scopus 로고    scopus 로고
    • Ricin toxin
    • Zajtchuk R (ed), Borden Institute, Washington, DC
    • Franz D, Jaax N. 1997. Ricin toxin, p 631-642. In Zajtchuk R (ed), Textbook of military medicine. Borden Institute, Washington, DC.
    • (1997) Textbook of Military Medicine , pp. 631-642
    • Franz, D.1    Jaax, N.2
  • 5
    • 84873527715 scopus 로고    scopus 로고
    • The need for continued development of ricin countermeasures
    • doi:10.1155/2012/149737
    • Reisler RB, Smith LA. 2012. The need for continued development of ricin countermeasures. Adv. Prev. Med. 2012:149737. doi:10.1155/2012/149737.
    • (2012) Adv. Prev. Med. , vol.2012 , pp. 149737
    • Reisler, R.B.1    Smith, L.A.2
  • 6
    • 2442626550 scopus 로고    scopus 로고
    • Immunological Characteristics Associated with the Protective Efficacy of Antibodies to Ricin
    • Maddaloni M, Cooke C, Wilkinson R, Stout AV, Eng L, Pincus SH. 2004. Immunological characteristics associated with the protective efficacy of antibodies to ricin. J. Immunol. 172:6221-6228. (Pubitemid 38621228)
    • (2004) Journal of Immunology , vol.172 , Issue.10 , pp. 6221-6228
    • Maddaloni, M.1    Cooke, C.2    Wilkinson, R.3    Stout, A.V.4    Eng, L.5    Pincus, S.H.6
  • 7
    • 80053636763 scopus 로고    scopus 로고
    • Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB)
    • Yermakova A, Mantis NJ. 2011. Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB). Vaccine 29:7925-7935.
    • (2011) Vaccine , vol.29 , pp. 7925-7935
    • Yermakova, A.1    Mantis, N.J.2
  • 9
    • 0037056037 scopus 로고    scopus 로고
    • A novel recombinant vaccine which protects mice against ricin intoxication
    • DOI 10.1016/S0264-410X(02)00312-2, PII S0264410X02003122
    • Smallshaw JE, Firan A, Fulmer JR, Ruback SL, Ghetie V, Vitetta ES. 2002. A novel recombinant vaccine which protects mice against ricin intoxication. Vaccine 20:3422-3427. (Pubitemid 35245826)
    • (2002) Vaccine , vol.20 , Issue.27-28 , pp. 3422-3427
    • Smallshaw, J.E.1    Firan, A.2    Fulmer, J.R.3    Ruback, S.L.4    Ghetie, V.5    Vitetta, E.S.6
  • 11
    • 34247326598 scopus 로고    scopus 로고
    • Improved formulation of a recombinant ricin A-chain vaccine increases its stability and effective antigenicity
    • DOI 10.1016/j.vaccine.2007.03.011, PII S0264410X07003040
    • Carra JH, Wannemacher RW, Tammariello RF, Lindsey CY, Dinterman RE, Schokman RD, Smith LA. 2007. Improved formulation of a recombinant ricin A-chain vaccine increases its stability and effective antigenicity. Vaccine 25:4149-4158. (Pubitemid 46635951)
    • (2007) Vaccine , vol.25 , Issue.21 , pp. 4149-4158
    • Carra, J.H.1    Wannemacher, R.W.2    Tammariello, R.F.3    Lindsey, C.Y.4    Dinterman, R.E.5    Schokman, R.D.6    Smith, L.A.7
  • 12
    • 4143060688 scopus 로고    scopus 로고
    • Improved stability of a protein vaccine through elimination of a partially unfolded state
    • DOI 10.1110/ps.04897904
    • McHugh CA, Tammariello RF, Millard CB, Carra JH. 2004. Improved stability of a protein vaccine through elimination of a partially unfolded state. Protein Sci. 13:2736-2743. (Pubitemid 39274641)
    • (2004) Protein Science , vol.13 , Issue.10 , pp. 2736-2743
    • McHugh, C.A.1    Tammariello, R.F.2    Millard, C.B.3    Carra, J.H.4
  • 15
    • 77954958642 scopus 로고    scopus 로고
    • Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication
    • Marconescu PS, Smallshaw JE, Pop LM, Ruback SL, Vitetta ES. 2010. Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication. Vaccine 28:5315-5322.
    • (2010) Vaccine , vol.28 , pp. 5315-5322
    • Marconescu, P.S.1    Smallshaw, J.E.2    Pop, L.M.3    Ruback, S.L.4    Vitetta, E.S.5
  • 16
    • 25144493280 scopus 로고    scopus 로고
    • Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin
    • DOI 10.1016/j.vaccine.2005.04.037
    • Smallshaw JE, Richardson JA, Pincus S, Schindler J, Vitetta ES. 2005. Preclinical toxicity and efficacy testing of RiVax, a recombinant protein vaccine against ricin. Vaccine 23:4775-4784. (Pubitemid 41557328)
    • (2005) Vaccine , vol.23 , Issue.39 , pp. 4775-4784
    • Smallshaw, J.E.1    Richardson, J.A.2    Pincus, S.3    Schindler, J.4    Vitetta, E.S.5
  • 17
    • 34748918488 scopus 로고    scopus 로고
    • RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol
    • DOI 10.1016/j.vaccine.2007.08.018, PII S0264410X07009139
    • Smallshaw JE, Richardson JA, Vitetta ES. 2007. RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol. Vaccine 25:7459-7469. (Pubitemid 47484003)
    • (2007) Vaccine , vol.25 , Issue.42 , pp. 7459-7469
    • Smallshaw, J.E.1    Richardson, J.A.2    Vitetta, E.S.3
  • 19
    • 84867241458 scopus 로고    scopus 로고
    • Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine
    • Vitetta ES, Smallshaw JE, Schindler J. 2012. Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine. Clin. Vaccine Immunol. 19:1697-1699.
    • (2012) Clin. Vaccine Immunol. , vol.19 , pp. 1697-1699
    • Vitetta, E.S.1    Smallshaw, J.E.2    Schindler, J.3
  • 20
    • 79955635252 scopus 로고    scopus 로고
    • Progress in biological threat agent vaccine development: A repeat-dose toxicity study of a recombinant ricin toxin A-chain (rRTA) 1-33/44-198 vaccine (RVEc) in male and female New Zealand white rabbits
    • McLain DE, Horn TL, Detrisac CJ, Lindsey CY, Smith LA. 2011. Progress in biological threat agent vaccine development: a repeat-dose toxicity study of a recombinant ricin toxin A-chain (rRTA) 1-33/44-198 vaccine (RVEc) in male and female New Zealand white rabbits. Int. J. Toxicol. 30:143-152.
    • (2011) Int. J. Toxicol. , vol.30 , pp. 143-152
    • McLain, D.E.1    Horn, T.L.2    Detrisac, C.J.3    Lindsey, C.Y.4    Smith, L.A.5
  • 21
    • 84863393032 scopus 로고    scopus 로고
    • Protective effect of two recombinant ricin subunit vaccines in the New Zealand White rabbit subjected to a lethal aerosolized ricin challenge: Survival, immunological response and histopathological findings
    • McLain DE, Lewis BS, Chapman JL, Wannemacher RW, Lindsey CY, Smith LA. 2012. Protective effect of two recombinant ricin subunit vaccines in the New Zealand White rabbit subjected to a lethal aerosolized ricin challenge: survival, immunological response and histopathological findings. Toxicol. Sci. 126:72-83.
    • (2012) Toxicol. Sci. , vol.126 , pp. 72-83
    • McLain, D.E.1    Lewis, B.S.2    Chapman, J.L.3    Wannemacher, R.W.4    Lindsey, C.Y.5    Smith, L.A.6
  • 23
    • 79959374624 scopus 로고    scopus 로고
    • Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay
    • Porter A, Phillips G, Smith L, Erwin-Cohen R, Tammariello R, Hale M, Dasilva L. 2011. Evaluation of a ricin vaccine candidate (RVEc) for human toxicity using an in vitro vascular leak assay. Toxicon 58:68-75.
    • (2011) Toxicon , vol.58 , pp. 68-75
    • Porter, A.1    Phillips, G.2    Smith, L.3    Erwin-Cohen, R.4    Tammariello, R.5    Hale, M.6    Dasilva, L.7
  • 24
    • 33846131223 scopus 로고    scopus 로고
    • A rapid, three-step process for the preformulation of a recombinant ricin toxin A-chain vaccine
    • DOI 10.1002/jps.20675
    • Peek LJ, Brey RN, Middaugh CR. 2007. A rapid, three-step process for the preformulation of a recombinant ricin toxin A-chain vaccine. J. Pharm. Sci. 96:44-60. (Pubitemid 46087338)
    • (2007) Journal of Pharmaceutical Sciences , vol.96 , Issue.1 , pp. 44-60
    • Peek, L.J.1    Brey, R.N.2    Middaugh, C.R.3
  • 25
    • 0036956623 scopus 로고    scopus 로고
    • Identification of hypoglycemia in mice as a surrogate marker of ricin toxicosis
    • Pincus SH, Eng L, Cooke CL, Maddaloni M. 2002. Identification of hypoglycemia in mice as a surrogate marker of ricin toxicosis. Comp. Med. 52:530-533. (Pubitemid 36091703)
    • (2002) Comparative Medicine , vol.52 , Issue.6 , pp. 530-533
    • Pincus, S.H.1    Eng, L.2    Cooke, C.L.3    Maddaloni, M.4
  • 26
    • 73449123743 scopus 로고    scopus 로고
    • A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin
    • Neal LM, O'Hara J, Brey RN, III, Mantis NJ. 2010. A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin. Infect. Immun. 78:552-561.
    • (2010) Infect. Immun. , vol.78 , pp. 552-561
    • Neal, L.M.1    O'Hara, J.2    Brey III, R.N.3    Mantis, N.J.4
  • 28
    • 35348968868 scopus 로고    scopus 로고
    • Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation
    • DOI 10.1586/14760584.6.5.685
    • Hem SL, Hogenesch H. 2007. Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation. Expert Rev. Vaccines 6:685-698. (Pubitemid 47607846)
    • (2007) Expert Review of Vaccines , vol.6 , Issue.5 , pp. 685-698
    • Hem, S.L.1    Hogenesch, H.2
  • 29
    • 77954762107 scopus 로고    scopus 로고
    • Preformulation studies: The next advance in aluminum adjuvant-containing vaccines
    • Hem SL, HogenEsch H, Middaugh CR, Volkin DB. 2010. Preformulation studies: the next advance in aluminum adjuvant-containing vaccines. Vaccine 28:4868-4870.
    • (2010) Vaccine , vol.28 , pp. 4868-4870
    • Hem, S.L.1    HogenEsch, H.2    Middaugh, C.R.3    Volkin, D.B.4
  • 31
    • 0028102678 scopus 로고
    • Identification and characterization of a monoclonal antibody that neutralizes ricin toxicity in vitro and in vivo
    • Lemley PV, Amanatides P, Wright DC. 1994. Identification and characterization of a monoclonal antibody that neutralizes ricin toxicity in vitro and in vivo. Hybridoma 13:417-421. (Pubitemid 24351544)
    • (1994) Hybridoma , vol.13 , Issue.5 , pp. 417-421
    • Lemley, P.V.1    Amanatides, P.2    Wright, D.C.3
  • 32
    • 84864055517 scopus 로고    scopus 로고
    • Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant alpha-helix in ricin toxin's enzymatic subunit
    • Vance DJ, Mantis NJ. 2012. Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant alpha-helix in ricin toxin's enzymatic subunit. Toxicon 60:874-877.
    • (2012) Toxicon , vol.60 , pp. 874-877
    • Vance, D.J.1    Mantis, N.J.2
  • 33
    • 79952467216 scopus 로고    scopus 로고
    • Introduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogen
    • Compton JR, Legler PM, Clingan BV, Olson MA, Millard CB. 2011. Introduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogen. Proteins 79:1048-1060.
    • (2011) Proteins , vol.79 , pp. 1048-1060
    • Compton, J.R.1    Legler, P.M.2    Clingan, B.V.3    Olson, M.A.4    Millard, C.B.5


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