Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine

PLoS Genetics

Volumn 10, Issue 7, 2014, Pages

  Holik, Aliaksei Z ^a,b   Young, Madeleine ^a   Krzystyniak, Joanna ^a   Williams, Geraint T ^c   Metzger, Daniel ^d   Shorning, Boris Y ^a   Clarke, Alan R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA NAPHTHOFLAVONE; BRG1 PROTEIN; CRE RECOMBINASE; TAMOXIFEN; WNT PROTEIN; DNA HELICASE; NUCLEAR PROTEIN; SMARCA4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APC GENE; ARTICLE; BRG1 GENE; CANCER CELL LINE; CANCER PREVENTION; CARCINOGENESIS; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENE LOSS; GENE TARGETING; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM; INTESTINE POLYP; INTESTINE STEM CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANETH CELL; PHENOTYPE; PROTEIN FUNCTION; SMALL INTESTINE CANCER; STEM CELL; TRANSGENE; WNT SIGNALING PATHWAY; ADENOMA; ANIMAL; BIOSYNTHESIS; CANCER STEM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; SMALL INTESTINE;

ADENOMA; ANIMALS; CARCINOGENESIS; DNA HELICASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTESTINAL MUCOSA; INTESTINE, SMALL; MICE; NEOPLASTIC STEM CELLS; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS; WNT SIGNALING PATHWAY;

EID: 84905454827     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004453     Document Type: Article

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