-
1
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998; 392: 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
-
2
-
-
70350689923
-
Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release
-
Berger AK, Cortese GP, Amodeo KD, Weihofen A, Letai A, LaVoie MJ. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Hum Mol Genet 2009; 18: 4317-4328
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4317-4328
-
-
Berger, A.K.1
Cortese, G.P.2
Amodeo, K.D.3
Weihofen, A.4
Letai, A.5
Lavoie, M.J.6
-
4
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci USA 2003; 100: 4078-4083
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
5
-
-
2542560342
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
-
Pesah Y, Pham T, Burgess H, Middlebrooks B, Verstreken P, Zhou Y et al. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 2004; 131: 2183-2194
-
(2004)
Development
, vol.131
, pp. 2183-2194
-
-
Pesah, Y.1
Pham, T.2
Burgess, H.3
Middlebrooks, B.4
Verstreken, P.5
Zhou, Y.6
-
6
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios F, Corti O, Lucking CB, Hampe C, Muriel MP, Abbas N et al. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria- dependent cell death. Hum Mol Genet 2003; 12: 517-526
-
(2003)
Hum Mol Genet
, vol.12
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.P.5
Abbas, N.6
-
7
-
-
84863611344
-
Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein
-
Kemeny S, Dery D, Loboda Y, Rovner M, Lev T, Zuri D et al. Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein. PLoS One 2012; 7: e38837
-
(2012)
PLoS One
, vol.7
-
-
Kemeny, S.1
Dery, D.2
Loboda, Y.3
Rovner, M.4
Lev, T.5
Zuri, D.6
-
8
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen D-F, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008; 183: 795-803
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.-F.3
Youle, R.J.4
-
9
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra DP, Jin SM, Tanaka A, Suen D-F, Gautier CA, Shen J et al. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol 2010; 8: e1000298
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.-F.4
Gautier, C.A.5
Shen, J.6
-
10
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
Jurgensmeier JM, Xie Z, Deveraux Q, Ellerby L, Bredesen D, Reed JC. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci USA 1998; 95: 4997-5002
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Xie, Z.2
Deveraux, Q.3
Ellerby, L.4
Bredesen, D.5
Reed, J.C.6
-
11
-
-
84876886863
-
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
-
Muller-Rischart AK, Pilsl A, Beaudette P, Patra M, Hadian K, Funke M et al. The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell 2013; 49: 908-921
-
(2013)
Mol Cell
, vol.49
, pp. 908-921
-
-
Muller-Rischart, A.K.1
Pilsl, A.2
Beaudette, P.3
Patra, M.4
Hadian, K.5
Funke, M.6
-
12
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP et al. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 2013; 496: 372-376
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
-
13
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol 2010; 189: 211-221
-
(2010)
J Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
-
14
-
-
79957472437
-
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
-
Yoshii SR, Kishi C, Ishihara N, Mizushima N. Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem 2011; 286: 19630-19640
-
(2011)
J Biol Chem
, vol.286
, pp. 19630-19640
-
-
Yoshii, S.R.1
Kishi, C.2
Ishihara, N.3
Mizushima, N.4
-
15
-
-
79953231682
-
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: Implication of dysregulated mitochondrial dynamics in Parkinson disease
-
Wang H, Song P, Du L, Tian W, Yue W, Liu M et al. Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem 2011; 286: 11649-11658
-
(2011)
J Biol Chem
, vol.286
, pp. 11649-11658
-
-
Wang, H.1
Song, P.2
Du, L.3
Tian, W.4
Yue, W.5
Liu, M.6
-
16
-
-
84858701257
-
Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons
-
Cai Q, Zakaria HM, Simone A, Sheng Z-H. Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons. Curr Biol 2012; 22: 545-552
-
(2012)
Curr Biol
, vol.22
, pp. 545-552
-
-
Cai, Q.1
Zakaria, H.M.2
Simone, A.3
Sheng, Z.-H.4
-
17
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky FH, Lee S, Wibom R, Olson L, Larsson NG. Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc Natl Acad Sci USA 2011; 108: 12937-12942
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
18
-
-
84868110583
-
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons
-
Lee S, Sterky FH, Mourier A, Terzioglu M, Cullheim S, Olson L et al. Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet 2012; 21: 4827-4835
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4827-4835
-
-
Lee, S.1
Sterky, F.H.2
Mourier, A.3
Terzioglu, M.4
Cullheim, S.5
Olson, L.6
-
19
-
-
79551603345
-
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
-
Van Laar VS, Arnold B, Cassady SJ, Chu CT, Burton EA, Berman SB. Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum Mol Genet 2011; 20: 927-940
-
(2011)
Hum Mol Genet
, vol.20
, pp. 927-940
-
-
Van Laar, V.S.1
Arnold, B.2
Cassady, S.J.3
Chu, C.T.4
Burton, E.A.5
Berman, S.B.6
-
20
-
-
33646114508
-
Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline
-
Casarejos MJ, Menendez J, Solano RM, Rodriguez-Navarro JA, J. Garcia de Yebenes, Mena MA. Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. J Neurochem 2006; 97: 934-946
-
(2006)
J Neurochem
, vol.97
, pp. 934-946
-
-
Casarejos, M.J.1
Menendez, J.2
Solano, R.M.3
Rodriguez-Navarro, J.A.4
Yebenes De J.Garcia5
Mena, M.A.6
-
21
-
-
0026781572
-
A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin
-
Crawford GD, Le WD, Smith RG, Xie WJ, Stefani E, Appel SH. A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. J Neurosci 1992; 12: 3392-3398
-
(1992)
J Neurosci
, vol.12
, pp. 3392-3398
-
-
Crawford, G.D.1
Le, D.W.2
Smith, R.G.3
Xie, W.J.4
Stefani, E.5
Appel, S.H.6
-
22
-
-
30744443484
-
Dopamine covalently modifies and functionally inactivates parkin
-
LaVoie MJ, Ostaszewski BL, Weihofen A, Schlossmacher MG, Selkoe DJ. Dopamine covalently modifies and functionally inactivates parkin. Nat Med 2005; 11: 1214-1221
-
(2005)
Nat Med
, vol.11
, pp. 1214-1221
-
-
Lavoie, M.J.1
Ostaszewski, B.L.2
Weihofen, A.3
Schlossmacher, M.G.4
Selkoe, D.J.5
-
23
-
-
33847191686
-
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling
-
Henn IH, Bouman L, Schlehe JS, Schlierf A, Schramm JE, Wegener E et al. Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling. J Neurosci 2007; 27: 1868-1878
-
(2007)
J Neurosci
, vol.27
, pp. 1868-1878
-
-
Henn, I.H.1
Bouman, L.2
Schlehe, J.S.3
Schlierf, A.4
Schramm, J.E.5
Wegener, E.6
-
24
-
-
84876213313
-
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
-
Vincow ES, Merrihew G, Thomas RE, Shulman NJ, Beyer RP, MacCoss MJ et al. The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo. Proc Natl Acad Sci USA 2013; 110: 6400-6405
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6400-6405
-
-
Vincow, E.S.1
Merrihew, G.2
Thomas, R.E.3
Shulman, N.J.4
Beyer, R.P.5
Maccoss, M.J.6
-
25
-
-
84897863239
-
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
-
McLelland GL, Soubannier V, Chen CX, McBride HM, Fon EA. Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J 2014; 33: 282-295
-
(2014)
EMBO J
, vol.33
, pp. 282-295
-
-
McLelland, G.L.1
Soubannier, V.2
Chen, C.X.3
McBride, H.M.4
Fon, E.A.5
-
26
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
-
Chan NC, Salazar AM, Pham AH, Sweredoski MJ, Kolawa NJ, Graham RL et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 2011; 20: 1726-1737
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
-
27
-
-
70449519412
-
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease
-
da Costa CA, Sunyach C, Giaime E, West A, Corti O, Brice A et al. Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nat Cell Biol 2009; 11: 1370-1375
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1370-1375
-
-
Da Costa, C.A.1
Sunyach, C.2
Giaime, E.3
West, A.4
Corti, O.5
Brice, A.6
-
28
-
-
84875730994
-
Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription
-
Duplan E, Sevalle J, Viotti J, Goiran T, Bauer C, Renbaum P et al. Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription. J Mol Cell Biol 2013; 5: 132-142
-
(2013)
J Mol Cell Biol
, vol.5
, pp. 132-142
-
-
Duplan, E.1
Sevalle, J.2
Viotti, J.3
Goiran, T.4
Bauer, C.5
Renbaum, P.6
-
29
-
-
84898010577
-
Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity
-
Viotti J, Duplan E, Caillava C, Condat J, Goiran T, Giordano C et al. Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity. Oncogene 2013; 33: 1764-1775
-
(2013)
Oncogene
, vol.33
, pp. 1764-1775
-
-
Viotti, J.1
Duplan, E.2
Caillava, C.3
Condat, J.4
Goiran, T.5
Giordano, C.6
-
31
-
-
34547629939
-
A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax
-
George NM, Evans JJD, Luo X. A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax. Genes Dev 2007; 21: 1937-1948
-
(2007)
Genes Dev
, vol.21
, pp. 1937-1948
-
-
George, N.M.1
Evans, J.J.D.2
Luo, X.3
-
32
-
-
78649653044
-
Parkin mono-ubiquitinates Bcl-2 and regulates autophagy
-
Chen D, Gao F, Li B, Wang H, Xu Y, Zhu C et al. Parkin mono-ubiquitinates Bcl-2 and regulates autophagy. J Biol Chem 2010; 285: 38214-38223
-
(2010)
J Biol Chem
, vol.285
, pp. 38214-38223
-
-
Chen, D.1
Gao, F.2
Li, B.3
Wang, H.4
Xu, Y.5
Zhu, C.6
-
33
-
-
77956252454
-
Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitinp62- mediated mitochondrial priming
-
Ding WX, Ni HM, Li M, Liao Y, Chen X, Stolz DB et al. Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitinp62- mediated mitochondrial priming. J Biol Chem 2010; 285: 27879-27890
-
(2010)
J Biol Chem
, vol.285
, pp. 27879-27890
-
-
Ding, W.X.1
Ni, H.M.2
Li, M.3
Liao, Y.4
Chen, X.5
Stolz, D.B.6
-
34
-
-
0037069388
-
Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member
-
Qiu XB, Goldberg AL. Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3. Proc Natl Acad Sci USA 2002; 99: 14843-14848
-
(2002)
ErbB3. Proc Natl Acad Sci USA
, vol.99
, pp. 14843-14848
-
-
Qiu, X.B.1
Goldberg, A.L.2
-
35
-
-
24144470504
-
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin
-
Sriram SR, Li X, Ko HS, Chung KK, Wong E, Lim KL et al. Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. Hum Mol Genet 2005; 14: 2571-2586
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2571-2586
-
-
Sriram, S.R.1
Li, X.2
Ko, H.S.3
Chung, K.K.4
Wong, E.5
Lim, K.L.6
-
36
-
-
46649117176
-
Aberrant folding of pathogenic Parkin mutants: Aggregation versus degradation
-
Schlehe JS, Lutz AK, Pilsl A, Lammermann K, Grgur K, Henn IH et al. Aberrant folding of pathogenic Parkin mutants: aggregation versus degradation. J Biol Chem 2008; 283: 13771-13779
-
(2008)
J Biol Chem
, vol.283
, pp. 13771-13779
-
-
Schlehe, J.S.1
Lutz, A.K.2
Pilsl, A.3
Lammermann, K.4
Grgur, K.5
Henn, I.H.6
-
37
-
-
0033713002
-
Structure of Bax: Coregulation of dimer formation and intracellular localization
-
Suzuki M, Youle RJ, Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell 2000; 103: 645-654
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
38
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 1997; 139: 1281-1292
-
(1997)
J Cell Biol
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
Nechushtan, A.4
Xi, X.G.5
Youle, R.J.6
-
39
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell death
-
Nechushtan A, Smith CL, Hsu YT, Youle RJ. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBOJ 1999; 18: 2330-2341
-
(1999)
EMBOJ
, vol.18
, pp. 2330-2341
-
-
Nechushtan, A.1
Smith, C.L.2
Hsu, Y.T.3
Youle, R.J.4
-
40
-
-
0345490853
-
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe
-
French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease
-
Abbas N, Lucking CB, Ricard S, Durr A, Bonifati V, Michele GD et al. A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Hum Mol Genet 1999; 8: 567-574
-
(1999)
Hum Mol Genet
, vol.8
, pp. 567-574
-
-
Abbas, N.1
Lucking, C.B.2
Ricard, S.3
Durr, A.4
Bonifati, V.5
Michele, G.D.6
-
41
-
-
0031660082
-
Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing
-
Wang K, Gross A, Waksman G, Korsmeyer SJ. Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol Cell Biol 1998; 18: 6083-6089
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6083-6089
-
-
Wang, K.1
Gross, A.2
Waksman, G.3
Korsmeyer, S.J.4
-
42
-
-
84879251778
-
Structure of parkin reveals mechanisms for ubiquitin ligase activation
-
Trempe JF, Sauve V, Grenier K, Seirafi M, Tang MY, Menade M et al. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science 2013; 340: 1451-1455
-
(2013)
Science
, vol.340
, pp. 1451-1455
-
-
Trempe, J.F.1
Sauve, V.2
Grenier, K.3
Seirafi, M.4
Tang, M.Y.5
Menade, M.6
-
43
-
-
84881477223
-
Structure of the human Parkin ligase domain in an autoinhibited state
-
Wauer T, Komander D. Structure of the human Parkin ligase domain in an autoinhibited state. EMBO J 2013; 32: 2099-2112
-
(2013)
EMBO J
, vol.32
, pp. 2099-2112
-
-
Wauer, T.1
Komander, D.2
-
44
-
-
84879674444
-
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
-
Riley BE, Lougheed JC, Callaway K, Velasquez M, Brecht E, Nguyen L et al. Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nat Commun 2013; 4: 1982
-
(2013)
Nat Commun
, vol.4
, pp. 1982
-
-
Riley, B.E.1
Lougheed, J.C.2
Callaway, K.3
Velasquez, M.4
Brecht, E.5
Nguyen, L.6
-
45
-
-
0033713002
-
Structure of Bax: Coregulation of dimer formation and intracellular localization
-
Suzuki M, Youle RJ, Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell 2000; 103: 645-654
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
46
-
-
0037070160
-
Involvement of the N-terminus of Bax in its intracellular localization and function
-
Cartron PF, Moreau C, Oliver L, Mayat E, Meflah K, Vallette FM. Involvement of the N-terminus of Bax in its intracellular localization and function. FEBS Lett 2002; 512: 95-100
-
(2002)
FEBS Lett
, vol.512
, pp. 95-100
-
-
Cartron, P.F.1
Moreau, C.2
Oliver, L.3
Mayat, E.4
Meflah, K.5
Vallette, F.M.6
-
47
-
-
79953192533
-
Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis
-
Czabotar PE, Lee EF, Thompson GV, Wardak AZ, Fairlie WD, Colman PM. Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis. J Biol Chem 2011; 286: 7123-7131
-
(2011)
J Biol Chem
, vol.286
, pp. 7123-7131
-
-
Czabotar, P.E.1
Lee, E.F.2
Thompson, G.V.3
Wardak, A.Z.4
Fairlie, W.D.5
Colman, P.M.6
-
48
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
Goping IS, Gross A, Lavoie JN, Nguyen M, Jemmerson R, Roth K et al. Regulated targeting of BAX to mitochondria. J Cell Biol 1998; 143: 207-215
-
(1998)
J Cell Biol
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
-
50
-
-
79957665553
-
BAX supports the mitochondrial network, promoting bioenergetics in nonapoptotic cells
-
Boohaker RJ, Zhang G, Carlson AL, Nemec KN, Khaled AR. BAX supports the mitochondrial network, promoting bioenergetics in nonapoptotic cells. Am J Physiol Cell Physiol 2011; 300: C1466-C1478
-
(2011)
Am J Physiol Cell Physiol
, vol.300
-
-
Boohaker, R.J.1
Zhang, G.2
Carlson, A.L.3
Nemec, K.N.4
Khaled, A.R.5
-
51
-
-
79956210669
-
Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission
-
Jiao S, Li Z. Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission. Neuron 2011; 70: 758-772
-
(2011)
Neuron
, vol.70
, pp. 758-772
-
-
Jiao, S.1
Li, Z.2
-
52
-
-
77951464624
-
IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation
-
Benard G, Neutzner A, Peng G, Wang C, Livak F, Youle RJ et al. IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation. EMBO J 2010; 29: 1458-1471
-
(2010)
EMBO J
, vol.29
, pp. 1458-1471
-
-
Benard, G.1
Neutzner, A.2
Peng, G.3
Wang, C.4
Livak, F.5
Youle, R.J.6
-
53
-
-
62449129138
-
Cell death pathways in Parkinson's disease: Proximal triggers, distal effectors, and final steps
-
Levy OA, Malagelada C, Greene LA. Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps. Apoptosis 2009; 14: 478-500
-
(2009)
Apoptosis
, vol.14
, pp. 478-500
-
-
Levy, O.A.1
Malagelada, C.2
Greene, L.A.3
-
54
-
-
0033756901
-
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton NA. Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol 2000; 166: 29-43
-
(2000)
Exp Neurol
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
55
-
-
0342331476
-
Cell death and apoptosis regulating proteins in Parkinson's disease-A cautionary note
-
Wullner U, Kornhuber J, Weller M, Schulz JB, Loschmann PA, Riederer P et al. Cell death and apoptosis regulating proteins in Parkinson's disease-a cautionary note. Acta Neuropathol 1999; 97: 408-412
-
(1999)
Acta Neuropathol
, vol.97
, pp. 408-412
-
-
Wullner, U.1
Kornhuber, J.2
Weller, M.3
Schulz, J.B.4
Loschmann, P.A.5
Riederer, P.6
-
56
-
-
0142257924
-
BAX proteinimmunoreactivity in midbrain neurons of Parkinson's disease patients
-
Horowitz JM, Pastor DM, Goyal A, Kar S, Ramdeen N, Hallas BH et al. BAX proteinimmunoreactivity in midbrain neurons of Parkinson's disease patients. Brain Res Bull 2003; 62: 55-61
-
(2003)
Brain Res Bull
, vol.62
, pp. 55-61
-
-
Horowitz, J.M.1
Pastor, D.M.2
Goyal, A.3
Kar, S.4
Ramdeen, N.5
Hallas, B.H.6
-
57
-
-
34249947154
-
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
-
Perier C, Bove J, Wu DC, Dehay B, Choi DK, Jackson-Lewis V et al. Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proc Natl Acad Sci USA 2007; 104: 8161-8166
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8161-8166
-
-
Perier, C.1
Bove, J.2
Wu, D.C.3
Dehay, B.4
Choi, D.K.5
Jackson-Lewis, V.6
-
58
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1-2-3,6- tetrahydropyridine mouse model of Parkinson's disease
-
Vila M, Jackson-Lewis V, Vukosavic S, Djaldetti R, Liberatore G, Offen D et al. Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease. Proc Natl Acad Sci USA 2001; 98: 2837-2842
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
Djaldetti, R.4
Liberatore, G.5
Offen, D.6
-
59
-
-
26244460395
-
Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease
-
Biswas SC, Ryu E, Park C, Malagelada C, Greene LA. Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. Neurochem Res 2005; 30: 839-845
-
(2005)
Neurochem Res
, vol.30
, pp. 839-845
-
-
Biswas, S.C.1
Ryu, E.2
Park, C.3
Malagelada, C.4
Greene, L.A.5
-
60
-
-
41249098254
-
Paraquat neurotoxicity is mediated by a Bak-dependent mechanism
-
Fei Q, McCormack AL, Di Monte DA, Ethell DW. Paraquat neurotoxicity is mediated by a Bak-dependent mechanism. J Biol Chem 2008; 283: 3357-3364
-
(2008)
J Biol Chem
, vol.283
, pp. 3357-3364
-
-
Fei, Q.1
McCormack, A.L.2
Di Monte, D.A.3
Ethell, D.W.4
-
61
-
-
33847765450
-
Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model
-
Wilhelm M, Xu Z, Kukekov NV, Gire S, Greene LA. Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. J Biol Chem 2007; 282: 1288-1295
-
(2007)
J Biol Chem
, vol.282
, pp. 1288-1295
-
-
Wilhelm, M.1
Xu, Z.2
Kukekov, N.V.3
Gire, S.4
Greene, L.A.5
-
62
-
-
84861204926
-
PINK1- and Parkin-mediated mitophagy at a glance
-
Jin SM, Youle RJ. PINK1- and Parkin-mediated mitophagy at a glance. J Cell Sci 2012; 125(Pt 4): 795-799
-
(2012)
J Cell Sci
, vol.125
, Issue.PART 4
, pp. 795-799
-
-
Jin, S.M.1
Youle, R.J.2
-
63
-
-
84873843566
-
PTEN-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem (iPS) cell-derived neurons
-
Rakovic A, Shurkewitsch K, Seibler P, Grunewald A, Zanon A, Hagenah J et al. PTEN-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem (iPS) cell-derived neurons. J Biol Chem 2012; 288: 2223-2237
-
(2012)
J Biol Chem
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grunewald, A.4
Zanon, A.5
Hagenah, J.6
-
65
-
-
0344013138
-
High-yield isolation of murine microglia by mild trypsinization
-
Saura J, Tusell JM, Serratosa J. High-yield isolation of murine microglia by mild trypsinization. Glia 2003; 44: 183-189
-
(2003)
Glia
, vol.44
, pp. 183-189
-
-
Saura, J.1
Tusell, J.M.2
Serratosa, J.3
|