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Volumn 44, Issue 9, 2014, Pages 769-774

Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys

Author keywords

CYP; Drug metabolism; Jejunum

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1D1; CYTOCHROME P450 2A; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C76; CYTOCHROME P450 2C9; CYTOCHROME P450 2D; CYTOCHROME P450 2D1; CYTOCHROME P450 2E1; CYTOCHROME P450 2J2; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; ARACHIDONATE EPOXYGENASE; CYTOCHROME P450 1A1; CYTOCHROME P450 3A;

EID: 84905390984     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2014.895882     Document Type: Article
Times cited : (13)

References (28)
  • 1
    • 1942497956 scopus 로고    scopus 로고
    • Cytochromes P450, drugs, and diseases
    • Guengerich FP. (2003). Cytochromes P450, drugs, and diseases. Mol Interv 3:194-204.
    • (2003) Mol Interv , vol.3 , pp. 194-204
    • Guengerich, F.P.1
  • 2
    • 0036138172 scopus 로고    scopus 로고
    • Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes
    • Hashizume T, Imaoka S, Mise M, et al. (2002). Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes. J Pharmacol Exp Ther 300:298-304.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 298-304
    • Hashizume, T.1    Imaoka, S.2    Mise, M.3
  • 3
    • 77956956713 scopus 로고    scopus 로고
    • Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans
    • Iwasaki K, Murayama N, Koizumi R, et al. (2010). Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans. Drug Metab Pharmacokinet 25:388-91.
    • (2010) Drug Metab Pharmacokinet , vol.25 , pp. 388-391
    • Iwasaki, K.1    Murayama, N.2    Koizumi, R.3
  • 4
    • 18344377326 scopus 로고    scopus 로고
    • Cloning of CYP2J2 gene and identification of functional polymorphisms
    • King LM, Ma J, Srettabunjong S, et al. (2002). Cloning of CYP2J2 gene and identification of functional polymorphisms. Mol Pharmacol 61: 840-52.
    • (2002) Mol Pharmacol , vol.61 , pp. 840-852
    • King, L.M.1    Ma, J.2    Srettabunjong, S.3
  • 5
    • 76149089080 scopus 로고    scopus 로고
    • Identification of novel substrates for human cytochrome P450 2J2
    • Lee CA, Neul D, Clouser-Roche A, et al. (2010). Identification of novel substrates for human cytochrome P450 2J2. Drug Metab Dispos 38: 347-56.
    • (2010) Drug Metab Dispos , vol.38 , pp. 347-356
    • Lee, C.A.1    Neul, D.2    Clouser-Roche, A.3
  • 6
    • 0036842039 scopus 로고    scopus 로고
    • Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole
    • Matsumoto S, Hirama T, Matsubara T, et al. (2002). Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole. Drug Metab Dispos 30:1240-5.
    • (2002) Drug Metab Dispos , vol.30 , pp. 1240-1245
    • Matsumoto, S.1    Hirama, T.2    Matsubara, T.3
  • 7
    • 77954298784 scopus 로고    scopus 로고
    • Regional distribution of cytochrome P450 mRNA expression in the liver and small intestine of cynomolgus monkeys
    • Nakanishi Y, Matsushita A, Matsuno K, et al. (2010). Regional distribution of cytochrome P450 mRNA expression in the liver and small intestine of cynomolgus monkeys. Drug Metab Pharmacokinet 25:290-7.
    • (2010) Drug Metab Pharmacokinet , vol.25 , pp. 290-297
    • Nakanishi, Y.1    Matsushita, A.2    Matsuno, K.3
  • 8
    • 79959940681 scopus 로고    scopus 로고
    • Regional distribution of drug-metabolizing enzyme activities in the liver and small intestine of cynomolgus monkey
    • Nakanishi Y, Matsushita A, Matsuno K, et al. (2011). Regional distribution of drug-metabolizing enzyme activities in the liver and small intestine of cynomolgus monkey. Drug Metab Pharmacokinet 26:288-94.
    • (2011) Drug Metab Pharmacokinet , vol.26 , pp. 288-294
    • Nakanishi, Y.1    Matsushita, A.2    Matsuno, K.3
  • 9
    • 84892993251 scopus 로고    scopus 로고
    • Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia
    • Nakanishi Y, Yamashita H, Yoshikawa T, et al. (2013). Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia. Drug Metab Pharmacokinet 28:510-13.
    • (2013) Drug Metab Pharmacokinet , vol.28 , pp. 510-513
    • Nakanishi, Y.1    Yamashita, H.2    Yoshikawa, T.3
  • 10
    • 0842312531 scopus 로고    scopus 로고
    • Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
    • Nelson DR, Zeldin DC, Hoffman SM, et al. (2004). Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics 14:1-18.
    • (2004) Pharmacogenetics , vol.14 , pp. 1-18
    • Nelson, D.R.1    Zeldin, D.C.2    Hoffman, S.M.3
  • 11
    • 79960023245 scopus 로고    scopus 로고
    • Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans
    • Nishimuta H, Sato K, Mizuki Y, et al. (2011). Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans. Drug Metab Pharmacokinet 26:300-6.
    • (2011) Drug Metab Pharmacokinet , vol.26 , pp. 300-306
    • Nishimuta, H.1    Sato, K.2    Mizuki, Y.3
  • 12
    • 58149460403 scopus 로고    scopus 로고
    • Effect of oral ketoconazole on oral and intravenous pharmacokinetics of simvastatin and its acid in cynomolgus monkeys
    • Ogasawara A, Utoh M, Nii K, et al. (2009). Effect of oral ketoconazole on oral and intravenous pharmacokinetics of simvastatin and its acid in cynomolgus monkeys. Drug Metab Dispos 37:122-8.
    • (2009) Drug Metab Dispos , vol.37 , pp. 122-128
    • Ogasawara, A.1    Utoh, M.2    Nii, K.3
  • 13
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura T, Sato R. (1964). The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239: 2370-8.
    • (1964) J Biol Chem , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 15
    • 0032963857 scopus 로고    scopus 로고
    • Cytochrome P-450 1A1 expression in human small bowel: Interindividual variation and inhibition by ketoconazole
    • Paine MF, Schmiedlin-Ren P, Watkins PB. (1999). Cytochrome P-450 1A1 expression in human small bowel: interindividual variation and inhibition by ketoconazole. Drug Metab Dispos 27:360-4.
    • (1999) Drug Metab Dispos , vol.27 , pp. 360-364
    • Paine, M.F.1    Schmiedlin-Ren, P.2    Watkins, P.B.3
  • 16
    • 0029738490 scopus 로고    scopus 로고
    • First-pass metabolism of midazolam by the human intestine
    • Paine MF, Shen DD, Kunze KL, et al. (1996). First-pass metabolism of midazolam by the human intestine. Clin Pharmacol Ther 60:14-24.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 14-24
    • Paine, M.F.1    Shen, D.D.2    Kunze, K.L.3
  • 17
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, et al. (1994). Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414-23.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3
  • 18
    • 42549152142 scopus 로고    scopus 로고
    • Characterization of gastrointestinal drug absorption in cynomolgus monkeys
    • Takahashi M, Washio T, Suzuki N, et al. (2008). Characterization of gastrointestinal drug absorption in cynomolgus monkeys. Mol Pharm 5:340-8.
    • (2008) Mol Pharm , vol.5 , pp. 340-348
    • Takahashi, M.1    Washio, T.2    Suzuki, N.3
  • 19
    • 80054786436 scopus 로고    scopus 로고
    • Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys
    • Uehara S, Murayama N, Nakanishi Y, et al. (2011). Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys. J Pharmacol Exp Ther 339:654-61.
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 654-661
    • Uehara, S.1    Murayama, N.2    Nakanishi, Y.3
  • 20
    • 77955596754 scopus 로고    scopus 로고
    • A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin
    • Uehara S, Murayama N, Yamazaki H, Uno Y. (2010). A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin. Xenobiotica 40:621-9.
    • (2010) Xenobiotica , vol.40 , pp. 621-629
    • Uehara, S.1    Murayama, N.2    Yamazaki, H.3    Uno, Y.4
  • 21
    • 77950791816 scopus 로고    scopus 로고
    • Macaque CYP2C76 encodes cytochrome P450 enzyme not orthologous to any human isozymes
    • Uno Y, Fujino H, Iwasaki K, Utoh M. (2010a). Macaque CYP2C76 encodes cytochrome P450 enzyme not orthologous to any human isozymes. Curr Drug Metab 11:142-52.
    • (2010) Curr Drug Metab , vol.11 , pp. 142-152
    • Uno, Y.1    Fujino, H.2    Iwasaki, K.3    Utoh, M.4
  • 22
    • 77956005186 scopus 로고    scopus 로고
    • Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol and dextromethorphan
    • Uno Y, Uehara S, Kohara S, et al. (2010b). Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol and dextromethorphan. Drug Metab Dispos 38:1486-92.
    • (2010) Drug Metab Dispos , vol.38 , pp. 1486-1492
    • Uno, Y.1    Uehara, S.2    Kohara, S.3
  • 23
    • 33746238122 scopus 로고    scopus 로고
    • CYP2C76, a novel cytochrome P450 in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide and testosterone
    • Uno Y, Fujino H, Kito G, et al. (2006). CYP2C76, a novel cytochrome P450 in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide and testosterone. Mol Pharmacol 70:477-86.
    • (2006) Mol Pharmacol , vol.70 , pp. 477-486
    • Uno, Y.1    Fujino, H.2    Kito, G.3
  • 24
    • 34548640569 scopus 로고    scopus 로고
    • Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: Is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism?
    • Uno Y, Hosaka S, Matsuno K, et al. (2007). Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism? Arch Biochem Biophys 466:98-105.
    • (2007) Arch Biochem Biophys , vol.466 , pp. 98-105
    • Uno, Y.1    Hosaka, S.2    Matsuno, K.3
  • 25
    • 79954557245 scopus 로고    scopus 로고
    • Macaque cytochromes P450: Nomenclature, transcript, gene, genomic structure, and function
    • Uno Y, Iwasaki K, Yamazaki H, Nelson DR. (2011a). Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function. Drug Metab Rev 43:346-61.
    • (2011) Drug Metab Rev , vol.43 , pp. 346-361
    • Uno, Y.1    Iwasaki, K.2    Yamazaki, H.3    Nelson, D.R.4
  • 26
    • 78650689411 scopus 로고    scopus 로고
    • CYP1D1, pseudogenized in human, is expressed and encodes a functional drug-metabolizing enzyme in cynomolgus monkey
    • Uno Y, Uehara S, Murayama N, Yamazaki H. (2011b). CYP1D1, pseudogenized in human, is expressed and encodes a functional drug-metabolizing enzyme in cynomolgus monkey. Biochem Pharmacol 81:442-50.
    • (2011) Biochem Pharmacol , vol.81 , pp. 442-450
    • Uno, Y.1    Uehara, S.2    Murayama, N.3    Yamazaki, H.4
  • 27
    • 35548936928 scopus 로고    scopus 로고
    • Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafurami-dine
    • Wang MZ, Wu JQ, Bridges AS, et al. (2007). Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafurami-dine. Drug Metab Dispos 35:2067-75.
    • (2007) Drug Metab Dispos , vol.35 , pp. 2067-2075
    • Wang, M.Z.1    Wu, J.Q.2    Bridges, A.S.3
  • 28
    • 19444376971 scopus 로고    scopus 로고
    • Drug metabolism and variability among patients in drug response
    • Wilkinson GR. (2005). Drug metabolism and variability among patients in drug response. N Engl J Med 352:2211-21.
    • (2005) N Engl J Med , vol.352 , pp. 2211-2221
    • Wilkinson, G.R.1


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