Copper-catalyzed direct C-2 difluoromethylation of furans and benzofurans: Access to C-2 CF2H derivatives

Journal of Organic Chemistry

Volumn 79, Issue 15, 2014, Pages 7205-7211

  Belhomme, Marie Charlotte ^a   Poisson, Thomas ^a   Pannecoucke, Xavier ^a  

^a UNIVERSITÉ DE ROUEN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; CATALYSIS; COPPER; COPPER COMPOUNDS; ORGANIC POLLUTANTS;

BENZOFURANS; COPPER CATALYZED; FUNCTIONALIZED;

IODINE COMPOUNDS;

2 (BENZYLOXYMETHYL) 5 (DIFLUOROMETHYL)FURAN; 2 (DIFLUOROMETHYL) 3 PHENYLBENZOFURAN; 2 (DIFLUOROMETHYL)BENZOFURAN; 7 PHENYL 8 DIFLUOROMETHYLFURO[2,3 F] 1,3 BENZODIOXOLE; BENZOFURAN DERIVATIVE; COPPER; ETHYL 2 (7 PHENYLFURO[2,3 F] 1,3 BENZODIOXOL 8 YL) 2,2 DIFLUOROACETATE; ETHYL 2 (BENZOFURAN 2 YL) 2,2 DIFLUOROACETATE; ETHYL 2,2 DIFLUORO 2 (3 METHYLBENZOFURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 (3 PHENYLBENZOFURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 (4,5 DIMETHYLFURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 (5 METHYLBENZOFURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 (5 METHYLFURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 (5 PHENYLFURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 (FURAN 2 YL)ACETATE; ETHYL 2,2 DIFLUORO 2 [3 (BENZYLOXYMETHYL)FURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [3 (BROMOPHENYL)BENZOFURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [4 (BENZYLOXYMETHYL)FURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [5 (2 FLUORO 4 METHOXYPHENYL)FURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [5 (4 METHOXYPHENYL)FURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [5 (ACETOXYMETHYL)FURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [5 (BENZYLOXYMETHYL)FURAN 2 YL]ACETATE; ETHYL 2,2 DIFLUORO 2 [5 [(METHOXYMETHOXY)METHYL]FURAN 2 YL]ACETATE; FURAN DERIVATIVE; UNCLASSIFIED DRUG; CUPROUS IODIDE; IODIDE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; DECARBOXYLATION; DIFLUOROMETHYLATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; HYDROGEN BOND; METHYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY;

BENZOFURANS; CATALYSIS; COPPER; FURANS; IODIDES; METHYLATION; MOLECULAR STRUCTURE;

EID: 84905388017     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo5010907     Document Type: Article

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