Microbial transglutaminase treatment in pasta-production does not affect the immunoreactivity of gliadin with celiac disease patients' sera

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 30, 2014, Pages 7604-7611

  Ruh, Tobias ^a   Ohsam, Jürgen ^a   Pasternack, Ralf ^a   Yokoyama, Keiichi ^b   Kumazawa, Yoshiyuki ^b   Hils, Martin ^a  

^a ZEDIRA GMBH   (Germany)

^b AJINOMOTO CO INC   (Japan)

Author keywords

celiac disease; gliadin; microbial transglutaminase; pasta

Indexed keywords

AMINO ACIDS; DISEASES; PATIENT TREATMENT;

ANTIBODY TITERS; CELIAC DISEASE; GLIADIN; IMMUNOBLOTTING; IMMUNOREACTIVITIES; MICROBIAL TRANSGLUTAMINASE; PASTA; RECOGNITION PATTERNS; PASTA PRODUCTION;

ANTIBODIES;

DIPEPTIDE; EPSILON-(GAMMA-GLUTAMYL)-LYSINE; GLIADIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ADOLESCENT; ADULT; AGED; ANTIBODY PRODUCTION; BLOOD; CELIAC DISEASE; CHEMISTRY; CHILD; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; FOOD HANDLING; HUMAN; IMMUNOBLOTTING; IMMUNOLOGY; INFANT; METABOLISM; MIDDLE AGED; PRESCHOOL CHILD; PROCEDURES; STREPTOMYCES; VERY ELDERLY; WHEAT; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODY FORMATION; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; DIPEPTIDES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FOOD HANDLING; GLIADIN; HUMANS; IMMUNOBLOTTING; INFANT; MIDDLE AGED; STREPTOMYCES; TRANSGLUTAMINASES; TRITICUM; YOUNG ADULT;

EID: 84905284806     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf501275c     Document Type: Article

References (41)

1. Reilly, N. R.; Green, P. H. R. Epidemiology and clinical presentations of celiac disease Semin. Immunopathol. 2012, 34, 473-478
2. Dewar, D.; Pereira, S. P.; Ciclitira, P. J. The pathogenesis of coeliac disease Int. J. Biochem. Cell Biol. 2004, 36, 17-24
3. Schuppan, D.; Junker, Y.; Barisani, D. Celiac disease: from pathogenesis to novel therapies Gastroenterology 2009, 137, 1912-1933
4. Shan, L.; Molberg, Ø.; Parrot, I.; Hausch, F.; Filiz, F.; Gray, G. M.; Sollid, L. M.; Khosla, C. Structural basis for gluten intolerance in celiac sprue Science 2002, 297, 2275-2279
5. Vader, L. W.; de Ru, A.; van der Wal, Y.; Kooy, Y. M. C.; Benckhuijsen, W.; Mearin, M. L.; Drijfhout, J. W.; van Veelen, P.; Koning, F. Specificity of tissue transglutaminase explains cereal toxicity in celiac disease J. Exp. Med. 2002, 195, 643-649
6. Stamnaes, J.; Fleckenstein, B.; Sollid, L. M. The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions Biochim. Biophys. Acta 2008, 1784, 1804-1811
7. Molberg, O.; Mcadam, S. N.; Körner, R.; Quarsten, H.; Kristiansen, C.; Madsen, L.; Fugger, L.; Scott, H.; Norén, O.; Roepstorff, P.; Lundin, K. E.; Sjöström, H.; Sollid, L. M. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease Nat. Med. 1998, 4, 713-717
8. Dieterich, W.; Ehnis, T.; Bauer, M.; Donner, P.; Volta, U.; Riecken, E. O.; Schuppan, D. Identification of tissue transglutaminase as the autoantigen of celiac disease Nature 1997, 3, 797-801
9. Aleanzi, M.; Demonte, A. M.; Esper, C.; Garcilazo, S.; Waggener, M. Celiac disease: Antibody recognition against native and selectively deamidated gliadin peptides Clin. Chem. 2001, 47, 2023-2208
10. Hill, I. D. What are the sensitivity and specificity of serologic tests for celiac disease? Do sensitivity and specificity vary in different populations? Gastroenterology 2005, 128, S25-S32
11. Lindfors, K.; Kaukinen, K. Contribution of celiac disease autoantibodies to the disease process Exp. Rev. Clin. Immunol 2012, 8, 151-154
12. Lindfors, K.; Mäki, M.; Kaukinen, K. Transglutaminase 2-targeted autoantibodies in celiac disease: Pathogenetic players in addition to diagnostic tools? Autoimmun. Rev. 2010, 9, 744-749
13. Teesalu, K.; Panarina, M.; Uibo, O.; Uibo, R.; Utt, M. Autoantibodies from patients with celiac disease inhibit transglutaminase 2 binding to heparin/heparan sulfate and interfere with intestinal epithelial cell adhesion Amino Acids 2012, 42, 1055-1064
14. Ando, H.; Adachi, M.; Umeda, K.; Matsuura, A.; Nonaka, M.; Uchio, R.; Tanaka, H.; Motoki, M. Purification and characteristics of a novel transglutaminase derived from microorganisms Agric. Biol. Chem. 1989, 53, 2613-2617
15. Kanaji, T.; Ozaki, H.; Takao, T.; Kawajiri, H.; Ide, H.; Motoki, M.; Shimonishi, Y. Primary structure of microbial transglutaminase from Streptoverticillium sp. Strain s-8112 J. Biol. Chem. 1993, 268, 11565-11572
16. Kuraishi, C.; Yamazaki, K.; Susa, Y. Transglutaminase: Its utilization in the food industry Food Rev. Int. 2001, 17, 221-2456
17. Kieliszek, M.; Misiewicz, A. Microbial transglutaminase and its application in the food industry. A review Folia Microbiol. (Praha). 2014, 59, 241-250
18. Soeda, T.; Yamazaki, K.; Murase, K. A method for producing long-shelf-life noodles distributed at room temperture. Japan Pat. 5,244,887 1993.
19. Gianfrani, C.; Siciliano, R. a; Facchiano, A. M.; Camarca, A.; Mazzeo, M. F.; Costantini, S.; Salvati, V. M.; Maurano, F.; Mazzarella, G.; Iaquinto, G.; Bergamo, P.; Rossi, M. Transamidation of wheat flour inhibits the response to gliadin of intestinal T cells in celiac disease Gastroenterology 2007, 133, 780-789
20. Mazzeo, M. F.; Bonavita, R.; Maurano, F.; Bergamo, P.; Siciliano, R.; Rossi, M. Biochemical modifications of gliadins induced by microbial transglutaminase on wheat flour Biochim. Biophys. Acta 2013, 1830, 5166-5174
21. Skovbjerg, H.; Koch, C.; Anthonsen, D.; Sjöström, H. Deamidation and cross-linking of gliadin peptides by transglutaminases and the relation to celiac disease Biochim. Biophys. Acta 2004, 1690, 220-230
22. Lombardi, E.; Bergamo, P.; Maurano, F.; Bozzella, G.; Luongo, D.; Mazzarella, G.; Rotondi Aufiero, V.; Iaquinto, G.; Rossi, M. Selective inhibition of the gliadin-specific, cell-mediated immune response by transamidation with microbial transglutaminase J. Leukoc. Biol. 2013, 93, 479-488
23. Elli, L.; Roncoroni, L.; Hils, M.; Pasternack, R.; Barisani, D.; Terrani, C.; Vaira, V.; Ferrero, S.; Bardella, M. T. Immunological effects of transglutaminase-treated gluten in coeliac disease Hum. Immunol. 2012, 73, 992-997
24. Bundesinstitut für Risikobewertung. Transglutaminase in Fleischerzeugnissen. 2011, 52, 1-6.
25. Cabrera-Chávez, F.; Rouzaud-Sández, O.; Sotelo-Cruz, N.; Calderón de la Barca, A. M. Transglutaminase treatment of wheat and maize prolamins of bread increases the serum IgA reactivity of celiac disease patients J. Agric. Food Chem. 2008, 56, 1387-1391
26. Cabrera-Chávez, F.; Rouzaud-Sández, O.; Sotelo-Cruz, N.; Calderón de la Barca, A. M. Bovine milk caseins and transglutaminase-treated cereal prolamins are differentially recognized by IgA of celiac disease patients according to their age J. Agric. Food Chem. 2009, 57, 3754-3759
27. Berti, C.; Roncoroni, L.; Falini, M. L.; Caramanico, R.; Dolfini, E.; Bardella, M. T.; Elli, L.; Terrani, C.; Forlani, F. Celiac-related properties of chemically and enzymatically modified gluten proteins J. Agric. Food Chem. 2007, 55, 2482-2488
28. Japan's Specifications and Standards for Food Additives, 7 th ed.; The Ministry of Health and Welfare Reproduced by Japan Food Additives Association: Tokyo, Japan; pp 19-35.
29. Kumazawa, Y.; Seguro, K.; Takamura, M.; Motoki, M. Formation of ε-(γ-glutamyl)lysine cross-link in cured horse mackerel meat induced by drying J. Food Sci. 1993, 58, 1062-1064
30. Wieser, H.; Antes, S.; Seilmeier, W. Quantitative determination of gluten protein types in wheat flour by reversed-phase high-performance liquid chromatography Cereal Chem. 1998, 75, 644-650
31. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 1970, 227, 508-585
32. Blum, H.; Beier, H.; G, H. J. Improved silver staining of plant protein, RNA & DNA in PAA gels Electrophoresis 1987, 8, 93-99
33. Sakamoto, H.; Kumazawa, Y.; Motoki, M. Strength of protein gels prepared with microbial transglutaminase as related to reaction conditions J. Food Sci. 1994, 59, 866-871
34. Sakamoto, H.; Kumazawa, Y.; Toiguchi, S.; Seguro, K.; Soeda, T.; Motoki, M. Gel strength enhancement by addition of microbial transglutaminase during onshore Surimi manutacture J. Food Sci. 1995, 60, 300-304
35. Larré, C.; Denery-Papini, S.; Popineau, Y.; Deshayes, G.; Desserme, C.; Lefebvere, J. Biochemical analysis and rheological properties of gluten modified by transglutaminase Cereal Chem. 2000, 77, 32-38
36. Basman, A.; Köksel, H.; NG, P. K. W. Effects of tranglutaminse on SDS-PAGE patterns of wheat, soy, and barley proteins and their blends J. Food Sci. 2002, 67, 2654-2658
37. Dørum, S.; Qiao, S.-W.; Sollid, L. M.; Fleckenstein, B. A quantitative analysis of transglutaminase 2-mediated deamidation of gluten peptides: Implications for the T-cell response in celiac disease J. Proteome Res. 2009, 8, 1748-1755
38. Volta, U.; Granito, A.; Fiorini, E.; Parisi, C.; Piscaglia, M.; Pappas, G.; Muratori, P.; Bianchi, F. B. Usefulness of antibodies to deamidated gliadin peptides in celiac disease diagnosis and follow-up Dig. Dis. Sci. 2008, 53, 1582-1588
39. Marietta, E.-V.; Rashtak, S.; Murray, J. A. Correlation analysis of celiac sprue tissue transglutaminase and deamidated gliadin IgG/IgA World J. Gastroenterol. 2009, 15, 845-848
40. Husby, S.; Koletzko, S.; Korponay-Szabó, I. R.; Mearin, M. L.; Phillips, A.; Shamir, R.; Troncone, R.; Giersiepen, K.; Branski, D.; Catassi, C.; Lelgeman, M.; Mäki, M.; Ribes-Koninckx, C.; Ventura, A.; Zimmer, K. P. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease J. Pediatr. Gastroenterol. Nutr. 2012, 54, 136-160
41. Rubio-Tapia, A.; Hill, I. D.; Kelly, C. P.; Calderwood, A. H.; Murray, J. A. American college of gastroenterology clinical guideline: Diagnosis and management of celiac disease Am. J. Gastroenterol. 2013, 108, 656-677