TCF2 attenuates FFA-induced damage in islet β-cells by regulating production of insulin and ROS

International Journal of Molecular Sciences

Volumn 15, Issue 8, 2014, Pages 13317-13332

  Quan, Xiaojuan ^a   Zhang, Lin ^a   Li, Yingna ^a   Liang, Chunlian ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Free fatty acids; Insulin; Reactive oxygen species; TCF2; cells

Indexed keywords

FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 1BETA; HNF1B PROTEIN, RAT; HOMEODOMAIN PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PALMITIC ACID; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; SLC2A2 PROTEIN, RAT; STEM CELL FACTOR RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TRANSACTIVATOR PROTEIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PANCREAS ISLET BETA CELL; RAT; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY ACIDS; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HOMEODOMAIN PROTEINS; INSULIN; INSULIN-SECRETING CELLS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-KIT; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 84905227308     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150813317     Document Type: Article

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