The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1829, Issue 11, 2013, Pages 1225-1235

  Pedersen, Kim Brint ^a   Chhabra, Kavaljit H ^a   Nguyen, Van K ^a   Xia, Huijing ^a   Lazartigues, Eric ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ACE2; HNF1 ; Pancreatic islets; Promoter; Renin angiotensin system; Transcriptional regulation

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 1BETA; MESSENGER RNA;

ALLELE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME STRUCTURE; EXON; FEMALE; GENE OVEREXPRESSION; INSULIN RELEASE; INSULINOMA; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; RAT; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

7-(METHOXYCOUMARIN-4-YL)ACETYL-ALA-PRO-LYS(2,4-DINITROPHENYL)-OH; ACE2; ANG; ANGIOTENSIN; ANGIOTENSIN-CONVERTING ENZYME 2; C(T); CYCLE-THRESHOLD; DISTAL PROMOTER TRANSCRIPTS; DPT; EGFP; ENHANCED GREEN FLUORESCENT PROTEIN; HEPATOCYTE NUCLEAR FACTOR 1Α; HEPATOCYTE NUCLEAR FACTOR 1Β; HNF1Α; HNF1Β; MATURITY-ONSET DIABETES OF THE YOUNG; MCA-APK(DNP); MODY; MOI; MULTIPLICITY OF INFECTION; PANCREATIC ISLETS; PPT; PROMOTER; PROXIMAL PROMOTER TRANSCRIPTS; RAS; RELATIVE LIGHT UNITS; RENIN ANGIOTENSIN SYSTEM; RENIN-ANGIOTENSIN SYSTEM; RLU; TRANSCRIPTIONAL REGULATION;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; DNA PRIMERS; EVOLUTION, MOLECULAR; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; PEPTIDYL-DIPEPTIDASE A; RATS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84886027798     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2013.09.007     Document Type: Article

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