PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation

Diabetes

Volumn 62, Issue 10, 2013, Pages 3459-3468

  Guo, Lili ^a   Inada, Akari ^a,b   Aguayo Mazzucato, Cristina ^a   Hollister Lock, Jennifer ^a   Fujitani, Yoshio ^c,d   Weir, Gordon C ^a   Wright, Christopher V E ^c   Sharma, Arun ^a   Bonner Weir, Susan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CAII PROTEIN; CARBONATE DEHYDRATASE II; NEUROPEPTIDE Y; PEPTIDE YY; PROTEIN; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR MAFB; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; INSULIN; MAFA PROTEIN, MOUSE; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR MAF; GLUCOSE BLOOD LEVEL;

ARTICLE; BODY WEIGHT; CELL MATURATION; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO DEVELOPMENT; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; IMMUNOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESPONSE; INSULIN TOLERANCE TEST; MALE; MOUSE; NONHUMAN; PANCREAS DUCT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; CELL GROWTH; CELL SURVIVAL; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); TRANSGENIC MOUSE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS;

ANIMALS; BLOOD GLUCOSE; CELL GROWTH PROCESSES; CELL SURVIVAL; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MAF TRANSCRIPTION FACTORS, LARGE; MICE; MICE, TRANSGENIC; TRANS-ACTIVATORS;

EID: 84891511796     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1833     Document Type: Article

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